APES Human Hazards 55
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APES Human Hazards 55
unit 6 pollution
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Climate Change VS. Disease

Is there a connection between climate change and infectious disease? Some scientists are sounding the alarm while others say it's not so bad.

 

Infection: invasion of the body by pathogenic microorganisms and their multiplication; leads to disease

 

Disease: an impairment of health or a condition of abnormal functioning

 

Pathogen: any disease-producing agent 

 

Vector: any agent that carries and trasnmits a disease

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More on dose-response analysis (threshold, acute effect, chronic effect)

More on dose-response analysis (threshold, acute effect, chronic effect) | APES Human Hazards 55 | Scoop.it

This graph represents a threshold agent, in which there is a dose where the substance leaves no measurable effects on the organism ( a non-threshold agent leaves measurable effects on the organism at any sort of exposure).

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Dose-Response Curve

Dose-Response Curve | APES Human Hazards 55 | Scoop.it

This basic dose-response curve represents the relationship between the concentration of the substance and the reaction of the organism. In the case of a toxin, generally as the concentration increases, the mortality also increases on an exponential scale.

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Risk Assessment (knowing) and Risk Management (doing)

Analyze your potential losses and make a decision on how to address the risk using your knowledge and judgement.

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ED50 vs. LD50

ED50 is the dose required to affect 50% of the population

LD50 is the dose required to kill 50% of the population

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TOXINS

TOXINS | APES Human Hazards 55 | Scoop.it

Toxin: a poisonous substance

 

Toxicity: the degree to which a subtstance is poisonous

 

What makes a compound harmful to humans?

1) dose: how much of the sunstance is taken in by the organism

2) exposure: how long the organism interacts with the substance

3) organism's size/age: direct relationship; a smaller organism extremely young or extremely old is much more likely to suffer from toxic substances

4) organism's ability to detoxify: organsim's ability to a return to a normal state after exposure to the toxin; also a direct relationship - if the ability to detoxify is low, the organism will suffer more

5) organsim's sensitivity: the tolerance of an organism to a toxin; similar to the ability to detoxify

6) synergistic effects: when the prescence of one chemical enhances the affects of another (ex: alcohol mixed with drugs)

 

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