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Artificial Intelligence Applications for Treating Heart Disease - 6 Current Use Cases

Artificial Intelligence Applications for Treating Heart Disease - 6 Current Use Cases | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Heart disease is the leading cause of death in the United States and currently affects an estimated 28.4 million Americans. According to a report published by the American Heart Association, in 2016, the economic burden of cardiovascular diseases (category of heart and blood vessel diseases) totalled $555 billion and is projected to reach $1 trillion by 2035.

Compelled by these statistics, researchers are exploring how artificial intelligence could turn the tide and reduce incidences of heart disease.

To gain insight on the role of artificial intelligence in addressing heart disease, we researched this sector in depth to help answer questions business leaders are asking today, including:

What types of AI applications are currently in use to manage heart disease?
How has the market responded to these AI applications?
Are there any common trends among these innovation efforts – and how could these trends possibly contribute to reducing the rates of people living with heart disease?
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eHealth mHealth HealthTech innovations - Marketing Santé innovant
Digital, Apps, IoT, devices, AI / DL (...) innovations for Health and Healthcare
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Google AI algorithm to help with metastatic breast cancer diagnosis

Google AI algorithm to help with metastatic breast cancer diagnosis | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Google's artificial intelligence team has developed an algorithm that's like "spell check" for pathologists, the doctors responsible for diagnosing cancer patients through images of their cells.


In two papers published Friday, Google found that its algorithm complemented what the pathologists were able to pick up from the images in terms of determining how much patients' cancers had spread in their lymph node tissue.


"This represents a demonstration that people can work really well with AI algorithms than either one alone," Yun Liu, a member of the Google AI team and an author on the papers, told Business Insider.

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Santé et IA : les Gafa et les start-up dans la course

Santé et IA : les Gafa et les start-up dans la course | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

Les géants du Web s'intéressent de près à la santé, Google en tête, IBM n'est pas très loin, mais les start-up ont aussi leur carte à jouer.

Et si les Gafa devenaient aussi des géants de la santé ? Google a tenté d'enfiler la blouse blanche il y a plus de dix ans. Après l 'échec de Google Health , son dossier médical en ligne abandonné en 2012, la firme est revenue en force avec sa filiale DeepMind Health, en faisant ce qu'elle sait faire de mieux : collecter et traiter les données. En l'occurrence celles de patients d'hôpitaux, notamment britanniques.

Les choses ont toutefois été plus difficiles que prévu avec le Royal Free Hospital Trust, qui lui permettait d'accéder à l'historique médical de 1,6 million de patients. L'accord a été dénoncé quand les autorités britanniques ont constaté que ces données n'avaient pas été anonymisées et avaient été utilisées dans un cadre plus large que prévu.

Mais Alphabet, la maison mère de Google, a plusieurs fers au feu. Le projet Baseline, porté par sa filiale Verily, a l'ambition de « cartographier » la santé humaine, en recueillant les données de santé de 10.000 volontaires grâce à des objets connectés. Dernière initiative en date liée à la galaxie Alphabet, la start-up Cityblock, dans laquelle a investi une autre filiale, Sidewalk Labs, vise à offrir des services médicaux et à faire de la prévention en direction des titulaires des minima sociaux américains.

Les autres géants du Web ne sont pas inactifs. Amazon se lance dans l'assurance santé, et Facebook AI Research (Fair), après avoir recruté Yann LeCun, l'un des pères du « deep learning », a embauché en début d'année Jérôme Pesenti, un ancien responsable du programme Watson d'IBM. Apple confirme aussi son intérêt pour la santé avec sa montre Apple Watch Series 4, le premier appareil grand public doté d'un capteur et d'un algorithme susceptibles de détecter un incident cardiaque.

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Hennebont. Un robot innovant pour les victimes d’AVC

Hennebont. Un robot innovant pour les victimes d’AVC | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Répondant à un appel à projets « Innovation en santé » de l’Agence régionale de santé (ARS) de Bretagne, le robot Reaplan a trouvé preneur sur le sol breton. Acquisition du Groupe Hospitalier Bretagne Sud (GHBS), la machine a été inaugurée, vendredi. L’enjeu ? Optimiser la rééducation des patients victimes d’un accident vasculaire cérébral (AVC).

Grand écran, joystick : il pourrait ressembler à s’y méprendre à une nouvelle console de jeux vidéo haute technologie. Le robot s’adresse aux patients (adultes ou de pédiatrie) atteints de troubles neurologiques ou traumatologiques. Scratchs serrés, la main positionnée sur le joystick : le programme propose trois modes d’intensité (passif, actif aidé, actif) et variation de jeux (circuits à suivre, recettes virtuelles). Les gestes (calqués sur ceux du quotidien) sont relayés et enregistrés sur le superviseur, permettant d’analyser au plus juste l’évolution. « L’activité ? Environ 500 mouvements par séance, contre moins de 100 avec une séance traditionnelle. Plus on est dans l’intensité, plus le cerveau est stimulé pour créer un réseau de neurones », explique Fabien Nicolet,ergothérapeute. Si le robot est initialement voué aux patients victimes d’AVC, il se montre également efficace pour d’autres pathologies (type Parkinson, syndrome de Guillain-Barré). « C’est une matière grise qui évoluera une fois que l’on aura plus de recul. Elle a vocation à profiter au plus grand nombre », reconnaît Éric Hanesse, directeur de Axinesis, la start-up belge qui a mis au point le robot.
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eCAC40 : comment Sanofi  combine data et molécule, Transformation digitale

eCAC40 : comment Sanofi  combine data et molécule, Transformation digitale | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
« La santé de demain est une combinaison entre la data et la molécule », a lancé Guillaume Leroy, président-directeur général de Sanofi France lors de la cérémonie des Trophées eCac40, le 9 octobre dernier. De la recherche-développement au patient, en passant par les relations avec les médecins, Sanofi a pris le temps de définir là où les technologies pourront faire la différence. Engagée réellement depuis près de deux ans, sa transformation numérique se fonde sur sept piliers : les études cliniques digitales, la transformation du réseau industriel, les échanges multicanaux avec les médecins, le marketing digital, l'utilisation de données réelles, des solutions numériques allant au-delà du médicament et à destination des patients et des soins intégrés pour une gestion efficace du diabète.


