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Important news for those concerned with all types of diabetes, associated autoimmune diseases, & health
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Jim C. Hines » Diabetes Details 11: Doesn’t That Hurt?

Jim C. Hines » Diabetes Details 11: Doesn’t That Hurt? | diabetes and more | Scoop.it

Read about Jim C. HInes, Fantasy Author with type 1 diabetes.  

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The Sheet For Type 1 Diabetes

The Sheet For Type 1 Diabetes | diabetes and more | Scoop.it

This week saw an announcement that JDRF and the Helmsley Trust will jointly fund a $4.8 million effort to develop an islet encapsulation system at the Diabetes Research Institute (DRI) of the University of Miami. This is an interesting development and something of a welcome surprise. The implications for our work on the Islet Sheet are quite positive....

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Diabetic ketoacidosis: a silent death. [Am J Forensic Med Pathol. 2012] - PubMed - NCBI

Am J Forensic Med Pathol. 2012 Sep;33(3):189-93.
Diabetic ketoacidosis: a silent death.
Ali Z, Levine B, Ripple M, Fowler DR.
Source
From the Office of the Chief Medical Examiner, State of Maryland, Baltimore, MD.
Abstract
ABSTRACT: Diabetic ketoacidosis (DKA) results from severe insulin deficiency and can be diagnosed at autopsy despite no known history of the disease. Diabetic ketoacidosis may be the initial manifestation of type 1 diabetes or may result from increased insulin requirement in type 1 diabetic patients. The purpose of this study was to determine the percentage of DKA death investigated by the Office of Chief Medical Examiner that was not associated with a known history of diabetes.Cases investigated by the Office of Chief Medical Examiner during a 6-year period whose cause of death was DKA were identified using a centralized database. To determine the percentage with known history of diabetes, investigation reports were reviewed for any documentation of this history. The toxicology reports of all DKA deaths were reviewed together with histologic slides, if available, for possible microscopic changes. Concentrations of vitreous glucose, vitreous acetone, and blood acetone were used to diagnose DKA in these autopsied cases.Nearly a third of all death from DKA (32 of 92 during a 6-year period) occurred in individuals who had no known history of diabetes, emphasizing the importance of regular physicals that include a check of glucose concentration, and especially if any warning signs are present. In a case of sudden death, it is recommended that the volatile toxicology analysis at a medical examiner's office should include tests for acetone concentration, which when elevated, together with an elevated vitreous glucose, indicates DKA.

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PLoS ONE: Engineered Vascular Beds Provide Key Signals to Pancreatic Hormone-Producing Cells

PLoS ONE: Engineered Vascular Beds Provide Key Signals to Pancreatic Hormone-Producing Cells | diabetes and more | Scoop.it

The mechanisms underlying early islet graft failure are not entirely clear, but are thought to involve ischemic injury due to delayed vascularization. We hypothesize that blood vessels play an active role in cell-cell communications supporting islet survival and engraftment. To test this hypothesis and to uncouple endothelial cell (EC)-generated signaling stimuli from their nutritional and gas exchange functions, we developed three dimensional (3D) endothelial vessel networks in engineered pancreatic tissues prepared from islets, fibroblasts and ECs. The tri-culture setup, seeded on highly porous biocompatible polymeric scaffolds closely mimics the natural anatomical context of pancreatic vasculature. Enhanced islet survival correlating with formation of functional tube-like endothelial vessels was demonstrated. Addition of foreskin fibroblasts to islet-endothelial cultures promoted tube-like structure formation, which further supported islet survival as well as insulin secretion. Gene expression profiles of EC growth factors, extracellular matrix (ECM), morphogenes and differentiation markers were significantly different in 2D versus 3D culture systems and were further modified upon addition of fibroblasts. Implantation of prevascularized islets into diabetic mice promoted survival, integration and function of the engrafted engineered tissue, supporting the suggested role of ECs in islet survival. These findings present potential strategies for preparation of transplantable islets with increased survival prospects.

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RHR: Pioneering Researcher Alessio Fasano M.D. on Gluten, Autoimmunity & Leaky Gut

RHR: Pioneering Researcher Alessio Fasano M.D. on Gluten, Autoimmunity & Leaky Gut | diabetes and more | Scoop.it
In this interview with pioneering researcher Alessio Fasano M.D., we discuss Celiac Disease, gluten, autoimmunity, and what causes leaky gut.
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Joslin Diabetes Center Diabetes Innovation 2012

Diabetes Innovation 2012 will provide a powerful foundation for sustained focus and excitement for advancement in all facets of diabetes prevention, treatment and payment reforms –from social media and gaming to translational research breakthroughs...
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You Can Do This. - YouTube

You Can Do This. - YouTube | diabetes and more | Scoop.it
You Can Do This is a growing community of videos, created by and for people with diabetes, that provides validation, hope, and encouragement through honest talk.
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Diabetes Drug Safety is Called Into Question by Avandia Maker’s Felony Plea and Actos Whistleblower’s Lawsuit : e Yugoslavia

Diabetes Drug Safety is Called Into Question by Avandia Maker’s Felony Plea and Actos Whistleblower’s Lawsuit : e Yugoslavia | diabetes and more | Scoop.it

...“The admission that GSK withheld safety data about Avandia from the FDA is similar to charges made in a whistleblower lawsuit filed by a former medical researcher for the company that makes Actos,” says attorney and consumer advocate Michael J. Evans, in a article published on ConsumerNews.com....

