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Mexico slaughters 1.2 million chickens infected with bird flu

Mexico slaughters 1.2 million chickens infected with bird flu | Virology News | Scoop.it
Mexico slaughters 1.2 million chickens infected with bird flu
CNN International
(CNN) -- Mexican authorities say they've slaughtered more than a million chickens infected with bird flu.
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Here we go - again.

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like zombies B-)
Curated by Ed Rybicki
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Clinical development of gene therapy: results and lessons from recent successes

Clinical development of gene therapy: results and lessons from recent successes | Virology News | Scoop.it
Therapeutic gene transfer holds the promise of providing lasting therapies and even cures for diseases that were previously untreatable or for which only temporary or suboptimal treatments were available. For some time, clinical gene therapy was characterized by some impressive but rare examples of successes and also several setbacks. However, effective and long-lasting treatments are now being reported from gene therapy trials at an increasing pace. Positive outcomes have been documented for a wide range of genetic diseases (including hematological, immunological, ocular, and neurodegenerative and metabolic disorders) and several types of cancer. Examples include restoration of vision in blind patients, eradication of blood cancers for which all other treatments had failed, correction of hemoglobinopathies and coagulation factor deficiencies, and restoration of the immune system in children born with primary immune deficiency. To date, about 2,000 clinical trials for various diseases have occurred or are in progress, and many more are in the pipeline. Multiple clinical studies reported successful treatments of pediatric patients. Design of gene therapy vectors and their clinical development are advancing rapidly. This article reviews some of the major successes in clinical gene therapy of recent years.

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HIV: New, powerful technique finds dormant virus hiding in rare cells

HIV: New, powerful technique finds dormant virus hiding in rare cells | Virology News | Scoop.it
Scientists have discovered a highly accurate way to find and reactivate dormant HIV hiding in rare cells in patients on antiretroviral therapy.
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Are ongoing concerns about vaccine safety to blame for the measles epidemic?

Are ongoing concerns about vaccine safety to blame for the measles epidemic? | Virology News | Scoop.it
In 2000, measles was declared eliminated in the US. But last year saw a record number of measles cases since - 644 over 27 US states. This year is unlikely to be any better, with 102 cases reported so far.
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Health-E News: Fighting the Superbugs

Health-E News: Fighting the Superbugs | Virology News | Scoop.it
Pneumonia, gonorrhoea and urinary tract infections that no longer respond to antibiotics are fast becoming a reality worldwide. Last week, global leaders pledged to unite to protect the medicines that protect us.
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Smallest-reported artificial virus could help advance gene therapy

Gene therapy is a kind of experimental treatment that is designed to fix faulty genetic material and help a patient fight off or recover from a disease. Now scientists have engineered the smallest-reported virus-like shell that can self-assemble. It could someday carry potentially therapeutic DNA or RNA and transfer it to human cells.
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Two more die in Crimean-Congo virus flare-up  

Two more die in Crimean-Congo virus flare-up    | Virology News | Scoop.it
LAHORE: Two more Congo patients died in Lahore and Peshawar on Saturday as the deadly virus cases intensified and remained uncontrolled across the country.
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Chikungunya virus not likely to infect twice

Here’s good news for anyone affected by chikungunya this year: the virus is unlikely to infect them ever again. This has been confirmed to TOI by virologists from AIIMS who said that the chikungunya virus has only one serotype and hence the risk of repeated infection is minimal.
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Zoo elephant tests positive for herpes virus

Zoo elephant tests positive for herpes virus | Virology News | Scoop.it
An Asian elephant at the Oklahoma City Zoo has tested positive for the EEHV1A virus for the second time in five months, a zoo official aid Friday. Low levels of the virus were detected in Achara's blood in a round of testing done this week. Each of the zoo's five elephants is tested weekl
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Brazil to begin Zika vaccine trials in humans

Spread the newsBrazil to begin Zika vaccine trials in humans RIO DE JANEIRO – Brazil will begin testing a vaccine
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Fears deadly ‘new Ebola’ virus heading to BRITAIN on tick invasion. Not.