Aller au-delà du simple médicament

Ces sept initiatives prioritaires vont créer de la valeur de deux manières : travailler plus vite et créer de nouveaux modèles commerciaux. « Notre objectif est de construire des solutions et un traitement des données les plus sécurisés possible pour tous nos patients », développe Heather Bell, SVP, global head of digital and analytics de Sanofi.

Pour mener à bien ces projets, le groupe s'est rapproché de géants de la tech comme Google, mais aussi de start-up. « Nous travaillons de manière ouverte depuis longtemps avec l'ensemble de l'écosystème technologique. Nous allons toujours à la rencontre de nouveaux acteurs de différents secteurs », confirme Heather Bell.


Entre réglementation et agilité

En janvier dernier, ils ont ouvert 39BIS, à la fois espace de rencontre avec l'écosystème santé et laboratoire d'innovation. « C'est un laboratoire entièrement dédié à l'e-santé », précise Guillaume Leroy. Plus de 500 personnes − collaborateurs de Sanofi, universitaires, et start-up − s'y retrouvent régulièrement pour chercher de nouvelles solutions à apporter aux patients. Face à ce succès, le groupe pharmaceutique a d'ailleurs lancé un autre centre d'innovation à Shangaï. Sanofi travaille et a investi notamment dans une start-up d'analyse comportementale et dans une jeune pousse californienne qui effectue des études cliniques distribuées : le patient peut participer en étant à son domicile, il n'a plus besoin d'être à l'hôpital. Ce qui élargit la population participant à l'étude.

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With $4.5B, Q3 2018 was digital health funding's biggest quarter yet  #hcsmeufr #esante #digitalhealth

With $4.5B, Q3 2018 was digital health funding's biggest quarter yet  #hcsmeufr #esante #digitalhealth | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

The third quarter of 2018 was the biggest funding quarter for digital health ever, according to StartUp Health Insights. The research group attached to healthcare startup alliance StartUp Health reported $4.5 billion in digital health funding.

With $11.1 billion invested so far, investment is only $600 million short of last year’s overall total, even including the fourth quarter.

The top five deals of the quarter were Peloton’s $550 million round, Oscar Health’s $375 million, Grail’s $300 million, 23andMe’s $300 million and American Well’s $290 million. The most active investors were Khosla Ventures with 13 deals, while Founders Fund, NEA and F Prime had 10 each.

 

Why it matters

In addition to the broad takeaway of more funding than ever, StartUp’s report also showcases some other interesting investment trends.

International digital health companies are raising more money, especially those based around Beijing, China, which saw $863 million raised and fostered five of the top 10 international deals. Three other Chinese cities, Zhenjiang, Shanghai and Hangzhou, did $100M or more in deals.


Via Florian Morandeau, Lionel Reichardt / le Pharmageek
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Florian Morandeau's curator insight, October 12, 1:54 AM

$4.5 billion in digital health funding for Q3 2018.

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Biometrics, Blockchain Markets Grow as Providers Seek Patient Data

Biometrics, Blockchain Markets Grow as Providers Seek Patient Data | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

Healthcare organizations taking on an increasing amount of financial risk are exploring new ways of identifying, tracking, and engaging with patients.

In order to maintain strong relationships with individuals while getting ahead of population-level risks, healthcare organizations are turning to innovative strategies, including blockchain, biometric technologies, and population health management tools, according to a new series of market reports.

Overall, the global healthcare information technology segment is predicted to be worth nearly half a trillion dollars by 2024, says Transparency Market Research.

Over the next six years, the segment will see a healthy 10.1 percent compound annual growth rate (CAGR), largely driven by the North American market as providers race to get ahead of chronic diseases and contain unsustainable spending.

Health systems are still actively seeking out the tools required to collect, store, and analyze massive amounts of data, the report says, and hospitals are likely to continue adopting health IT tools at an above-average rate throughout the reporting period.

In order to keep infrastructure development costs low, many of these organizations will be investing in cloud-based technologies, adds a separate report from Healthcare Intelligence Markets.

Cloud computing, which can reduce the need for large up-front investments in servers, security, and staffing, will only become more popular as health systems attempt to extract new insights from their big data assets.

The cloud computing market in healthcare is likely to see a CAGR of 15 percent or more until 2026, the report indicates, with organizations adopting private, public, and hybrid cloud storage solutions from leading vendors such as Dell, IBM, Iron Mountain, and VMWare.

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Medisafe Integrates with Apple Health Records to Prevent Drug-to-Drug Interactions

Medisafe Integrates with Apple Health Records to Prevent Drug-to-Drug Interactions | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Medisafe’s new life-saving integration with Apple Health Records, which just became available to consumers. Medisafe is a medication management app that helps prevent deadly drug-to-drug interactions as well as fending off thousands of health risks and preventable hospitalizations. With Health Records, Medisafe can surface medications from multiple providers, and people will have even more access to their medication records and knowledge of potential DDIs.

