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Immune disorder's symptoms mimic two mental illnesses

Immune disorder's symptoms mimic two mental illnesses | AntiNMDA | Scoop.it
When singer/songwriter/actor Demi Lovato was diagnosed with bipolar disorder at age 22, it came as a relief, and allowed her to deal with her condition. "When I focus on my treatment plan with my team and my support system, I'm able to not only maintain a healthy mind, but ... to maintain my sobriety."
Imagine, however, if you were diagnosed with that mental illness - for which there is no cure - when in fact you had a treatable immune disorder!
Back in 2007, researchers discovered that there was a form of immune encephalitis that affects specific brain receptor functions and triggers symptoms, such as paranoia and hearing voices, that are associated with bipolar disorder and with schizophrenia as well.
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Medicine and Me: Living with encephalitis: Dr Sarosh Irani & Dr Rachel Kneen

Lecture: What is being done to improve encephalitis for the future? Speakers: Dr Sarosh Irani, John Radcliffe Hospital, Oxford Dr Rachel Kneen, Alder Hey Chi...
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The Anti-NMDA Receptor Encephalitis Foundation Newsletter

The Anti-NMDA Receptor Encephalitis Foundation Newsletter | AntiNMDA | Scoop.it
Medicine and Me: Living with encephalitis: Dr Sarosh Irani & Dr Rachel Kneen From...
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Autoimmune Encephalitis and Rare Neuro-immune Disorders

Autoimmune Encephalitis and Rare Neuro-immune Disorders | AntiNMDA | Scoop.it
About Our Guest Speakers Michael Bradshaw, MD Neurologist at Billings Clinic and Assistant Professor of Neurology at Rosalind Franklin University of Medicine and Science Dr. Michael Bradshaw graduated from Mayo Clinic School of Medicine in Rochester, MN and went on to complete his neurology residency at Vanderbilt University. He completed additional training in multiple sclerosis and autoimmune neurology at Brigham and Women’s Hospital/Massachusetts General Hospital/Harvard Medical School. His practice and research focus on multiple sclerosis, autoimmune neurology, neurorheumatology, neuroinfectious disease and other rare neurologic diseases. Dr. Bradshaw and Dr. Sara Qureshi together run the only National Multiple Sclerosis Society Center for Comprehensive Care in Montana. He is an Assistant Professor of Neurology at Rosalind Franklin University of Medicine and Science, and he practices at the Billings Clinic in Billings, Montana. Tracey Cho, MD Director of Neuro-Immunology and Vice Chair for Education at University of Iowa Dr. Tracey Cho graduated from Yale School of Medicine and completed his neurology residency at Massachusetts General Hospital/Brigham and Women’s Hospital/Harvard Medical School. He obtained advanced training through a fellowship focused on autoimmune and infectious neurology. He co-directed the MGH autoimmune and infectious neurology program for several years, and recently joined the University of Iowa to be Director of Neuro-Immunology and Vice Chair for Education. His practice and research focus on autoimmune neurology including transverse myelitis, neurological infections and the overlap of rheumatology and neurology. Resources
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RECOGNIZING PSYCHIATRIC PRESENTATIONS OF ANTI-NMDA RECEPTOR ENCEPHALITIS IN CHILDREN AND ADOLESCENTS: A SYNTHESIS OF PUBLISHED REPORTS. - PubMed - NCBI

RECOGNIZING PSYCHIATRIC PRESENTATIONS OF ANTI-NMDA RECEPTOR ENCEPHALITIS IN CHILDREN AND ADOLESCENTS: A SYNTHESIS OF PUBLISHED REPORTS. - PubMed - NCBI | AntiNMDA | Scoop.it
Psychiatry Clin Neurosci. 2019 Jan 17. doi: 10.1111/pcn.12821.[Epub ahead of print]...
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Rituximab in neurological disease: principles, evidence and practice

Rituximab in neurological disease: principles, evidence and practice | AntiNMDA | Scoop.it
Rituximab is a widely used B-cell-depleting monoclonal antibody. It is unlicensed for use in neurological disorders and there are no treatment guidelines. However, as a rapidly acting, targeted therapy with growing evidence of efficacy and tolerability in several neuroinflammatory disorders, it is...
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New type of encephalomyelitis responsive to trimethoprim/sulfamethoxazole treatment in Japan