Fears deadly ‘new Ebola’ virus heading to BRITAIN on tick invasion. Not. | Virology News | Scoop.it
“The risk to the wider population is negligible as the tick that carries CCHF is not established in the UK and it cannot survive here.”
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“The risk to the wider population is negligible as the tick that carries CCHF is not established in the UK and it cannot survive here.” And it is endemic where I live, and I've never met anyone who is even seropositive?
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Background to Ebola's 40th: The Discovery of Filoviruses

Background to Ebola's 40th: The Discovery of Filoviruses | Virology News | Scoop.it
Ebola is 40 today! The discovery of filoviruses: Marburg and Ebola Marburg virus In 1967, the world was introduced to a new virus: thirty-one people in Marburg and Frankfurt in Germany, and Belgrade in the then Yugoslavia, became infected in a linked outbreak with a novel haemorrhagic fever agent. Twenty-five of them were laboratory workers associated…
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The global burden of viral hepatitis from 1990 to 2013

The global burden of viral hepatitis from 1990 to 2013 | Virology News | Scoop.it
Viral hepatitis is a leading cause of death and disability worldwide. Unlike most communicable diseases, the absolute burden and relative rank of viral hepatitis increased between 1990 and 2013. The enormous health loss attributable to viral hepatitis, and the availability of effective vaccines and treatments, suggests an important opportunity to improve public health.

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Towards next generation maggot debridement therapy: transgenic Lucilia sericata larvae that produce and secrete a human growth factor

Towards next generation maggot debridement therapy: transgenic Lucilia sericata larvae that produce and secrete a human growth factor | Virology News | Scoop.it
Diabetes and its concurrent complications impact a significant proportion of the population of the US and create a large financial burden on the American health care system. FDA-approved maggot debridement therapy (MDT), the application of sterile laboratory-reared Lucilia sericata (green bottle fly) larvae to wounds, is a cost-effective and successful treatment for diabetic foot ulcers and other medical conditions. Human platelet derived growth factor-BB (PDGF-BB) is a secreted dimeric peptide growth factor that binds the PDGF receptor. PDGF-BB stimulates cell proliferation and survival, promotes wound healing, and has been investigated as a possible topical treatment for non-healing wounds. Genetic engineering has allowed for expression and secretion of human growth factors and other proteins in transgenic insects. Here, we present a novel concept in MDT technology that combines the established benefits of MDT with the power of genetic engineering to promote healing. The focus of this study is to create and characterize strains of transgenic L. sericata that express and secrete PDGF-BB at detectable levels in adult hemolymph, whole larval lysate, and maggot excretions/ secretions (ES), with potential for clinical utility in wound healing. We have engineered and confirmed transgene insertion in several strains of L. sericata that express human PDGF-BB. Using a heat-inducible promoter to control the pdgf-b gene, pdgf-b mRNA was detected via semi-quantitative PCR upon heat shock. PDGF-BB protein was also detectable in larval lysates and adult hemolymph but not larval ES. An alternative, tetracycline-repressible pdgf-b system mediated expression of pdgf-b mRNA when maggots were raised on diet that lacked tetracycline. Further, PDGF-BB protein was readily detected in whole larval lysate as well as larval ES. Here we show robust, inducible expression and production of human PDGF-BB protein from two conditional expression systems in transgenic L. sericata larvae. The tetracycline-repressible system appears to be the most promising as PDGF-BB protein was detectable in larval ES following induction. Our system could potentially be used to deliver a variety of growth factors and anti-microbial peptides to the wound environment with the aim of enhancing wound healing, thereby improving patient outcome in a cost-effective manner.
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Now THAT'S cool! Using a VERY old technique, modernised with maggots that make a HGF!
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Vaccine messages: keep it simple

Vaccine messages: keep it simple | Virology News | Scoop.it
A new study has found that people find simple, fact-based vaccination messages most convincing. | Vaccines Today
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Amen.
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CDC Study: Flu Vaccine Saved 40,000 Lives During 9 Year Period 

