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Genetically modified tobacco plants produce antibodies to treat rabies

Genetically modified tobacco plants produce antibodies to treat rabies | Virology News | Scoop.it
Smoking tobacco is bad for your health, but a genetically altered version of the plant might provide an inexpensive cure for the deadly rabies virus.
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Going green...seriously, plants represent an extremely useful alternative production system for many biologicals - and especially for antibodies.  Some day, all monoclonals will be made this way...B-)

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Topical news snippets about viruses that affect people. And other things.
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Biopharming Regulations

Biopharmed drugs offer much promise; but how should they be regulated?

Using genetic engineering in plants to create biopharmed drugs holds all sorts of promise for treating diseases, as the recent case of a drug which appears to have cured two Ebola patients has shown, but regulators may be holding this field back, argues Henry Miller in a Wall Street Journal op-ed.

Biopharming involves genetically engineering crops such as corn, tomato, and tobacco to create high concentrations of antibodies and other pharmaceuticals that can then be harvested.

The drug used in the two US Ebola patients, called ZMapp, is one of these; a mixture of three antibodies taken from tobacco plants that were infected with engineered plant viruses. These kinds of drugs have such "great potential," Miller says, because the raw materials are cheap and they can be scaled up far more cheaply than bricks-and-mortar factories. That fluid scalability enables drug firms to hold off on investing in production facilities until later in the clinical testing cycle, or until the market it will target can be better estimated.

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Ebola outbreak: Congo becomes fifth country with confirmed cases

Ebola outbreak: Congo becomes fifth country with confirmed cases | Virology News | Scoop.it
Health minister says up to 15 people may have died but virus is not linked to epidemic that has spread through west Africa
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"One of the two cases that tested positive was for the Sudanese strain of the virus...while the other was a mixture of the Sudanese and the Zaire strain – the most dangerous. The virus in west Africa is the Zaire strain. "

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Fighting Ebola, and the Conspiracy Theories

Fighting Ebola, and the Conspiracy Theories | Virology News | Scoop.it
The developed world has the same problem with myths about vaccines. In Africa, working with trusted community leaders is a key.
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The Global Response to the Ebola Fever Epidemic: What Took So Long?

The Global Response to the Ebola Fever Epidemic: What Took So Long? | Virology News | Scoop.it

Mark J. Siedner of Harvard Medical School and John D. Kraemer of the O’Neill Institute for National and Global Health Law, Georgetown University, discuss the impact of the delayed global response to the Ebola epidemic.

On August 8, twenty weeks after the first suspected cases in what has become the worst hemorrhagic fever outbreak in history, the World Health Organization’s (WHO) Director-General declared the epidemic a public health emergency of international concern (PHEIC). The announcement, which signals that an epidemic constitutes a sufficient public health risk to member WHO States through the spread of disease, will ideally motivate financial and logistic support to the countries most affected. But after nearly 1,000 deaths, and for a disease where a relatively simple and coordinated public health response has extinguished prior epidemics, many are left wondering, “what took so long?”

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WHO: Number of People Infected By Ebola Virus Could be Much Greater

http://en.romereports.com Estimates on the number of people infected by the Ebola virus could be much greater than anticipated. According to the World Health Organization, staff members in...
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Ebola survivor 'thrilled to be alive'

Ebola survivor 'thrilled to be alive' | Virology News | Scoop.it
Ebola virus survivor Dr Kent Brantly has described how he is "thrilled to be alive" after contracting the infection while working in Liberia.
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Russian scientists to set up lab in Guinea to fight Ebola

Russian scientists to set up lab in Guinea to fight Ebola | Virology News | Scoop.it
A team of Russian virologists, epidemiologists and bacteriologists is leaving for Africa to organize laboratory diagnosis of the Ebola virus in Guinea, where the outbreak of the deadly fever is spreading fast.
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The Coming Great Deception: Will you take the Mark of the Beast?

