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Rescooped by Janna Kaixer from Stem Cells & Tissue Engineering
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Developmental on-switch: Substances that convert body cells back into stem cells initially activate all genes in the embryo

Developmental on-switch: Substances that convert body cells back into stem cells initially activate all genes in the embryo | Biology | Scoop.it
Researchers have demonstrated for the first time why the molecular cocktail responsible for generating stem cells works.

Via Jacob Blumenthal
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Jacob Blumenthal's curator insight, August 19, 2013 6:44 AM

Researchers from Freiburg university found that zebrafish Pou5f1, a homolog of the mammalian pluripotency transcription factor Oct4, occupies SOX-POU binding sites before the onset of zygotic transcription and activates the earliest zygotic genes. 

The paper was published in Science:

http://www.sciencemag.org/content/early/2013/08/14/science.1242527

 

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To learn about stem cells and their related differentiation protocols:

http://discovery.lifemapsc.com/stem-cell-differentiation/in-vitro-cells

http://discovery.lifemapsc.com/stem-cell-differentiation/protocols

 

Scooped by Janna Kaixer
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Researchers map genetics of 30 common cancers - Nursing Times

Researchers map genetics of 30 common cancers - Nursing Times | Biology | Scoop.it
Researchers map genetics of 30 common cancers Nursing Times “Cancer 'signatures' reveal origins of disease,” Sky News reports, explaining how “a team of scientists discover the genetic patterns left by complex processes which mutate DNA and lead to...
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