DDIs cause nearly 74,000 emergency room visits and 195,000 hospitalizations each year in the US. Close to 40 percent of the U.S. population receive prescriptions for four or more medications. Over a third of older adults in the U.S. regularly use 5 or more medications or supplements, and 15 percent are potentially at-risk for a major DDI.
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AI-powered women's health platform lands $12M in Series A extension round

AI-powered women's health platform lands $12M in Series A extension round | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
This morning Flo Health, an AI-enabled women's health platform, announced that it closed a $12 million Series A Extension funding round led by Mangrove Capital Partners, with participation from Flint Capital and Haxus. The company plans to use the new money for the startup’s next growth phase, as well as product improvement.

The Redwood City, California-based startup is focused on women’s health. It uses AI to personalize the platform and takes users' age, health goals and physical condition into consideration.

When the platform first launched in 2015 it focused specifically on predicting a user’s menstrual cycle. It now has tools for girls preparing for their first period as well as for women going through menopause.

Users can access a period and ovulation tracker, graphs about health and mood, daily health insights and birth control reminders. The tool also has a pregnancy and post-pregnancy mode that lets expecting and new moms see the development of their baby, according to the company. Flo also gives women trying to become pregnant tips on conceiving.
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Embleema met la blockchain au service de la pharmacovigilance  #hcsmeufr #esante

Embleema met la blockchain au service de la pharmacovigilance  #hcsmeufr #esante | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

La start-up Embleema a annoncé le 10 octobre le lancement d'un consortium de blockchain en santé pour collecter les données en vie réelle des patients et assurer notamment une meilleure pharmacovigilance, un projet qui sera soutenu par une campagne de financement en crypto-monnaie.

 

Depuis une dizaine d'années, la blockchain prend une place de plus en plus importante dans la galaxie numérique et après avoir conquis le monde de la finance, elle séduit désormais celui de la santé.

 

Pour rappel, la blockchain consiste à inscrire dans une chaîne de blocs informatiques inaltérable toute transaction d'un objet numérique, et à la faire approuver de façon traçable et décentralisée par l'ensemble des acteurs membres de la chaîne.

 

Avec son carnet de santé numérique PatientTruth, la start-up franco-américaine Embleema est en pointe sur le sujet (voir dépêche du 12 janvier 2018).

Elle vient aujourd'hui de lancer Embleema Health Network, un consortium autour de la blockchain en santé qui doit permettre de récupérer les données en vie réelle issues des dossiers médicaux des patients mais aussi de leurs objets connectés, afin qu'ils les partagent "volontairement" avec la recherche clinique pour vérifier l’efficacité des nouveaux médicaments et dispositifs médicaux.

 

Ce "réseau" porté par Embleema réunira notamment les laboratoires Pierre Fabre mais aussi "plusieurs autres laboratoires, des associations de patients, des organisations chargées de définir des standards et un spécialiste de la régulation: le Dr Vahan Simonyan, ancien responsable de la bio-informatique à la Food and Drug Administration (FDA) américaine, qui nous a rejoint", a détaillé Robert Chu, fondateur de la start-up, à TICpharma.

 

Les laboratoires Pierre Fabre participeront à la construction du réseau décentralisé de blockchain et mettront leurs serveurs à disposition pour stocker et partager des données en vie réelle des patients participants.


Via VAB Traductions, Lionel Reichardt / le Pharmageek
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The First FDA-approved Digital Pill — What It Means for Pharma

The First FDA-approved Digital Pill — What It Means for Pharma | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Last year, the U.S. Food and Drug Administration (FDA) approved what is perhaps the boldest use of digital technology in healthcare: a pill that is integrated with an ingestible sensor that captures information about whether the patient has complied with her medication regimen. A patient ingests the pill and it sends the data to a patch worn on her torso, which adds various physiologic measures. From there the information is wirelessly sent to a mobile phone app, allowing both the patient and her physician to track how the patient is using and responding to her medication.

L.E.K. Consulting believes that the FDA’s approval of Japan-based Otsuka Pharmaceutical’s Abilify MyCite for certain psychiatric conditions — a first for digital medicine — will be seen as a landmark in patient-centered care. Approximately 50% of patients do not adhere to their medication as prescribed, taking it sporadically or with contraindicated foods or medicines, and 20-30% of prescribed medications are never even picked up at a pharmacy. This nonadherence problem varies in acuity depending on the disease and the population that is affected. The cost of this waste runs into the billions of dollars in unused medication and, in addition, often more expensive medical care.

Bridging gaps in global healthcare

The benefits of digital medicine go beyond the saving of costs to the healthcare system. Over time, we believe that it can help solve three core problems — we call them gaps — bedeviling the development and the delivery of healthcare around the world.
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L'AP-HP vise "100.000 volontaires à terme" au sein de sa communauté en ligne de patients pour la recherche (ComPaRe)

L'AP-HP vise "100.000 volontaires à terme" au sein de sa communauté en ligne de patients pour la recherche (ComPaRe) | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Créée en 2017 par l'Assistance publique-hôpitaux de Paris (AP-HP), la communauté de patients pour la recherche (ComPaRe) permet à 7.256 patients volontaires de répondre à des questionnaires en ligne, sur une plateforme de l'AP-HP, pour leur permettre de "devenir des acteurs de la recherche", a expliqué le Pr Philippe Ravaud, directeur du centre d'épidémiologie clinique de l'Hôtel-Dieu et fondateur du projet ComPaRe.

Créée en 2017, "véritablement lancée" en janvier 2018, la communauté en ligne de patients pour la recherche de l'AP-HP a pour objectif "d'apporter, par la recherche clinique, les connaissances nécessaires à l'amélioration de la qualité de vie des patients et de la prise en charge de leur maladie chronique".

