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Breast Cancer: Signs and Symptoms

Breast Cancer: Signs and Symptoms | Cancer News research and study | Scoop.it
Breast cancer is the most common cancer afflicting many women around the world.
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Selenium, Vitamin E supplements raise prostate cancer risk | Health Newsline

Selenium, Vitamin E supplements raise prostate cancer risk | Health Newsline | Cancer News research and study | Scoop.it
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India-made medicines come under FDA scanner over safety, quality concerns | Health Newsline

India-made medicines come under FDA scanner over safety, quality concerns | Health Newsline | Cancer News research and study | Scoop.it
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Glance into the Past: Brain Cancer: A new technique emerges to help people | Scivista

Glance into the Past: Brain Cancer: A new technique emerges to help people | Scivista | Cancer News research and study | Scoop.it
A new scanning technique developed by Danish and US researchers reveals how susceptible patients with aggressive brain cancer are to the drugs they receive.
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Novel agent set for unique clinical test in inflammatory breast cancer

Novel agent set for unique clinical test in inflammatory breast cancer | Cancer News research and study | Scoop.it

"A drug now used to treat a type of lymphoma has shown surprising benefit in preclinical studies of inflammatory breast cancer, according to a researcher at Thomas Jefferson University's Kimmel Cancer Center.

The finding, published online this month in the Journal of Experimental Therapeutics and Oncology, has led to development of a phase 1/2 clinical trial at Kimmel Cancer Center to test the agent, Romidepsin (Istodax), in combination with nab-paclitaxel (Abraxane) chemotherapy for advanced inflammatory breast cancer (IBC).

"Because this kind of breast cancer is very difficult to treat, we hope this new combination of anticancer agents will change the outcome of this aggressive disease," says the study's senior investigator, Massimo Cristofanilli, M.D., F.A.C.P., Professor of Medical Oncology and Director of the Jefferson Breast Care Center.

The study was conducted in collaboration with the lead author, Fredika Robertson, Ph.D., at The University of Texas M. D. Anderson Cancer Center, and was supported by a Promise Grant from the Susan G Komen Foundation awarded to Drs. Cristofanilli and Robertson in 2008."


Via Curated by A4BC.ORG, Heather Swift
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The importance of sex in the midst of a cancer diagnosis

The importance of sex in the midst of a cancer diagnosis | Cancer News research and study | Scoop.it
It occurs to me that I talk to my patients more about death and dying, than about sex.

Via Tambre Leighn
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Tambre Leighn's curator insight, December 26, 2013 3:44 PM

Beautifully written article about the importance of intimacy in survivorship.

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WHO: Cancer Risk Rising Around the World; Western Medicine Failing Globally

WHO: Cancer Risk Rising Around the World; Western Medicine Failing Globally | Cancer News research and study | Scoop.it
WHO: Cancer risk rising around the world; Western medicine failing globally

Via Graham Player Ph.D.
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Graham Player Ph.D.'s curator insight, December 27, 2013 11:21 PM

By 2025, WHO claims, the annual number of new cancer diagnoses is expected to increase by roughly 37%.

The number of cancer patients that will end up dying from the disease or its corresponding treatment is also expected to rise by about 39%.

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Indian students develop mobile app that detects skin cancer

Indian students develop mobile app that detects skin cancer | Cancer News research and study | Scoop.it
Mobile technology has dramatically transformed the way we live and work.
themedguru's insight:

This is really amazing.

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Breast Cancer: Breast Reconstruction Surgery

Breast Cancer: Breast Reconstruction Surgery | Cancer News research and study | Scoop.it
WebMD links you to articles about choosing breast reconstruction surgery after mastectomy.

Via Heather Swift
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Breast Cancer: Tamoxifen Metabolite Promising

Breast Cancer: Tamoxifen Metabolite Promising | Cancer News research and study | Scoop.it
SAN ANTONIO -- In the first human experience with a drug that is the main metabolite of tamoxifen, promising responses were observed in woman diagnosed with aromatase inhibitor resistant, metastatic b...

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Heather Swift's curator insight, December 17, 2013 11:38 PM

Breast Cancer: Tamoxifen Metabolite Promising SAN ANTONIO -- In the first human experience with a drug that is the main metabolite of tamoxifen, promising responses were observed in woman diagnosed with aromatase inhibitor resistant, metastatic breast cancer, researchers said here.

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A breathalyzer to detect lung cancer?

A breathalyzer to detect lung cancer? | Cancer News research and study | Scoop.it

Early detection of lung cancer can improve prognosis of the disease. Thus, British researchers are working on developing a test that can pick up early traits of the disease, making cure more likely.

A team of experts at the University of Huddersfield are developing a breathalyzer test that can detect very early signs of the malignancy.

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The Next Front in Cancer Care

The Next Front in Cancer Care | Cancer News research and study | Scoop.it
As more patients survive, cancer-care centers increasingly help them address the daunting physical and emotional challenges of being a survivor.