New type of encephalomyelitis responsive to trimethoprim/sulfamethoxazole treatment in Japan | AntiNMDA | Scoop.it
Objective: To determine the causative pathogen and investigate the effective treatment of a new type of encephalomyelitis with an unknown pathogen in Japan and report the preliminary ultrastructural and genomic characterization of the causative agent.
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Anti-NMDAR encephalitis with concomitant varicella zoster virus detection and nonteratomatous malignancy

Anti-NMDAR encephalitis with concomitant varicella zoster virus detection and nonteratomatous malignancy | AntiNMDA | Scoop.it
A 50-year-old woman with a recent diagnosis of poorly differentiated nonteratomatous cervicouterine cancer presented to our hospital for breath-holding episodes resulting in perioral cyanosis. Her medical history was significant for chickenpox at age 8 and shingles at age 15.
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Working to Solve a Family’s Medical Mystery – Chan Zuckerberg Science Initiative –

The water in the Duke Children’s Hospital Pediatric Bone Marrow unit is ridiculously delicious. It has to be.The floor is full of children who have had their immune systems suppressed so their…...
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A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis

A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis | AntiNMDA | Scoop.it
Objective To construct a grading score that predicts neurologic function 1 year after diagnosis of anti-NMDA receptor (NMDAR) encephalitis.

Methods Three hundred eighty-two patients with detailed information and functional status at 1 year were studied.
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Clinical Reasoning: A middle-aged man with new onset seizures and myoclonic jerks

Clinical Reasoning: A middle-aged man with new onset seizures and myoclonic jerks | AntiNMDA | Scoop.it
A 53-year-old man with a history of hypertension presented with new-onset seizures. On the day of admission, he was witnessed by his son to have right-sided jerking that lasted for 1 minute, after which he fell forward and lost consciousness.
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HLA class II allele DRB1*16:02 is associated with anti-NMDAR encephalitis

Background and objective Aetiology and pathogenesis of anti- N -methyl-D-aspartate receptor (anti-NMDAR) encephalitis, the most common autoimmune encephalitis, is largely unknown. Since an association of the disease with the human leucocyte antigen (HLA) has not been shown so far, we here...
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Where the Amazing Story Began…

Where the Amazing Story Began… | AntiNMDA | Scoop.it
Dear Subscriber,
It has been nearly twelve years since the discovery of anti-NMDA receptor encephalitis and I never dreamed that I would become so fascinated with ...Read More...
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Diagnostic tools for immune causes of encephalitis. - PubMed - NCBI

Diagnostic tools for immune causes of encephalitis. - PubMed - NCBI | AntiNMDA | Scoop.it
Clin Microbiol Infect. 2018 Dec 21. pii: S1198-743X(18)30800-0. doi: 10.1016/j.cmi.2018.12.012.[Epub ahead of print] Review...
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Belfast doctor who earned global reputation for treating epilepsy found he had condition himself

Belfast doctor who earned global reputation for treating epilepsy found he had condition himself | AntiNMDA | Scoop.it
Stoical Jim Morrow flags up the irony early on in the conversation.For the twist in the tale of this hugely respected 62-year-old consultant neurologist is that he had to take early re...
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Encephalitis with anti-NMDA receptor antibodies: paraneoplastic or non-paraneoplastic? - PubMed - NCBI

Encephalitis with anti-NMDA receptor antibodies: paraneoplastic or non-paraneoplastic? - PubMed - NCBI | AntiNMDA | Scoop.it
Neuro Endocrinol Lett. 2018 Dec 22;39(5):351-354.[Epub ahead of print]...
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Frontiers | Hippocampus and Insula Are Targets in Epileptic Patients With Glutamic Acid Decarboxylase Antibodies | Neurology