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Team Type 1 Going With All Diabetic Riders? | Cyclingnews.com

Team Type 1 Going With All Diabetic Riders? | Cyclingnews.com | diabetes and more | Scoop.it
Stake Laengen shown the door by American team...
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Sharps Disposal: Will Pharmacies End Up Footing the Bill? - Diabetes Health

Sharps Disposal: Will Pharmacies End Up Footing the Bill? - Diabetes Health | diabetes and more | Scoop.it
Diabetes Health - Medications: Insulin. As CEO of a company that manufactures insulin syringes and pen needles for the US and Canadian markets, I have been closely monitoring the regulations and trends pertaining to the safe disposal of the...
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Public Radio’s Kurt Andersen Tackles Misunderstandings About Diabetes

Public Radio’s Kurt Andersen Tackles Misunderstandings About Diabetes | diabetes and more | Scoop.it
Kurt Andersen developed type 1 diabetes as an adult, and his new novel features a character dealing with the disease.
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One Excellent Reason for Not Keeping Your #Diabetes a Secret

One Excellent Reason for Not Keeping Your #Diabetes a Secret | diabetes and more | Scoop.it
I can think of at least several good reasons for not keeping your diabetes a secret. It is usually a good idea to let at least a few of your close friends and/or colleagues that you see on a regular basis know you have diabetes.
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One of every 100 U.S. whites has celiac disease

One of every 100 U.S. whites has celiac disease | diabetes and more | Scoop.it
NEW YORK (Reuters Health) - One percent of non-Hispanic whites in the U.S. - close to two million Americans - have celiac disease , but most are not aware they suffer the gluten-intolerance problem, according to a new study.
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Schedule Set for First Actos Bladder Cancer Bellwether Trials

On December 29 2011 the U S Judicial Panel on Multidistrict Litigation JPML consolidated all federal Actos lawsuits into one court in the Western District of Louisiana They assigned Judge...
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Washing It Away: A 3-Year-Old's Take on Diabetes | A Sweet Life

Washing It Away: A 3-Year-Old's Take on Diabetes | A Sweet Life | diabetes and more | Scoop.it
Last week while I was giving my 3-year-old son a bath, he took his cup and began to pour water onto my hands... “I’m washing the diabetes.”...
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Splash Zone water park in Springfield, Ohio: Rule Change for Medical Conditions

Splash Zone water park in Springfield, Ohio: Rule Change for Medical Conditions | diabetes and more | Scoop.it
This is very important to our family due to the fact that my 9 year old daughter is a Type 1 Diabetic and wears a waterproof Insulin Pump called the...
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Technion/BGU finding may lead to diabetes treatment

Technion/BGU finding may lead to diabetes treatment | diabetes and more | Scoop.it
New animal research offer hope that transplants of tissue from pancreas could lead to better glucose control for diabetics.
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George Cahill, 85; authority on diabetes testified in Von Bulow trials

George Cahill, 85; authority on diabetes testified in Von Bulow trials | diabetes and more | Scoop.it
Dr. George Francis Cahill Jr. was an authority on the role of insulin in metabolism and testified in the trials of Claus von Bulow. Dr.
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Calling young diabetics - Community - Luton Today

Calling young diabetics - Community - Luton Today | diabetes and more | Scoop.it
Britain’s first ever Paediatric Diabetes East of England Games are to be held on Wednesday, August 29.
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Joe Solowiejczyk - You Can Do This

Joe Solowiejczyk shares his strategy for living well with type 1 diabetes. Recorded at the Friends For Life conference in Orlando, FL.
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GBC News, , Minister worried over 'extortion' in Ghana's health sector

GBC News, , Minister worried over 'extortion' in Ghana's health sector | diabetes and more | Scoop.it

The Minister of Health, Alban Sumana Bagbin, has expressed worry about the alleged extortion of money by some unscrupulous healthcare workers from patients before rendering legitimate services.

Mr. Bagbin consequently charged healthcare personnel to refrain from the practice which according to him is an impediment to quality healthcare delivery as well as an indictment on their reputation.

The Health Minister said this during the launch of the National Diabetes Awareness Week in Sunyani. The focus of this year’s celebration is “Self motivation; the key for survival”.

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'Organic' study of live pancreatic tissue yields new opportunities for diabetes research | Science Codex

'Organic' study of live pancreatic tissue yields new opportunities for diabetes research | Science Codex | diabetes and more | Scoop.it
TORONTO, Ontario (August 17, 2012) –An 'all-natural' method for studying pancreatic islets, the small tissues responsible for insulin production and regulation in the body, has recently been developed by researchers at the University of Toronto's...
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New sustained release hydrogel could mean twice-yearly injections for diabetes sufferers

New sustained release hydrogel could mean twice-yearly injections for diabetes sufferers | diabetes and more | Scoop.it
A new hydrogel which can provide a sustained drug release of up to six months could cut diabetes dosage down from 365 injection per year to just two, according to researchers.
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JDRF-Helmsley Charitable Trust to fund islet encapsulation research at Diabetes Research Institute

JDRF-Helmsley Charitable Trust to fund islet encapsulation research at Diabetes Research Institute | diabetes and more | Scoop.it
PHYSorg Science News Wire : JDRF-Helmsley Charitable Trust to fund islet encapsulation research at Diabetes Research Institute -- a press release is provided to you “as is” with little or no review from Phys.org staff.
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Hacking Healthcare: Are insulin pumps more susceptible to attack? | MassDevice - Medical Device Industry News

Some insulin pumps contain a dangerous combination of software security weaknesses and "convenient" features that could prevent patients from knowing that their device has been compromised, a new report says.
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