Concrètement, ce sont actuellement 7.256 patients atteints de maladie(s) chronique(s) qui acceptent de répondre à questionnaires "10-15 minutes" par mois "pour faire avancer la recherche". "Ce programme incite les malades à devenir des acteurs de la recherche, cette démarche est cruciale pour nous permettre de mieux orienter la recherche et de réduire les coûts", a expliqué le Pr Ravaud.

"La taille moyenne d'un essai clinique est estimée à 100 malades. Nous souhaitons changer ce modèle et rendre cela plus collaboratif donc nous combinons et traitons les données renseignées par le patient, celles issues des bases de l'assurance maladie (Sniiram), des entrepôts de données comme celui de l'AP-HP et à l'avenir nous allons également tenir compte des données collectées par les objets connectés des patients pour les mettre, elles aussi, à disposition de la recherche."
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Why Cyber-Criminals Are Attacking Healthcare -- And How To Stop Them

Why Cyber-Criminals Are Attacking Healthcare -- And How To Stop Them | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
The last five years has seen a surge of attacks on the healthcare industry, with the largest breaches impacting as many as 80 million people. In July this year, it was revealed that 150,000 NHS patients' data was shared over a three-year period following a major breach.

Over in the US, the 2015 cyber-attack on Anthem saw hackers steal 78.8 million patient records, claiming highly sensitive data, including names, social security numbers, home addresses and dates of birth.

Meanwhile, this year, hackers breached the Singapore government’s health database with a targeted cyber-attack, accessing the data of 1.5 million patients.

Healthcare organizations collect and store vast amounts of personal information, making them a major target for cyber-criminals. This valuable data can be used for identity theft, says Peter Carlisle, head of EMEA at cloud and data security company Thales eSecurity.“In the US, stolen personal health insurance information can be used by criminals to obtain expensive medical services, devices and prescription medications, as well as to fraudulently acquire government benefits like Medicare or Medicaid.”

Healthcare breaches are especially serious because personal data can, in some cases, mean the difference between life and death. For example, says Carlisle, it could cause medications to become mixed up – or people might fail to get treatment for conditions such as diabetes.

In countries including the UK, the healthcare sector is viewed as critical national infrastructure, alongside the water, electricity and transport networks. “This makes it an attractive target for those hackers wanting to cause chaos,” Carlisle says.
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Téléconsultation, télémédecine : Doctolib va-t-il encore tout rafler ?

Téléconsultation, télémédecine : Doctolib va-t-il encore tout rafler ? | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

Serions-nous à l’aube d’une nouvelle ère, celle de la télémédecine ? Depuis le 15 septembre, les consultations médicales à distance, avec des généralistes ou des spécialistes, peuvent être remboursées par la Sécu, aux mêmes tarifs que les consultations en face à face. Une solution, peut-être aux déserts médicaux. Mais aussi l’occasion pour certaines entreprises de créer un nouveau business.

Selon les règles édictées par l’assurance-maladie, les téléconsultations remboursées devront avoir lieu via une liaison vidéo “sécurisée” (à partir d’un ordinateur avec webcam, mais aussi d’un smartphone ou d’une tablette), et pour respecter le parcours de soins du patient, uniquement avec son médecin traitant. D’après la Sécu, des logiciels comme Skype et FaceTime seraient “assez sécurisés pour l’échange vidéo avec le patient”. On aimerait tellement croire une telle assertion.... A noter que pour l’instant, toutes les pathologies peuvent en théorie être l’objet d’une consultation à distance - peu importe si le médecin, ne pouvant effectuer de palpations, confond une appendicite avec une gastro-entérite, et expédie son patient ad patres.


Doctolib veut être partout, et “c’est logique”

Au-delà de ces enjeux( pourtant vitaux) vite expédiés par l’assurance-maladie, le remboursement des consultations à distance sont donc l’occasion rêvée pour tout un tas d’acteurs économiques de créer un nouveau marché. Pour l’instant, les téléconsultations en France ne représentent que 2 % des 300 millions de consultations effectuées tous les ans. Mais bientôt, elles devraient probablement se développer considérablement. Et pour cause : Doctolib, qui domine déjà le secteur des prises de rendez-vous médicaux en ligne, vient de profiter de l’aubaine pour se lancer dans la téléconsultation - lancement prévu en janvier 2019.

Comme l'explique Julien Méraud, directeur de la stratégie de Doctolib, la plateforme de prises de rendez-vous en ligne compte aujourd’hui dans ses rangs 60 000 professionnels de santé et 20 millions de visites chaque mois. “Le remboursement de la téléconsultation est effectif depuis le 15 septembre, sous des conditions qui sont les mêmes qu’une consultation physique ; et étant donné que notre activité, c’est de mettre en relation les professionnels de santé et les patients, il nous semblait logique d’offrir un outil de téléconsultation. Tout comme aujourd’hui, si l’on peut prendre rendez-vous en ligne avec un médecin, c’est principalement grâce à Doctolib, demain si l’on veut faire une téléconsultation (avec un professionnel de santé qu’on connaît déjà), il est logique que ce soit grâce à nous”. Logique implacable.

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2018: AI Is Surging In Drug Discovery Market

2018: AI Is Surging In Drug Discovery Market | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

The idea of using artificial intelligence (AI) to accelerate drug discovery process and boost a success rate of pharmaceutical research programs has inspired a surge of activity in this area over the last several years. In 2018, things are getting even “hotter” with the increase in the amount of partnerships, investments and other important events, summarized and grouped below into “mini-trends”.

