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NMDA receptor structures reveal subunit arrangement and pore architecture

NMDA receptor structures reveal subunit arrangement and pore architecture | AntiNMDA | Scoop.it
X-ray crystal structures are presented of the N-methyl-d-aspartate (NMDA) receptor, a calcium-permeable ion channel that opens upon binding of glutamate and glycine; glutamate is a key excitatory neurotransmitter and enhanced structural insight of this receptor may aid development of therapeutic...
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Medicine and Me: Living with encephalitis: Dr Sarosh Irani & Dr Rachel Kneen

Lecture: What is being done to improve encephalitis for the future? Speakers: Dr Sarosh Irani, John Radcliffe Hospital, Oxford Dr Rachel Kneen, Alder Hey Chi...
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Know the red flags for synaptic autoimmune psychosis | MDedge Neurology

Know the red flags for synaptic autoimmune psychosis | MDedge Neurology | AntiNMDA | Scoop.it
antipsychotic agents make affected patients much worse, even to the point of developing something akin to neuroleptic malignant syndrome.
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World Encephalitis Day

World Encephalitis Day | AntiNMDA | Scoop.it
World Encephalitis Day is the global awareness day for people who have been directly or indirectly affected by encephalitis. Founded by The Encephalitis Society in the UK in 2014, it is held on February 22 each year and has reached over 80 million people in the past five years.
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Clinical manifestations, treatment outcomes, and prognostic factors of pediatric anti-NMDAR encephalitis in tertiary care hospitals: A multicenter ... - PubMed - NCBI

Clinical manifestations, treatment outcomes, and prognostic factors of pediatric anti-NMDAR encephalitis in tertiary care hospitals: A multicenter ... - PubMed - NCBI | AntiNMDA | Scoop.it
Brain Dev. 2019 Jan 10. pii: S0387-7604(18)30140-2. doi: 10.1016/j.braindev.2018.12.009.[Epub ahead of print]...
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AAN

AAN | AntiNMDA | Scoop.it
1. A score that predicts one year functional status in anti-NMDA receptor encephalitis patients. 2. [What's Trending]: Part 2: Drug pricing and the Institute for Clinical and Economic Review framework. In the first segment, Dr. David Lapides talks with Dr. Ramani Balu about his paper on a score that predicts one year functional status in anti-NMDA receptor encephalitis patients. In the second part of the podcast, you'll hear the the second part of Dr. Gordon Smith's interview with Dr. Steve Pearson on the Institute for Clinical and Economic Review and drug pricing. DISCLOSURES: Dr. David Lapides has served as a consultant for Boa Read More
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Scientists publish new findings on autoantibodies targeting synaptic proteins

Scientists publish new findings on autoantibodies targeting synaptic proteins | AntiNMDA | Scoop.it
New findings on autoantibodies targeting synaptic proteins have been recently published in Neuron and BRAIN journals by researchers from the Institute of...
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Forecasting outcomes in anti-NMDAR encephalitis

Forecasting outcomes in anti-NMDAR encephalitis | AntiNMDA | Scoop.it
“It's dangerous to make forecasts, especially about the future.” Mark Twain's words hold true in many situations in medicine, particularly in critical illnesses that carry both risk of death and the chance of full recovery, exemplified by autoimmune encephalitis.
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Mum 'possessed by evil spirits' is unable to walk or talk and suffers six seizures a day

Mum 'possessed by evil spirits' is unable to walk or talk and suffers six seizures a day | AntiNMDA | Scoop.it
Lorina Gutierrez was found to be suffering a rare illness causing her immune system to attack her brain...
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'Ask the Expert podcast series' on Autoimmune Encephalitis

'Ask the Expert podcast series' on Autoimmune Encephalitis | AntiNMDA | Scoop.it
Every month the Transverse Myelitis Association holds a podcast on a topic that affects those with rare neuro-immune disorders. Experts in the field share the latest knowledge and answer questions from their community.
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Frontiers | Characteristics of Seizure and Antiepileptic Drug Utilization in Outpatients With Autoimmune Encephalitis | Neurology

Frontiers | Characteristics of Seizure and Antiepileptic Drug Utilization in Outpatients With Autoimmune Encephalitis | Neurology | AntiNMDA | Scoop.it
Autoimmune encephalitis (AE) is a kind of encephalitis which associates with specific neuronal antigens. Most patients with AE likely suffer from seizure, but data on the characteristics of seizure and antiepileptic drugs (AEDs) utilization in this patient group remains limited.
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The Anti-NMDA Receptor Encephalitis Foundation Newsletter

The Anti-NMDA Receptor Encephalitis Foundation Newsletter | AntiNMDA | Scoop.it
A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis From...
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Japanese Encephalitis Virus-Induced Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report and Review of Literature. - PubMed - NCBI

Japanese Encephalitis Virus-Induced Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report and Review of Literature. - PubMed - NCBI | AntiNMDA | Scoop.it
Neuropediatrics. 2019 Jan 8. doi: 10.1055/s-0038-1675607.[Epub ahead of print]...
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A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis

A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis | AntiNMDA | Scoop.it
Objective To construct a grading score that predicts neurologic function 1 year after diagnosis of anti-NMDA receptor (NMDAR) encephalitis.

