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Twitter / anjantz: My virology professor is wearing ...

My virology professor is wearing a "Got herpes?" Shirt! Lol on Valentines Day! #coincidence? I think not! Lol http://t.co/1VUQtvD0
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Excellent...!  Right up there with "What's the difference between love and herpes?  Answer - herpes LASTS...!"

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like zombies B-)
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Avian influenza H9N2 virus isolated from air samples in LPMs in Jiangxi, China

Avian influenza H9N2 virus isolated from air samples in LPMs in Jiangxi, China | Virology News | Scoop.it
Recently, avian influenza virus has caused repeated worldwide outbreaks in humans. Live Poultry Markets (LPMs) play an important role in the circulation and reassortment of novel Avian Influenza Virus (AIVs). Aerosol transmission is one of the most important pathways for influenza virus to spread among poultry, from poultry to mammals, and among mammals. In this study, air samples were collected from LPMs in Nanchang city between April 2014 and March 2015 to investigate possible aerosol transmission of AIVs. Air samples were detected for Flu A by Real-Time Reverse Transcription-Polymerase Chain Reaction (RRT-PCR). If samples were positive for Flu A, they were inoculated into 9- to 10-day-old specific-pathogen-free embryonated eggs. If the result was positive, the whole genome of the virus was sequenced by MiSeq. Phylogenetic trees of all 8 segments were constructed using MEGA 6.05 software. To investigate the possible aerosol transmission of AIVs, 807 air samples were collected from LPMs in Nanchang city between April 2014 and March 2015. Based on RRT-PCR results, 275 samples (34.1%) were Flu A positive, and one virus was successfully isolated with embryonated eggs. The virus shared high nucleotide homology with H9N2 AIVs from South China. Our study provides further evidence that the air in LPMs can be contaminated by influenza viruses and their nucleic acids, and this should be considered when choosing and evaluating disinfection strategies in LPMs, such as regular air disinfection. Aerosolized viruses such as the H9N2 virus detected in this study can increase the risk of human infection when people are exposed in LPMs.
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New HIV Injection Could Replace Daily Pill

New HIV Injection Could Replace Daily Pill | Virology News | Scoop.it
A study has found HIV can effectively be controlled by a jab given every two months.
Scientists tested an injectable anti-retroviral therap
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Koalas Are Enduring a Pandemic Like Those Our Ancestors Faced

Koalas Are Enduring a Pandemic Like Those Our Ancestors Faced | Virology News | Scoop.it
To understand what it means to be human, you have to understand koalas. Or, to be more precise, you have to understand how they are dying from a bizar
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Centre for Pathogen Evolution

Welcome to the Centre for Pathogen Evolution The Centre for Pathogen Evolution is based within the Department of Zoology, at the University of Cambridge. The Pathogen Evolution Group is dedicated to research in antigenically variable pathogens and pathogen evolution, and to contribute to basic...
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An HIV Vaccine Inches Closer

An HIV Vaccine Inches Closer | Virology News | Scoop.it
HIV was (and still very much is) a critical issue for tens of millions of people around the world. The virus can spread quickly, particularly if care isn’t taken with medical…
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Dentists condemn failure on HPV vaccinations

Dentists condemn failure on HPV vaccinations | Virology News | Scoop.it
Dentists have condemned news that the Joint Committee on Vaccination and Immunisation (JCVI) has decided not to recommend an extension of the Human Papilloma Virus (HPV) vaccination to school age boys.
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High-dose influenza vaccine in nursing home residents: not to be sneezed at

High-dose influenza vaccine in nursing home residents: not to be sneezed at | Virology News | Scoop.it
In this issue of The Lancet Respiratory Medicine, Stefan Gravenstein and colleagues1 present data from a large cluster-randomised trial done to identify whether high-dose, inactivated influenza vaccine can provide better protection against severe inf
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Cow antibodies yield important clues for developing a broadly effective AIDS vaccine

Cow antibodies yield important clues for developing a broadly effective AIDS vaccine | Virology News | Scoop.it
Credit: IAVI LA JOLLA - Cows are leaving the pasture and entering the field...of HIV vaccine research. As outlined in a study published today in Nature, lead author Devin Sok, Director, Antibody Di..
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High-dose influenza vaccine leads to lower hospitalizations in nursing home residents

