Cancer
5 views | +0 today
Follow
Your new post is loading...
Your new post is loading...
Scooped by RafeefBaamer
Scoop.it!

Animated Introduction to Cancer Biology (Full Documentary)

An animation/video teaching the basics of how cancer forms and spreads. Topics include: mutation, tumor suppressors, oncogenes, angiogenesis, apoptosis, meta...
more...
No comment yet.
Scooped by RafeefBaamer
Scoop.it!

Daily Aspirin May Help Prevent Cancer, Study Shows – WebMD

Daily Aspirin May Help Prevent Cancer, Study Shows – WebMD | Cancer | Scoop.it
6, 2014 (HealthDay News) -- Taking aspirin every day appears to reduce the odds of developing and dying from colon, stomach or esophageal cancer, a new study suggests. Based on a review of available studies, ...
more...
No comment yet.
Scooped by RafeefBaamer
Scoop.it!

Killing cancer by protecting normal cells

Although radiation treatments have become much more refined in recent years, it remains a challenge to both sufficiently dose the tumor while sparing the surrounding tissue. A new anti-cancer drug, already in clinical development, may help address this issue by protecting normal cells - but not the cancer - from the effects of radiation. The research, published November 14th in Molecular Cancer Therapeutics, further suggests this drug may also be useful in treating accidental exposure to radiation.

"It was a stroke of luck that the drug that most effectively protected normal cells and tissues against radiation also has anti-cancer properties, thus potentially increasing the therapeutic index of radiation therapy," says Ulrich Rodeck, M.D., Ph.D., Professor of Dermatology and Cutaneous Biology and Radiation Oncology at Thomas Jefferson University, and senior author on the study.

Together with first author Vitali Alexeev, Ph.D., Assistant Professor, Dermatology and Cutaneous Biology, Dr. Rodeck and colleagues tested five compounds that were shown to have radiation-protective properties in earlier studies. The researchers gave the mice one of the five compounds a day before and for several days after radiation treatment. A compound called RTA 408 emerged from this screen as a robust radiation protector and its effect was comparable to the only drug currently approved by the FDA for that purpose. (The approved drug, called amifostine, however, has a number side effects including severe nausea or vomiting that make it an unappealing choice for clinicians.) Sites that are usually most susceptible to radiation damage including the gut and blood cells in the bone marrow were both protected in mice treated with RTA 408.

Using human prostate cancer cells growing in mice, the researchers also showed that RTA 408 did not confer radiation protection to the cancer cells. In fact, when RTA 408 was given alone, without radiation, it also slowed the growth of human prostate cancer transplants in mice. In combination, it further amplified the tumor growth inhibitory effects of radiation.

"It was really exciting to see," says Dr. Rodeck, "that combining radiation and RTA-408 more effectively inhibited tumor growth compared to using either one or the other as single treatment modalities."

Dr. Rodeck and colleagues plan to continue to unravel the molecular underpinnings of these radiation-protective effects in order to understand how exactly this compound works and how its mechanism of action might be improved for clinical applications.

RTS 408 is currently being developed by REATA pharmaceuticals for a number of clinical applications, including a trial currently enrolling patients for a topical form of the drug applied to patients who experience radiation dermatitis.

more...
No comment yet.
Scooped by RafeefBaamer
Scoop.it!

3D Medical Animation - What is Cancer?

"What is Cancer?" is a 3D Animation which depicts the growth of a tumor. (music by: Bjorn Lynne - Blissful Moments, courtesy of www.Shockwave-Sound.com)
more...
No comment yet.
Rescooped by RafeefBaamer from Breast Cancer News
Scoop.it!

Researchers Find Shape-shifting Stops Migrating Cancer Cells

Researchers Find Shape-shifting Stops Migrating Cancer Cells | Cancer | Scoop.it

"JACKSONVILLE, Fla. — Like a car with a front and back end, a steering mechanism and an engine to push it forward, cancer cells propel themselves through normal tissues and organs to spread cancer throughout the body. Researchers at Mayo Clinic in Florida, however, have managed to turn these cells into shapes like a round fried egg and an exaggerated starfish that sticks out in many directions — both of which cannot now move.

In research published in the December issue of Molecular and Cellular Biology, investigators reveal how interplay of molecules keeps cancer cells moving forward, and how disturbing the balance of these proteins pushes their shape to change, stopping them in their tracks.

Investigators say they have already identified a number of agents — some already used in the clinic for different disorders — that may force shape-shifting in tumor cells.

"We are starting to understand mechanistically how cancer cells move and migrate, which gives us opportunities to manipulate these cells, alter their shape, and stop their spread," says the study's lead investigator, Panos Z. Anastasiadis, Ph.D., chair of the Department of Cancer Biology at Mayo Clinic in Florida.".    


Via Curated by A4BC.ORG
more...
Rescooped by RafeefBaamer from Longevity science
Scoop.it!

New discovery of the ways cells move could boost understanding of spread of cancer | KurzweilAI

New discovery of the ways cells move could boost understanding of spread of cancer | KurzweilAI | Cancer | Scoop.it
Epithelial cells (credit: Mulletsrokk/Wikimedia Commons) Led by researchers at Harvard School of Public Health (HSPH) and the Institute for Bioengineering

Via Ray and Terry's
more...
No comment yet.