Autoimmunity
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Low doses of CMV induce autoimmune-mediated and inflammatory responses ... - Nature.com

“ Low doses of CMV induce autoimmune-mediated and inflammatory responses ...”
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Scientists Officially Link Processed Foods To Autoimmune Disease

Scientists Officially Link Processed Foods To Autoimmune Disease | Autoimmunity | Scoop.it
My tummy hurts me now when I eat processed foods since I have cut them from my daily diet. We had pizza Friday... http://t.co/477EpCKbMV
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Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell type specificity

Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell type specificity - up-to-the-minute news and headlines.
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Lymphocyte activation gene-3 (LAG-3, CD223) in plasmacytoid dendritic cells (pDCs): a molecular target for the restoration of active anti-tumor immunity

Lymphocyte activation gene-3 (LAG-3, CD223) in plasmacytoid dendritic cells (pDCs): a molecular target for the restoration of active anti-tumor immunity | Autoimmunity | Scoop.it
AbstractWe have recently reported that LAG-3 (CD223) mediates the alternative, IFNα-deficient activation of pDCs at tumor sites.
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New Discovery in Regulating Autoimmune Diseases | HMS

New research identifies in a natural molecule the potential to beat back autoimmune disease http://t.co/MRwGsMhVPa
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Frontiers | DQB1*06:02-Associated Pathogenic Anti-Myelin Autoimmunity in Multiple Sclerosis-Like Disease: Potential Function of DQB1*06:02 as a Disease-Predisposing Allele | Tumor Immunity

“ Susceptibility to Multiple Sclerosis (MS) has been linked mainly to the HLA-DRB1 locus, with the HLA-DR15 haplotype (DRB1*1501-DQA1*0102-DQB1*0602- DRB5*0101) dominating MS-risk in Caucasians. Alth...”
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1,25-Dihydroxyvitamin D3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes Patients

1,25-Dihydroxyvitamin D3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes Patients | Autoimmunity | Scoop.it
“ by Tom L. Van Belle, An-Sofie Vanherwegen, Dorien Feyaerts, Pierre De Clercq, Annemieke Verstuyf, Hannelie Korf, Conny Gysemans, Chantal Mathieu The emergence of regulatory T cells (Tregs) as central mediators of peripheral tolerance in the immune...”
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Tipping points in T-cell differentiation - LMU Munich

Tipping points in T-cell differentiation - LMU Munich | Autoimmunity | Scoop.it
#Researchers @LMU_Muenchen provide new insights in understanding the origins of #autoimmune disease http://t.co/EmPdFczecl #TH17
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Complement Component C5a Permits the Coexistence of Pathogenic Th17 Cells and Type I IFN in Lupus [AUTOIMMUNITY]

“ Systemic lupus erythematosus (SLE) is a type I IFN (IFN-I)–driven autoimmune disorder with exaggerated B and Th cell responses. Th17 cells, a recently identified Th cell subset, have been strongly implicated in the pathogenesis of SLE.”
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Krishan Maggon 's curator insight, September 22, 2014 12:56 AM
Published online before printAugust 22, 2014, doi:10.4049/jimmunol.1401322The Journal of ImmunologyOctober 1, 2014vol. 193 no. 7 3288-3295 Complement Component C5a Permits the Coexistence of Pathogenic Th17 Cells and Type I IFN in LupusSudesh Pawaria*, Kritika Ramani*, Kelly Maers*, Youhua Liu†, Lawrence P. Kane‡,Marc C. Levesque* and Partha S. Biswas*

+Author Affiliations

*Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261;†Division of Pathology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261; and‡Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261Address correspondence and reprint requests to Dr. Partha S. Biswas, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, BST S725, 3500 Terrace Street, Pittsburgh PA 15261. E-mail address: psb13@pitt.edu
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Intersection of population variation and autoimmunity genetics in human T cell activation

“ Two articles next to each other in @sciencemagazine relating to autoimmunity. http://t.co/iHrL7HzfAA & http://t.co/ajP0k8U2mI Interesting.”
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Association of cerebrospinal fluid anti-S... [Arthritis Res Ther. 2014] - PubMed - NCBI

“ PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.”
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Self DNA from Lymphocytes That Have Undergone Activation-Induced Cell Death Enhances Murine B Cell Proliferation and Antibody Production

Self DNA from Lymphocytes That Have Undergone Activation-Induced Cell Death Enhances Murine B Cell Proliferation and Antibody Production | Autoimmunity | Scoop.it
“ by Qing Lu, Ji-Yang Wang, Luman Wang, Xuechao Jiang, Yiwei Chu Systemic lupus erythematosus (SLE) is characterized by prominent autoinflammatory tissue damage associated with impaired removal of dying cells and DNA.”
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Innate Immunity in Systemic Sclerosis – Role of Toll-Like Receptors, Interferon, and the Potential Impact of Vitamin D - European Medical Journal

Innate Immunity in Systemic Sclerosis – Role of Toll-Like Receptors, Interferon, and the Potential Impact of Vitamin D - European Medical Journal | Autoimmunity | Scoop.it
“ The European Medical Journal (EMJ) is an open-access, peer-reviewed medical journal. Founded in 2012 as an imprint of Gorely New Media, the European Medical Journal provides reviews, symposiums and developments from Europe's medical congresses.”
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Meta-analysis of the TNFAIP3 region in psoriasis reveals a risk haplotype that ... - Nature.com

