Biocódices Blog
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Biocódices Blog
We are a technology-based company dedicated to the research and development of innovative genomic products and services for application in health, agriculture, livestock and the environment.
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Modifican genes en embriones humanos para evitar enfermedades 

Modifican genes en embriones humanos para evitar enfermedades  | Biocódices Blog | Scoop.it
Hazaña: modifican genes en embriones humanos para evitar enfermedades | Por primera vez, logran eliminar una mutación que causa cardiomiopatía hipertrófica, un desorden que puede producir muerte súbita; controversia por su aplicación práctica - LA NACION
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CRISPR Eliminates HIV in Live Animals 

CRISPR Eliminates HIV in Live Animals  | Biocódices Blog | Scoop.it
New research reveals that HIV DNA can be excised from the genomes of living animals to eliminate further infection
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Genome-based diets maximise growth, fecundity, and lifespan

Genome-based diets maximise growth, fecundity, and lifespan | Biocódices Blog | Scoop.it
A new developed diet for fruit flies increases growth and fecundity without shortening life-span
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Scientists Hack a Human Cell and Reprogram It Like a Computer

Scientists Hack a Human Cell and Reprogram It Like a Computer | Biocódices Blog | Scoop.it
By hijacking the DNA of a human cell, they showed it's possible to program it like a simple computer.
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Scientists just changed the way we build genomes to make them 270,000 times cheaper

Scientists just changed the way we build genomes to make them 270,000 times cheaper | Biocódices Blog | Scoop.it
In 2003, the US Department of Defense and the National Institutes of Health announced that—13 years and $2.7 billion later—they had finally finished mapping the human genome. But the quest to understand human genetics was far from over: Genomes, which are the entire layout of our 3 billion base pairs of DNA, vary dramaticall
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Researchers create world's first 'menstrual cycle on a chip'

Researchers create world's first 'menstrual cycle on a chip' | Biocódices Blog | Scoop.it
A new device, created at Northwestern University in Chicago, Illinois, hailed as the world's first 'menstrual cycle on a chip' has been created to develop individualized treatments for women.
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Genetic details of controversial 'three-parent baby' revealed

Genetic details of controversial 'three-parent baby' revealed | Biocódices Blog | Scoop.it
But the child's parents have decided to forego long-term monitoring by researchers.
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Biology software promises easier way to program living cells

Biology software promises easier way to program living cells | Biocódices Blog | Scoop.it

'Cello' automates the fast, reliable design of DNA-based logic circuits.


Via Integrated DNA Technologies
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Living factories of the future

Living factories of the future | Biocódices Blog | Scoop.it

Scientists are designing cells that can manufacture drugs, food and materials [mdash] and even act as diagnostic biosensors. But first they must agree on a set of engineering tools.


Via Integrated DNA Technologies
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No designer babies, but gene editing to avoid disease? Maybe

No designer babies, but gene editing to avoid disease? Maybe | Biocódices Blog | Scoop.it
Don't expect designer babies any time soon—but a major new ethics report leaves open the possibility of one day altering human heredity to fight genetic diseases, with stringent oversight, using new tools that precisel
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New genetic engineering method indispensable biotechnological tool | Carl R. Woese Institute for Genomic Biology

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Why the FDA Wants More Control over Some Lab Tests 

Why the FDA Wants More Control over Some Lab Tests  | Biocódices Blog | Scoop.it
The FDA finds that many so-called laboratory-derived tests may actually harm patients
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Gut Microorganisms Affect Our Physiology

Gut Microorganisms Affect Our Physiology | Biocódices Blog | Scoop.it
Neuroscience News has recent neuroscience research articles, brain research news, neurology studies and neuroscience resources for neuroscientists, students, and science fans and is always free to join. Our neuroscience social network has science groups, discussion forums, free books, resources, science videos and more.
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Novel tool confers targeted, stable editing of epigenome in human stem cells - Salk Institute for Biological Studies

Novel tool confers targeted, stable editing of epigenome in human stem cells - Salk Institute for Biological Studies | Biocódices Blog | Scoop.it
LA JOLLA—Salk Institute scientists have developed a novel technology to correct disease-causing aberrations in the chemical tags on DNA that affect how genes are expressed. These types of chemical modifications, collectively referred to as epigenetics or the epigenome, are increasingly being considered as important as the genomic sequence itself in development and disease.
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Using CRISPR against cancer shows success in mice

