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Important news for those concerned with all types of diabetes, associated autoimmune diseases, & health
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Charlottetown boy heading for World Diabetes Cup - Prince Edward Island - CBC News

Charlottetown boy heading for World Diabetes Cup - Prince Edward Island - CBC News | diabetes and more | Scoop.it
A 12-year-old boy from Charlottetown is out to prove his disease cannot define what he can do.
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Parents: Day Care Won't Give Insulin Shots

Parents: Day Care Won't Give Insulin Shots | diabetes and more | Scoop.it
The parents of a two-year-old girl with diabetes claim a Coppell day care is violating the law because it refuses to give her insulin shots.
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ACCU-CHEK Bluetooth-Powered Blood Glucose Meter Insulin Pump Combo System Receives FDA Approval

ACCU-CHEK Bluetooth-Powered Blood Glucose Meter Insulin Pump Combo System Receives FDA Approval | diabetes and more | Scoop.it
Roche has received FDA clearance for its Accu-Chek Combo system for insulin pump therapy.
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Evaluation of a portable ambulatory prototype for automated overnight closed-loop insulin delivery in young people with type 1 diabetes - Elleri - 2012 - Pediatric Diabetes - Wiley Online Library

Evaluation of a portable ambulatory prototype for automated overnight closed-loop insulin delivery in young people with type 1 diabetes - Elleri - 2012 - Pediatric Diabetes - Wiley Online Library | diabetes and more | Scoop.it
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Kaiser and Other Health Systems Create Nation’s Largest Private-Sector Diabetes Registry | Dark Daily

Kaiser and Other Health Systems Create Nation’s Largest Private-Sector Diabetes Registry | Dark Daily | diabetes and more | Scoop.it
New database of diabetes patients opens door for pathologists to improve existing medical laboratory testing algorithms

Integration of healthcare informatics is proceeding at a brisk pace. The latest evidence comes from 11 highly-respected integrated health systems that are pooling data to create the largest, most comprehensive private-sector diabetes registry in the country. It will contain information from 1.1 million diabetic patients.

 

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Trial Data: ALV003 Reduces Gluten Damage in Celiac Disease Patients - Celiac.com

Trial Data: ALV003 Reduces Gluten Damage in Celiac Disease Patients - Celiac.com | diabetes and more | Scoop.it
Celiac.comTrial Data: ALV003 Reduces Gluten Damage in Celiac Disease PatientsCeliac.comCeliac.com 07/23/2012 - At 2012 Digestive Diseases Week in San Diego, California, Alvine Pharmaceuticals, Inc.
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Braving crowds, waiting for hours for free medicine

Braving crowds, waiting for hours for free medicine | diabetes and more | Scoop.it
For Ramaiyah Venkat, a retired Indian schoolteacher, the two-hour bus journey every three months to get free insulin is worth it even if he has to queue for hours at the dispensary and sometimes gets less than he needs.
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Access to insulin pump therapy and continuous glucose monitoring – is it an even playing field? - Hitman - 2012 - Diabetic Medicine - Wiley Online Library

Access to insulin pump therapy and continuous glucose monitoring – is it an even playing field? - Hitman - 2012 - Diabetic Medicine - Wiley Online Library | diabetes and more | Scoop.it

Some patients with Type 1 diabetes do not want to use an insulin pump, but would consider the use of a continuous glucose monitoring system (CGMS). Unfortunately, there is no formal guidance on this issue in many countries, which makes it even more difficult for this to be considered an option, despite the wishes of those living with diabetes and health professionals advising on best practice.

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Detection of hypoglycemia associated... [Diabetes Res Clin Pract. 2012] - PubMed - NCBI

CONCLUSIONS:
Continuous EEG monitoring and automated real-time analysis may constitute a novel technique for a hypoglycemia alarm in patients with IAH.

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Little Ellie, 10, embracing life as she's losing sight and hearing to incurable rare disease in the next few months

Little Ellie, 10, embracing life as she's losing sight and hearing to incurable rare disease in the next few months | diabetes and more | Scoop.it

PLEASE SUPPORT A CURE FOR WOLFRAM SYNDROME.

 

Ellie White, 10, of Colorado, has been diagnosed three years ago with a rare genetic illness that will soon leave her blind and deaf, but before that happens, the little girl is determined to live life to the fullest.

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West Seattle Blog… » Rylee’s Pocket: West Seattleites create a shirt for diabetic kids – and need your help to donate dozens

West Seattle Blog… » Rylee’s Pocket: West Seattleites create a shirt for diabetic kids – and need your help to donate dozens | diabetes and more | Scoop.it
Sarah Syvertsen of Arbor Heights e-mailed WSB to share the news about her brand-new business, Rylee’s Pocket. She and her aunt are “making tank tops for kids and adults with type 1 diabetes that have a special pocket to hold their insulin pumps.
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Joslin Diabetes Center Convenes Leaders in Diabetes Prevention, Treatment, Payment, Education and Research at Diabetes Innovation 2012