1. Venture capital is pouring into AI-driven drug discovery startups

This year has been marked by an impressive number of fundraising deals among AI-driven drug discovery startups -- a clear indication of the “AI for drug discovery” space gaining some serious attractiveness for venture capitalists.

BenevolentAI

So far, a London-based BenevolentAI appears to be a leader of the year in terms of fundraising -- in April they closed a $115 M round, reaching a staggering $2 billion valuation mark. While met with certain degree of skepticism, this news and the current pace of research activity by the company undoubtedly puts BenevolentAI in a very strong position among competitors.

Atomwise

Atomwise, which was founded in 2012 and pioneered the use of deep neural networks for structure-based drug design, raised $45 M round A investment to advance its AI-driven drug discovery technology AtomNet. The company says it screens 10 million small molecules each day and uses AtomNet, which is utilizing deep learning algorithms, to analyze molecules and predict their potency as medications, toxicity, and side effects.

Insilico Medicine

A quite unique company on the list -- a US-based Insilico Medicine, which is the only one startup among its closest competitors which develops a “full-stack” artificial intelligence system based on generative adversarial networks (GANs), allowing for an “end-to-end” drug discovery process -- from basic biological modeling and biomarker development, to hit-molecule generation, lead optimization and pre-clinical validation of drug-candidates. In June, Insilico Medicine received an undisclosed amount of strategic investment from WuXi AppTec, bringing totally raised capital up to $20 M (according to Crunchbase).

Verge Genomics

Notably, just a month later, WuXi AppTec participated in a $32 M investment round for another AI-driven startup -- Verge Genomics. The latter uses machine learning and AI to develop therapeutics against Alzheimer's and Parkinson’s disease. Verge is also actively growing its database of patient genomic data -- allegedly, the company possesses one of the industry’s largest resources in this therapeutic area.

Owkin

New York - Paris based Owkin, founded in 2016 to apply machine learning for optimizing drug discovery process via better comprehending the overabundant biological data, raised its Round A of $11M in January to scale its technology platform Owkin Socrates. The platform can integrate molecular and imaging libraries with patient data to reveal patterns of biomarkers causing a disease, and the company is applying transfer learning to improve model performance where properly labeled data is scarce.

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Data security concerns could be delaying smart inhaler rollout

Data security concerns could be delaying smart inhaler rollout | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
‘Smart’ or ‘connected’ inhalers are enhanced with the ability to collect and share data about their usage. A number of early players are already on the market and early trials across the globe are indicating that this can be an effective way of improving adherence.

Current smart inhalers enable patients and their healthcare provider to monitor how closely the prescribed treatment plan is being followed. As the sector matures, increased functionality, such as which parameters can be measured, is expected to follow. For example, devices that use acoustic sensors to monitor inhalation technique and provide feedback are already in development.

Michael Earl, Commercial Director at Bespak said, “Data shows that nearly all patients don’t always use their inhalers properly, and nearly two-thirds don’t always take their medication. Clearly there is a need to make inhalers more user-friendly to allow for better disease management. We know that increasing adherence to respiratory medication can more than halve hospital admissions. The cost saving implications and potential patient benefits are huge.”

Bespak has uncovered that 48% of chronic obstructive pulmonary disease (COPD) patients feel that device connectivity would have the most benefit if it could help in predicting exacerbations. Among professionals in the industry, improved patient engagement (44%) and improved health informatics (34%) are thought to be the areas where the technology can add the most value. 67% of industry participants in the research felt that connectivity would help with compliance of treatment regimes.

However, Bespak’s research revealed that despite 63% of the chronic COPD patients surveyed believing that connectivity would help in preventing the worsening of their respiratory condition, 59% voiced that they would not want a connected device. So why the apparent disconnect? Further questioning identified that security topped the list of concerns for many patients (59%), suggesting that a fear of data hacking has spread over from other industries.
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Aetna, CVS, Walgreens And Amazon May Finally Let Pharma Do What It Does Best

Aetna, CVS, Walgreens And Amazon May Finally Let Pharma Do What It Does Best | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Aetna, CVS, Walgreens, and Amazon are some of the most powerful words in healthcare. And in that context, the era of retail medicine is fast approaching. Much of this concept is build around the love affair with the customer that defines much of the retail marketplace today. Or, as some say, customer-centricity.

Today, there's a vast debate around the criticality of focusing on the customer and the emerging role of mega-companies such as Amazon and the newly government-approved merger of Aetna and CVS. Both are hot topics that seem to homogenize into the new healthcare dynamic that most seem to put forward as the " big idea" that will change the game.

Focus on the customer. Redefine the experience along the lines of the Apple store or The Four Seasons.

It all makes sense. The new role of "whatever-centricity" allows for a broken system to build things from the customer and move upward. With that newfound focus, we can reinvent healthcare by learning from the "business physicians of the day" like Steve Jobs, Warren Buffet, and Jeff Bezos. The democratization of healthcare is getting closer.

But there's another player in this complex set of moving parts that is hovering over these changes with a watchful and worried eye: the pharmaceutical industry. Seeking to reinvent itself too, big pharma has been quick to adopt the patient first strategy and proudly displays its perspective in just about every mission statement and tagline around. But pharma's nervous preoccupation with patient-centricity and its potential collision course with the retail giants may be the best thing that ever happened to this industry.

