Biomarkers and Personalized Medicine
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Biomarkers and Personalized Medicine
Sharing relevant articles on advancements in personalized medicine
Curated by Brian Shields
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GeneAssess Financed to Validate Predictive Cancer Biomarker

GeneAssess Financed to Validate Predictive Cancer Biomarker | Biomarkers and Personalized Medicine | Scoop.it

GeneAssess raises $500K in funding to assess FRY as a biomarker for Breast Cancer

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UT MD Anderson Research Finds Predictive Value of Circulating Tumor Cells in Early Stage Breast Cancer

UT MD Anderson Research Finds Predictive Value of Circulating Tumor Cells in Early Stage Breast Cancer | Biomarkers and Personalized Medicine | Scoop.it

"Circulating tumor cells (CTCs), established in the metastatic breast cancer setting for predicting a woman’s chance of recurrence and survival, have now shown similar value in early stage breast cancer..."

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DailyTech - Researchers Discover Possible Breast Cancer Biomarker in "Junk" DNA

DailyTech - Researchers Discover Possible Breast Cancer Biomarker in "Junk" DNA | Biomarkers and Personalized Medicine | Scoop.it
Newly discovered biomarkers could indicate risk of developing breast cancer...
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Whole-genome sequencing may help fight triple-negative cancer | R&D Mag

Whole-genome sequencing may help fight triple-negative cancer | R&D Mag | Biomarkers and Personalized Medicine | Scoop.it
Initial results from an ongoing clinical trial, the first designed to examine the utility of whole-genome sequencing for breast cancer, indicate activation of targets not previously associated with so-called triple negative disease, which...
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Breast Cancer Genetic Profiling Has Not Achieved Personalized Medicine Yet - Medical News Today

Breast Cancer Genetic Profiling Has Not Achieved Personalized Medicine Yet - Medical News Today | Biomarkers and Personalized Medicine | Scoop.it

"Although ten years of genetic profiling has had an enormous impact on the understanding of breast cancer, progress on individualizing therapy has been rather limited, researchers from the UK and USA reported in The Lancet this week..."

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Johns Hopkins Researcher Wins Prize For Breast Cancer Biomarker Studies

Johns Hopkins Researcher Wins Prize For Breast Cancer Biomarker Studies | Biomarkers and Personalized Medicine | Scoop.it
A Johns Hopkins breast cancer researcher is the recipient of a $50,000 award designed to encourage rapid translation of her basic research on biomarkers into a commercially available test that could predict the best treatment options for some women...
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BOLERO2 data in breast cancer impresses at ECCO 2011

BOLERO2 data in breast cancer impresses at ECCO 2011 | Biomarkers and Personalized Medicine | Scoop.it
This year I decided to write some longer posts from the ECCO/EMCC meeting owing to the amount of potentially paradigm changing data coming out. These in depth op eds will roll out over the next few days.
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IU investigators find biomarker that predicts taxane-induced neuropathy among breast cancer patients | cancer

IU investigators find biomarker that predicts taxane-induced neuropathy among breast cancer patients | cancer | Biomarkers and Personalized Medicine | Scoop.it
IU investigators find biomarker that predicts taxane-induced neuropathy among breast cancer patients...
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The CYP2C19*2 genotype predicts tamoxifen treatment outcome in advanced breast cancer patients

The CYP2C19*2 genotype predicts tamoxifen treatment outcome in advanced breast cancer patients http://bit.ly/reQXFV...
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PTEN is an important tumor suppressor gene in breast cancer

PTEN is an important tumor suppressor gene in breast cancer | Biomarkers and Personalized Medicine | Scoop.it
An interesting new paper has just appeared in the latest online first edition of Cancer Discovery, and discusses a functional classification for evaluating the alterations in breast cancer to ultimately determine which are drivers...
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Irina Bcra's curator insight, December 30, 2016 7:25 AM

We are an independent charity that supports innovative breast cancer research across the UK.

We aim to help beat breast cancer and save lives by supporting ground-breaking research.

Through our fundraising we support research organisations to develop and run breast cancer research programmes. These programmes enable huge steps to be taken in improving the prevention and treatment of breast cancer – the most common type of cancer in the UK.

http://breastcancerresearchaid.org.uk/

Irina Bcra's curator insight, January 17, 2017 1:06 AM
We are an independent charity that supports innovative breast cancer research across the UK. We aim to help beat breast cancer and save lives by supporting ground-breaking research. Through our fundraising we support research organisations to develop and run breast cancer research programmes. These programmes enable huge steps to be taken in improving the prevention and treatment of breast cancer – the most common type of cancer in the UK. http://breastcancerresearchaid.org.uk/
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Targeted therapies: Bevacizumab[mdash]has it reached its final resting place? : Article : Nature Reviews Clinical Oncology

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Biocept, Inc. Announces Availability of Its New Breast Cancer Test, OncoCEE-BR™ Utilizing Circulating Tumor Cells (CTCs)

