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▶ Improving Trial Accrual by Engaging the Digital Healthcare Consumer

Clinical trials are unable to answer important treatment questions, often due to the inability to recruit patient participants. Recent data suggests nearly 50% of cancer clinical trials close early due to lack of accrual. Trailblazing physicians like Dr. BJ Rimel of Cedars-Sinai Medical Center show us innovative ways to use technology to help. Dr. Rimel and the Women’s Cancer Program at Cedars-Sinai Medical Center have increased trial accrual by implementing an online registry to link participants to research studies. The online registry increased accrual by nearly 5x over the past year by digitizing and simplifying a previously cumbersome, paper-based process. Learn how using e-consents and social marketing improved patient engagement and enrollment in the Research for Her online registry, helping physicians engage a broader population and advance research while saving time and reducing costs. View Research for Her in action and learn how your organization can improve enrollment with DocuSign’s consumer and mobile-friendly digital transaction management platform.
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Healthcare: reloaded...
On the general trends in healthcare, low signals and tectonic moves, those who will shape the contour of the healthcare revolution...
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Vaccines and California's Science Deniers

Vaccines and California's Science Deniers | Healthcare: reloaded... | Scoop.it

Childhood vaccinations are one of the rare areas where the rest of the U.S. would do well to follow California’s lead. And the sooner, the better.

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Amazon In Healthcare: The E-Commerce Giant's Strategy For A $3 Trillion Market

Amazon In Healthcare: The E-Commerce Giant's Strategy For A $3 Trillion Market | Healthcare: reloaded... | Scoop.it
Amazon could use its expertise to disrupt everything from the pharmaceutical supply chain to Medicare management. We break down the healthcare areas best suited for an Amazon entrance.
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Supporting the Advancement of Drug-Eluting Devices

Supporting the Advancement of Drug-Eluting Devices | Healthcare: reloaded... | Scoop.it
Drug device combination products are increasingly being used in the treatment and control of medical conditions, as they offer several advantages when compared with drug delivery via oral, injection, and infusion methods. For this reason, drug-eluting medical device products have seen a surge in development, in particular those that elute regular controlled doses of drugs precisely and consistently to a treatment area.
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New Device Vibrates Skull to Diagnose Cause of Dizziness

New Device Vibrates Skull to Diagnose Cause of Dizziness | Healthcare: reloaded... | Scoop.it

Dizziness can be caused by a different underlying health problems, but identifying which is the culprit is not trivial. One technique is called a VEMP test (Vestibular Evoked Myogenic Potentials), which requires the patient to listen to exceedingly loud popping sounds. These sounds, via a natural reflex, trigger the muscles in the eyes and neck to contract momentarily, and these contractions and how quickly they come about can help form a diagnosis.

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Mutant KRAS Gene: A Potential Target to Suppress Associated Cancers

Mutant KRAS Gene: A Potential Target to Suppress Associated Cancers | Healthcare: reloaded... | Scoop.it

RAS is a gene family that makes proteins which control cell growth and cell death in a human body. KRAS, HRAS and NRAS are the members of RAS gene family. This family produces more than 150 proteins. The RAS gene in its mutated (changed) form can be found in one-third of the cancers. This mutated form of RAS gene produces defective proteins, which causes uncontrolled growth of cells leading to cancer, as well as it makes cancer resistant to the existing therapies.

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Blockchain in healthcare: Huge promise, but largely unproven

Blockchain in healthcare: Huge promise, but largely unproven | Healthcare: reloaded... | Scoop.it

Providers and payers are looking at blockchain to solve problems ranging from interoperability to supply chain inefficiencies and getting people to adopt healthy behaviors.

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UK rejects Gilead's CAR-T cancer cell therapy as too expensive

UK rejects Gilead's CAR-T cancer cell therapy as too expensive | Healthcare: reloaded... | Scoop.it
A cutting-edge CAR-T cell therapy for otherwise untreatable forms of blood cancer is too expensive to justify its use on Britain's state-funded health service, the country's healthcare cost agency NICE said on Tuesday.
Beeyond's insight:
“If we’re going to see CAR-T therapy widely available on the NHS, we need to find ways to reduce the costs”. Ok. How?...
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Anti-Vaxxers Are Using Twitter to Manipulate a Vaccine Bill

Anti-Vaxxers Are Using Twitter to Manipulate a Vaccine Bill | Healthcare: reloaded... | Scoop.it
A small group of vocal anti-vaxxers is fighting hard to make sure a vaccine bill doesn't pass.
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There’s no ‘I’ in cure

Finding a cure is no easy feat. And it’s not something that can be done alone. Of course there are scientists who dream of single-handedly discovering a new gene and naming it after themselves. But world-changing breakthroughs requires expertise from different fields, bringing fresh ideas to the table. Today, cardiologists, engineers, computer scientists and the like are joining forces to tackle some of the world’s biggest killers.

