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Pressing for PBM Transparency

Pressing for PBM Transparency | Healthcare: reloaded... | Scoop.it
Recent recommendations from a Department of Labor federal advisory panel are giving a boost to the decade-long effort by corporate employee-health plans to get more information from pharmacy benefit managers.
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Healthcare: reloaded...
On the general trends in healthcare, low signals and tectonic moves, those who will shape the contour of the healthcare revolution...
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Breakthrough HIV Vaccine Set to Start Human Trials in 2019

Breakthrough HIV Vaccine Set to Start Human Trials in 2019 | Healthcare: reloaded... | Scoop.it
An experimental vaccine regimen could be the next groundbreaking progress in curing HIV with human trials set to start next year.
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It's Official! Curing Patients Is Bad for Business

It's Official! Curing Patients Is Bad for Business | Healthcare: reloaded... | Scoop.it

Pharmaceutical companies are developing new drugs in only two therapeutic areas these days -- cancer and rare diseases. Why? These are the only therapeutic areas where exorbitant pricing is tolerated by payers.
How exorbitant are we talking about? Most new drugs for cancer and rare diseases are being priced above $400,000 a year per patient. Some drugs are being priced at $1 million per treatment. And prices continue to soar.

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Accelerating Pharmaceutical Discovery

Accelerating Pharmaceutical Discovery | Healthcare: reloaded... | Scoop.it

NewCures at Northwestern University is a novel accelerator poised to prevent that brush-off. It will identify the most promising new potential therapies in development at the University for cancer, depression, pain, Parkinson’s disease and other diseases. Then it will fund outside research to answer the key questions a pharmaceutical company typically requires before it agrees to invest in later-stage development, such as clinical trials.

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MRI Maps of Brain's Visual Cortex Connectivity Point to Mental Illness

MRI Maps of Brain's Visual Cortex Connectivity Point to Mental Illness | Healthcare: reloaded... | Scoop.it

Researchers at Duke University may have identified a way of predicting future (!) onset of mental illness. They used magnetic resonance imaging (MRI) to study how various parts of the brain communicate with each other. What the investigators noticed is that those individuals with a poorly functioning visual cortex, that doesn’t seem to talk well to the rest of the brain, tend to also be the ones that point to higher chances of having mental conditions as measured by a common mental health assessment.

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Medisafe Demonstrates Double-Digit Impact on Medication Adherence in Hypertension Patients

Medisafe, the leading medication management platform with almost four and a half million registered users, released data today showing that, on average, hypertensive patients increase their prescription refills by almost 10% after they start using the company’s mobile app.
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A systematic review and meta‐analysis of randomized controlled trials: Skin‐patch of Chinese herbal medicine for patients with acute gouty arthritis

Nineteen studies met our inclusion criteria. After synthesizing the data, the results showed that skin‐patches of CHM combined with Western medicine seemed to be more effective than Western medicine alone for pain relief in patients with acute gouty arthritis and had fewer adverse events.

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Somna Therapeutics gets approval to sell medical device over the counter

Somna Therapeutics gets approval to sell medical device over the counter | Healthcare: reloaded... | Scoop.it
Somna has been cleared to sell its Reza Band device—which reduces laryngopharyngeal reflux symptoms—over the counter. The Reza Band will no longer require a prescription, and consumers can buy it directly off the company’s website for $169.
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The efficacy of the traditional Chinese medicine Juanbi pill combined with methotrexate in active rheumatoid arthritis: study protocol for a randomized controlled trial

The efficacy of the traditional Chinese medicine Juanbi pill combined with methotrexate in active rheumatoid arthritis: study protocol for a randomized controlled trial | Healthcare: reloaded... | Scoop.it
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by swelling and painful joints, eventually leading to joint destruction. There is still a lack of effective therapy to treat RA. The Juanbi pill is a Chinese medicine that has been widely used to treat active RA in China for hundreds of years, relieving pain and protecting the affected joints from malformation. However, there is no solid evidence to show the effect of the Juanbi pill on the management of active RA.
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Amazon Business not selling drugs, but other Amazon groups might

Amazon Business not selling drugs, but other Amazon groups might | Healthcare: reloaded... | Scoop.it
Beeyond's insight:

Amazon could still get into the pharma space in another way, as it still has multiple teams working on health care, including Alexa and the secretive Grand Challenge team, sometimes referred to as "1492."

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The Amazon health playbook

The Amazon health playbook | Healthcare: reloaded... | Scoop.it
Yesterday, Amazon announced it is starting a healthcare company with Berkshire Hathaway and JPMorgan. There aren’t any real details yet, but across the board $30B in market cap for healthcare companies was vaporized! Amazon delivery is fast, especially when it’s a dropkick to your stock price.
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Medigene proposes alternative approach to CAR-T technology

Medigene has developed a technology to treat TCR lymphocytes, utilizing the know-how developed by Trianta Therapies, acquired in 2014. Thanks to TCR technology, lymphocytes individuate the antigens developed by cancer cells.
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Drug Doesn't Work? Get Your Money Back! - A Sucker's Bet...

Drug Doesn't Work? Get Your Money Back! - A Sucker's Bet... | Healthcare: reloaded... | Scoop.it
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Outcomes-based contracts, whereby the cost of a drug is reimbursed if the drug doesn't work sounds like a great idea. But as F. Perry Wilson, MD MSCE reports in this Deep Dive analysis, the deal may be a sucker's bet.

