Vitae Herbae (her...
Follow
Find tag "herbal"
2.7K views | +0 today
Vitae Herbae (herbal, natural, integrative medicine  & health)
web-based scientific information on natural medicine
Your new post is loading...
Your new post is loading...
Scooped by Pasquale Valente
Scoop.it!

Herbal Medicine Alters Genes, Cell Mitosis and Epigenome

Herbal Medicine Alters Genes, Cell Mitosis and Epigenome | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it
Genetics researchers have determined that over a third of herbal medicines used in Traditional Chinese Medicine - and nearly all leading therapeutic herbs - alter our genes or alter enzymes that alter our genetic material.
Pasquale Valente's insight:

TCM prescriptions’ modulation of the human epigenome helps elucidation of phyto-pharmacology and discovery of epigenetic drugs. Furthermore, as TCM medicinals’ properties are closely tied to patient TCM syndromes, results of this materia-medica-wide, bioinformatic analysis of TCM medicinals may have implications for molecular differentiation of TCM syndromes.


Histone modifications and traditional Chinese medicinals   http://www.biomedcentral.com/1472-6882/13/115



more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Towards polypharmacokinetics: pharmacokinetics of multicomponent drugs and herbal medicines using a metabolomics approach. [Evid Based Complement Alternat Med. 2013] - PubMed - NCBI

Towards polypharmacokinetics: pharmacokinetics of multicomponent drugs and herbal medicines using a metabolomics approach. [Evid Based Complement Alternat Med. 2013] - PubMed - NCBI | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it

 This paper discusses recent advances in the characterization of poly-PK and the metabolism of multicomponent xenobiotic agents, such as compound drugs, dietary supplements, and herbal medicines, using metabolomics strategy.

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Analysis of herbal products shows contamination is common

Most herbal products, available to buy as alternative medicines, may be contaminated. Researchers demonstrate the presence of contamination and substitution of plant species in a selection of herbal products using DNA barcoding.
Pasquale Valente's insight:

"The results showed that 59% of the products contained plant species not listed on the labels. Over two thirds of the products tested had plant species present which were a substitution for the plants listed on the label and a third of products also contained other species that may be a filler or contamination."

more...
No comment yet.
Rescooped by Pasquale Valente from A Tale of Two Medicines
Scoop.it!

America's Largest Professional Society of Medicinal Plant Research Experts Endorses Botanical Adulteration Education Program

America's Largest Professional Society of Medicinal Plant Research Experts Endorses Botanical Adulteration Education Program | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it

The American Society of Pharmacognosy (ASP) has announced its endorsement of the ABC-AHP-NCNPR Botanical Adulterants Program. This is an educational program designed to increase the herb, dietary supplements, and natural products industries' awareness of the need for enhanced scrutiny via laboratory analysis of herbal raw materials, extracts, and essential oils that may be accidentally or purposefully adulterated with lower-cost, non-disclosed ingredients. The Program is headed by three nonprofit groups focused on research and education on medical herbs and other beneficial plants: the American Botanical Council (ABC), the American Herbal Pharmacopoeia (AHP), and the National Center for Natural Products Research (NCNPR) at the University of Mississippi.

 

ASP is North America's leading organization of scientists involved with research on medicinal plants, fungi, marine organisms, and other natural materials used in the production of new medicines, comprising the essence of the science of pharmacognosy. Founded in 1959, ASP consists of more than 1,100 pharmacognosists, natural products chemists, botanists, molecular biologists, and other medicinal plant research experts from around the world.

 

Bradley Moore, PhD, president of ASP and a professor at the Scripps Institution of Oceanography at the University of California at San Diego, wrote in a letter to American Botanical Council Founder and Executive Director Mark Blumenthal,


Via Jonathan Middleton
more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Bioavailability enhancers of herbal origin: An overview

Bioavailability enhancers of herbal origin: An overview | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it

Abstract

Recently, the use of herbal medicines has been increased all over the world due to their therapeutic effects and fewer adverse effects as compared to the modern medicines. However, many herbal drugs and herbal extracts despite of their impressive in-vitro findings demonstrates less or negligible in-vivo activity due to their poor lipid solubility or improper molecular size, resulting in poor absorption and hence poor bioavailability. Nowadays with the advancement in the technology, novel drug delivery systems open the door towards the development of enhancing bioavailability of herbal drug delivery systems. For last one decade many novel carriers such as liposomes, microspheres, nanoparticles, transferosomes, ethosomes, lipid based systems etc. have been reported for successful modified delivery of various herbal drugs. Many herbal compounds including quercetin, genistein, naringin, sinomenine, piperine, glycyrrhizin and nitrile glycoside have demonstrated capability to enhance the bioavailability. 