“ Meta-analysis of the TNFAIP3 region in psoriasis reveals a risk haplotype that ...”
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IGF-1 Could Suppress Immune System in Multiple Sclerosis, Other Autoimmune ... - Multiple Sclerosis News Today

IGF-1 Could Suppress Immune System in Multiple Sclerosis, Other Autoimmune ... - Multiple Sclerosis News Today | Autoimmunity | Scoop.it
Read About how IGF-1 Could Suppress Immune System in Multiple Sclerosis, Other Autoimmune Disease.
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Vestibular disorders in euthyroid patients with Hashimoto's thyroiditis: role of thyroid autoimmunity - Chiarella - 2014 - Clinical Endocrinology - Wiley Online Library

Vestibular disorders in euthyroid patients with Hashimoto's thyroiditis: role of thyroid autoimmunity - Chiarella - 2014 - Clinical Endocrinology - Wiley Online Library | Autoimmunity | Scoop.it
Suffering with Dizziness and loss of balance? Don't rule out this autoimmune thyroid disease! I see this everyday... http://t.co/2JA3blU7Ih
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Molecular map reveals genetic origins of 21 autoimmune diseases - Yale News

Molecular map reveals genetic origins of 21 autoimmune diseases - Yale News | Autoimmunity | Scoop.it
Scientists have created a molecular map that pinpoints genetic variants that play a role in 21 different autoimmune diseases, they report Oct. 27 in the journal Nature.
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Scientists prove link between viral infection and autoimmune disease

Scientists prove link between viral infection and autoimmune disease | Autoimmunity | Scoop.it
Common viral infections can pave the way to autoimmune disease, Australian scientists have revealed in breakthrough research published internationally today.
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Impact Analysis of Autoantibody Level and NR2 Antibody Level in Neuropsychiatric SLE Treated by Methylprednisolone Combined with MTX and DXM Intrathecal Injection - Springer

Impact Analysis of Autoantibody Level and NR2 Antibody Level in Neuropsychiatric SLE Treated by Methylprednisolone Combined with MTX and DXM Intrathecal Injection - Springer | Autoimmunity | Scoop.it
“ Impact Analysis of Autoantibody Level and NR2 Antibody Level in Neuropsychiatric SLE Treated by Me... http://t.co/NGWJvY96OQ #biophysics”
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Frontiers | DQB1*06:02-Associated Pathogenic Anti-Myelin Autoimmunity in Multiple Sclerosis-Like Disease: Potential Function of DQB1*06:02 as a Disease-Predisposing Allele | Tumor Immunity

“ Susceptibility to Multiple Sclerosis (MS) has been linked mainly to the HLA-DRB1 locus, with the HLA-DR15 haplotype (DRB1*1501-DQA1*0102-DQB1*0602- DRB5*0101) dominating MS-risk in Caucasians. Alth...”
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The Histidine Transporter SLC15A4 Coordinates mTOR-Dependent Inflammatory Responses and Pathogenic Antibody Production: Immunity

“ On the cover: Amino acid transporter SLC15A4 controls TLR7-induced autoantibody production http://t.co/YW4g1TZXsh http://t.co/QHjJn73oV8”
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Impaired mucosal immunity in patients with SLE - Nature.com

“ Impaired mucosal immunity in patients with SLE Nature.com In turn, microbial infections have been implicated as environmental factors that can influence autoimmune diseases in genetically predisposed individuals.”
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Gilbert C FAURE's curator insight, October 2, 2014 9:32 AM

A new study published this week in The Journal of Immunology identifies deficiencies in mucosal-associated invariant T (MAIT) cells from patients with systemic lupus erythematosus (SLE).

MAIT cells have an important function in mucosal immunity by protecting against mycobacterial and enterobacterial infections. In turn, microbial infections have been implicated as environmental…

  
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Meta-Analysis of Associations of IL1 Receptor Antagonist and Estrogen Receptor Gene Polymorphisms with Systemic Lupus Erythematosus Susceptibility

“ by Li Cai, Jin-wei Zhang, Xing-xin Xue, Zhi-gang Wang, Jia-jia Wang, Shai-di Tang, Shao-wen Tang, Jie Wang, Yun Zhang, Xian Xia Systemic lupus erythematosus (SLE) is an autoimmune disease that affects a number of different organs and tissues.”
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Krishan Maggon 's curator insight, October 8, 2014 6:19 AM

open access

 

PLoS One

 

OPEN ACCESS PEER-REVIEWEDRESEARCH ARTICLEMeta-Analysis of Associations of IL1 Receptor Antagonist and Estrogen Receptor Gene Polymorphisms with Systemic Lupus Erythematosus SusceptibilityLi Cai equal contributor,  Jin-wei Zhang equal contributor,  Xing-xin Xue,  Zhi-gang Wang,  Jia-jia Wang,  Shai-di Tang,  Shao-wen Tang,  Jie Wang,  Yun Zhang mail,  Xian Xia mail Published: October 06, 2014DOI: 10.1371/journal.pone.0109712

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Antiphospholipid Syndrome Novel Therapies - European Medical Journal

Antiphospholipid Syndrome Novel Therapies - European Medical Journal | Autoimmunity | Scoop.it
“ This article presents an overview of new pathogenetic mechanisms in antiphospholipid Syndrome as well as novel antithrombotic and immunomodulatory therapies”
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