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Apple reveals 39 hospitals to launch Apple Health Records

Apple reveals 39 hospitals to launch Apple Health Records | Healthcare: reloaded... | Scoop.it
Stanford Medicine, Scripps, Partners Ochsner Health, Vanderbilt and Duke University are among the hospitals launching the Apple Health Records today.
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Weighing the Cost and Value of CAR T-Cell Therapy

Weighing the Cost and Value of CAR T-Cell Therapy | Healthcare: reloaded... | Scoop.it

Although promising findings are generating much enthusiasm for CAR T-cell therapy, it is tempered by their hefty price tags: $475,000 for tisagenlecleucel and $373,000 for axicabtagene ciloleucel. And these prices reflect just the cost of extracting a patient’s T cells, engineering them to produce CARs on the surface of the cells, and infusing the cells back into the patient. They do not include fees for hospital stays, supportive care, or physician visits, which could drive the total cost to stratospheric levels of more than $1 million per patient, according to some reports.

Beeyond's insight:

Challenges associated with the pricing and reimbursement of CAR T-cell therapies remain and could become heightened as additional indications for these therapies are granted FDA approval and the population of eligible patients increases.

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Inviting pharma to the dance

Inviting pharma to the dance | Healthcare: reloaded... | Scoop.it

NewCures disrupts ‘valley of death’ by de-risking drugs for pharmaceutical and biomedical partnerships.

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Magnetic Stimulation Could Improve Walking Speed of Stroke Victims

Magnetic Stimulation Could Improve Walking Speed of Stroke Victims | Healthcare: reloaded... | Scoop.it
Repetitive Transcranial Magnetic Stimulation (rTMS) could improve walking speed of stroke survivors who have had their walking speed affected, finds a new study. The findings of this study are published in the American Journal of Physical Medicine & Rehabilitation.
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Meet Today's Healthcare Team: Patients + Doctors + Machines

Meet Today's Healthcare Team: Patients + Doctors + Machines | Healthcare: reloaded... | Scoop.it

Several healthcare technology advancements are converging to deliver significant benefits to consumers. According to Accenture research, healthcare consumers continue to show strong use of digital technology for self-service care – and the numbers are rising each year. In 2018, 75 percent of US consumers surveyed said technology is important to managing their health. Patients are increasingly open to intelligent technologies taking on elements of their care, such as medical consultations and monitoring. And they are using self-service digital health tools that go beyond websites.

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Medisafe Proves Its Self-Reported Adherence Data Are Consistent with Prescription Refill Claims

The results show that the medication possession ratio (MPR) for Medisafe users taking antihypertensives and novel oral anticoagulants (NOACs) is on average 7 to 9% higher than the adherence they report on Medisafe. MPR is a standard metric used by the healthcare industry to track adherence based on prescription claims.
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Harnessing the Digital Exhaust: Incorporating Wellness into the Pharma Model

Harnessing the Digital Exhaust: Incorporating Wellness into the Pharma Model | Healthcare: reloaded... | Scoop.it
The increasing availability of devices capable of tracking biomarkers presents major opportunities in contemporary healthcare. Herein we advocate a new role for the pharmaceutical industry to capitalize on these opportunities and, in doing so, incorporate wellness and patient engagement programs into their standard business models. Medical-grade decision-making using diagnostic, prognostic, and monitoring biomarkers will require coordinated approaches between the pharmaceutical and technology industries and the careful design of longitudinal clinical studies to validate their efficacy.
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Harvard’s Wyss Institute Partners with Cellectis to Recode the Human Genome

Harvard’s Wyss Institute Partners with Cellectis to Recode the Human Genome | Healthcare: reloaded... | Scoop.it
Recode project will use Cellectis’ TALEN gene editing technology to create first virus-resistant human cells for manufacturing therapeutics and developing new cell-based therapies.
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NPPA: syringes being sold at prices far above manufacturing costs

NPPA: syringes being sold at prices far above manufacturing costs | Healthcare: reloaded... | Scoop.it
In the case of insulin syringes with needles, the average price to distributors was Rs2.68, with average MRP at Rs7.92 and maximum trade margin at 400%
Beeyond's insight:

The NPPA data comes nearly a month after the regulator revisited the prices of cardiac stents, which was slashed by up to 85% in February 2017 to make them affordable. It is, however, not clear whether Tuesday’s data was released ahead of a price cap on needles and syringes. The regulator had earlier asked for trade data on 18 other medical devices.

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Trends for Digital Health 2018

Trends for Digital Health 2018 | Healthcare: reloaded... | Scoop.it
We take a look at the healthcare trends bubbling up in 2018. We'll analyze patents, recent investments, earnings calls, and more to look for potential areas of opportunity including underserved populations, new monitoring techniques, and more.
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Scientists Discover New Human Organ 'Interstitium'

Scientists Discover New Human Organ 'Interstitium' | Healthcare: reloaded... | Scoop.it

In a landmark discovery the US scientists have identified a new organ in human beings consisting of a network of fluid-filled compartments that act like shock absorbers. This previously undiscovered organ which has been dubbed as ‘interstitium’ by the researchers protects tissues of vital organs from tearing.

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Genetics Business Does Not Need A Cheerleader

Genetics Business Does Not Need A Cheerleader | Healthcare: reloaded... | Scoop.it
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It's one of the rare industry segments that prompts declarations of affection from patients, physicians, pharmacists and payers, if not companies with big-selling products approaching their patent D-Day.
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Why Netflix and Amazon might offer a glimpse at our future healthcare ecosystems

Why Netflix and Amazon might offer a glimpse at our future healthcare ecosystems | Healthcare: reloaded... | Scoop.it

“Similar to how Amazon reminds you of purchases or makes recommendations to you, an AI that understands meaning and context can provide appropriate recommendations based on your body weight, your age, your medical history and so on”.
Clark points out that this degree of contextual information, based on constant data gathering and user input, could deliver superior contextualisation than a patient might get from a one-time meeting with a clinician.

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