Big pharma and the even bigger retail giants appear to be moving to battle. The financial forces, the PBMs, the vocal consumers, and the marketing departments appear to align for the battle of healthcare. Most conversations seem to establish a zero-sum game where there will be a winner and a looser.
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FDA Clears First App-Only Product for Detecting Atrial Fibrillation 

FDA Clears First App-Only Product for Detecting Atrial Fibrillation  | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

FibriCheck, a Belgian firm, won FDA clearance for its smartphone application that is capable of spotting signs of atrial fibrillation, simply by using the phone’s camera. The user places a finger over the camera lens on the back of the phone and initiates the app to do its thing. The app utilizes photoplethysmography to optically watch for changes of the vessels within the finger as blood pumps through with each beat. A regular rhythm within normal speeds indicates a healthy heart, while missed beats or an irregularly irregular rhythm may signal the presence of an underlying condition.


Via Lionel Reichardt / le Pharmageek
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Pharma, Life Science Leaders Face Big Data Analytics Challenges

Pharma, Life Science Leaders Face Big Data Analytics Challenges | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

Pharmaceutical and life science companies are staring down major challenges as value-based care alters the healthcare landscape, but those that are further along in their digital transformations are also more likely to embrace innovation and creative thinking about common business problems, according to a new survey by Deloitte and MIT.

Organizations that have more mature big data analytics and digital engagement skills are tend to have leaders that embrace change and staff members who are willing to get on board with new initiatives, positioning them well for exponential growth.

However, many organizations are failing to translate their recognition of the need for digital strategies into real-world adoption, leaving them at risk of falling behind their peers in a highly competitive environment.

“Biopharma leaders know that if they don't embrace digital transformation they will be surpassed by more agile competitors,” said Greg Reh, principal, Deloitte Consulting LLP, and US and global life sciences leader.

“But transformation can pose some cultural challenges that slow the pace of change. The good news is that their mindsets are shifting toward greater digital experimentation, collaboration, and innovation.”

The international survey of biopharma leaders revealed that more than 75 percent of companies are still in the early phases of digital development, with 25 percent placing themselves on the lowest rung of adoption and 55 percent stating that they are “developing their capabilities.”

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Novartis launches digital health innovation lab the Novartis Biome

Novartis launches digital health innovation lab the Novartis Biome | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Novartis has launched a digital health innovation lab network named the Novartis Biome to accelerate its digital evolution.

The Swiss pharma company will also run a series of open innovation initiatives it says are designed to provide an ‘on-ramp’ for start-ups that wish to work with it.

The Novartis Biome, whose first digital health innovation lab is based in San Francisco, has been co-founded by its head Mohanad Fors, head of open innovation Shwen Gwee and head of innovation and strategy Robin Roberts.

Novartis Biome Robin RobertsRoberts (pictured) said: “The idea is to give the health tech ecosystem a boost and clear ‘on-ramp’ to work with Novartis.

“It’s clear to anyone who works in digital health that the vast majority of disruptive technologies are not going to come from big pharma companies. But we can engage and work with startups and innovators, and together make something bold, sustainable and scalable.”

The company hopes to fill what it sees as a gap in the current ecosystem, whereby “nascent technologies are not typically supported and shaped by the companies that can ultimately harness them”.

The Novartis Biome by proactively scouting for technology, seeking referrals and issuing challenges through an initiative called the HealthX World Series. The first of this series of global, open innovation challenges took place last month in San Francisco at TechCrunch Disrupt SF.
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From Flintstones to the full-stack: How precision care and consumerization will modernize healthcare delivery

From Flintstones to the full-stack: How precision care and consumerization will modernize healthcare delivery | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

There is tremendous innovation in cancer research these days, which was recognized just last week with the Nobel Prize in Medicine awarded to two pioneers of immunotherapy.

This inevitably begs the question, what’s next? It’s a good time to take a step back from the day-to-day changes in cancer care and take stock of the disruptive trends pushing the broader healthcare system — and therefore cancer care — forward over the next five years.

Before we examine the future though, let’s start with the reality of today. Today, we have precision medicine without a precision care delivery system. The advance in molecular understanding of disease and immunology, the ubiquitous availability of DNA sequencing, and unheralded investment into scientific research have led to an explosion in scientific innovation and new treatment paradigms such as immunotherapy, CAR-T, and gene therapy. Yet the day-to-day delivery of patient care remains largely unchanged and even somewhat medieval. When I was at the White House Frontiers Conference in 2016, Pfizer’s Chief Medical Officer Freda Lewis-Hall memorably put it best: “We have Star Wars medicine in a Flintstones healthcare system.”

From manufacturing to transportation, technology-enabled solutions have helped countless industries deliver higher quality at lower costs. In healthcare, this is called “value-based care.” Healthcare delivery, however, has not had labor productivity gains and is more often technology-disabled than technology-enabled. For a three trillion dollar industry and with millions of patient lives at stake, this is a major problem both to our economy and our health.

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Forces Driving The Growth Of Wearable Medical Device Market

Forces Driving The Growth Of Wearable Medical Device Market | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Grand View Research, a U.S. based market research and consulting company, reported that the wearable medical device market is estimated to be worth USD 58.3 billion by 2025.

Wearable technology in healthcare is predominantly used for monitoring and diagnostic purposes. These devices are based on ecosystem in which various components are interconnected to each other for real time functioning. Components include hardware and software both and can be categorized into wearable device component, communication interface, and companion device interface. The information is exchanged between wearable device and companion device through the communication interface. The upcoming therapeutic technologies include intelligent asthma management, backache & pain relief devices, and smart contact lenses. For instance, intelligent asthma management by Health Care Originals Inc., is currently in the development phase and this device gives alerts when patient is experiencing asthma situation.

