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Studies demonstrate costs of HPV vaccinations in low income countries | Vaccine News Daily

Studies demonstrate costs of HPV vaccinations in low income countries | Vaccine News Daily | Virology News | Scoop.it

Two recently published studies highlighted the costs of delivering vaccinations for human papillomavirus to primary school girls in Tanzania.

The studies both found that the cost of delivering the HPV vaccine to adolescent girls might be significantly higher than delivering vaccines to infants when the delivery schedule matches the established infant immunization schedule, MedicalXpress reports.

The first study, conducted by the World Health Organization, the National Institute for Medical Research in Tanzania and the London School of Hygiene, tested class-based and age-based vaccination in three districts in Tanzania. The study found that class-based delivery was generally cheaper at an estimated $9.76 per fully immunized girl and $1.3 million overall, excluding vaccine costs.

The second study, conducted by Raymond Hutubessy from the WHO and his colleagues, used the new Cervical Cancer Prevention and Control Costing tool during a five year planning period. The study estimated that the vaccine could be delivered at $12.40 for each fully immunized girl.

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like zombies B-)
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A novel mechanism of antibody-mediated enhancement of flavivirus infection

A novel mechanism of antibody-mediated enhancement of flavivirus infection | Virology News | Scoop.it
Author summary Antibodies are an important component of antiviral host responses and their binding to the surface of virus particles usually leads to neutralization of viral infectivity. In some instances, however, antibodies at sub-neutralizing concentrations can enhance infection of certain cells, because they facilitate the uptake of infectious virus-antibody complexes through interactions with antibody-specific cellular receptors (Fcγ receptors). This mechanism is designated antibody-dependent enhancement of infection and implicated in the pathogenesis of dengue and possibly Zika virus infections, both mosquito-transmitted flaviviruses. Here we describe a novel mechanism of infection enhancement by antibodies that is independent of interactions with Fcγ receptors, using another important human-pathogenic flavivirus, tick-borne encephalitis virus. We demonstrate that binding of a specific antibody to the envelope protein E at the viral surface promotes the exposure of a structural element that interacts with the lipids of the cellular plasma membrane, thus increasing infection. Our study provides new insights into mechanisms that potentially modulate the antiviral effects of antibody populations present in post-infection sera.
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Indian Scientists Testing Dendritic Therapy Against Cervix Cancer

Indian Scientists Testing Dendritic Therapy Against Cervix Cancer | Virology News | Scoop.it
Immunotherapy is a new approach that exploits body’s inner capability to put up a fight against cancer. Under the approach, either immune system is given a boost or the T cells are “trained’’ to identify recalcitrant cancer cells and kill them.
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Human infection with avian influenza A(H7N9) virus – China

Human infection with avian influenza A(H7N9) virus – China | Virology News | Scoop.it
On 18, 25 August and 4 September 2017, the National Health and Family Planning Commission of China (NHFPC) notified WHO of four additional laboratory-confirmed cases of human infection with avian influenza A(H7N9) virus in China.Details of the case-p
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5 African countries approach control of their HIV epidemics

Data released today from the US President’s Emergency Plan for AIDS Relief (PEPFAR) show that the HIV epidemic is coming under control in Lesotho. These results add to prior PEPFAR-supported …
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HPV test beats pap smears for detecting cervical cancer, trial shows

HPV test beats pap smears for detecting cervical cancer, trial shows | Virology News | Scoop.it
HPV screening is more effective at detecting precancerous lesions than pap tests, backing a new national cervical cancer screening program.
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HIV Risk Associated With Community Level Educational Status

HIV Risk Associated With Community Level Educational Status | Virology News | Scoop.it
Link found between HIV risk and individual and community level educational status. The study were more opt to engage in transactional sex, the exchange of sex for drugs.
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There’s no vaccine yet for stupidity: anti-HPV vaccine campaigning in Ireland

There’s no vaccine yet for stupidity: anti-HPV vaccine campaigning in Ireland | Virology News | Scoop.it
The recent comments by Finian McGrath on the HPV vaccine made Dr Amy Morgan despair
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Melbourne girl, eight, dies as Australia's 'horror' flu season continues