Pasquale Valente's insight:

"The objective of this review is to summarize various available novel drug delivery technologies which have been developed for delivery of drugs (herbal), and to achieve better therapeutic response. An attempt has also been made to compile a profile on bioavailability enhancers of herbal origin with the mechanism of action (wherever reported) and studies on improvement in drug bioavailability, exhibited particularly by natural compounds."


more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Herbal Therapies for Type 2 Diabetes Mellitus: Chemistry, Biology, and Potential Application of Selected Plants and Compounds

Abstract

Diabetes mellitus has been recognized since antiquity. It currently affects as many as 285 million people worldwide and results in heavy personal and national economic burdens. Considerable progress has been made in orthodox antidiabetic drugs. However, new remedies are still in great demand because of the limited efficacy and undesirable side effects of current orthodox drugs. Nature is an extraordinary source of antidiabetic medicines. To date, more than 1200 flowering plants have been claimed to have antidiabetic properties. Among them, one-third have been scientifically studied and documented in around 460 publications. In this review, we select and discuss blood glucose-lowering medicinal herbs that have the ability to modulate one or more of the pathways that regulate insulin resistance, -cell function, GLP-1 homeostasis, and glucose (re)absorption. Emphasis is placed on phytochemistry, anti-diabetic bioactivities, and likely mechanism(s). Recent progress in the understanding of the biological actions, mechanisms, and therapeutic potential of compounds and extracts of plant origin in type 2 diabetes is summarized. This review provides a source of up-to-date information for further basic and clinical research into herbal therapy for type 2 diabetes. Emerging views on therapeutic strategies for type 2 diabetes are also discussed.


Pasquale Valente's insight:

Based on safety and their multiple targeting actions, herbal therapies are potent therapeutic means in T2D. The chemistry and biology of nearly 40 extracts and compounds of plant origin that have been demonstrated to prevent and treat T2D via the regulation of insulin resistance, beta-cell function, incretin pathways, and glucose (re)absorption are here summarized. 

http://world.einnews.com/article/169809253/k6cJpDxF_lvhkh8X

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy ? [Evid Based Complement Alternat Med. 2013] - PubMed - NCBI

Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy ? [Evid Based Complement Alternat Med. 2013] - PubMed - NCBI | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it

Abstract

Chemotherapy-induced neuropathy (CIPN) has a relevant impact on the quality of life of cancer patients. There are no curative conventional treatments, so further options have to be investigated. We conducted a systematic review in English and Chinese language databases to illuminate the role of medical herbs. 26 relevant studies on 5 single herbs, one extract, one receptor-agonist, and 8 combinations of herbs were identified focusing on the single herbs Acorus calamus rhizoma, Cannabis sativa fructus, Chamomilla matricaria, Ginkgo biloba, Salvia officinalis, Sweet bee venom, Fritillaria cirrhosae bulbus, and the herbal combinations Bu Yang Huan Wu, modified Bu Yang Huan Wu plus Liuwei Di Huang, modified Chai Hu Long Gu Mu Li Wan, Geranii herba plus Aconiti lateralis praeparata radix , Niu Che Sen Qi Wan (Goshajinkigan), Gui Zhi Jia Shu Fu Tang (Keishikajutsubuto), Huang Qi Wu Wu Tang (Ogikeishigomotsuto), and Shao Yao Gan Cao Tang (Shakuyakukanzoto). The knowledge of mechanism of action is still limited, the quality of clinical trials needs further improvement, and studies have not yielded enough evidence to establish a standard practice, but a lot of promising substances have been identified. While CIPN has multiple mechanisms of neuronal degeneration, a combination of herbs or substances might deal with multiple targets for the aim of neuroprotection or neuroregeneration in CIPN

Pasquale Valente's insight:

"Experimental and clinical studies have not yielded enough evidence to establish a standard practice for the treatment of CIPN, but from this literature review, a lot of promising substances, mainly Chinese medical herbs with possible effect in CIPN or a putative influence on mechanisms of CIPN, have been identified in the last years."

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747437/ 

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Chinese herbal medicine for atopic eczema. [Cochrane Database Syst Rev. 2013] - PubMed - NCBI

Abstract

BACKGROUND:

Chinese herbal medicine (CHM) has been increasingly used for atopic eczema. A previous version of this Cochrane review published in 2004 found some evidence of a possible benefit for oral ingestion of CHM for eczema, but the results were inconclusive and the evidence needs to be updated. We have expanded the scope of this review to include an assessment of the topical and oral effects of CHM for eczema.

