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Ebola outbreak: Five co-authors of latest study killed by virus before their research was published

Ebola outbreak: Five co-authors of latest study killed by virus before their research was published | Virology News | Scoop.it
Five co-authors of the latest study on Ebola were killed by the virus before their research was published, highlighting the huge risks undertaken by those working to combat its spread.
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That is what you could call a sobering thought - and highlights how disproportionately the virus hits healthcare workers.

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like zombies B-)
Curated by Ed Rybicki
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Polymeric micro/nanoparticles: Particle design and potential vaccine delivery applications

Polymeric micro/nanoparticles: Particle design and potential vaccine delivery applications | Virology News | Scoop.it
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Yellow fever: the resurgence of a forgotten disease

The possibility that a mosquito bite during pregnancy could cause severe brain damage in newborn babies has alarmed the public and astonished scientists. The Zika outbreak in the Americas shows how a disease that slumbered for six decades in Africa and Asia, never causing an outbreak, can become a global health emergency. The Ebola and Zika outbreaks have revealed gaping holes in our lines of defence: weak health infrastructures and capacities in west Africa and the demise of programmes for mosquito control in the Americas. Both outbreaks show how old diseases can behave in surprising ways when they invade new territory.
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Bacterially produced single-shot modular virus-like particle capsomere vaccine for avian influenza

Bacterially produced single-shot modular virus-like particle capsomere vaccine for avian influenza | Virology News | Scoop.it
Ed Rybicki's insight:
I note their crudely-purified version was better than their purified: why are we so obsessed with molecular purity??
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Zika crisis: WHO rejects 'move Rio Olympics' call

Zika crisis: WHO rejects 'move Rio Olympics' call | Virology News | Scoop.it
More than 100 leading scientists say the Rio Olympics should be moved or postponed due to the Zika outbreak - but the World Health Organization rejects this.
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Why Nigeria should be worried about the arrival of Zika virus and Yellow fever 

Why Nigeria should be worried about the arrival of Zika virus and Yellow fever  | Virology News | Scoop.it
RT @GistTodayNG: Why Nigeria should be worried about the arrival of Zika virus&Yellow fever on the continent. https://t.co/wNMNZIh46p https…
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England To Offer Gay Men HPV Vaccine For First Time

England To Offer Gay Men HPV Vaccine For First Time | Virology News | Scoop.it
RT @scifeeds: England To Offer Gay Men HPV Vaccine For First Time https://t.co/eLMhWBji7X https://t.co/qdPx2zsGxV
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5.7m Nigerians living with HIV/AIDS 

5.7m Nigerians living with HIV/AIDS  | Virology News | Scoop.it
ABUJA—FORMER African Presidents, under the aegis of Champions for an AIDS-Free Generation in Africa, yesterday said over 3.4 per cent of Nigerians were currently living with the dreaded HIV/AIDS. With the percentage put forward by the ex- presidents, about 5.7 million of Nigeria’s 170 million are currently infected with the virus. The figures were revealed by both the former President of Botswana, Festus Mogae and ex- Vice President of Uganda, Speciosa Wandira, when they paid a courtesy call on President of the Senate, Senator Bukola Saraki. Speaking earlier, former President of Botswana, Festus Mogae, who disclosed that the group, Champions for an AIDS- free Generation was formed to harmonize their experiences as past African leaders to collectively fight the disease, said in Nigeria, those infected with HIV and AIDS stood at three percent, meaning that the figure translated to 5.7 million Nigerians. Mogae, who stressed the need for coordinated efforts by the executive and the legislature to ensure that resources were made available to nip the disease in the bud, added that with the present HIV/ AIDS status of the country, Nigeria was next to South Africa. He said: “As you have been told, we are a group of former presidents, including your own Obasanjo. We dealt with the scourge when it broke out and from our experience, we realized that we didn’t stabilize the situation until the top leadership was involved and by the time some of us left office, we helped stabilize the situation. ‘’We had attained some levels of success and converted what was a killer disease into a chronic one.’’ Also speaking at the event,ex- Vice President of Uganda, Speciosa Wandira, who disclosed that 3.4 per cent of Nigerians were infected with the virus, said: “The challenges on us is the well being of the people of Africa, the people of Nigeria, the people of that state where you are governor. “As champions, we say focus, look at the data and focus, there is money in every ministry which is talking about the health of the people. When we talk about those who are infected, the bigger majority of Nigerians are free: 100 per cent minus 3.4 per cent: the bigger majority is not infected. ‘’So what do you do to protect this bigger majority? You must look at the social standards that inform HIV/AIDS. It is the poorest that are affected, it is the jobless that are affected; we advice that you focus on the women and the girls. ‘’What are those social issues that would put those girls more at risk and you put money in those areas: it could be education, it can be industry. What are those industries that are driving the economy, that will keep girls working and make them independent. ‘’That will take them away from feeling that they must have sex with somebody for them to have HIV/AIDS.” Former President Olusegun Obasanjo, a member of the group, who was to lead the former Presidents on the visit to senate President Bukola Saraki was, however, absent. Responding, Senate President, Bukola Saraki, said the National Assembly would continue to give required attention to the fight against HIV/AIDS in the country. He stressed that the leadership of the National Assembly was not only concerned about the spread of HIV/AIDS in Nigeria in particular and and Africa in general, but also would continue to assist in efforts, including appropriating adequate funds, to agencies in the country devoted to tackling the pandemic. Saraki said: “We all know the importance of the fight against HIV/AIDS. You made a point that it seems we are beginning to relax concerning the danger posed by the disease. The initiative you have taken to raise more awareness is commendable. ‘’We in the National Assembly will continue to champion advocacy and creation of awareness concerning the scourge including making necessary budgetary allocation to aid the fight. “We did it in the case of Polio. When I was the Governor of Kwara State, we, the governors across the country saw that there was no coordination between the Federal Government and the State governments on the efforts being made to eradicate Polio. ‘’We organized a seminar where we sat with the Bill Gates Foundation, to chart a new way forward. This resulted in the resounding success we witness currently.’’
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Gay and bisexual men across England to benefit from HPV jab scheme 