Frontiers | Hippocampus and Insula Are Targets in Epileptic Patients With Glutamic Acid Decarboxylase Antibodies | Neurology | AntiNMDA | Scoop.it
Antibodies to glutamic acid decarboxylase (GAD ab) have been found in patients with limbic encephalitis (LE) and chronic pharmacoresistant focal epilepsy (FE). The objectives of the study were: 1) analyze the clinical and neuroimaging course of patients with FE+GAD ab, 2) compare these...
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Know the red flags for synaptic autoimmune psychosis | MDedge Neurology

Know the red flags for synaptic autoimmune psychosis | MDedge Neurology | AntiNMDA | Scoop.it
antipsychotic agents make affected patients much worse, even to the point of developing something akin to neuroleptic malignant syndrome.
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World Encephalitis Day

World Encephalitis Day | AntiNMDA | Scoop.it
World Encephalitis Day is the global awareness day for people who have been directly or indirectly affected by encephalitis. Founded by The Encephalitis Society in the UK in 2014, it is held on February 22 each year and has reached over 80 million people in the past five years.
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Clinical manifestations, treatment outcomes, and prognostic factors of pediatric anti-NMDAR encephalitis in tertiary care hospitals: A multicenter ... - PubMed - NCBI

Clinical manifestations, treatment outcomes, and prognostic factors of pediatric anti-NMDAR encephalitis in tertiary care hospitals: A multicenter ... - PubMed - NCBI | AntiNMDA | Scoop.it
Brain Dev. 2019 Jan 10. pii: S0387-7604(18)30140-2. doi: 10.1016/j.braindev.2018.12.009.[Epub ahead of print]...
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AAN

AAN | AntiNMDA | Scoop.it
1. A score that predicts one year functional status in anti-NMDA receptor encephalitis patients. 2. [What's Trending]: Part 2: Drug pricing and the Institute for Clinical and Economic Review framework. In the first segment, Dr. David Lapides talks with Dr. Ramani Balu about his paper on a score that predicts one year functional status in anti-NMDA receptor encephalitis patients. In the second part of the podcast, you'll hear the the second part of Dr. Gordon Smith's interview with Dr. Steve Pearson on the Institute for Clinical and Economic Review and drug pricing. DISCLOSURES: Dr. David Lapides has served as a consultant for Boa Read More
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Scientists publish new findings on autoantibodies targeting synaptic proteins

Scientists publish new findings on autoantibodies targeting synaptic proteins | AntiNMDA | Scoop.it
New findings on autoantibodies targeting synaptic proteins have been recently published in Neuron and BRAIN journals by researchers from the Institute of...
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Forecasting outcomes in anti-NMDAR encephalitis

Forecasting outcomes in anti-NMDAR encephalitis | AntiNMDA | Scoop.it
“It's dangerous to make forecasts, especially about the future.” Mark Twain's words hold true in many situations in medicine, particularly in critical illnesses that carry both risk of death and the chance of full recovery, exemplified by autoimmune encephalitis.
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Mum 'possessed by evil spirits' is unable to walk or talk and suffers six seizures a day

Mum 'possessed by evil spirits' is unable to walk or talk and suffers six seizures a day | AntiNMDA | Scoop.it
Lorina Gutierrez was found to be suffering a rare illness causing her immune system to attack her brain...
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'Ask the Expert podcast series' on Autoimmune Encephalitis

'Ask the Expert podcast series' on Autoimmune Encephalitis | AntiNMDA | Scoop.it
Every month the Transverse Myelitis Association holds a podcast on a topic that affects those with rare neuro-immune disorders. Experts in the field share the latest knowledge and answer questions from their community.
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Frontiers | Characteristics of Seizure and Antiepileptic Drug Utilization in Outpatients With Autoimmune Encephalitis | Neurology

Frontiers | Characteristics of Seizure and Antiepileptic Drug Utilization in Outpatients With Autoimmune Encephalitis | Neurology | AntiNMDA | Scoop.it
Autoimmune encephalitis (AE) is a kind of encephalitis which associates with specific neuronal antigens. Most patients with AE likely suffer from seizure, but data on the characteristics of seizure and antiepileptic drugs (AEDs) utilization in this patient group remains limited.
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