Health & Life Extension
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Health & Life Extension
Documented scientific therapies to help maintain optimal health and slow aging.
Curated by Tonya Scholz
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Anti-malaria drugs have shown promise in treating cancer, and now researchers know why

Anti-malaria drugs have shown promise in treating cancer, and now researchers know why | Health & Life Extension | Scoop.it
Anti-malaria drugs known as chloroquines have been repurposed to treat cancer for decades, but until now no one knew exactly what the chloroquines were targeting when they attack a tumor. Now, researchers from the Abramson Cancer Center of the University of Pennsylvania say they have identified that target—an enzyme called PPT1—opening up a new pathway for potential cancer treatments. The team also used CRISPR/Cas9 gene editing to remove PPT1 from cancer cells in the lab and found that eliminating it slows tumor growth. They detailed a potent chloroquine developed at Penn, known as DC661, that can take advantage of this new treatment pathway. Their findings are published in Cancer Discovery today.
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What if you could live to be 150?

There's a mad rush in the field of regenerative medicine to improve the human healthspan.

 

 

Learn more: https://leapsmag.com/?s=aging

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The Top 8 Things to Know About Anti-Aging Research Right Now

The Top 8 Things to Know About Anti-Aging Research Right Now | Health & Life Extension | Scoop.it
Here’s the Inside Scoop from an Icon in the Longevity Field
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RAADfest: Inside the conference to reverse human aging

RAADfest: Inside the conference to reverse human aging | Health & Life Extension | Scoop.it
Fast Company attends RAADfest, where the faithful rage against the “unnecessary evil” of getting old—and share ways to stay healthy, sharp, and active.
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Resistance Exercise Reduces Cognitive Decline | Life Extension

Resistance Exercise Reduces Cognitive Decline | Life Extension | Health & Life Extension | Scoop.it
Studies show that exercise inhibits neurodegenerative diseases and even promotes neurogenesis,the creation of new brain cells.
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Mobile technologies may help researchers crack the mysteries of aging | Penn State University

Mobile technologies may help researchers crack the mysteries of aging | Penn State University | Health & Life Extension | Scoop.it
A National Institutes of Health (NIH) grant will allow Penn State’s Martin Sliwinski and team to learn more about how small changes in the brain can develop into neurological conditions later in life by developing new standardized mobile technologies for researchers across the U.S. Neil Sharkey, vice president for research at Penn State, said the work will help set the standard for mobile cognitive health research.
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Florida sues Walgreens, CVS over opioid sales - wptv.com

Florida sues Walgreens, CVS over opioid sales - wptv.com | Health & Life Extension | Scoop.it
Florida is suing the nation's two largest drugstore chains, Walgreens and CVS, alleging they added to the state and national opioid crisis by overselling painkillers and not taking precautions to stop illegal sales.
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NAD (Nicotinamide Adenine Dinucleotide): A Complete Guide

NAD (Nicotinamide Adenine Dinucleotide): A Complete Guide | Health & Life Extension | Scoop.it
A complete guide to nicotinamide adenine dinucleotide, the newest supplement for longevity and cellular health.
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Tam Hunt: A Conversation with ‘Forever Man’ Bill Faloon About Fending Off Aging | Homes & Lifestyle - Noozhawk.com

Tam Hunt: A Conversation with ‘Forever Man’ Bill Faloon About Fending Off Aging | Homes & Lifestyle - Noozhawk.com | Health & Life Extension | Scoop.it
Bill Faloon is a man with a mission: to fend off aging. As long as possible, and maybe even forever. A recent Popular Science story called him “the forever man.” This is both because Faloon wants to figure out how we can live forever and because he has been working to resolve this problem for what can seem like forever — or at least since the 1970s, which seems to most of us to be pretty much forever.
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Family tree of 400 million people shows genetics has limited influence on longevity: Study of huge Ancestry.com pedigree set suggests similar life spans between spouses may have inflated previous e...

Family tree of 400 million people shows genetics has limited influence on longevity: Study of huge Ancestry.com pedigree set suggests similar life spans between spouses may have inflated previous e... | Health & Life Extension | Scoop.it
Although long life tends to run in families, genetics has far less influence on life span than previously thought, according to a new analysis of more than 400 million people. The results suggest that the heritability of life span is well below past estimates, which failed to account for our tendency to select partners with similar traits to our own.
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Could Rapamycin Help Humans Live Longer?

