Daniel Ocaña
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Cursos online: aprende de todo y a tu propio ritmo

Cursos online: aprende de todo y a tu propio ritmo | Daniel Ocaña | Scoop.it
Udemy es una tienda virtual de aprendizaje y enseñanza online con más de 65.000 cursos y 15 millones de estudiantes. Mejora tus conocimientos de programación, marketing, ciencias de la información y mucho más.
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Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease — NEJM

Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease — NEJM | Daniel Ocaña | Scoop.it
Original Article from The New England Journal of Medicine — Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease
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Skype Translator - Traducción de voz en tiempo real

Skype Translator - Traducción de voz en tiempo real | Daniel Ocaña | Scoop.it

Hable con colegas de todo el mundo sin necesidad de conocer otros idiomas. El idioma es una de las principales barreras a la hora de mantener conversaciones fructíferas con profesionales de otros países de habla no hispana. Gracias a la tecnología, esto ya no será un problema.

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The PEARL score predicts 90-day readmission or death after hospitalisation for acute exacerbation of COPD

The PEARL score predicts 90-day readmission or death after hospitalisation for acute exacerbation of COPD | Daniel Ocaña | Scoop.it
Thorax. 2017 Feb 24. pii: thoraxjnl-2016-209298. doi: 10.1136/thoraxjnl-2016-209298. [Epub ahead of print]
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Al pie del abstract tenemos otras referencias sobre predictores evolutivos de las exacerbaciones 
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Asthma-COPD syndrome linked to higher mortality, particularly in women

Asthma-COPD syndrome linked to higher mortality, particularly in women | Daniel Ocaña | Scoop.it
Incidence and long-term outcome of severe asthma–COPD overlap compared to asthma and COPD alone: a 35-year prospective study of 57,053 middle-aged adults
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IntraMed - Puntos de vista - El culto a la mediocridad

IntraMed - Puntos de vista - El culto a la mediocridad | Daniel Ocaña | Scoop.it
Acerca del miedo al crecimento ajeno (en el minúsculo mundo de la medicina)
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La continuidad asistencial en Atención Primaria reduce los ingresos hospitalarios | Médicos y Pacientes

La continuidad asistencial en Atención Primaria reduce los ingresos hospitalarios | Médicos y Pacientes | Daniel Ocaña | Scoop.it
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(*NEW) 2017 GINA Report: Global Strategy for Asthma Management and Prevention - Global Initiative for Asthma - GINA

(*NEW) 2017 GINA Report: Global Strategy for Asthma Management and Prevention - Global Initiative for Asthma - GINA | Daniel Ocaña | Scoop.it
The 2015 update of the Global Strategy for Asthma Management and Prevention incorporates new scientific information about asthma based on a review of recent scientific literature by an international panel of experts on the GINA Science Committee.
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Top-10 comorbidities of symptomatic patients with moderate COPD in the clinical setting of the CRYSTAL study

Background: In most COPD trials a selected patient population is evaluated. The CRYSTAL study collects information on patients managed in a clinical setting. As COPD patient outcomes are partly driven by comorbidities there is a need to understand their pattern in clinical practice.

Methods: CRYSTAL evaluates efficacy and safety of switch from previous therapy directly to glycopyrronium or indacaterol/glycopyrronium fixed dose combination over 12 weeks in non-exacerbating symptomatic patients (mMRC≥1) with moderate airflow limitation (FEV1 50-80% pred.). We evaluated the Top-10 comorbidities in patients included in CRYSTAL after 1 year of recruitment.

Results: 3183 patients (mean FEV1 64.6% pred.) were recruited, of which 39.3% had mMRC≥2. Most common comorbidities were hypertension, hypercholesterolemia/hyperlipidemia, cardiovascular disease, diabetes, osteoarthritis, benign prostate hyperplasia, depression, gastroesophageal reflux disease, dyslipidemia, and osteoporosis. Cardiometabolic comorbidities were more frequent in patients with a higher mMRC grade (Table).

![Figure][1]



Conclusion: In a clinical practice setting, the majority of patients with moderate airflow limitation had significant comorbidities that were more common in more symptomatic ones. Since comorbidities have impact on patient outcomes, there is a need for careful identification and management of these, especially in the more symptomatic COPD patients.

