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WHO | Novel coronavirus infection – update

WHO | Novel coronavirus infection – update | Virology News | Scoop.it
The United Kingdom (UK) has informed WHO of another confirmed case of infection with the novel coronavirus (NCoV). The patient is a UK resident and a relative of the case announced on 11 February 2013.
Ed Rybicki's insight:

This looks like person-to-person transmission; they also say the new case is a person who has "pre-existing medical conditions that may have increased susceptibility to respiratory infections".  So: like SARS, a nasty disease that can be transmitted between humans.  Let's hope it goes no further!  Thanks @cupton1!

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like zombies B-)
Curated by Ed Rybicki
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Nigeria: Lassa fever outbreak could kill 1,000 people as virus spreads to 17 states

Nigeria: Lassa fever outbreak could kill 1,000 people as virus spreads to 17 states | Virology News | Scoop.it
At least 63 people reported dead out of 212 cases recorded since virus outbreak started in August 2015.
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Yoruba genetically immune to Lassa fever virus?

Yoruba genetically immune to Lassa fever virus? | Virology News | Scoop.it
A university lecturer, Prof. Christian Happi, has claimed that Yoruba people, by the make-up of their genes, are immune to Lassa virus that causes Lassa fev
Ed Rybicki's insight:

I'm getting sick of Zika....

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African leaders advocate locally developed Zika, Lassa virus vaccines

African leaders, including ministers of health, finance, and other line ministries from Nigeria and at least 50 other African countries are meeting in Addis Ababa, Ethiopia, to discuss the potential of developing, manufacturing and implementing effective Zika virus and Lassa virus vaccines on the continent.
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Why Africa can't afford to have an outbreak of the Zika virus

Why Africa can't afford to have an outbreak of the Zika virus | Virology News | Scoop.it
With limited laboratory capacity and a lack of experts and funding, an outbreak of the Zika virus in Africa could be problematic.
Ed Rybicki's insight:

Yeah...sure.  It could be Bad.

 

BUT: as South African epidemiologists have pointed out, it'll only be a problem IF the mosquito that transmits it elsewhere, comes here - because our local A aegypti doesn't have the same behaviour, and will vastly outnumber and possibly outcompete any import variety.

 

And it's endemic in tropical Africa - meaning many people are immune already.

 

So scaremongering about Zika in Africa is possibly a little irresponsible - unless it's being used as a stalking horse for an agenda for setting up continent-wide arbovirus surveillance, or spurring on efforts to set up an African CDC.  Which I would heartily endorse.

 

The stuff about lack of reagents is spot-on: which is why we have a proposal in the works to provide just such, using plants to it.  Watch this space....

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Human evolution is more a muddy delta than a branching tree

Until recently, anthropologists drew the human family tree in the same way that my 10-year-old son solves a maze. He finds it much easier to work from the end to the beginning, because blind alleys lead with depressing sameness away from the start...
Ed Rybicki's insight:

We all of us, brothers and sisters...even you Denisovans!

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Mobile DNA Sequencing in the Ebola Epidemic

Mobile DNA Sequencing in the Ebola Epidemic | Virology News | Scoop.it

February 3, 2016 | Just over a year ago, Bio-IT World spoke to microbiologist Nick Loman about the recently released MinION DNA sequencer. The three-inch-long device, made by Oxford Nanopore Technologies of the UK, can read DNA in real time on a laptop, and Loman’s lab at the University of Birmingham was one of the first to receive one. Like many other early adopters we spoke to at the time, Loman was itching to try the MinION in real-world clinical contexts, following the genetic traces of an infection as it develops.

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Computer-designed protein protects against flu in mice

Computer-designed protein protects against flu in mice | Virology News | Scoop.it
A small protein molecule, engineered through computer design, protects against diverse strains of influenza in mice. Its preventive and therapeutic power does not depend on the animals’ own immune response to viral infection. 
These findings, from a multi-institutional study led by UW Medicine researchers in Seattle, are reported Feb. 4 in PLOS Pathogens. 
The researchers are trying to address the public health need for better methods to keep flu at bay. Vaccinations can deter flu infections, but they are strain-specific. Flu viruses are notorious for forming new genetic subtypes that can evade vaccines and acquire resistance to antiviral medications.
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Zika virus: Q&A with Sanofi executive developing a vaccine

Zika virus: Q&A with Sanofi executive developing a vaccine | Virology News | Scoop.it
Nicholas Jackson talks about Sanofi-Pasteur's efforts at developing a live vaccine against Zika virus. 
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The Lancet Zika virus resource centre

The Lancet Zika virus resource centre | Virology News | Scoop.it
The Lancet Zika virus resource centre brings together the best evidence from across The Lancet family of journals—offered with free access—to assist researchers, policy makers, and health workers, in understanding the effects of the outbreak and how best to respond. Find out more about Zika virus in thisSpecial Report.
 