Methods Three hundred eighty-two patients with detailed information and functional status at 1 year were studied.
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RECOGNIZING PSYCHIATRIC PRESENTATIONS OF ANTI-NMDA RECEPTOR ENCEPHALITIS IN CHILDREN AND ADOLESCENTS: A SYNTHESIS OF PUBLISHED REPORTS. - PubMed - NCBI

RECOGNIZING PSYCHIATRIC PRESENTATIONS OF ANTI-NMDA RECEPTOR ENCEPHALITIS IN CHILDREN AND ADOLESCENTS: A SYNTHESIS OF PUBLISHED REPORTS. - PubMed - NCBI | AntiNMDA | Scoop.it
Psychiatry Clin Neurosci. 2019 Jan 17. doi: 10.1111/pcn.12821.[Epub ahead of print]...
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Rituximab in neurological disease: principles, evidence and practice

Rituximab in neurological disease: principles, evidence and practice | AntiNMDA | Scoop.it
Rituximab is a widely used B-cell-depleting monoclonal antibody. It is unlicensed for use in neurological disorders and there are no treatment guidelines. However, as a rapidly acting, targeted therapy with growing evidence of efficacy and tolerability in several neuroinflammatory disorders, it is...
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New type of encephalomyelitis responsive to trimethoprim/sulfamethoxazole treatment in Japan

New type of encephalomyelitis responsive to trimethoprim/sulfamethoxazole treatment in Japan | AntiNMDA | Scoop.it
Objective: To determine the causative pathogen and investigate the effective treatment of a new type of encephalomyelitis with an unknown pathogen in Japan and report the preliminary ultrastructural and genomic characterization of the causative agent.
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Anti-NMDAR encephalitis with concomitant varicella zoster virus detection and nonteratomatous malignancy

Anti-NMDAR encephalitis with concomitant varicella zoster virus detection and nonteratomatous malignancy | AntiNMDA | Scoop.it
A 50-year-old woman with a recent diagnosis of poorly differentiated nonteratomatous cervicouterine cancer presented to our hospital for breath-holding episodes resulting in perioral cyanosis. Her medical history was significant for chickenpox at age 8 and shingles at age 15.
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Working to Solve a Family’s Medical Mystery – Chan Zuckerberg Science Initiative –

The water in the Duke Children’s Hospital Pediatric Bone Marrow unit is ridiculously delicious. It has to be.The floor is full of children who have had their immune systems suppressed so their…...
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A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis

A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis | AntiNMDA | Scoop.it
Objective To construct a grading score that predicts neurologic function 1 year after diagnosis of anti-NMDA receptor (NMDAR) encephalitis.

Methods Three hundred eighty-two patients with detailed information and functional status at 1 year were studied.
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Clinical Reasoning: A middle-aged man with new onset seizures and myoclonic jerks

Clinical Reasoning: A middle-aged man with new onset seizures and myoclonic jerks | AntiNMDA | Scoop.it
A 53-year-old man with a history of hypertension presented with new-onset seizures. On the day of admission, he was witnessed by his son to have right-sided jerking that lasted for 1 minute, after which he fell forward and lost consciousness.
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HLA class II allele DRB1*16:02 is associated with anti-NMDAR encephalitis

Background and objective Aetiology and pathogenesis of anti- N -methyl-D-aspartate receptor (anti-NMDAR) encephalitis, the most common autoimmune encephalitis, is largely unknown. Since an association of the disease with the human leucocyte antigen (HLA) has not been shown so far, we here...
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Where the Amazing Story Began…

Where the Amazing Story Began… | AntiNMDA | Scoop.it
Dear Subscriber,
It has been nearly twelve years since the discovery of anti-NMDA receptor encephalitis and I never dreamed that I would become so fascinated with ...Read More...
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Diagnostic tools for immune causes of encephalitis. - PubMed - NCBI

Diagnostic tools for immune causes of encephalitis. - PubMed - NCBI | AntiNMDA | Scoop.it
Clin Microbiol Infect. 2018 Dec 21. pii: S1198-743X(18)30800-0. doi: 10.1016/j.cmi.2018.12.012.[Epub ahead of print] Review...
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Characteristics of Seizure and Antiepileptic Drug Utilization in Outpatients With Autoimmune Encephalitis | MyNeuroNews

Qi Huang, Meigang Ma, Xing Wei, Yuhan Liao, Hengchang Qi, Yuejuan Wu, Yuan Wu...
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Fundraiser by Cheryl Carew Martin : Hannah’s fight Against BRAIN ON FIRE

Fundraiser by Cheryl Carew Martin : Hannah’s fight Against BRAIN ON FIRE | AntiNMDA | Scoop.it
Cheryl Carew Martin needs your help today! Hannah’s fight Against BRAIN ON FIRE - This is our niece, sister,cousin ,friend and most importantly , daughter... sweet Hannah. 5 weeks ago Hannah experienced some simple memory loss.
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