Gay and bisexual men across England to benefit from HPV jab scheme  | Virology News | Scoop.it
Gay and bisexual men across England will be offered the HPV jab following a successful pilot carried out at two sexual health clinics in Brent.
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The remarkable Scottish professor who discovered the Zika virus

The remarkable Scottish professor who discovered the Zika virus | Virology News | Scoop.it
Read The remarkable Scottish professor who discovered the Zika virus latest on ITV News. All the Science, Health news
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Love the history of virology B-)
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Could treatment of hepatitis C virus infections help prevent virus transmission?

Could treatment of hepatitis C virus infections help prevent virus transmission? | Virology News | Scoop.it
An international team of researchers has shed light on the potential impact of new drugs for hepatitis C virus (HCV).
HCV is an important cause of liver cancer and is transmitted through blood to blood contact. People who inject drugs (PWID) and men who have sex with men (MSM), who are also infected with HIV, are key risk groups for HCV infection in UK.
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Luminous proteins offer new method to discover viral infections

Researchers have developed a new method to directly follow viral infections in living organisms. This method can make infected cells produce fluorescent proteins, which means that they light up and become easier to identify. The method also makes it possible to activate other functions in infected cells, for instance to enhance the immune system.
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The ‘beating heart’ of the flu virus – and why scientists want to commandeer it

The ‘beating heart’ of the flu virus – and why scientists want to commandeer it | Virology News | Scoop.it
Understanding how the flu virus copies itself could open a way to killing it.
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Infographic: Progress Toward an HIV Vaccine

Infographic: Progress Toward an HIV Vaccine | Virology News | Scoop.it
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REACTing: the French response to infectious disease crises

In the past decade, scientific and health systems have been challenged by an increase in the emergence of infectious diseases such as Middle East respiratory syndrome coronavirus, chikungunya, Ebola virus disease, and Zika virus.1, 2, 3, 4 An effective and global public health response to these crises depends on our ability to anticipate these events and our level of preparedness. However, the development of research programmes in response to a rapidly emerging infectious disease in an emergency context is a challenge. Any delay in the response can result in serious consequences for the evolution of the crisis.5
In France, after the 2009 pandemic of influenza A H1N1, many obstacles were identified when organising the research response.6 These issues included delays in political commitment and the mobilisation of the researchers; little coordination of the different stakeholders; problems with raising funds; administrative, regulatory, and ethical difficulties; and insufficient national and international collaboration.

Lessons learnt from this pandemic led different French research organisations involved in biomedical research to propose REACTing (REsearch and ACTion targeting emerging infectious diseases), a new concept for scientific coordination and fundraising to improve research preparedness during peacetime and to optimise research capacity for a prompt response during a crisis.
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Liberté, égalité, fraternité…santé - The Lancet

“We are not England, we are not France”, said Hillary Clinton about health-care insurance during a recent US presidential debate. European models of health care have their own history in which redistribution forms the cornerstone of social solidarity. Aiming to guarantee social cohesion, France's Etat Providence is rooted in models of a welfare state that developed in Germany and the UK. Ensuring universal health coverage and financed through payroll taxes, and increasingly through a general social contribution on all types of income, French health insurance is characterised by a strong redistributive scheme that benefits the poorest and the most sick.1 Private and public health-care providers coexist in France and patients have the choice to be treated wherever they wish. Patients are reimbursed by the compulsory national insurance with any uncovered costs covered by private companies, half of which are non-profit insurers. This model is widely considered efficient. France was ranked first in WHO's World Health Report on health systems in 2000, although the report also highlighted health inequalities across the country.2
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Cell substrates for the production of viral vaccines