OBJECTIVES:

To assess the effects of oral ingestion and topical applications of CHM for the management of eczema in children and adults.

AUTHORS' CONCLUSIONS:

We could not find conclusive evidence that CHM taken by mouth or applied topically to the skin could reduce the severity of eczema in children or adults.Well-designed, adequately powered RCTs are needed to evaluate the efficacy and safety of CHM for managing eczema.

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

The Antiinflammatory Mechanism of Igongsan in Mouse Peritoneal Macrophages via Suppression of NF-κB/Caspase-1 Activation. [Phytother Res. 2013] - PubMed - NCBI

The Antiinflammatory Mechanism of Igongsan in Mouse Peritoneal Macrophages via Suppression of NF-κB/Caspase-1 Activation. [Phytother Res. 2013] - PubMed - NCBI | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it

Abstract

Igongsan (IGS), which is an herbal prescription composed of five different herbs, Ginseng Radix (root of Panax ginseng, Araliaceae), Atractylodis Rhizoma Alba (rhizome of Atractylodes Macrocephala, Compositae), Poria Sclerotium (sclerotium of Poria cocos, Polyporaceae), Glycyrrhizae Radix et Rhizoma (root and rhizome of Glycyrrhiza uralensis, Leguminosae), and Citri Unshius Pericarpium (Peel of Citrus unshiu, Rutaceae), has been traditionally used in Korea to treat a variety of inflammatory diseases. In this study, we investigated to elucidate the mechanism responsible for IGS's antiinflammatory effect in mouse peritoneal macrophages. The findings demonstrate that IGS inhibited the production of inflammatory cytokine and prostaglandins E2 . IGS inhibited the enhanced levels of cyclooxygenase-2 and inducible NO synthase caused by lipopolysaccharide (LPS). Additionally, it was shown that the antiinflammatory effect of IGS is through regulating the activation of nuclear factor-kappa B and caspase-1 in LPS-stimulated mouse peritoneal macrophages. These results provide novel insights into the pharmacological actions of IGS as a potential candidate for development of new drugs to treat inflammatory diseases. Discussion and conclusion: These results provide novel insights into the pharmacological actions of IGS as a potential candidate for development of new drugs to treat inflammatory diseases. Copyright © 2013 John Wiley & Sons, Ltd.

Pasquale Valente's insight:

 The findings demonstrate that IGS inhibited the production of inflammatory cytokine and prostaglandins E2 . IGS inhibited the enhanced levels of cyclooxygenase-2 and inducible NO synthase caused by lipopolysaccharide (LPS). Additionally, it was shown that the antiinflammatory effect of IGS is through regulating the activation of nuclear factor-kappa B and caspase-1

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Systematic review: the efficacy of herbal therapy in inflammatory bowel disease.[Aliment Pharmacol Ther. 2013] - PubMed - NCBI

.

Pasquale Valente's insight:

Randomised controlled trials of herbal therapy for the treatment of IBD show encouraging results but studies remain limited and heterogenous. 

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Traditional Chinese medicine: a promising candidate for the treatment of Alzheimer's disease.

Pasquale Valente's insight:

Latest research progress on TCM showing their possible role of treatment of AD and other demented diseases and possible pharmacological actions

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

In vitro: The effect of aqueous cinnamon extract on the apoptotic process in acute myeloid leukemia HL-60 cells.

A
Pasquale Valente's insight:

Cinnamon extract inhibited the growth of HL-60 cells as correlated with concentration and time.

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Broccoli may trump genetics when it comes to arthritis

Broccoli may trump genetics when it comes to arthritis | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it
More than one in five Irish people have some form of the disease
more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-Yin. [Evid Based Complement Alternat Med. 2013] - PubMed - NCBI

An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-Yin. [Evid Based Complement Alternat Med. 2013] - PubMed - NCBI | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it
Pasquale Valente's insight:

results demonstrated the synergistic effects among the four herbs of QLY. The predictions also include the mechanisms of decreased toxicity of Zuo and Shi herb in QLY

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Vitae Herbae

Vitae Herbae | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it
Vitae Herbae , by pasquale valente: herbal medicine and natural prevention of diseases
more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Pharmacosomes: An Emerging Novel Vesicular Drug Delivery System for Poorly Soluble Synthetic and Herbal Drugs. [ISRN Pharm. 2013] - PubMed - NCBI

Abstract

In the arena of solubility enhancement, several problems are encountered. A novel approach based on lipid drug delivery system has evolved, pharmacosomes. Pharmacosomes are colloidal, nanometric size micelles, vesicles or may be in the form of hexagonal assembly of colloidal drug dispersions attached covalently to the phospholipid. They act as befitting carrier for delivery of drugs quite precisely owing to their unique properties like small size, amphiphilicity, active drug loading, high entrapment efficiency, and stability. They help in controlled release of drug at the site of action as well as in reduction in cost of therapy, drug leakage and toxicity, increased bioavailability of poorly soluble drugs, and restorative effects. There has been advancement in the scope of this delivery system for a number of drugs used for inflammation, heart diseases, cancer, and protein delivery along with a large number of herbal drugs. Hence, pharmacosomes open new challenges and opportunities for improved novel vesicular drug delivery system.