Not Just a Conference - A Call to Action
BOSTON, July 18, 2012 /PRNewswire/ -- The diabetes epidemic demands a powerful response from leaders in the diabetes community, nationally and globally. To this end, for the first time in its 114 year history, Joslin Diabetes Center, an affiliate of Harvard Medical School will convene all stakeholders for a groundbreaking, immersive activity over 3 days in September called Diabetes Innovation 2012 (September 23-25, 2012 at the Hyatt Crystal City in Arlington, VA).
Diabetes Innovation 2012 will act as a powerful catalyst for ideas, partnerships and collaborations. It will provoke thought, innovation and action that address the cost, productivity and quality-of-life impact of diabetes on our society by bringing together all stakeholders: payers, purchasers, providers, industry, government, research, patients, consumers, technologists, developers, and funders.
"Simply put, we MUST forge new approaches and dramatically increase our sense of urgency to address diabetes head-on. Despite all of our collective efforts, we are not keeping up with the global threats presented by obesity and diabetes," says John L. Brooks III, CEO, Joslin Diabetes Center. "To effectively make a real difference, we need to convene, apply our collective energies, and work together, to truly create innovative policies and programs that will involve all stakeholders and that will make a real difference. This world-wide pandemic will not be solved until all of us use our combined resources, commitment, determination, and passion to map out an aggressive and meaningful path forward."

 

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MissyFoy.com :The only diabetic runner ever to qualify for Olympic Marathon Trials, s

MissyFoy.com :The only diabetic runner ever to qualify for Olympic Marathon Trials, s | diabetes and more | Scoop.it
Meet Missy Foy! Missy is an elite marathon runner . . . and she has diabetes.
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delivering insulin in a skin cream | Chemistry World

Scientists in Japan have developed a way to administer insulin to patients through the skin. Such a method avoids one of the problems associated with injections and oral administration in which a drug’s concentration is reduced as it passes through the digestive system. It would also be a more pleasant experience for patients.
Masahiro Goto from Kyushu University in Fukuoka and SO Pharmaceutical Corporation in Kobe, and colleagues, prepared a capsule loaded with insulin that is able to penetrate the skin with its cargo.

The team made their capsule by surrounding insulin molecules with proteins and coating the protein molecules with a hydrophobic surfactant to from protein–surfactant complexes. Then, they added oligo-arginine peptides as protein transduction domains and dispersed the complexes in oil – isopropyl myristate – which is known to have a permeation-enhancing effect. ‘The main function of this new system is to promote protein penetration through the hydrophobic stratum corneum [outermost layer of the skin],’ explains Goto.

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Medtronic Announces 2012 Global Heroes

MINNEAPOLIS - July 23, 2012- Twenty-five long-distance runners who benefit from medical technology will be honored as "Medtronic Global Heroes" when they run the Medtronic Twin Cities Marathon or Medtronic TC 10 Mile on Sunday, October 7, 2012.

This year's team includes 10 international runners, the most in the program's seven-year history. Countries represented include: Australia, Austria, Brazil, Canada, Israel, Norway, South Africa, Spain and the United States. Each runner has a medical device to treat conditions such as heart disease, diabetes, spinal disorders, chronic pain or neurological disorders. The Medtronic Global Heroes program, launched in 2006, celebrates their accomplishments and passion for running, which serves as an inspiration to others living with chronic diseases.

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A diabetes awareness campaign prevents diabetic ketoacidosis in children at their initial presentation with type 1 diabetes - King - 2012 - Pediatric Diabetes - Wiley Online Library

A diabetes awareness campaign prevents diabetic ketoacidosis in children at their initial presentation with type 1 diabetes - King - 2012 - Pediatric Diabetes - Wiley Online Library | diabetes and more | Scoop.it

Objective
To evaluate the effect of a diabetes awareness campaign on the incidence of diabetic ketoacidosis (DKA) at the first presentation of type 1 diabetes in children (0–18 yr).............Conclusion
During the diabetes awareness campaign, the rate of DKA at initial diagnosis of type 1 diabetes in children decreased by 64%.

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CMS meeting to cut rates for non-mail diabetes supplies draws industry criticism | Drug Store News

ALEXANDRIA, Va. — The Centers for Medicare and Medicaid Services on Monday hosted a public meeting to entertain a controversial payment adjustment — called "inherent reasonableness" — in reimbursing for non-mail-order diabetes supplies.

According to published reports, CMS' authority to make payment adjustments was finalized in 2005 and can be invoked if existing reimbursements are deemed to be grossly excessive. The action comes out of the competitive bidding process for mail order, which resulted in prices more than two times lower than those for diabetic supplies sold at retail establishments.

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Genetic Screening Targets Maturity-Onset Diabetes of Youth : Family Practice News

Genetic Screening Targets Maturity-Onset Diabetes of Youth : Family Practice News | diabetes and more | Scoop.it
PHILADELPHIA – In people aged 20-40 years who have been diagnosed with diabetes, routine genetic screening for maturity-onset diabetes of youth could result in more targeted treatment.
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Docs at odds over kids' cholesterol test guidance

Docs at odds over kids' cholesterol test guidance | diabetes and more | Scoop.it
CHICAGO — Should all U.S. children get tested for high cholesterol? Doctors are still debating that question months after a government-appointed panel recommended widespread screening that would lead to prescribing medicine for some kids.