Using CRISPR against cancer shows success in mice | Biocódices Blog | Scoop.it
CRISPR genome-editing technology could offer a new way to fight cancer, say researchers, who used it to target fusion genes in mice.
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Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics

Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics | Biocódices Blog | Scoop.it
The human microbiota greatly affects physiology and disease; however, the contribution of bacteria to the response to chemotherapeutic drugs remains poorly understood. Caenorhabditis elegans and its bacterial diet provide a powerful system to study host-bacteria interactions. Here, we use this system to study how bacteria affect the C. elegans response to chemotherapeutics. We find that different bacterial species can increase the response to one drug yet decrease the effect of another. We perform genetic screens in two bacterial species using three chemotherapeutic drugs: 5-fluorouracil (5-FU), 5-fluoro-2′-deoxyuridine (FUDR), and camptothecin (CPT). We find numerous bacterial nucleotide metabolism genes that affect drug efficacy in C. elegans. Surprisingly, we find that 5-FU and FUDR act through bacterial ribonucleotide metabolism to elicit their cytotoxic effects in C. elegans rather than by thymineless death or DNA damage. Our study provides a blueprint for characterizing the role of bacteria in the host response to chemotherapeutics.

Via Dominique Blanchard
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De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds

De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds | Biocódices Blog | Scoop.it
The Zika outbreak, spread by the Aedes aegypti mosquito, highlights the need to create high-quality assemblies of large genomes in a rapid and cost-effective fashion. Here, we combine Hi-C data with existing draft assemblies to generate chromosome-length scaffolds. We validate this method by assembling a human genome, de novo, from short reads alone (67X coverage). We then combine our method with draft sequences to create genome assemblies of the mosquito disease vectors Aedes aegypti and Culex quinquefasciatus , each consisting of three scaffolds corresponding to the three chromosomes in each species. These assemblies indicate that virtually all genomic rearrangements among these species occur within, rather than between, chromosome arms. The genome assembly procedure we describe is fast, inexpensive, accurate, and can be applied to many species.
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The ethical dilemma of designer babies | Paul Knoepfler

Creating genetically modified children is no longer a science fiction fantasy; it's a likely future scenario. Biologist Paul Knoepfler estimates that withi
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How early life experience is written into DNA

How early life experience is written into DNA | Biocódices Blog | Scoop.it
Moshe Szyf is a pioneer in the field of epigenetics, the study of how living things reprogram their genome in response to social factors like stress and lack of food. His research suggests that biochemical signals passed from mothers to offspring tell the child what kind of world they're going to live in, changing the expression of genes. "DNA isn't just a sequence of letters; it's not just a script." Szyf says. "DNA is a dynamic movie in which our experiences are being written."
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How the genomics revolution could finally help Africa

How the genomics revolution could finally help Africa | Biocódices Blog | Scoop.it
New investments promise to get precision medicine and precision public health off the ground. But experts debate how much work needs to be done first.
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Bio coding language makes it easier to hack living cells

Bio coding language makes it easier to hack living cells | Biocódices Blog | Scoop.it

Tinkering with life just got easier. A tool that lets you design DNA circuits using a simple symbolic language makes programming living cells as straightforward as writing code for computers.


Via Integrated DNA Technologies
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Synthetic Biology Explained

From selective breeding to genetic modification, our understanding of biology is now merging with the principles of engineering to bring us syntheti
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Day Two link with Johnson & Johnson on personalised microbiome analysis for diabetes nutrition

Day Two link with Johnson & Johnson on personalised microbiome analysis for diabetes nutrition | Biocódices Blog | Scoop.it
Gut microbiome analysis firm DayTwo will collaborate with Johnson & Johnson on personalised clinical nutrition for diabetes, and plans to open up its nutrition recommendation platform to new partners.
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Promising Discovery For A Non-Invasive Early Detection of Alzheimer’s

Promising Discovery For A Non-Invasive Early Detection of Alzheimer’s | Biocódices Blog | Scoop.it
Neuroscience News has recent neuroscience research articles, brain research news, neurology studies and neuroscience resources for neuroscientists, students, and science fans and is always free to join. Our neuroscience social network has science groups, discussion forums, free books, resources, science videos and more.
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Single Protein May Hold Secret to Treating Parkinson’s

Single Protein May Hold Secret to Treating Parkinson’s | Biocódices Blog | Scoop.it
Neuroscience News has recent neuroscience research articles, brain research news, neurology studies and neuroscience resources for neuroscientists, students, and science fans and is always free to join. Our neuroscience social network has science groups, discussion forums, free books, resources, science videos and more.
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