Biocept, Inc. Announces Availability of Its New Breast Cancer Test, OncoCEE-BR™ Utilizing Circulating Tumor Cells (CTCs) | Biomarkers and Personalized Medicine | Scoop.it
SAN DIEGO, July 28, 2011 /PRNewswire/ -- Biocept, Inc., an advanced diagnostic CLIA-certified service laboratory...
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A Simple Way to Detect Breast Cancer at 'Stage 0' Discovered | FreshNews.com

GERMANTOWN, Md., July 22, 2011 /PRNewswire/ -- RNL Natural Co., Ltd, a leading biotech company specialized in adult stem cell therapeutics affiliated with RNL BIO Co., Ltd., introduced on June 22, 2011 a new method of detecting breast cancer as early...
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Vanderbilt-led Study Identifies Genes Linked to Resistance to Breast Cancer Chemotherapy

Vanderbilt-led Study Identifies Genes Linked to Resistance to Breast Cancer Chemotherapy | Biomarkers and Personalized Medicine | Scoop.it
A study led by Vanderbilt-Ingram Cancer Center (VICC) investigators has identified a gene expression pattern that may explain why chemotherapy prior to surgery isn’t effective against some tumors...Read the whole entry... »...
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RNAi as a potential biomarker for early breast cancer | Pharma Strategy Blog

RNAi as a potential biomarker for early breast cancer | Pharma Strategy Blog | Biomarkers and Personalized Medicine | Scoop.it
Microarray-based miRNA profiling from peripheral blood could be combined with other markers to improve screening and early detection of cancer. (RT @drsteventucker: Great post!
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What’s hot at SABCS – Update 2 – advanced breast cancer

What’s hot at SABCS – Update 2 – advanced breast cancer | Biomarkers and Personalized Medicine | Scoop.it
After a number of basic research and science sessions over the last two days (see the Update 1 post on the science that intrigued me for more details), but the last two days heralded some excellent clinical sessions, in both oral and poster forms.
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Video preview of San Antonio Breast Cancer Symposium 2011

What’s hot at the 2011 San Antonio Breast Cancer Symposium?
There is a lot of exciting data coming out at SABCS 2011 over the next three days, including the BOLERO2, CLEOPATRA and NEOSPHERE clinical trial data.
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Redefining subsets of triple negative breast cancer

Redefining subsets of triple negative breast cancer | Biomarkers and Personalized Medicine | Scoop.it
Heterogeneity remains one of the biggest barriers to progress in clinical research. Triple negative breast cancer is an excellent example of this conundrum as I’ve said many times here on this blog – it’s defined not what it is but what it’s not.
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New breast cancer test created and available in Tucson

New breast cancer test created and available in Tucson | Biomarkers and Personalized Medicine | Scoop.it
The test can shorten the length of time a patient must wait between diagnosis and treatment for a certain type of breast cancer.
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Inhibition of EGFR phosphorylation in a panel of human breast cancer cells correlates with synergistic interactions between gefitinib and 5′-DFUR, the bioactive metabolite of Xeloda®

Inhibition of EGFR phosphorylation in a panel of human breast cancer cells correlates with synergistic interactions between gefitinib and 5′-DFUR, the bioactive metabolite of Xeloda® | Biomarkers and Personalized Medicine | Scoop.it

"The results, in toto, suggest that the extent of modulation of TP by gefitinib may be used as a predictor of tumour sensitivity to gefitinib + capecitabine/5′-DFUR combinations."

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The p53 breast cancer tissue biomarker in Indian women

The p53 breast cancer tissue biomarker in Indian women | Biomarkers and Personalized Medicine | Scoop.it
Peer reviewed article authored by (Patil V, Tayade M, Pingale S, Dalvi S, Rajekar R, Deshmukh H, Patil S, Singhai R). Read article or submit your manuscript for publishing.
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Roche Seeks ‘Middle Ground’ in U.S. Appeal of Avastin Breast Cancer Ruling

Roche Holding AG asked U.S. regulators to keep Avastin on the market for breast cancer in what the drugmaker called a “middle-ground proposal” while it conducts another clinical trial.
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Control of VEGF Expression in Triple-Negative Breast Carcinoma Cells by Suppression of SAF-1 Transcription Factor Activity

Control of VEGF Expression in Triple-Negative Breast Carcinoma Cells by Suppression of SAF-1 Transcription Factor Activity | Biomarkers and Personalized Medicine | Scoop.it
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Targeted therapies: Peaking beneath the surface of recent bevacizumab trials : Article : Nature Reviews Clinical Oncology

Targeted therapies: Peaking beneath the surface of recent bevacizumab trials : Article : Nature Reviews Clinical Oncology | Biomarkers and Personalized Medicine | Scoop.it
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Cancer Cell - Targeting Androgen Receptor in Estrogen Receptor-Negative Breast Cancer

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