Science, Technology, and Current Futurism
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Diffusion Tensor Imaging of the Brain

Diffusion tensor imaging (DTI) is a promising method for characterizing microstructural changes or differences with neuropathology and treatment. The diffusion tensor may be used to characterize the magnitude, anisotropy and orientation of the diffusion tensor. This paper reviews the biological mechanisms, acquisition and analysis methodology of DTI measurements. The relationships between DTI measures and white matter pathologic features (ischemia, myelination, axonal damage, inflammation, and edema) are summarized. Applications of DTI to tissue characterization in neurotherapeutic applications are reviewed. The interpretations of common DTI measures – mean diffusivity (MD), fractional anisotropy (FA), radial diffusivity (Dr) and axial diffusivity (Da) – are discussed. In particular, FA is highly sensitive to microstructural changes, but not very specific to the type of changes (e.g., radial or axial). In order to maximize the specificity, it is recommended that future studies use multiple diffusion tensor measures (e.g., MD and FA, or Da and Dr) to better characterize the tissue microstructure.

 
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Julie Kientz | Innovators Under 35 | MIT Technology Review

Julie Kientz | Innovators Under 35 | MIT Technology Review | Science, Technology, and Current Futurism | Scoop.it
If you want to use technology to make life better for people with autism and their families, the trick is to make the technology secondary.

 

"By working as a therapist and talking to others, Kientz identified problems with the paper-based method. One was that multiple therapists might need to review a child’s records, but there was only one copy of the binder filled with hand-marked charts and notes. And with data points trapped on paper, there wasn’t a good way to visualize broader trends or review negative blips in a child’s otherwise positive progress.

 

Kientz’s solution was for therapists to use a digital recording pen and special paper that could digitize their writing. The change was unobtrusive to the therapist and invisible to the child. But notes and chart inputs made their way automatically into a database and were synched with video recordings of each session. This meant therapists could project progress graphs at meetings and pinpoint moments when a child didn’t perform as well as expected. They could immediately access video from that moment in a therapy session; in one instance, therapists reviewed the video and agreed that they each had different standards for a “right” response. As a result, the child was given credit for mastering a skill and could move on to new challenges."

Sharrock's insight:

This systems might have other implications in education. It could be put in the hands of educators who are tracking other behaviors and progress that could help with instruction and intervention decision making in special education--developing functional behavioral assessments, tracking distraction, tracking reading/decoding in running records, math problem solution process, etc. It could also help with the general education classroom and Response to Intervention. Imagine if Google Glass was also "tapped" to support with video recording and augmented reality support.

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Transparent Brain Technique Made Easier : DNews

Transparent Brain Technique Made Easier : DNews | Science, Technology, and Current Futurism | Scoop.it
The CLARITY technique is being used to image donated, postmortem brains from people with autism or epilepsy.
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Five Major Psychiatric Disorders Share Genetic Link

Five Major Psychiatric Disorders Share Genetic Link | Science, Technology, and Current Futurism | Scoop.it
A new study has found that five common psychiatric disorders - bipolar disorder, autism, ADHD, and schizophrenia - have the same genetic risk factors.

Via Dimitris Agorastos
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