Electron microscopy of influenza virus. Credit: CDC In the largest nursing home study to date on the effect of a high dose (HD) flu vaccine, researchers found that vaccines with four times the antigen of standard flu (SD) vaccines significantly reduced the risk of respiratory and all-cause hospitalization during flu […]
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Only US company that makes yellow fever vaccine closes

Just one medical facility in New Hampshire has the vaccine in stock. Subscribe to WMUR on YouTube now for more: http://bit.ly/1lOjX9C Get more Mancheste
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Development of real-time and lateral flow dipstick recombinase polymerase amplification assays for rapid detection of goatpox virus and sheeppox virus

Development of real-time and lateral flow dipstick recombinase polymerase amplification assays for rapid detection of goatpox virus and sheeppox virus | Virology News | Scoop.it
Goatpox virus (GTPV) and sheeppox virus (SPPV), which belong to the Capripoxvirus (CaPV), are economically important pathogens of small ruminants. Therefore, a sensitive, specific and rapid diagnostic assay for detection of GTPV and SPPV is necessary to accurately and promptly control these diseases. Recombinase polymerase amplification (RPA) assays combined with a real-time fluorescent detection (real-time RPA assay) and lateral flow dipstick (RPA LFD assay) were developed targeting the CaPV G-protein-coupled chemokine receptor (GPCR) gene, respectively. The sensitivity of both CaPV real-time RPA assay and CaPV RPA LFD assay were 3 × 102 copies per reaction within 20 min at 38 °C. Both assays were highly specific for CaPV, with no cross-reactions with peste des petits ruminants virus, foot-and-mouth disease virus and Orf virus. The evaluation of the performance of these two assays with clinical sample (n = 107) showed that the CaPV real-time RPA assay and CaPV RPA LFD assay were able to specially detect SPPV or GTPV present in samples of ovine in liver, lung, kidney, spleen, skin and blood. This study provided a highly time-efficient and simple alternative for rapid detection of GTPV and SPPV.
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First vaccine to show protection against gonorrhoea

First vaccine to show protection against gonorrhoea | Virology News | Scoop.it
Exposure to the meningococcal group B vaccine during a New Zealand mass vaccination campaign was associated with a reduced likelihood of contracting gonorrhoea, compared with unvaccinated people, according to a new study of more than 14,000 people published in The Lancet. This is the first time that a vaccine has shown any protection against gonorrhoea, and may provide a new avenue for vaccine development.
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Given the rapid development of multiply-resistant strains, this is a really good development. 
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Researchers report advance in search for vaccine to fight CMV 

Researchers from Duke University School of Medicine and Tulane National Primate Research Center report findings in monkeys that demonstrates a vaccine approach for cytomegalovirus, or CMV, that appears to be capable of protecting the animal's fetus from infection.
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Smart vaccine refrigerator provides people with life-saving medicines worldwide

Smart vaccine refrigerator provides people with life-saving medicines worldwide, using KPN’s IoT connectivity
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Experts puzzled by SA bird flu

Experts puzzled by SA bird flu | Virology News | Scoop.it
Experts puzzled by SA bird flu Research is still being conducted to establish just how wild birds have infected thousands of chickens in South Africa with a highly pathogenic H5N8 strain
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South African girl, 9, becomes only the third child to be 'functionally cured' of HIV

South African girl, 9, becomes only the third child to be 'functionally cured' of HIV | Virology News | Scoop.it
The patient still has HIV in her system but it is so weakened that it cannot replicate or spread.
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Lyme disease vaccine on the way – if only the anti-vaxxers stay away

Lyme disease vaccine on the way – if only the anti-vaxxers stay away | Virology News | Scoop.it
Even though dogs have access to a Lyme disease vaccine, there have not been any available for humans for 18 years. But that's about to change.
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Donor Government Funding For HIV Declines By 7% In 2016, Lowest Level Since 2010

Ghana News Agency: Donor government funding to support HIV dips “Donor government funding to support HIV efforts in low- and middle-income countries decreased by US$511 million from US$7.5 billion in 2015 to US$7 billion in 2016, a new report has revealed. It was produced by the Kaiser Family Foundation and the Joint United Nations Programme…More
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HPV vaccine: Why aren’t children getting it? 