The Coming Great Deception: Will you take the Mark of the Beast? | Virology News | Scoop.it
08/06/2014 – By: Jason Warfield (a.k.a. Mass Effect)  One thing I would like to start off with is how this Ebola scare has come to be and how it has all been planned, to peak in a very nasty and deceiving end game.  Propaganda to scare you into receiving injections to ease the purpose for ...More →
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I would say this is light relief, if it weren't so insidiously persuasive - and DETAILED.  Truly, these people have too much time on their hands!

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Ebola virus disease, a long terms perspective

David Heymann, professor of infectious disease epidemiology, and head and senior fellow, at the Chatham House Centre on Global Health Security was sent to investigate the first outbreaks of Ebola in 1 (RT @ChathamHouse: Podcast: David Heymann discusses...
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Ebola virus may not be contained in Nigeria as two more cases emerge

Ebola virus may not be contained in Nigeria as two more cases emerge | Virology News | Scoop.it
WorldStage Ebola virus may not be contained in Nigeria as two more cases emerge Al Jazeera America The two are spouses of a man and woman who had direct contact with Liberian-American Patrick Sawyer, who flew into Nigeria last month with the virus...
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Ebola virus outbreak: "This is why '75%' of victims are women"

Ebola virus outbreak: "This is why '75%' of victims are women" | Virology News | Scoop.it
The Independent Ebola virus outbreak: This is why '75%' of victims are women The Independent Maricel Seeger, a WHO spokeswoman in Monrovia, Liberia, said reaching women and educating them on the disease is crucial to tackling the virus' spread, as...
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No end in sight to Ebola outbreak, official says

No end in sight to Ebola outbreak, official says | Virology News | Scoop.it
There is no end in sight to the Ebola outbreak in West Africa, according to the head of the World Health Organization.
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"Scale up the supply of experimental Ebola drugs!"

"Scale up the supply of experimental Ebola drugs!" | Virology News | Scoop.it
Estimates of the probable impact of the outbreak show that existing stocks of potentially useful medicines are insufficient, says Oliver Brady.
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Tobacco-derived 'plantibodies' enter the fight against Ebola

Tobacco-derived 'plantibodies' enter the fight against Ebola | Virology News | Scoop.it
NEW YORK (Reuters) - Drugmakers' use of the tobacco plant as a fast and cheap way to produce novel biotechnology treatments is gaining global attention because of its role in an experimental Ebola therapy.The
Ed Rybicki's insight:

Nice account of ZMapp and some of the science behind it.

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Liberian Ministers Who Defied Ebola Order Fired

Liberian Ministers Who Defied Ebola Order Fired | Virology News | Scoop.it
Liberia's president has fired all Cabinet ministers and other top officials who defied her order to return to the country as it struggles with an unprecedented Ebola outbreak. A statement from Ellen Johnson Sirleaf's office late Monday did not say how many officials or which ones had been...
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Science, not God, saved him from Ebola

Science, not God, saved him from Ebola | Virology News | Scoop.it
Dr Kent Brantly thinks he survived the deadly Ebola virus thanks not to medicine and drugs but because of his Sky Daddy.
Ed Rybicki's insight:

Seriously: the medic who asked for the ZMapp because he felt himself getting sicker, now says "G-D did it"??

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DR Congo confirms Ebola outbreak

DR Congo confirms Ebola outbreak | Virology News | Scoop.it

The Democratic Republic of Congo has confirmed that an outbreak of haemorrhagic fever in the north of the country has been identified as Ebola.

Health Minister Felix Numbi told the BBC that tests on two people had confirmed the disease in Equateur province, where 13 had already died.

But he said the deaths occurred in an isolated area and the disease seemed a different strain to West Africa's.

Dr Numbi said a quarantine zone was being set up to contain the disease.

The cases are the first reported outside West Africa since the outbreak there began.

