breast, prostate, pancreatic cancer
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OncoBriefs: Delayed Tx for Prostate Ca, New Antiandrogen

OncoBriefs: Delayed Tx for Prostate Ca, New Antiandrogen | breast, prostate, pancreatic cancer | Scoop.it
CHICAGO -- Prostate cancer mortality has declined by more than 60% compared with historical data for a cohort of conservatively managed patients followed for more than 20 years, a retrospective analys
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Prostate cancer mortality has declined by more than 60% to around 6-7% compared with historical data.

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How Big Pharma Holds Back in the War on Cancer

How Big Pharma Holds Back in the War on Cancer | breast, prostate, pancreatic cancer | Scoop.it
Big Pharma’s focus on blockbuster cancer drugs squeezes out cheaper treatments. The result, one researcher says: ‘If we’re winning the war on cancer, we’re not winning that fast.’
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An associate professor of medicine at Harvard Medical School has been trying for years to raise money for trials on the effects of aspirin on breast cancer, since studies suggest aspirin might help inhibit breast cancer from spreading. Yet because this drug couldn't be patented, it won't get a randomized trial.

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ASCO: Treating BRCA-Positive Breast Cancer | Cancer Network

ASCO: Treating BRCA-Positive Breast Cancer | Cancer Network | breast, prostate, pancreatic cancer | Scoop.it

 

As part of our coverage of the 2014 ASCO Annual Meeting, we discuss treatment strategies for breast cancer patients who harbor either the BRCA1 or BRCA2 mutation.
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I was really interested to read Susan Domchek's comments about Platinum therapy for mets in BRCA1/2 patients.

 

"There are definitely many women who chose to have a bilateral mastectomy at the time of their initial diagnosis rather than, for instance, a lumpectomy and radiation therapy. And this is really a specific issue in BRCA1/2 mutation carriers, because there is a very high risk of a second primary breast cancer. The other factor to consider is an oophorectomy or a removal of the ovaries in this situation."

 - Susan Domchek

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OncoBriefs: Prostate, Pancreatic, and Renal Cancer

OncoBriefs: Prostate, Pancreatic, and Renal Cancer | breast, prostate, pancreatic cancer | Scoop.it
A link between low testosterone and prostate cancer progression and an Achilles' heel for pancreatic cancer are among oncology-related developments that have made news recently.
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Research reports say inhibition of a single protein stopped the growth of pancreatic cancer in mice and human pancreatic cancer cells, according to a report in Science Signaling.

 

Deletion of Yes-associated protein (YAP) stopped tumor growth without adversely affecting adjacent normal tissue.

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ASCO: OK to Cut Back on Bone Mets Therapy

ASCO: OK to Cut Back on Bone Mets Therapy | breast, prostate, pancreatic cancer | Scoop.it
CHICAGO -- Less frequent dosing of zoledronic acid (Zometa) after the first year in breast cancer metastatic to the bone was just as good for preventing skeletal events with potentially less toxicity,
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This study concludes that the drug builds up in year 1 and can be maintained with less frequent dosing thereafter.

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Adjuvant Exemestane with Ovarian Suppression in Premenopausal ...

Adjuvant Exemestane with Ovarian Suppression in Premenopausal ... | breast, prostate, pancreatic cancer | Scoop.it
In two phase 3 trials, we randomly assigned premenopausal women with hormone-receptor–positive early breast cancer to the aromatase inhibitor exemestane plus ovarian suppression or tamoxifen plus ovarian suppression ...
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Exemestane appears to be having better outcomes than other ovarian suppression drugs...

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