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Is Marijuana the Next Diabetes Drug?

Is Marijuana the Next Diabetes Drug? | Diabetes News on MediPlanet | Scoop.it
Is Marijuana the Next Diabetes Drug? http://t.co/pBzw0b4TPo
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A New Old Diabetes and Obesity Drug Candidate - Corante

A New Old Diabetes and Obesity Drug Candidate - Corante | Diabetes News on MediPlanet | Scoop.it
A New Old Diabetes and Obesity Drug Candidate Corante Obesity is a therapeutic area that has broken a lot of hearts (and wallets) over the years. A scroll back through this category will show some of the wreckage, and there's plenty more out there.
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Permanent stress can cause type 2 diabetes in men

Permanent stress can cause type 2 diabetes in men | Diabetes News on MediPlanet | Scoop.it
Men who reported permanent stress have a significantly higher risk of developing type 2 diabetes than men who reported no stress.

Via Jane Young
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Change in HbA(1c) over 3 years does not improve the prediction of cardiovascular disease over and above HbA(1c) measured at a single time point.

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Change in HbA(1c) over 3 years does not improve the prediction of cardiovascular disease over and above HbA(1c) measured at a single time point.
Diabetologia.
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The impact of metabolic control and QTc prolongation on all-cause mortality in patients with type 2 diabetes and foot ulcers.

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The impact of metabolic control and QTc prolongation on all-cause mortality in patients with type 2 diabetes and foot ulcers.
Diabetologia.
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10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes

10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes | Diabetes News on MediPlanet | Scoop.it

During the United Kingdom Prospective Diabetes Study (UKPDS), patients with type 2 diabetes mellitus who received intensive glucose therapy had a lower risk of microvascular complications than did those receiving conventional dietary therapy. We conducted post-trial monitoring to determine whether this improved glucose control persisted and whether such therapy had a long-term effect on macrovascular outcomes.

Results Between-group differences in glycated hemoglobin levels were lost after the first year. In the sulfonylurea–insulin group, relative reductions in risk persisted at 10 years for any diabetes-related end point (9%, P=0.04) and microvascular disease (24%, P=0.001), and risk reductions for myocardial infarction (15%, P=0.01) and death from any cause (13%, P=0.007) emerged over time, as more events occurred. In the metformin group, significant risk reductions persisted for any diabetes-related end point (21%, P=0.01), myocardial infarction (33%, P=0.005), and death from any cause (27%, P=0.002).

Conclusions

Despite an early loss of glycemic differences, a continued reduction in microvascular risk and emergent risk reductions for myocardial infarction and death from any cause were observed during 10 years of post-trial follow-up. A continued benefit after metformin therapy was evident among overweight patients. (UKPDS 80; Current Controlled Trials number.


Via Seth Bilazarian, MD
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Seth Bilazarian, MD's curator insight, October 8, 2013 9:36 AM

Amazing! Twenty five years ago the UKPDS published the follow-up of metformin in diabetes showing a benefit on heart attack and death even years after patients came off the drug.  Despite years of basic science and clinical research and billions of dollars spent on development of new therapies we still don't have a single other diabetes drug that reduces heart attack risk. Many drugs have been developed for blood sugar control but all have shown no benefit over placebo for reduction of heart attack risk for diabetics.  Only metformin.

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Mediterranean diet may be best for diabetes

Diets lean on meat and rich in healthy fats like olive oil were most effective at promoting weight loss and lowering blood sugar among people with diabetes in a review of evidence from the last 10 years.

Benefits were also seen with diets low in carbohydrates, high in protein or low in simple sugars.

 

 


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Steve Kingsley's curator insight, June 2, 2013 1:32 PM

It certainly is the healthiest!

Steve Kingsley's curator insight, June 2, 2013 1:33 PM

It certainly is the healthiest!

Vincent D'Antonio's curator insight, June 10, 2013 9:09 AM

Diet based on a healthy region of the world.

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Asthma drug reverses obesity and diabetes in mice

Asthma drug reverses obesity and diabetes in mice | Diabetes News on MediPlanet | Scoop.it

Researchers at the University of Michigan’s Life Sciences Institute have found that amlexanox, an off-patent drug used to treat asthma and canker sores, can also reduce obesity, diabetes and fatty liver disease in mice.

 

 


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'High-glycemic' foods tied to diabetes risk - Fox News

'High-glycemic' foods tied to diabetes risk - Fox News | Diabetes News on MediPlanet | Scoop.it
'High-glycemic' foods tied to diabetes risk
Fox News
According to the U.S. Centers for Disease Control and Prevention, about 8 percent of Americans have diabetes.
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