 
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Interesting - if tragic!  The 7th outbreak in DRC since 1976.

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Controversial HIV Bill is Signed Into Law in Uganda

Controversial HIV Bill is Signed Into Law in Uganda | Virology News | Scoop.it
Uganda has been hailed as a success story in fighting HIV\/AIDS, with prevalence rates dropping from 18 percent in 1992 to 6.4 percent in 2005. But activists fear a new HIV Bill will lead to lead to people shunning testing and treatment.
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Ebola outbreak: Police in Liberia open fire on crowd trying to break virus quarantine

Ebola outbreak: Police in Liberia open fire on crowd trying to break virus quarantine | Virology News | Scoop.it
Police in the Liberian capital fired live rounds and tear gas on Wednesday to disperse a stone-throwing crowd trying to break an Ebola quarantine imposed on their neighbourhood, as the death toll from the epidemic in West Africa hit 1,350.
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‘Avian AIDS’ virus poses threat to endangered New Caledonian parrots

‘Avian AIDS’ virus poses threat to endangered New Caledonian parrots | Virology News | Scoop.it
NEW Caledonian rainbow lorikeets infected with avian circovirus could act as a disease source, threatening native and endangered New Caledonian parrot...
Ed Rybicki's insight:

It's Beak and feather disease virus, as it happens.  Nice report - and our paper on BFDV in wild and endangered Cape Parrots in South Africa will be coming out soon, and will be featured here.

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Polio double vaccine gives better protection, study finds

Polio double vaccine gives better protection, study finds | Virology News | Scoop.it
Oral vaccine followed by injection could help fight disease in conflict-torn areas, according to WHO (RT @bsubram: #Polio double vaccine provides better protection. Study conducted with children in India.
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Vault nanoparticles show promise for cancer treatment and possible HIV cure

Vault nanoparticles show promise for cancer treatment and possible HIV cure | Virology News | Scoop.it

A multidisciplinary team of scientists from UCLA and Stanford University has used a naturally occurring nanoparticle called a vault to create a novel drug delivery system that could lead to advances in the treatment of cancer and HIV.The research team was led by Dr. Leonard Rome, associate director of UCLA’s California NanoSystems Institute, and Dr. Jerome Zack, co-director of the UCLA AIDS Institute, both of whom are also members of UCLA’s Jonsson Comprehensive Cancer Center. Co-first authors on the study were Daniel Buehler, a UCLA postdoctoral researcher and Matthew Marsden, adjunct assistant professor in the department of medicine and a member of the AIDS Institute.Their findings could lead to cancer treatments that are more effective with smaller doses and to therapies that could potentially eradicate the HIV virus.The paper is the cover story of the Aug. 26 print edition of the journal ACS Nano ("Bioengineered Vaults: Self-Assembling Protein Shell–Lipophilic Core Nanoparticles for Drug Delivery"), and it was recently published online.

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Liberian slums barricaded as ebola sets new record

Liberian slums barricaded as ebola sets new record | Virology News | Scoop.it
Riot police and soldiers acting on their president's orders used scrap wood and barbed wire to seal off 50,000 people inside their Liberian slum Wednesday, trying to contain the Ebola outbreak that has killed 1,350 people and counting across West...
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Successful siRNA Marburg Virus Treatment Offers Hope for Ebola Patients

Successful siRNA Marburg Virus Treatment Offers Hope for Ebola Patients | Virology News | Scoop.it
An experimental therapy showed success in monkeys with Marburg virus, offering hope for new treatments for related Ebola virus.
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Seals, not Spaniards, first brought TB to Americas

Seals, not Spaniards, first brought TB to Americas | Virology News | Scoop.it
Seals and sea lions may have brought a form of tuberculosis to the Americas, centuries before the Spanish did so (Blame the Spanish for #measles #malaria #influenza #smallpox but blame the seals for #tuberculosis via @newscientist
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ANOTHER species to be careful of...!

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