Via Marie Ennis-O'Connor
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Breast-Feeding may Reduce Risk of Breast Cancer | kodjoworkout.com

Breast-Feeding may Reduce Risk of Breast Cancer | kodjoworkout.com | Cancer News research and study | Scoop.it
Women who suffer from hereditary breast cancer due to the mutation of the BRCA1 and BRCA2 too can gain from breastfeeding.

Via Pratima Patil
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Cooking meat with dark beer may reduce cancer risk

Cooking meat with dark beer may reduce cancer risk | Cancer News research and study | Scoop.it
According to a recent study, soaking meat in dark beer can reduce the amount of polycyclic aromatic hydrocarbons (PAHs), the carcinogens produced by the meat when cooked at very high temperatures. In several lab tests, the PAHs, which also exist in cigarette smoke and car exhaust, have been linked to cancers, birth defects, and reproductive problems in animals. The study, carried out by a group of European scientists at the University of Vigo in Spain and University of Porto in Portugal, suggests that beer marinades are an excellent way of reducing PAHs in grilled meat.
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Regular Vitamin C intake may ward off hemorrhagic stroke risk | Health Newsline

Regular Vitamin C intake may ward off hemorrhagic stroke risk | Health Newsline | Cancer News research and study | Scoop.it
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Robots to use Steerable needles to treat blood clot | Scivista

Robots to use Steerable needles to treat blood clot | Scivista | Cancer News research and study | Scoop.it
Scientists believe that the clots that form inside the brain are the leading cause of disability and death. The odds of a person getting an intra-cerebral hemorrhage are one in 50 over his or her lifetime.
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Inhibition of Protein Kinase C / Twist1 Signaling Augments Anti-Cancer Effects of Androgen Deprivation and Enzalutamide in Prostate Cancer

"Our findings indicate that PKC/Twist1 signaling contributes to castration resistance as well as enzalutamide resistance in prostate cancer, and suggest that therapeutics targeting PKC/Twist1 signaling, such as PKC inhibitors, represent a promising novel therapeutic strategy for prostate cancer, especially castration-resistant prostate cancer, when combined with enzalutamide."


Via Cancer Commons
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Cancer Commons's curator insight, December 19, 2013 1:01 PM

Shiota M, Yokomizo A, Takeuchi A,  Imada K et al.

Clinical Cancer Res., Dec 18 2013

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Why Treatment for Bladder Cancer Is Dangerous for Us? by Apac Biotech

Why Treatment for Bladder Cancer Is Dangerous for Us? by Apac Biotech | Cancer News research and study | Scoop.it

Bladder cancer is the most common cancer in India; it comes on 5th rank in cancer. Almost 50,000 peoples diagnosed every year, and more than 15,000 peoples will die from these diseases. This cancer is...


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Apac Biotech's curator insight, December 24, 2013 7:39 PM

Bladder cancer is the most common cancer in India; it comes on 5th rank in cancer. 

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Kidney Cancer

Kidney Cancer | Cancer News research and study | Scoop.it
The kidneys are a pair of organs on either side of the spine in the lower abdomen. Each kidney is about the size of a fist. Attached to the top of each kidney is an adrenal gland. A mass of fatty t...

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Biomarker data improve breast cancer staging accuracy

Biomarker data improve breast cancer staging accuracy | Cancer News research and study | Scoop.it

"NEW YORK (Reuters Health) - Inclusion of estrogen receptor, progesterone receptor, and human epidermal growth factor 2 (HER2) status could improve the prognostic accuracy of breast cancer staging, according to a new study.

"I believe it is time that we consider biomarkers in our staging system which has been purely anatomic in the past," Dr. Armando E. Giuliano from Cedars-Sinai Medical Center in West Hollywood, California, told Reuters Health by email. "This would improve communication and prognostication."

The current TNM staging system, based as it is strictly on anatomic factors, ignores the prognostic impact of tumor biology, Dr. Giuliano and colleagues noted in JAMA Surgery, online December 4.

The researchers investigated whether the addition of the triple-negative phenotype (TNP; negative expression of estrogen receptor, progesterone receptor, and HER2) to the TNM staging would influence the accuracy of TNM prognosis.

Their study included 1,842 women with breast cancer, 280 (15.2%) of whom were diagnosed with TNP breast cancer. During a median 4.3 years of follow-up, the survival curves for patients with TNP were similar to those for patients with non-TNP at the next higher stage.

In other words, five-year overall survival for stage I TNP (92.3%) was similar to stage II non-TNP (93.4%); for stage II TNP (83.9%) was similar to stage III non-TNP (78.5%); and for stage III TNP (58.4%) approached stage IV non-TNP (34.6%, p=0.76). Five-year overall survival for stage IV TNP was only 14.3%."


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Curated by A4BC.ORG's curator insight, December 27, 2013 4:28 PM

According to the article, stage reclassification that incorporates triple negative phenotype TNP status can be a first step in recognizing the importance of nonanatomic factors and could help clinicians provide better cancer care. 

To see the abstract go to: http://archsurg.jamanetwork.com/article.aspx?articleid=1788160


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Can a tomato-rich diet slash the risk of breast cancer?