Pasquale Valente's insight:

"Vesicular systems are the emerging carrier systems in the pharmaceutical industry"

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Chinese Herbal Medicine

Chinese Herbal Medicine | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it
I’m often asked about Chinese herbal medicine.  I use herbal formulas for patients, when needed, and they wonder how these formulas are different from herbs you purchase at health food markets and...
more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Activate Your Longevity Genes: Five Natural Compounds Simulate Caloric Restriction - 2 - Life Extension

Activate Your Longevity Genes: Five Natural Compounds Simulate Caloric Restriction - 2 - Life Extension | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it
Modern science has only recently begun to unravel the mystery behind how calorie restriction extends life span and improves overall health. Most people, however, find it difficult to sufficiently reduce the amount of food they consume.
Pasquale Valente's insight:

"The unique ability of these nutrients to modulate gene expression exerts system-wide effects that, in addition to influencing many of the same pathways activated by calorie restriction, can also significantly reduce degenerative disease risk."

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Advances in Neuroprotective Ingredients of Medicinal Herbs by Using Cellular and Animal Models of Parkinson's Disease. [Evid Based Complement Alternat Med. 2013] - PubMed - NCBI

Abstract

Parkinson's disease (PD) is a multifactorial disorder, which is neuropathologically identified by age-dependent neurodegeneration of dopaminergic neurons in the substantia nigra. Development of symptomatic treatments has been partly successful for PD research, but there remain a number of inadequacies in therapeutic strategies for the disease. The pathogenesis of PD remains intricate, and the present anti-PD treatments appears to be clinically insufficient. Comprehensive research on discovery of novel drug candidates has demonstrated that natural products, such as medicinal herbs, plant extracts, and their secondary metabolites, have great potential as therapeutics with neuroprotective activity in PD. Recent preclinical studies suggest that a number of herbal medicines and their bioactive ingredients can be developed into optimum pharmaceuticals for treating PD. In many countries, traditional herbal medicines are used to prevent or treat neurodegenerative disorders, and some have been developed as nutraceuticals or functional foods. Here we focus on recent advances of the evidence-linked neuroprotective activity of bioactive ingredients of herbal origin in cellular and animal models of PD research.

Pasquale Valente's insight:

"Bioactive constituents listed in this current write-up belong to different chemical classes like including, Terpenes (ginsenoside Rg1, tenuigenin, astragaloside IV), flavones (puerarin, luteolin and baicalein, morin), stilbenoids (resveratrol), phenylpropanoid (echinacoside), phenylethyl glycoside (acteoside), coumarin (umbelliferone and esculetin), and catechol (curcumin and protocatechuic acid).  All the mentioned bioactive compounds have demonstrated a significant neuroprotective effect in PD models. "

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan

Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it

A total of 108,362 patients had diagnosis of asthma at least once during 1997–2009, and a total of 401,149 ambulatory visits were made. 69,879 visits were made by the children aged from six to eighteen. Additionally, a total of 24,650 CHM prescriptions could be extracted for further analysis (Figure 1). In average, each prescription was composed of 4.2 CHM, and TCM physicians usually used up to three to four CHM in one prescription (Figure 2).

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Hepatotoxic Botanicals - An Evidence-based Systematic Review. [J Pharm Pharm Sci. 2013] - PubMed - NCBI