Could Rapamycin Help Humans Live Longer? | Health & Life Extension | Scoop.it
From extending lifespan to bolstering the immune system, the drug’s effects are only just beginning to be understood.
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Does dietary restriction protect against age-related leaky gut? | EurekAlert! Science News

Does dietary restriction protect against age-related leaky gut? | EurekAlert! Science News | Health & Life Extension | Scoop.it
Flies on dietary restriction are protected from leaky gut and systemic inflammation as they age. Conversely, flies on a rich diet are more prone to intestinal permeability, developing gaps in the intestinal barrier which are caused by an age-related increase in the death of intestinal epithelial cells. Researchers also looked at dysbiosis as a contributor to leaky gut and concluded that diet may ultimately be the primary driver in cellular changes leading to intestinal permeability.
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Finally, the drug that keeps you young

Finally, the drug that keeps you young | Health & Life Extension | Scoop.it
Anti-aging pioneer Judith Campisi explains how a recent breakthrough could ward off age-related disease.
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2 Sanders-Brown studies show connection between diet and cognitive function – Lane Report | Kentucky Business & Economic News

2 Sanders-Brown studies show connection between diet and cognitive function – Lane Report | Kentucky Business & Economic News | Health & Life Extension | Scoop.it
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Researchers find glycolysis links to gene transcription via NAD+

Researchers find glycolysis links to gene transcription via NAD+ | Health & Life Extension | Scoop.it
A team of researchers at the University of Texas has found NAD+ synthesis and consumption integrate glucose metabolism and adipogenic transcription during adipocyte differentiation. In their paper published in the journal Science, the group describes their research into how glucose is converted into fat in the body and what they found. Sophie Trefely and Kathryn Wellen with the University of Pennsylvania and Drexel University, respectively, offer a Perspective piece on the work done by the team in Texas in the same journal issue.
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The Death of Death - VICE

The Death of Death - VICE | Health & Life Extension | Scoop.it
What young people can learn from a society of aging immortalists trying to live long enough to live forever.
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10 Tricks To Reverse Aging

10 Tricks To Reverse Aging | Health & Life Extension | Scoop.it
Whether cosmetic or emblematic of a deeper health issue, signs of premature aging of the skin, hair, brain or body may add decades to your chronological age. ForbesWoman spoke to dieticians, neurologists and dermatologists to find the 10 best tricks to turn back the clock and reverse premature aging symptoms.
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Consensual Hugs Seem to Reduce Stress

Consensual Hugs Seem to Reduce Stress | Health & Life Extension | Scoop.it
People who had a conflict in a given day but also got hugged were not as affected by the negative interaction as were their unhugged counterparts.  
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Study Hard and You Might Lower Your Chances of Dementia

Study Hard and You Might Lower Your Chances of Dementia | Health & Life Extension | Scoop.it
Learning is essential to our development, and it could be the key to building the cognitive reserves necessary to withstand demential in our golden years.
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A gut bacterium as a fountain of youth? Well, let's start with reversing insulin resistance

A gut bacterium as a fountain of youth? Well, let's start with reversing insulin resistance | Health & Life Extension | Scoop.it
Move over Bifidobacterium and Lactobacillus. There's a new health-promoting gut bacterium in town, and it's called Akkermansia muciniphila.
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NAD can restore mitochondrial function and energy production in MTDPS liver-like cells

NAD can restore mitochondrial function and energy production in MTDPS liver-like cells | Health & Life Extension | Scoop.it
A drug screen using the SPECTRUM library identified candidates that restore energy production in DGUOK-deficient liver-like cells, offering the first potential treatment for MTDPS.
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Reversal Research by Kelsey Moody and An Age Reversal Update by Bill Faloon- via @youtube #livestream

Age Reversal Research by Kelsey Moody An Age Reversal Update by Bill Faloon Age Reversal Research by Kelsey Moody. Mr. Kelsey Moody is a biotechnolog
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A Drug Cocktail Could Help Us Live Longer Healthily –

A Drug Cocktail Could Help Us Live Longer Healthily – | Health & Life Extension | Scoop.it
A mixture of a drug and a supplement reduced the signs of age-related diseases and extended life in mice and human cells.
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'Anti-aging molecule' could improve liver and kidney treatments

'Anti-aging molecule' could improve liver and kidney treatments | Health & Life Extension | Scoop.it
Blocking an enzyme that limits the activity of the 'anti-aging molecule' NAD+ could be a way to protect the liver and kidneys from damage, study suggests.
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Researchers discover how to slow aging

Researchers discover how to slow aging | Health & Life Extension | Scoop.it
Previous research published earlier this year in Nature Medicine involving University of Minnesota Medical School faculty Paul D. Robbins and Laura J. Niedernhofer and Mayo Clinic investigators James L. Kirkland and Tamara Tchkonia, showed it was possible to reduce the burden of damaged cells, termed senescent cells, and extend lifespan and improve health, even when treatment was initiated late in life. They now have shown that treatment of aged mice with the natural product Fisetin, found in many fruits and vegetables, also has significant positive effects on health and lifespan.
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