CDC Study: Flu Vaccine Saved 40,000 Lives During 9 Year Period - CDC
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Antibiotic-resistant superbugs are the biggest global health threat, UN says

The world is taking unprecedented steps to address the rise in antibiotic resistant infections during a summit at the United Nations General Assembly on Tuesday.
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THEN viruses.
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In Uganda, Fort Detrick Researchers Seek Key to Ebola Virus

In Uganda, Fort Detrick Researchers Seek Key to Ebola Virus | Virology News | Scoop.it
Army researchers from Fort Detrick are developing relationships with Ebola survivors in Uganda.
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Anthrax? Ebola? No, the REAL killer is...flu!

Anthrax? Ebola? No, the REAL killer is...flu! | Virology News | Scoop.it
Influenza kills between 250,000 and 500,000 people worldwide every year. The virus travels efficiently via large airborne droplets, when infected people sneeze, cough or talk.
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I thought 400K, but hey, I could be wrong...?
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Deer Orbivirus Spreading Throughout Illinois

Deer Orbivirus Spreading Throughout Illinois | Virology News | Scoop.it
Deer hunting season doesn't start for a couple more weeks, but a virus has already taken out dozens of deer.
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Epizootic hemorrhagic disease (EHD) - an orbivirus. We can vaccines against those...B-)
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DNA-Based Vaccine Guards Against Zika in Monkey Study

THURSDAY, Sept. 22, 2016 (HealthDay News) -- An experimental DNA-based vaccine protected monkeys from infection with the birth defects-causing Zika virus, and it has proceeded to human safety trials, researchers report.
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Rift Valley fever outbreak in Niger kills 21

Health workers in western Niger are racing to contain an outbreak of Rift Valley fever that has killed at least 21 people over the past month, an aid agency said on Wednesday [21 Sep 2016].

The highly contagious disease, which is transmitted to humans by mosquitoes or close contact with contaminated animals, has infected 52 people in Niger's western region of Tahoua since late August, the country's health ministry said.

The Alliance for International Medical Action (ALIMA) and Niger's health authorities have opened an emergency treatment center, in the region's hardest-hit district of Tchintabaraden, to look after the infected and stop the disease from spreading.

"Unfortunately, the 52 severe cases officially registered at present only represent the tip of the iceberg," ALIMA's medical coordinator Oumarou Maidadji said in a statement.

With no specific treatment or effective human vaccine, Rift Valley fever can cause blindness and severe haemorrhaging, leading the victim to vomit blood or even bleed to death.

Herders and farmers [and veterinarians] are deemed at higher risk of infection from the disease, which can devastate livestock.

Niger's health ministry said people in the Tahoua region, especially pastoralists, should avoid handling meat from infected animals, boil raw milk before consumption, and ensure that the corpses of dead animals are buried carefully.

ALIMA is also working with local partners and doctors to provide a mobile clinic which travels the region to inform the public about the disease and how to prevent it from spreading.
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A real, as opposed to the previous imaginary threat.
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Angola, Congo yellow fever outbreak under control : WHO

Angola, Congo yellow fever outbreak under control : WHO | Virology News | Scoop.it
A yellow fever outbreak in Angola and Congo has been brought under control by a major vaccination campaign, the World Health Organization’s director of infectious hazard management Sylvie Briand has said. “One (piece of) good news is that this outbreak is under control now. We haven’t had any new cases in Angola since June 23, …
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Is Another Zika Brewing in the Caribbean?

Is Another Zika Brewing in the Caribbean? | Virology News | Scoop.it
Researchers have identified an illness that is carried by mosquitoes and has never been seen in the Caribbean.
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Ebola discovered in Belgium 40 years ago

Ebola discovered in Belgium 40 years ago | Virology News | Scoop.it

The Antwerp Institute of Tropical Medicine (ITM) is staging a week-long international conference to mark the 40th anniversary of the discovery of the Ebola virus. | Daily {adj} news in English. 

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