HPV Vaccine: The Earlier, the Better. HPV Vaccine: The Earlier, the Better
Women who were 18 and up or had abnormal cervical cytology when vaccinated against human papillomavirus (HPV) subsequently had rates ofCervical dysplasiasimilar to those of unvaccinated women, Canadian investigators reported.
Women ≥18 without cervical abnormalities at vaccination had a 23% reduction in the risk of high-grade squamous intraepithelial lesions (HSIL) as compared with unvaccinated women. The quadrivalent vaccine did not appear to protect against HSIL among women who had abnormal cytology at the time they were vaccinated, they reported online in the Journal of Clinical Oncology.
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