Melbourne girl, eight, dies as Australia's 'horror' flu season continues | Virology News | Scoop.it
Victoria’s health minister urges people to get vaccinated as eastern seaboard sees slight decline in cases
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MIT creates microscopic cups to deliver vaccine doses to kids in one injection

MIT creates microscopic cups to deliver vaccine doses to kids in one injection | Virology News | Scoop.it
WASHINGTON, Sept. 18 (Xinhua) -- One single injection carrying several doses of vaccines has become true thanks to the research of the Massachusetts Institute of Technology (MIT). The MIT reported the technical breakthrough on its website of MIT news last week, telling the world their method of...
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Zika virus and Zika fever

Zika virus and Zika fever | Virology News | Scoop.it

An emerging mosquito-borne arbovirus named Zika virus (ZIKV), of the family Flaviviridae and genus Flavivirus, is becoming a global health threat. ZIKV infection was long neglected due to its sporadic nature and mild symptoms. However, recently, with its rapid spread from Asia to the Americas, affecting more than 30 countries, accumulating evidences have demonstrated a close association between infant microcephaly and Zika infection in pregnant women. Here, we reviewed the virological, epidemiological, and clinical essentials of ZIKV infection.

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Workers get paid for stopping bird flu spread in Pampanga

Workers get paid for stopping bird flu spread in Pampanga | Virology News | Scoop.it
Nameless and faceless, an army of 316 men came out en masse here on Wednesday to receive wages for spending days culling ailing chickens, ducks and quails to help control the avian flu outbreak.
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The generally unheard-from side of avian flu
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Potential Hepatitis Delta Virus Infection Treatment Gets Orphan Drug Designation

Potential Hepatitis Delta Virus Infection Treatment Gets Orphan Drug Designation | Virology News | Scoop.it
The FDA has granted orphan drug status to pegylated interferon lambda 1a (Lambda, Eiger Bio, Inc.) as a potential treatment for chronic hepatitis delta virus (HDV) infection.
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So: now we have vaccines to Hepatitis A and B, treatments for C and D...E, you're still lagging!
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Sanofi teams with researchers to develop trispecific antibodies for HIV

Sanofi teams with researchers to develop trispecific antibodies for HIV
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Exclusive: Africa to get state-of-art HIV drugs for $75 a year

Exclusive: Africa to get state-of-art HIV drugs for $75 a year | Virology News | Scoop.it
Makers of generic AIDS drugs will start churning out millions of pills for Africa containing a state-of-the-art medicine widely used in rich countries, after securing a multi-million dollar guarantee that caps prices at just $75 per patient a year.
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Leading Physician Organizations Call for Shingles Vaccine for People Over 50

Leading Physician Organizations Call for Shingles Vaccine for People Over 50 | Virology News | Scoop.it
SAN FRANCISCO, Sept. 18, 2017 /PRNewswire-USNewswire/ -- The American Academy of Ophthalmology and the American Dermatological Association recommend people age 50 and older get the shingles vaccine – 10 years younger than a previous recommendation. It is now estimated that one in three people will develop
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Damn, I really should get vaccinated...!
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Smokers with HIV far more likely to die of lung cancer

Smokers with HIV far more likely to die of lung cancer | Virology News | Scoop.it
MIAMI, United States (AFP) — People who are infected with human immunodeficiency virus an
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HPV vaccine can improve chances of conception in some women

HPV vaccine can improve chances of conception in some women | Virology News | Scoop.it
More than 40 percent of American teens are now getting vaccinated against human papillomavirus (HPV). But, despite HPV infection being associated with reduced semen quality and lower pregnancy rates, there is still public concern about whether the HPV vaccine itself could affect future fertility.
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Hep B vaccine should be given sooner: pediatricians group

Hep b vaccine should be given sooner: pediatricians group MONDAY, Aug. 28, 2017 HealthDay News The first dose of the hepatitis B vaccine should be given t
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Gavi CEO blames anti-vaccine mums for return of diseases