The wearable medical device market is segmented based on product, application, site and region.
Factors affecting the market growth are as follows:

Rising demand for round the clock monitoring
Growing awareness on fitness
Advent of technologically advanced products
Rising per capita income
Non-availability of reimbursement
Data security and privacy issues
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Hôpital Henri-Mondor, AP-HP : une équipe publie pour la première fois une classification des dispositifs de réalité augmentée en chirurgie maxillofaciale

Hôpital Henri-Mondor, AP-HP : une équipe publie pour la première fois une classification des dispositifs de réalité augmentée en chirurgie maxillofaciale | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
Depuis plusieurs années, les chirurgiens ont recours à la réalité augmentée en chirurgie maxillofaciale et cranofaciale avec notamment le port de lunettes intelligentes. L’équipe du service de chrirugie plastique, reconstructrice, esthétique et maxillofaciale de l’hôpital Henri-Mondor, AP-HP a analysé la littérature et vient de catégoriser les différentes techniques utilisées dans ce domaine. Cette étude est publiée dans la revue International Journal of Oral & Maxillofacial Surgery le 11 octobre 2018. En plus de libérer le champ visuel et les mains du chirurgien, la réalité augmentée constitue dans ce domaine une avancée majeure. L’équipe l’utilise également pour le repérage précis des tumeurs mammaires.

La réalité augmentée sur lunettes intelligentes permet au chirurgien de visualiser des objets virtuels en trois dimensions pendant l’intervention chirurgicale, superposés en temps réel à l'anatomie du patient. Elle est utilisée en radiologie, en radiologie interventionnelle, en neurochirurgie, en ORL, parfois en chirurgie cœlioscopique digestive ou urologique. L'objectif de cette nouvelle étude, menée par le Dr Romain Bosc du service de chirurgie plastique, reconstructrice, esthétique et maxillofaciale dirigé par le Pr Jean Paul Meningaud, dans la continuité des études précédemment publiées par la même équipe[1], est de délimiter le champ d'application actuel de cette technologie.
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HIMSS Analytics delivers a state of the health IT industry report #hcsmeufr #esante

HIMSS Analytics delivers a state of the health IT industry report #hcsmeufr #esante | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

The research firm examines where EHRs, cloud, blockchain, telehealth, security and other technologies are today – and where they might be headed.

 

For National Health IT Week 2018, HIMSS Analytics delivered new research exploring some key trends, looking closely at established software infrastructure and emerging technologies alike.

 

"What we're seeing as far as a state of the market is acceleration beyond the EMR," said Blain Newton, executive vice president of HIMSS Analytics. "We're seeing it manifest in a few different ways."

 

Those post-EHR technologies and trends include blockchain, cloud computing, security, precision medicine, supply chain, telehealth and, of course, network infrastructure. 

 

Electronic health records. EHRs are a key piece of the health IT infrastructure and the market segment is very mature with near universal adoption, according to HIMSS Analytics data – but only 2 percent of hospitals have a single vendor enterprise EHR.

 

Instead, the average system has 15 vendors across its affiliates — making the next issue a complex mess. "We're seeing migration past the EMR as a foundation as well as retrofitting how we create scale and secure infrastructure," Newton said.

 

Interoperability. With mega-mergers such as Dignity and CHI and CVS Health and Aetna – as well as Amazon's partnership with JPMorgan Chase and Berkshire Hathaway – significant challenges are arising amid the hodgepodge of EHR vendors.

 

"Creating a secure environment where interoperability can happen is not a challenge of desire," said Newton. "It's very technical."

 

Telehealth. Whereas the U.S. has surpassed a 50 percent adoption rate for telehealth capabilities, the average hospital has upwards of five different products installed, meaning it has yet to widely reach enterprise-level deployments. The surprise HIMSS Analytics found in its data is that the highest adoption levels for telemedicine tools are among non-profit hospitals with 100 beds or fewer.

 

"For a technology that the ROI is not yet entirely clear, you're seeing nonprofits with a very significant lead in adoption, presumably to reach out to rural populations," said Newton. "Either way, it's an unexpected view, we thought it would be large hospitals." When asked whether they plan to invest in telehealth in the next two years, 27 percent said yes, 18 percent said no and 55 percent said they weren't sure.

 

Precision medicine. In contrast to EHRs' near-ubiquity and telehealth on the rise, precision medicine adoption today is limited. The top three reasons are a lack of funds, technologies, and the clinical expertise necessary to undertake such programs. That said, 45 percent of respondents to HIMSS Analytics research said they plan to expand precision medicine work, while 23 percent do not and 32 percent are unsure.

 

Security. This should come as no surprise, but Newton said that "healthcare is absolutely a target," for nefarious attacks as 29 percent of breaches last year hit healthcare, a higher rate than any other industry.

 

"Twelve percent of hospitals do not have basic IT security systems," Newton said. "That's a bit frightening because whether you're the Mayo Clinic or a rural provider in south Dakota, you're a target." Protecting health data is one of the reasons more hospitals are looking to the cloud. But it's not the only one.

 

Cloud computing. Sixty-five percent of hospitals currently use cloud services in some capacity, and Newton said that it's expected the majority of EMRs will be cloud-based by 2020. Among the reasons healthcare organizations move to the cloud: 37 percent said it's for disaster recovery, while 25 percent said the cloud lowers current IT maintenance costs, another 25 percent answered that it'd sue to a lack of on-site IT staff or expertise and 13 percent do so to meet the need for a scalable always-on app or service.

 

"There's a significant component just looking at baseline IT costs, regardless of the motivator, the cloud is coming, on-premise is a thing of the past," he said. "It has really shifted wholesale here because of efficiencies and levels of service. I would expect this to continue increasing." 

 

Blockchain. Blockchain is still in the hype stage, to be certain, though it also appears that some early days type of activities are happening with 50 percent of health org's either investigating or building a business case around Blockchain, and doing so with plans to run a proof of concept in the next 24 months.