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Price caps on knee implants, stents may be replaced by margin restrictions

Price caps on knee implants, stents may be replaced by margin restrictions | Healthcare: reloaded... | Scoop.it

The government is planning to control prices of medical devices by restricting their trade margins, a departure from the existing mechanism of capping prices, two people aware of the matter said. There has been more or less a consensus among government think tank Niti Aayog, the health ministry, department of pharmaceuticals and the department of industrial policy & promotion on regulating trade margins on medical devices, the people said, requesting anonymity.

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Aging of Lab Grown Human Cells Successfully Reversed by New Compounds

Aging of Lab Grown Human Cells Successfully Reversed by New Compounds | Healthcare: reloaded... | Scoop.it
Scientists have used hydrogen sulfide, a naturally occurring molecule, to reverse aging of human cells grown in a lab.
Beeyond's insight:
Aging is a natural process that occurs in all humans as cells decline. One scientific explanation for aging relates to the accumulation of "senescent" cells in tissues and organs.
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The Future Of Clinical Trials: The Promise Of AI And The Role Of Big Tech

The Future Of Clinical Trials: The Promise Of AI And The Role Of Big Tech | Healthcare: reloaded... | Scoop.it
Testing new drugs is a slow, expensive, and manual process. Artificial intelligence has the potential to disrupt every stage of the clinical trials process — from matching eligible patients to studies to monitoring adherence and data collection.
Beeyond's insight:

This year, over 1.7 million people in the United States will be diagnosed with cancer for the first time. At the same time, more than 10,000 clinical trials will look to recruit thousands of new patients for potentially life-saving experimental cancer drugs.

And yet, less than 5% of cancer patients end up enrolling in trials.

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Enhanced Fertility Programme

Enhanced Fertility Programme | Healthcare: reloaded... | Scoop.it
Enhanced Fertility ProgrammeTM has been developed to help you get pregnant faster by improving your health. You will get 1 whole year of support during your journey. The programme is online and has been prepared using evidence-based research, in collaboration with Simulation For Digital Health accelerator at London South Bank University.
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Engineered natural killer cells may be the next great cancer immunotherapy

Engineered natural killer cells may be the next great cancer immunotherapy | Healthcare: reloaded... | Scoop.it

CAR T cells—their name comes from the chimeric antigen receptor, or CAR, added to help the immune cells target cancer cells—inspired the new work. CAR natural killer (CAR NK) cells could be safer, faster to produce, and cheaper, and they may work in situations where T cells falter. CAR-carrying macrophages also have potential advantages, and one firm plans to launch the first clinical trials of these cells next year.

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The Way Drugs Are Sold & Distributed Is Opaque, Inefficient, & Costly. Here's How Companies Are Trying To Fix That.

The Way Drugs Are Sold & Distributed Is Opaque, Inefficient, & Costly. Here's How Companies Are Trying To Fix That. | Healthcare: reloaded... | Scoop.it
From large corporations assuming multiple roles in the drug supply chain — as seen with CVS' pending acquisition of insurer Aetna — to new startups leveraging tech to smooth drug distribution, here's how the complex pharmaceuticals market is changing.
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Focused Ultrasound and Intranasal Drug Delivery for Brain Cancer Therapy

Focused Ultrasound and Intranasal Drug Delivery for Brain Cancer Therapy | Healthcare: reloaded... | Scoop.it
The technique involves administering drugs through an intranasal spray, meaning that the drug can travel directly into the brain along the trigeminal and olfactory nerves. Then, the researchers can use focused ultrasound to allow the drug to penetrate and accumulate in deeper layers of the tissue, and exert therapeutic benefit at the ultrasound-targeted region.
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40+ Companies Using Tech To Get Drugs To Patients More Quickly, Cheaply, & Safely