Mothers refusing to vaccinate children are helping to bring deadly diseases back to the West as hostility to science puts the developed world at risk
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Marijuana Exposure Associated With Improved Immunity in HIV Patients

Marijuana Exposure Associated With Improved Immunity in HIV Patients | NORML PETERSBURG, VA — Patients with HIV who test positive for pas
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Who knows? But it sounded good B-)
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Crack down on vaccine disinformation to prevent next Minnesota measles outbreak

Crack down on vaccine disinformation to prevent next Minnesota measles outbreak | Virology News | Scoop.it
Hearing needed this fall on the vaccine misinformation campaign that fueled measles outbreak.
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Bacteriophage therapy to combat bacterial infections in poultry

Infections in poultry are an economic and health problem in Europe and worldwide. The most common infections are associated with salmonellosis, colibacillosis, campylobacteriosis, and others. The prevalence of Campylobacter-positive poultry flocks in European countries varies from 18% to 90%. In the United States, the prevalence of infected flocks is nearly 90%. A similar percentage of infection has been noted for salmonellosis (about 75–90%) and E. coli (90–95%). The occurence of Clostridium perfringens is a major problem for the poultry industry, with some estimates suggesting colonization of as many as 95% of chickens, resulting in clinical or subclinical infections. In the US, annual economic losses due to Salmonella infections run from $1.188 billion to over $11.588 billion, based on an estimated 1.92 million cases. Similar costs are observed in the case of other types of infections. In 2005 economic losses in the the poultry industry due to mortalities reached 1,000,000 USD. Infections caused by these pathogens, often through poultry products, are also a serious public health issue. The progressive increase in the number of multi-drug resistant bacteria and the complete ban on the use of antibiotics in livestock feed in the EU, as well as the partial ban in the US, have led to the growth of research on the use of bacteriophages to combat bacterial infections in humans and animals. The high success rate and safety of phage therapy in comparison with antibiotics are partly due to their specificity for selected bacteria and the ability to infect only one species, serotype or strain. This mechanism does not cause the destruction of commensal bacterial flora. Phages are currently being used with success in humans and animals in targeted therapies for slow-healing infections. They have also found application in the US in eliminating pathogens from the surface of foods of animal and plant origin. At a time of growing antibiotic resistance in bacteria and the resulting restrictions on the use of antibiotics, bacteriophages can provide an alternative means of eliminating pathogens.
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Virus like particle-based vaccines against emerging infectious disease viruses

Virus like particle-based vaccines against emerging infectious disease viruses | Virology News | Scoop.it

Emerging infectious diseases are major threats to human health. Most severe viral disease outbreaks occur in developing regions where health conditions are poor. With increased international travel and business, the possibility of eventually transmitting infectious viruses between different countries is increasing. The most effective approach in preventing viral diseases is vaccination. However, vaccines are not currently available for numerous viral diseases. Virus-like particles (VLPs) are engineered vaccine candidates that have been studied for decades. VLPs are constructed by viral protein expression in various expression systems that promote the selfassembly of proteins into structures resembling virus particles. VLPs have antigenicity similar to that of the native virus, but are non-infectious as they lack key viral genetic material. VLP vaccines have attracted considerable research interest because they offer several advantages over traditional vaccines. Studies have shown that VLP vaccines can stimulate both humoral and cellular immune responses, which may offer effective antiviral protection. Here we review recent developments with VLP-based vaccines for several highly virulent emerging or re-emerging infectious diseases. The infectious agents discussed include RNA viruses from different virus families, such as the Arenaviridae, Bunyaviridae, Caliciviridae, Coronaviridae, Filoviridae, Flaviviridae, Orthomyxoviridae, Paramyxoviridae, and Togaviridae families.

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Waterlogged: Six Tales of the Aquatic Undead

Waterlogged: Six Tales of the Aquatic Undead | Virology News | Scoop.it
Waterlogged: Six Tales of the Aquatic Undead: Horror Story Six-Packs, vol. 3 - Kindle edition by C. L. Hernandez, Walt McFee. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Waterlogged: Six Tales of the Aquatic Undead: Horror Story Six-Packs, vol. 3.
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I did say we do zombies too...B-)
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