 

But payers, pharma and tech vendors are moving more quickly than healthcare providers, which may be hanging back to let the others figure it out first. Non-providers, in fact, are twice as likely as providers to conduct a proof of concept or pilot in the next two years.

 

Patient-generated health data. This was another surprising finding. "Organization said they are at least moderately prepared for consumer-generated data," said Newton. While more than 80 percent of patients are already expecting to see data in their record, in fact, 67 percent of hospitals are looking to invest. Just don't expect it to happen quickly.

 

"When we talk to CIOs, they flat out said this is an issue of data governance," he explained. "We don't believe we have adequate governance in place to manage consumer generated data."

 

Supply chain. Acknowledging that a better name for supply chain in this context might be utilization management and resource stewardship, Newton described it as "one of the biggest things we see happening."

 

Four of the top 10 predictive technologies are supply chain management related and hospitals should proactively invest in clinical infrastructure for tools that alert clinicians to risk or enable traceability that helps determine which products or people are safest and most cost-effective, as well as technology to enable learning systems.

 

"I see this as becoming something significant over the next 18 months or so and becoming much more enterprise focused as folks look to drive down costs and improve care," he added. "We see this as a powerful new capability that organizations are looking to go after."


Via VAB Traductions, Lionel Reichardt / le Pharmageek
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mHealth platforms are helping healthcare providers with Quick Access to Decision Support Resources  #hcsmeufr #esante #digitalhealth

mHealth platforms are helping healthcare providers with Quick Access to Decision Support Resources  #hcsmeufr #esante #digitalhealth | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it

Healthcare providers who access clinical decision support through mHealth platforms are finding a world of information at their fingertips – and they could be saving lives.

 

Digital technologies are changing the way medical information is gathered and exchanged.  Physicians of all ages and medical subspecialties from across the globe are utilizing tools to discuss potential diagnoses and obtain second opinions.

 

That’s the takeaway from researchers at the Scripps Research Translational Institute who took a closer look at online crowdsourced consult platforms.

 

Their conclusion is that these platforms, which include social media networks like SERMO, Medscape and HealthTap, are giving providers quick access to information that’s helping them reduce serious, costly and potentially deadly medical errors.

 

The study, focusing on an analysis of more than 37,000 active users on the MedScape Consult network between 2015 and 2017, appears in a recent issue of NPJ Digital Medicine.

 

The research points to the value of a mobile health resource for clinical decision support, giving providers a real-time portal for physician-to-physician engagement. Billed as a source for “the second to hundredth opinion in medicine,” these portals allow providers to gather best practices and apply them quickly, reducing the chances of a clinical error.

 

The study also points to the changing nature of clinical decision support.The study noted that providers can’t necessarily rely on informal face-to-face consults with colleagues – commonly known as curbside consults – because they’re “frequently inaccurate and incomplete.” Yet they can’t just call up a nearby specialist at a moment’s notice.

 

The study found that : "At a time when we’re turning to artificial intelligence to help improve diagnostic accuracy, there’s still plenty of room for tapping into human intelligence via such medical consulting platforms, Artificial intelligence has been advocated as the definitive pathway for reducing misdiagnosis, But the study's findings suggest the potential for collective human intelligence, which is algorithm-free and performed rapidly on a voluntary basis, to emerge as a competitive or complementary strategy."

 

 


Via nrip, Lionel Reichardt / le Pharmageek
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nrip's curator insight, October 11, 12:38 AM

Well how surprising! Collective human intelligence still works :)

 

For us, its not surprising. As I been posting in my articles, speaking at my talks and offering my $0.02 in my insights,  for all the talk of AI and Deep Learning, I feel technology's best use in healthcare is in automation of processes and improving communication and collaboration.  And such studies show that we have lots of gain by building better tools to help clinicians communicate and collaborate better. Someday , AI "may" replace human intelligence, but not today and not anytime soon.

 

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» Télémédecine : CardioRenal et le CEA signent un partenariat pour perfectionner leur dispositif

» Télémédecine : CardioRenal et le CEA signent un partenariat pour perfectionner leur dispositif | eHealth mHealth HealthTech innovations - Marketing Santé innovant | Scoop.it
CardioRenal a signé cet été un accord de co-développement avec le CEA. Cet accord portant sur plusieurs années permet à CardioRenal de bénéficier de l’expérience et des infrastructures du CEA pour poursuivre le développement de capteurs incorporant les technologies d’électrochimie et de microfluidique de dernière génération afin d’accélérer la commercialisation d’un véritable laboratoire d’analyse de sang utilisable à domicile par les patients insuffisants cardiaques.

L’insuffisance cardiaque est la première cause d’hospitalisation chez l’adulte dans les pays développés. CardioRenal a conçu un dispositif de télémédecine qui permet un suivi de paramètres biologiques des patients à domicile dans le but de leur éviter des hospitalisations traumatisantes et coûteuses pour les systèmes de santé.

Le CEA et CardioRenal mettront au point les évolutions des capteurs électrochimiques inclus dans la puce microfluidique qui fait les mesures des paramètres biologiques dans une goutte de sang du patient.

Après l’accord de co-développement et de licence noué mi-2017 avec la division WeHealth by Servier, CardioRenal continue ainsi de s’entourer de partenaires de réputation internationale afin de devenir un acteur incontournable de la télémédecine. Outre l’appui R&D des équipes du CEA, cet accord permettra à CardioRenal de bénéficier de l’appui de Hub4AIM, alliance de partenaires académiques et industriels dotés des compétences nécessaires à toute la pré-industrialisation des dispositifs médicaux innovants.
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