Abstract

Purpose. Herbal medicines have been increasingly used worldwide. However, the potential harms of these herbs have been noticed most recently following hepatotoxicity with ingestion of herbal remedies. The aim of this review is to evaluate the evidence of hepatotoxic effects linked to use ofherbal preparations. Method. Electronic search was performed by searching several databases: PubMed, HerbMed, Google Scholar, Scopus, Cochrane Database of Systematic Reviews and Cochrane Library using both Latin and common names of several herbs. Language was restricted to English and articles were selected for relevance reporting incidence of hepatotoxicity associated with use of herbal products in human. Results. From a total of 565 relevant reviews and articles, 254 met our inclusion criteria and were analyzed. Serious hepatotoxic events associated with variousherbal products alone or in combination with other drugs have been reported. Linking to herbal constituents the spectrum of liver toxicity includes elevated liver enzymes, acute or chronic hepatitis, cholestasis, hepatic necrosis, fibrosis, and cirrhosis, as well as acute liver failure and hepatic veno-occlusive disease. Conclusion. The hepatotoxicity of herbs was extensively acknowledged. As the use of natural medicine increases, the risk of liver toxicity and drug interaction increase as well. Accordingly, herbal remedies have been known as hepatotoxins causing several liver damages. Further scientific studies with high and good quality are needed to identify toxic compounds and understand the exact mechanism of hepatotoxicity-induced by herbs. The adverse effects of herbal products must be fully reported as well as extensive education of healthcare providers must be provided in order to reduce danger of alternative medicines. 

Pasquale Valente's insight:

"This article is open to POST-PUBLICATION REVIEW. Registered readers (see "For Readers") may comment by clicking on ABSTRACT on the issue's contents page."


http://ejournals.library.ualberta.ca/index.php/JPPS/article/view/17973/15135

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.

Sarris JMcIntyre ECamfield DA.

A search of MEDLINE (PubMed), CINAHL, Scopus and the Cochrane Library databases was conducted (up to 28 October 2012) for English language papers using the search terms 'anxiety' OR 'anxiety disorder' OR 'generalized anxiety disorder' OR 'social phobia' OR 'post-traumatic stress disorder' OR 'panic disorder' OR 'agoraphobia' OR 'obsessive compulsive disorder' in combination with the search terms 'Herb*' OR 'Medicinal Plants' OR 'Botanical Medicine' OR 'Chinese herb*', in addition to individual herbal medicines. This search of the literature revealed 1,525 papers, of which 53 plants were included in the review (having at least one study using the whole plant extract).

Pasquale Valente's insight:

"Support for efficacy was found for chronic use (i.e. greater than one day) of the following herbs in treating a range of anxiety disorders in human clinical trials: Piper methysticum, Matricaria recutita, Ginkgo biloba, Scutellaria lateriflora, Silybum marianum, Passiflora incarnata, Withania somniferum, Galphimia glauca, Centella asiatica, Rhodiola rosea, Echinacea spp., Melissa officinalis and Echium amoenum."

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Antidiabetic, Antihyperlipidemic and Antioxidant Activities of a Novel Proteoglycan from Ganoderma Lucidum Fruiting Bodies on db/db Mice and the Possible Mechanism. [PLoS One. 2013] - PubMed - NCBI

Antidiabetic, Antihyperlipidemic and Antioxidant Activities of a Novel Proteoglycan from Ganoderma Lucidum Fruiting Bodies on db/db Mice and the Possible Mechanism. [PLoS One. 2013] - PubMed - NCBI | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it

Abstract

Previously, we screened a proteoglycan for anti-hyperglycemic, named FYGL, from Ganoderma Lucidum. For further research of the antidiabetic mechanisms of FYGL in vivo, the glucose homeostasis, activities of insulin-sensitive enzymes, glucose transporter expression and pancreatic function were analyzed using db/db mice as diabetic models in the present work. FYGL not only lead to a reduction in glycated hemoglobin level, but also an increase in insulin and C-peptide level, whereas a decrease in glucagons level and showed a potential for the remediation of pancreatic islets. FYGL also increased the glucokinase activities, and simultaneously lowered the phosphoenol pyruvate carboxykinase activities, accompanied by a reduction in the expression of hepatic glucose transporter protein 2, while the expression of adipose and skeletal glucose transporter protein 4 was increased. Moreover, the antioxidant enzyme activities were also increased by FYGL treatment. Thus, FYGL was an effective antidiabetic agent by enhancing insulin secretion and decreasing hepatic glucose output along with increase of adipose and skeletal muscle glucose disposal in the late stage of diabetes. Furthermore, FYGL is beneficial against oxidative stress, thereby being helpful in preventing the diabetic complications.

more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Vitae Herbae

Vitae Herbae | Vitae Herbae (herbal, natural, integrative medicine  & health) | Scoop.it
Vitae Herbae , by pasquale valente: herbal medicine and natural prevention of diseases
more...
No comment yet.
Scooped by Pasquale Valente
Scoop.it!

Toxicity evaluation of standardized extract of Gynostemma pentaphyllum Makino.

A
Pasquale Valente's insight:

Standardized extract of Gynostemma pentaphyllum did not cause death or any toxic signs in rats. The daily administration of the extract for 90 days did not produce lethal or harmful effects. 

more...
No comment yet.