Can a tomato-rich diet slash the risk of breast cancer? | Cancer News research and study | Scoop.it

Over the years tomatoes have been touted as a healthful food that is good for us! Now a new study claims, the lush, red, juicy fruit can help slash the risk of breast cancer in postmenopausal women.

Researchers theorize that the secret may lie in the antioxidant lycopene that makes tomatoes red. Lycopene helps neutralize the damaging free radicals in the body that are implicated in various kinds of malignancies.

The study found lycopene helps in regulating the hormones that control fat levels and sugar metabolism in body. As per the National Cancer Institute, obesity is considered the main culprit behind
breast cancer.

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What the Hell Is A Cancer Coach? | I Had Cancer.

What the Hell Is A Cancer Coach? | I Had Cancer. | Cancer News research and study | Scoop.it
Ever wish that you had someone to guide you along the way through your cancer fight? We have basketball coaches and football coaches, but who knew that there were actual coaches for cancer? So what the hell do they do?

Via Tambre Leighn
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The 24 Best Breast Cancer Health Blogs of 2013

The 24 Best Breast Cancer Health Blogs of 2013 | Cancer News research and study | Scoop.it
Many passionate bloggers focus on the topic of breast cancer, and you can learn from them. Read on for the 24 Best Breast Cancer Health Blogs of 2013.

Via Pratima Patil
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Patients with metastatic breast cancer may not benefit from surgery and radiation after chemotherapy

Patients with metastatic breast cancer may not benefit from surgery and radiation after chemotherapy | Cancer News research and study | Scoop.it

"SAN ANTONIO — After a response to initial chemotherapy, treatment with radiotherapy and surgical removal of the breast tumor and nearby lymph nodes do not provide any additional benefit to patients with metastatic breast cancer, according to results of a clinical trial presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

"There is a small percentage, about 5 to 20 percent of breast cancer patients, who present with metastatic breast cancer when they see their doctors for the first time, and across the globe, the thought is that the local tumor in such events does not require any surgery or radiation [known as loco-regional treatment (LRT)] after chemotherapy, unless there is bleeding or ulceration," said Rajendra Badwe, M.D., director of the Tata Memorial Hospital in Mumbai, India. "However, there are conflicting results from retrospective analyses, and hence, there was a need for a randomized trial.

"We found that there was no difference in overall survival between those who received LRT and those who did not receive LRT," explained Badwe. "Indeed, there was a 7 percent excess death rate in those who received LRT. This finding was not statistically significant; nevertheless, it aligns with previous preclinical findings that suggest surgical removal of the primary tumor bestows a growth advantage on metastases.

"I'm sure a lot of oncologists who believe in conventional wisdom and don't provide loco-regional treatment will feel a lot more comfortable looking at these results," said Badwe. "As for those who have changed practice based on the retrospective study history, they would have to rethink."

Badwe and colleagues conducted a prospective, randomized, controlled trial, to which they recruited 350 women between 2005 and 2013. Eligible patients had metastatic breast cancer and an objective tumor response to six cycles of chemotherapy. Patients were randomized to two arms: 173 women received LRT (LRT arm) and 177 women received no LRT (no-LRT arm). Both arms were matched for age, clinical tumor size, hormone receptor and HER2 receptor status, and status of disease spread.

Patients in the LRT arm underwent partial or complete surgical removal of their breasts and surgical removal of axillary lymph nodes, followed by radiotherapy. Patients in the no-LRT arm did not receive any surgery or radiotherapy. Patients from both arms whose breast cancers were hormone-related received standard hormone therapy. The primary endpoint of the study was overall survival. Nine patients from the LRT arm and three patients from no-LRT arm could not adhere to trial protocol."


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Improve winter mood and enegry | MD Anderson Cancer Center

Improve winter mood and enegry | MD Anderson Cancer Center | Cancer News research and study | Scoop.it
Winter may make you feel sad and sluggish. Get ways to improve your mood and energy.

Via Tambre Leighn
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Tambre Leighn's curator insight, December 9, 2013 9:44 AM

And, I'm adding a 7th tip...my personal favorite way to keep up my energy, my spirits and my soclal connection...dance.  There is no such thing as two left feet - the truly masterful instructors can teach anyone the basics of a dance. 

 

The great thing about dance is there are so many kinds to choose from...country two step not your thing (definitely not mine), you can waltz, salsa, hustle, tango and more.  Most dance communities are filled with like minded people, open to trying new things and not interested in being a couch potato.  Most dances can be done at a basic level with great enjoyment.  I personally love Argentine Tango and while you can do a lot of fancy moves with it, the beauty of the dance is in the basic walk.  Even the greatest spend hours practicing the walk and when done properly can be as mesmerizing as any lift, spin or dip you'll see out there on the dance floor.

 

For singles, its a great way to meet people and for couples, there's nothing like learning to connect and communicate without words.  This holiday season, I invite you to avoid the blues by giving dance a try...just experiment with a lesson or two in a group format and see if you don't find yourself smiling and feeling more energized.