40+ Companies Using Tech To Get Drugs To Patients More Quickly, Cheaply, & Safely | Healthcare: reloaded... | Scoop.it
The complex pharmaceutical supply chain is ripe for disruption from all angles. Here's how startups are leveraging tech to simplify the process of prescribing and delivering medication.
Beeyond's insight:
The drug supply chain is complicated, opaque, and overcrowded, involving a host of intermediaries that stand between drug manufacturers and the patients they aim to serve. These intermediaries — which include wholesalers, pharmacy benefit managers (PBMs), insurers, and pharmacies — capture $41 of every $100 spent on drugs in a retail pharmacy, and have a combined market cap of almost three-quarters of a trillion dollars.
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How the rise of anti-vaccine and other ‘misinfodemics’ makes us more susceptible to disease

How the rise of anti-vaccine and other ‘misinfodemics’ makes us more susceptible to disease | Healthcare: reloaded... | Scoop.it

The importance — to our health — of becoming digitally savvy is the focus of a provocative article published online Thursday in the Atlantic magazine. The article describes the health-related dangers posed by a phenomenon the article’s authors call misinfodemics — “the spread of a particular health outcome or disease facilitated by viral misinformation.”

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Scientists identify universal influenza vaccine

Scientists identify universal influenza vaccine | Healthcare: reloaded... | Scoop.it

Scientists have found a potential universal influenza vaccine that could protect against most strains of the virus. The vaccine called candidate is described in the journal Nature Communications, received a strong antibody response to a structure on the surface of flu viruses, called the hemagglutinin (HA) stalk. According to researchers, it protected mice from infection by various flu strains. It has the potential to be developed into a universal flu vaccine.

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Alzheimer's Disease May Be Predicted with a Simple Eye Exam

Alzheimer's Disease May Be Predicted with a Simple Eye Exam | Healthcare: reloaded... | Scoop.it
Researchers are developing an early detection method for Alzheimer's Disease that involves a non-invasive eye exam.
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Novel nanoparticle-based approach detects and treats oral plaque without drugs

Novel nanoparticle-based approach detects and treats oral plaque without drugs | Healthcare: reloaded... | Scoop.it
When the good and bad bacteria in our mouth become imbalanced, the bad bacteria form a biofilm (aka plaque), which can cause cavities, and if left untreated over time, can lead to cardiovascular and other inflammatory diseases like diabetes and bacterial pneumonia.
A team of researchers from the University of Illinois has recently devised a practical nanotechnology-based method for detecting and treating the harmful bacteria that cause plaque and lead to tooth decay and other detrimental conditions (Biomaterials, "Dual purpose hafnium oxide nanoparticles offer imaging Streptococcus mutans dental biofilm and fight it In vivo via a drug free approach").
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Home healthcare to be most disruptive trend in India in next decade

Home healthcare to be most disruptive trend in India in next decade | Healthcare: reloaded... | Scoop.it
India is expected to have more than 300 million people over the age of 60 by 2050. Increasing chronic diseases pose main threat. In such a scenario, it is expected that home health services will play a very critical role in contributing towards a healthy India.
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Healthcare’s Future Winners and Losers

Healthcare’s Future Winners and Losers | Healthcare: reloaded... | Scoop.it
Some traditional sectors will see market share fall by 60 percent, and new profit opportunities will emerge in others for companies that can quickly capitalize on them. Companies will need to make targeted investments to navigate this massive change, making tough judgements about which areas of the healthcare value chain will succeed, and which will suffer.
Beeyond's insight:

By far, the biggest future winners in tomorrow’s healthcare landscape will be software and IT companies and outpatient providers. Pharmacy benefits managers (PBMs), distributors and wholesalers, and payers will lose big in a landscape that will be unrecognizable.

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150+ Startups Reshaping The Wellness Industry

150+ Startups Reshaping The Wellness Industry | Healthcare: reloaded... | Scoop.it

Modern-day “wellness” refers to holistic healthy living characterized by physical, mental, social, and spiritual well-being. Whether it’s sipping kombucha or experimenting with the latest CBD oil, wellness has officially invaded our society.
While the industry has seen its share of controversy — debates over goop’s wellness lifestyle suggestions, the infamous death of connected juicer startup Juicero, etc. — consumers, startups, and corporations are placing broad bets across the sector.

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Scientists Now Believe They May be Able to Cure Glaucoma by Restricting Its Autoimmune Activity

Scientists Now Believe They May be Able to Cure Glaucoma by Restricting Its Autoimmune Activity | Healthcare: reloaded... | Scoop.it
A new study asserts that glaucoma might actually be an autoimmune disorder, and the research could lead to new treatments for this neurodegenerative condition.
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