Vaccines have been used for centuries to protect people and animals against infectious diseases. For vaccine production, it has become evident that cell culture technology can be considered as a key milestone and has been the result of decades of progress. The development and implementation of cell substrates have permitted massive and safe production of viral vaccines. The demand in new vaccines against emerging viral diseases, the increasing vaccine production volumes, and the stringent safety rules for manufacturing have made cell substrates mandatory viral vaccine producer factories. In this review, we focus on cell substrates for the production of vaccines against human viral diseases. Depending on the nature of the vaccine, choice of the cell substrate is critical. Each manufacturer intending to develop a new vaccine candidate should assess several cell substrates during the early development phase in order to select the most convenient for the application. First, as vaccine safety is quite naturally a central concern of Regulatory Agencies, the cell substrate has to answer the regulatory rules stringency. In addition, the cell substrate has to be competitive in terms of viral-specific production yields and manufacturing costs. No cell substrate, even the so-called “designer” cell lines, is able to fulfil all the requested criteria for all viral vaccines. Therefore, the availability of a variety of cell substrates for vaccine production is essential because it improves the chance to successfully respond to the current and future needs of vaccines linked to new emerging or re-emerging infectious diseases (e.g. pandemic flu, Ebola, and Chikungunya outbreaks).
Ed Rybicki's insight:
Interesting though this is from a vaccinology point of view, they don't mention plants or plant cells once. Fail!!
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No, this isn’t the start of the antibiotic apocalypse, just bad reporting

No, this isn’t the start of the antibiotic apocalypse, just bad reporting | Virology News | Scoop.it
New drug-resistant infection is cause for measured concern, but let’s get the facts straight.
Ed Rybicki's insight:
Love it: debunking the apocalyptic hype!
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Bivalent Vaccine Takes SE Asia ‘Critical’ Step Closer To Ending Polio

Bivalent Vaccine Takes SE Asia ‘Critical’ Step Closer To Ending Polio https://t.co/I2fddR1qnb
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Cameroon hit by a bird flu outbreak in a major poultry facility

A bird flu outbreak has killed 15000 fowls at a neighbourhood in Yaounde, capital of Cameroon. The deaths, linked to the Avian Influenza, were confirmed by ...
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Living with HIV and the struggle to survive Malawi drought 

Malawi: Using mobile phones to help the vulnerable survive the drought
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New Approaches to Vaccines for Human and Veterinary Tropical Diseases. Or maybe sophisticated safari science?

The Keystone Symposia organisation held a meeting entitled "New Approaches to Vaccines for Human and Veterinary Tropical Diseases" in Cape Town this week (May 22-26, 2016).  A summary of the meeting was given as: "Human and livestock vaccines can contribute to improved human welfare and income generation by maintaining human health and meeting the demand…
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How Viruses infect Bacteria: A Tale of a Tail

How Viruses infect Bacteria: A Tale of a Tail | Virology News | Scoop.it
Bacteriophages are viruses that infect bacteria. Using state-of-the-art tools, EPFL scientists have described a million-atom "tail" that bacteriophages use to breach bacterial surfaces. The breakthrough has major implications for science and medicine, as bacteriophages are widely used in research. To infect bacteria, most bacteriophages employ a 'tail' that stabs and pierces the bacterium's membrane to…
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Ice Caps Melt, Prehistoric Virus Escapes. No, It's Not a Movie.

Ice Caps Melt, Prehistoric Virus Escapes. No, It's Not a Movie. | Virology News | Scoop.it
Two specimens of pandoraviruses have been found in shallow water sediments, one in Chile and the other one in Australia. They were both so big that they could be seen with just an optical microscope, reaching 1 μm in length and 0.5 μm in diameter. The researchers found over 2,000 genes in these pandoraviruses, of which over 90% looked nothing like any other previously known gene. In fact, they appear to be unrelated to the previously discovered megaviruses. So what are they? A fourth domain of life? A completely isolated niche in the tree of life? Or could they be — as the sci-fi writer in me wants to think — the remnants of a completely different form of life, one that existed so long ago that these gigantic particles are all there is left of it?
Ed Rybicki's insight:
Ho, hum: been there, debunked that....
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Polio Virus Treatment Success in Brain Cancer Trial Brings Hope to All Cancer Patients

Polio Virus Treatment Success in Brain Cancer Trial Brings Hope to All Cancer Patients | Virology News | Scoop.it
The U.S. Food and Drug Administration granted breakthrough therapy designation this month to a polio virus for the treatment of recurrent glioblastoma brain cancer. The designation came after nearly unprecedented results during a Phase I clinical trial from Duke University
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