[1]: pending:yes
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Current Controversies in the Pharmacological Treatment of Chronic Obstructive Pulmonary Disease (ATS Journals)

Current Controversies in the Pharmacological Treatment of Chronic Obstructive Pulmonary Disease (ATS Journals) | Daniel Ocaña | Scoop.it
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Vacunas en el adulto: importancia de las inmunizaciones en población sana y en grupos de riesgo

Vacunas en el adulto: importancia de las inmunizaciones en población sana y en grupos de riesgo
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Guideline 153: British guideline on the management of asthma

Guideline 153: British guideline on the management of asthma | Daniel Ocaña | Scoop.it
British guideline on the management of asthma
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Profundiza en el planteamiento de sospecha de Asma propuesto por GINA
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Omalizumab Treatment Response in a Severe Allergic Asthma Population with Overlapping COPD

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Manejo del paciente mixto... ¿nos planteamos fármacos específicos de cada una de las patologías? Montelukast...
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Una prueba única de PSA para detectar el cáncer de próstata no salva vidas (JAMA) | Univadis

Una prueba única de PSA para detectar el cáncer de próstata no salva vidas (JAMA) | Univadis | Daniel Ocaña | Scoop.it
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Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease — NEJM

Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease — NEJM | Daniel Ocaña | Scoop.it
Original Article from The New England Journal of Medicine — Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease
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Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline

Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline | Daniel Ocaña | Scoop.it
This document provides clinical recommendations for treatment of chronic obstructive pulmonary disease (COPD) exacerbations.

Comprehensive evidence syntheses, including meta-analyses, were performed to summarise all available evidence relevant to the Task Force's questions. The evidence was appraised using the Grading of Recommendations, Assessment, Development and Evaluation approach and the results were summarised in evidence profiles. The evidence syntheses were discussed and recommendations formulated by a multidisciplinary Task Force of COPD experts.

After considering the balance of desirable and undesirable consequences, quality of evidence, feasibility, and acceptability of various interventions, the Task Force made: 1) a strong recommendation for noninvasive mechanical ventilation of patients with acute or acute-on-chronic respiratory failure; 2) conditional recommendations for oral corticosteroids in outpatients, oral rather than intravenous corticosteroids in hospitalised patients, antibiotic therapy, home-based management, and the initiation of pulmonary rehabilitation within 3 weeks after hospital discharge; and 3) a conditional recommendation against the initiation of pulmonary rehabilitation during hospitalisation.

The Task Force provided recommendations related to corticosteroid therapy, antibiotic therapy, noninvasive mechanical ventilation, home-based management, and early pulmonary rehabilitation in patients having a COPD exacerbation. These recommendations should be reconsidered as new evidence becomes available.

New guideline on the management of #COPD exacerbations from @ERStalk and @atscommunity <http://ow.ly/Pvtr307YCMu>;
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foster's comment, July 21, 2017 9:55 AM



I started smoking at 15. When I was in my early 40s, i was diagnosed with chronic obstructive pulmonary disease (COPD),It was becoming increasingly worse. My dad and his dad died from this. It's a hard disease that seems to start out like bad asthma and progresses into chronic lung infections.
One day i saw a blog online,were so many people are writing about how perfect health herbal medicine cured them of COPD,so i contact perfect health herbal medicine home immediately via email,which they replied immediately too ,and told me to purchased the herbal medicine for COPD,They gave me guarantee that i will be cured with 6 weeks of usage,i believed them and purchased,after purchasing ,the herbal medicine was shipped to my home address,i received within 3 days. i used the herbal medicine for 6 weeks ,and i was totally cured of COPD ,All thanks to perfect health medicine home.please get your COPD cure immediately you see these testimony .
CONTACT DETAILS;
(Email;perfecthealthherbalmedicine gmail com)
(website:www perfecthealthherbal weebly com)

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Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts: American Journal of Respiratory and Critical Care Medicine: Vol 195, No 4

Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts: American Journal of Respiratory and Critical Care Medicine: Vol 195, No 4 | Daniel Ocaña | Scoop.it
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GOLD en 2017: una visión desde la Guía Española de la EPOC (GesEPOC)

GOLD en 2017: una visión desde la Guía Española de la EPOC (GesEPOC) | Daniel Ocaña | Scoop.it
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foster's comment, July 21, 2017 9:55 AM



I started smoking at 15. When I was in my early 40s, i was diagnosed with chronic obstructive pulmonary disease (COPD),It was becoming increasingly worse. My dad and his dad died from this. It's a hard disease that seems to start out like bad asthma and progresses into chronic lung infections.
One day i saw a blog online,were so many people are writing about how perfect health herbal medicine cured them of COPD,so i contact perfect health herbal medicine home immediately via email,which they replied immediately too ,and told me to purchased the herbal medicine for COPD,They gave me guarantee that i will be cured with 6 weeks of usage,i believed them and purchased,after purchasing ,the herbal medicine was shipped to my home address,i received within 3 days. i used the herbal medicine for 6 weeks ,and i was totally cured of COPD ,All thanks to perfect health medicine home.please get your COPD cure immediately you see these testimony .
CONTACT DETAILS;
(Email;perfecthealthherbalmedicine gmail com)
(website:www perfecthealthherbal weebly com)

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A new two-step algorithm for the treatment of COPD - Marc Miravitlles, Antonio Anzueto

A new two-step algorithm for the treatment of COPD - Marc Miravitlles, Antonio Anzueto | Daniel Ocaña | Scoop.it
The pharmacological treatment of chronic obstructive pulmonary disease (COPD) is quite uniformly based on long-acting bronchodilators (LABD), either a long-acting muscarinic antagonist (LAMA) or a long-acting β-agonist (LABA), and inhaled corticosteroids (ICS). Moreover, most patients are eventually treated with a combination of all three (LAMA/LABA/ICS or “triple therapy”) irrespective of their severity and level of risk. Furthermore, a large proportion of patients receive triple therapy as the initial treatment [1]. We propose a new simple treatment algorithm based on the severity of symptoms and phenotypes or treatable traits (figure 1).

Treatment of COPD can be simplified with a two-step algorithm according to severity and phenotype <http://ow.ly/iJUN306DEHU>;
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LAMA plus LABA versus LABA plus inhaled corticosteroid (ICS) for stable COPD - Cochrane Syst Rev

LAMA plus LABA versus LABA plus inhaled corticosteroid (ICS) for stable COPD - Cochrane Syst Rev | Daniel Ocaña | Scoop.it
Cochrane Database Syst Rev. 2017 Feb 10;2:CD012066. doi: 10.1002/14651858.CD012066.pub2. [Epub ahead of print] Review
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Buenas noticias para la pioglitazona y el cáncer de vejiga urinaria

Buenas noticias para la  pioglitazona y el cáncer de vejiga urinaria | Daniel Ocaña | Scoop.it
Buenas noticias para la  pioglitazona y el cáncer de vejiga urinaria Con esto del riesgo de padecer cáncer debido a los fármaco
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Are We Too Clean or Too Dirty? The Hygiene Hypothesis in Asthma | Clinical Correlations

Are We Too Clean or Too Dirty? The Hygiene Hypothesis in Asthma | Clinical Correlations | Daniel Ocaña | Scoop.it
By James Barger Peer Reviewed Asthma, an obstructive pulmonary disease characterized by bronchospasm and chronic airway inflammation, has afflicte
Daniel Ocaña Rodriguez's insight:
No está mal la revisión realizada por este estudiante de 3º de medicina!
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Current asthma contributes as much as smoking to chronic bronchitis in | COPD

Current asthma contributes as much as smoking to chronic bronchitis in | COPD | Daniel Ocaña | Scoop.it

Current asthma contributes as much as smoking to chronic bronchitis in middle age: a prospective population-based study

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European Medicines Agency - - Use of metformin to treat diabetes now expanded to patients with moderately reduced kidney function

European Union agency responsible for the protection of public and animal health through the scientific evaluation and supervision of medicines.
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Otro empujoncito para romper barreras
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