CBS News HPV vaccine: Why aren't children getting it? - CBS News CBS News The most underutilized immunization for children can also prevent many forms of cancer - but one-third of girls and one-half of boys aren't being vaccinated. and more » from #Cancer-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2eMyNSB via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos…
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Approximately 90% of adults are at risk for Shingles 

Approximately 90% of adults are at risk for Shingles  | Virology News | Scoop.it
Dr Glass says almost anyone who over the age of 50 is at risk of getting shingles
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And those of us of a certain age...should get vaccinated!!
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For 1st time, over half of people with HIV taking AIDS drugs

LONDON (AP) — For the first time in the global AIDS epidemic that has spanned four decades and killed 35 million people, more than half of all those infected with HIV are on drugs to treat the virus, the United Nations said in a report released Thursday. (via: trendolizer.com)
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Drug combo could repair fetal alcohol damage

Drug combo could repair fetal alcohol damage | Virology News | Scoop.it
"We have identified a potential treatment for alcohol spectrum disorder. Currently, there is none."
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HUUUUGE news for South Africa: we have the world's highest incidence of this problem.
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New, More Effective Flu Vaccine Delivered Using Dissolvable Microneedle Patch

New, More Effective Flu Vaccine Delivered Using Dissolvable Microneedle Patch | Virology News | Scoop.it
Researchers at Georgia State University have developed a more effective way of delivering influenza vaccines thanks to a dissolvable microneedle array and
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The effects of potato virus Y-derived virus small interfering RNAs of three biologically distinct strains on potato ( Solanum tuberosum) transcriptome

The effects of potato virus Y-derived virus small interfering RNAs of three biologically distinct strains on potato ( Solanum tuberosum) transcriptome | Virology News | Scoop.it

Potato virus Y (PVY) is one of the most economically important pathogen of potato that is present as biologically distinct strains. The virus-derived small interfering RNAs (vsiRNAs) from potato cv. Russet Burbank individually infected with PVY-N, PVY-NTN and PVY-O strains were recently characterized. Plant defense RNA-silencing mechanisms deployed against viruses produce vsiRNAs to degrade homologous viral transcripts. Based on sequence complementarity, the vsiRNAs can potentially degrade host RNA transcripts raising the prospect of vsiRNAs as pathogenicity determinants in virus-host interactions. This study investigated the global effects of PVY vsiRNAs on the host potato transcriptome. The strain-specific vsiRNAs of PVY, expressed in high copy number, were analyzed in silico for their proclivity to target potato coding and non-coding RNAs using psRobot and psRNATarget algorithms. Functional annotation of target coding transcripts was carried out to predict physiological effects of the vsiRNAs on the potato cv. Russet Burbank. The downregulation of selected target coding transcripts was further validated using qRT-PCR. The vsiRNAs derived from biologically distinct strains of PVY displayed diversity in terms of absolute number, copy number and hotspots for siRNAs on their respective genomes. The vsiRNAs populations were derived with a high frequency from 6 K1, P1 and Hc-Pro for PVY-N, P1, Hc-Pro and P3 for PVY-NTN, and P1, 3′ UTR and NIa for PVY-O genomic regions. The number of vsiRNAs that displayed interaction with potato coding transcripts and number of putative coding target transcripts were comparable between PVY-N and PVY-O, and were relatively higher for PVY-NTN. The most abundant target non-coding RNA transcripts for the strain specific PVY-derived vsiRNAs were found to be MIR821, 28S rRNA,18S rRNA, snoR71, tRNA-Met and U5. Functional annotation and qRT-PCR validation suggested that the vsiRNAs target genes involved in plant hormone signaling, genetic information processing, plant-pathogen interactions, plant defense and stress response processes in potato. The findings suggested that the PVY-derived vsiRNAs could act as a pathogenicity determinant and as a counter-defense strategy to host RNA silencing in PVY-potato interactions. The broad range of host genes targeted by PVY vsiRNAs in infected potato suggests a diverse role for vsiRNAs that includes suppression of host stress responses and developmental processes. The interactome scenario is the first report on the interaction between one of the most important Potyvirus genome-derived siRNAs and the potato transcripts.
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Always a pleasure to share good work from old friends B-)
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Multivalent footrot vaccine developed by May 2018 

Multivalent footrot vaccine developed by May 2018  | Virology News | Scoop.it
MEAT and Livestock Australia hoped to have a cross-reactive footrot vaccine to protect against all serotypes of the crippling sheep condition by May 2018, MLA managing director Richard Norton told breeders in Bendigo last night.
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For sheep, folks, for sheep...B-)
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