 
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I'm not LMAO at ridiculous emails from my students

I'm not LMAO at ridiculous emails from my students | Virology News | Scoop.it
Convoluted excuses and drunken declarations of love can be amusing, but I’m genuinely concerned about young people’s communication skills
Ed Rybicki's insight:

Srsly! B-{

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Plush pandemic: a kinder, gentler pathogen

Colossal microbes taking over the world sounds like a B-movie plot, rather than the business plan of a stuffed toy manufacturer. We asked Drew Oliver, the creator and CEO of Giant Microbes, about how the company came about, how their products have been received and his plans for the future.
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Scientists' path to usable Zika vaccine strewn with hurdles

Scientists' path to usable Zika vaccine strewn with hurdles | Virology News | Scoop.it
The world is once again asking scientists and drugmakers to come up rapidly with a vaccine for a viral disease that, in the latest case, few people had heard of until a few weeks ago, and even fewer feared.
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This Indian biotech firm is the world’s first to ready a Zika vaccine for testing

This Indian biotech firm is the world’s first to ready a Zika vaccine for testing | Virology News | Scoop.it
Krishna Ella never expected to be holding the key to fighting a new global health emergency. Yet, his Indian firm—Bharat Biotech—has become the first to ready two vaccine candidates against the rapidly spreading Zika virus, which has already infected millions of people in Latin America. Zika doesn't cause much harm to adults. Most of the infected individuals...
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Nigeria battling fresh outbreak of the deadly Lassa fever

Nigeria battling fresh outbreak of the deadly Lassa fever | Virology News | Scoop.it
Nigeria is facing a growing outbreak of a deadly virus similar to Ebola which has already killed 101 people since August.
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Nigeria Contained Ebola; Can We Contain Lassa Fever and Zika Virus?

Nigeria Contained Ebola; Can We Contain Lassa Fever and Zika Virus? | Virology News | Scoop.it
On the 14th January 2016, the World Health Organisation declared an end of the Ebola outbreak in West Africa. Less than a day later, a new case in Sierra Leone was detected, indicating that the pat...
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Premium Scientific Pictures for ZIKA Virus

Premium Scientific Pictures for ZIKA Virus | Virology News | Scoop.it
Gallery: ZIKA Virus on Russell Kightley Premium Scientific Pictures
Ed Rybicki's insight:

I have no stake in this site B-)

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Buried Alive: Microbes from Ancient Halite

Buried Alive: Microbes from Ancient Halite | Virology News | Scoop.it
Halite is one of the most extreme environments to support life. From the drought of the Atacama Desert to salt deposits up to Permian in age and 2000 meters in burial depth, live microbes have been found. Because halite is geologically stable and impermeable to ground water, the microbes allegedly have a syndepositional origin, making them the oldest organisms known to live on Earth. Recently, our understanding of the microbial diversity inside halite has broadened, and the first genome sequences of ancient halite-buried microbes are now available. The secrets behind prolonged survival in salt are also starting to be revealed.
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Call for papers: The interplay between the host and HSV-1 infection

Call for papers: The interplay between the host and HSV-1 infection | Virology News | Scoop.it

Virology Journal is now inviting submissions for a new thematic series on “The interplay between the host and HSV-1 infection”. Edited by Chunfu Zheng (Soochow University, China), the collection welcomes research and review articles, and will also include specially commissioned topical reviews, written by leaders in the field.

Herpes simplex virus type 1 (HSV-1) is a typical human-restricted pathogen, which is carried by 50-90% of the population worldwide, with higher frequencies in developing countries. HSV-1 is well known for its ability to establish a lifelong latent infection in neurons and trigger reactivation and lytic infection, mainly in epithelial or mucosal cells.

Although HSV-1 was identified over 100 years ago, the battle between HSV-1 and the host continues, as there is no vaccine yet available, and HSV-1 is still one of the major infectious diseases worldwide.

We will consider articles covering the interplay between the host and HSV-1 infection, including but not limited to:

Virus-host interactionCellular responses to viral infectionPathogenesis and immunity

The aim for this thematic series is to help us not only improve our knowledge of virus-host interactions but also develop novel antiviral approaches and vaccines against HSV-1 infection.

The deadline for submissions is April 30th 2016. To submit your manuscript, please use our online submission system, and indicate in your cover letter that you would like the manuscript to be considered for this thematic series. If you would like to enquire about the suitability of a manuscript for consideration, please email a pre-submission enquiry tovirologyjournal@biomedcentral.com. 

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Pandemic Trailer Pulls You Into the Zombie Outbreak

Pandemic Trailer Pulls You Into the Zombie Outbreak | Virology News | Scoop.it
Watch the new Pandemic trailer. The zombie thriller stars Rachel Nichols, Mekhi Phifer, Pat Healy, Alfie Allen, and Missi Pyle.
Ed Rybicki's insight:

Because.  Zombies...B-)

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Production of Human papillomavirus pseudovirions in plants and their use in pseudovirion-based neutralisation assays in mammalian cells

Production of Human papillomavirus pseudovirions in plants and their use in pseudovirion-based neutralisation assays in mammalian cells | Virology News | Scoop.it
Human papillomaviruses (HPV) cause cervical cancer and have recently also been implicated in mouth, laryngeal and anogenital cancers.
Ed Rybicki's insight:

...and it has occurred to us that it can be a DNA vaccine vector too...B-)

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Concern over Zika virus grips the world - The Lancet

Concern over Zika virus grips the world - The Lancet | Virology News | Scoop.it

In the past week, the world has mobilised to tackle the latest threat to global health security—Zika virus, now spreading rapidly in the Americas. Udani Samarasekera and Marcia Triunfol report.

Worldwide concern over Zika virus (panel) and its temporal and geographical association with clusters of birth and neurological conditions escalated this week, with WHO declaring a Public Health Emergency of International Concern.

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Viral infection: A key host receptor for AAV

A transmembrane protein receptor that is critical for adeno-associated virus infection has been identified through an unbiased, genome-wide screen. Its role in viral entry could potentially be harnessed to develop enhanced gene therapy vectors and better animal models of human disease.
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Homeopathy: the air guitar of medicine

Homeopathy: the air guitar of medicine | Virology News | Scoop.it
Homeopathy is an alternative medicine, which means a few things. It means it’s not medicine, it’s an alternative; it means it’s seen by many as somehow better and healthier than modern medicines; and it means that people are incredibly emotional in their support for it. I’ve received death threats pretty much every time I’ve ever written …

Via Chris Upton + helpers
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