 

Fresh criticism was published online Monday in Pediatrics by researchers at one university who say the guidelines are too aggressive and were influenced by panel members' financial ties to drugmakers.

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Availability of insulin pump therapy in clinical practice - Carlsson - 2012 - Diabetic Medicine - Wiley Online Library

Availability of insulin pump therapy in clinical practice - Carlsson - 2012 - Diabetic Medicine - Wiley Online Library | diabetes and more | Scoop.it

Full text at link.

 

Conclusions At 10 hospital outpatient clinics in Sweden, use of insulin pumps therapy varied by clinic. A higher proportion of women began using insulin pumps. Younger patients and patients with fewer complications were also more likely to start using an insulin pump. Further research is needed to confirm these findings in other geographical regions and to understand whether the availability of insulin pumps today is optimized.

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Continuous Glucose Monitoring in Children and ... [Curr Diab Rep. 2012] - PubMed - NCBI

Abstract
Continuing glucose monitoring (CGM) is a relatively new and rapidly developing technology that shows promise for the future management of type 1 diabetes. When used with near-daily frequency, it has a significant effect on improvement of glucose metabolism as measured by HbA1C and reduction of hypoglycemia. It appears to be safe and actually reduces both DKA and severe hypoglycemia. Early studies indicate that it should be cost effective.

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Effect of Pramlintide on Prandial Glycemic Exc... [Diabetes Care. 2012] - PubMed - NCBI

OBJECTIVE Even under closed-loop (CL) conditions, meal-related blood glucose (BG) excursions frequently exceed target levels as a result of delays in absorption of insulin from the subcutaneous site of infusion. We hypothesized that delaying gastric emptying with preprandial injections of pramlintide would improve postprandial glycemia by allowing a better match between carbohydrate and insulin absorptions.RESEARCH DESIGN AND METHODSEight subjects (4 female; age, 15-28 years; A1C, 7.5 ± 0.7%) were studied for 48 h on a CL insulin-delivery system with a proportional integral derivative algorithm with insulin feedback: 24 h on CL control alone (CL) and 24 h on CL control plus 30-μg premeal injections of pramlintide (CLP). Target glucose was set at 120 mg/dL; timing and contents of meals were identical on both study days. No premeal manual boluses were given. Differences in reference BG excursions, defined as the incremental glucose rise from premeal to peak, were compared between conditions for each meal.RESULTSCLP was associated with overall delayed time to peak BG (2.5 ± 0.9 vs. 1.5 ± 0.5 h; P < 0.0001) and reduced magnitude of glycemic excursion (88 ± 42 vs. 113 ± 32 mg/dL; P = 0.006) compared with CL alone. Pramlintide effects on glycemic excursions were particularly evident at lunch and dinner, in association with higher premeal insulin concentrations at those mealtimes.CONCLUSIONSPramlintide delayed the time to peak postprandial BG and reduced the magnitude of prandial BG excursions. Beneficial effects of pramlintide on CL may in part be related to higher premeal insulin levels at lunch and dinner compared with breakfast.

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First Impressions of Tandem's t:slim Insulin Pump

First Impressions of Tandem's t:slim Insulin Pump | diabetes and more | Scoop.it
My first impression of the t:slim insulin pump when I saw it on the table in the hotel suite Tandem had set up shop in was “wow, it’s small.”...
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Shopping for a new insulin pump: Who's selling? | A Sweet Life

Shopping for a new insulin pump: Who's selling? | A Sweet Life | diabetes and more | Scoop.it

I have long complained about the Medtronic Continuous Glucose Monitor (CGM), but for a little while, I had made peace with the sucker because I had entered some sort of CGM zen in which I could use a single sensor for two weeks, and in a couple of cases, nearly a month. It was amazing. Two boxes lasted so long that the last few actually expired.
With longevity like that, I could overlook the inaccuracies and idiosyncrasies of the Medtronic sensor as compared to the Dexcom. It hurts like hell, but if I only need to harpoon myself once every three weeks, whatever!
But then it stopped. Two boxes of magic sensors, and now I can get maybe 7 days, if I’m lucky. Back to where I started. ....

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Caspase Inhibitor Enters Clinical Trial In Islet Transplantation As Treatment For Diabetes - The Sacramento Bee

Caspase Inhibitor Enters Clinical Trial In Islet Transplantation As Treatment For Diabetes - The Sacramento Bee | diabetes and more | Scoop.it
SAN DIEGO and EDMONTON, Alberta, July 19, 2012 -- /PRNewswire/ -- Conatus Pharmaceuticals Inc. and the University of Alberta announced today the treatment of the first patient in an investigator-initiated islet cell transplant Phase I/II trial of emricasan (IDN-6556), a pan-caspase inhibitor. The objective of the trial is to determine safety, achievement and maintenance of insulin independence and to obtain preliminary data on the efficacy of emricasan to maintain adequate immunological protection against both allo- and autoimmunity of islet cell transplant recipients. The sponsor of the trial is the University of Alberta and the principal investigator is A. M. James Shapiro, M.D., Ph.D.

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