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Studies demonstrate costs of HPV vaccinations in low income countries | Vaccine News Daily

Studies demonstrate costs of HPV vaccinations in low income countries | Vaccine News Daily | Virology News | Scoop.it

Two recently published studies highlighted the costs of delivering vaccinations for human papillomavirus to primary school girls in Tanzania.

The studies both found that the cost of delivering the HPV vaccine to adolescent girls might be significantly higher than delivering vaccines to infants when the delivery schedule matches the established infant immunization schedule, MedicalXpress reports.

The first study, conducted by the World Health Organization, the National Institute for Medical Research in Tanzania and the London School of Hygiene, tested class-based and age-based vaccination in three districts in Tanzania. The study found that class-based delivery was generally cheaper at an estimated $9.76 per fully immunized girl and $1.3 million overall, excluding vaccine costs.

The second study, conducted by Raymond Hutubessy from the WHO and his colleagues, used the new Cervical Cancer Prevention and Control Costing tool during a five year planning period. The study estimated that the vaccine could be delivered at $12.40 for each fully immunized girl.

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like zombies B-)
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How American Samoa Avoided the Spanish Flu

How quick thinking by a U.S. official saved thousands of lives from disease in an American territory—despite its non-American counterpart being decimated.
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New Research Opens the Door to ‘Functional Cure’ for HIV

Medicine, Health Care New Research Opens the Door… Published: October 18, 2017.Released by Scripps Research Institute JUPITER, FL – Oct. 17, 2017 – In findings that open the door to a completely different approach to curing HIV infections, scientists from the Florida campus of The Scripps Research Institute (TSRI) have […]
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Tat inhibitor!
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South African egg output tumbles, jobs cut after avian flu

South African egg output tumbles, jobs cut after avian flu | Virology News | Scoop.it
Commercial egg production in South Africa has tumbled 17 percent and over 1,000 workers have lost their jobs in the wake of an outbreak of avian flu in June, industry experts said on Wednesday.
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HPV Vaccine Safe for Adult Women

HPV Vaccine Safe for Adult Women | Virology News | Scoop.it
Vaccines that ward off the cancer-linked human papillomavirus (HPV) are safe for adult women, according to a study of more than 3 million Scandinavians. The res
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Rotavirus vaccine could save lives of almost 500,000 children a year

Rotavirus vaccine could save lives of almost 500,000 children a year | Virology News | Scoop.it
Positive outcome of trials in Niger fuels hope that vaccine can protect children in sub-Saharan Africa and beyond from infection that causes often fatal diarrhoea
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Genetic characterization of novel reassortant H5N6-subtype influenza viruses isolated from cats in eastern China

Cats are susceptible to influenza A viruses and therefore may act as transmission vectors within households, posing a potential public health concern. Two novel reassortant H5N6 influenza viruses were isolated from cats in Zhejiang Province, Eastern China, in 2016. Both viruses were characterized by whole-genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis showed that these viruses received their genes from H5N6, H9N2, and H7N9 influenza viruses isolated from China. These H5N6 viruses were able to replicate in mice without prior adaptation. Our results show that continued circulation of these viruses could endanger humans.

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Great! First birds, then bats, now cats!
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Identification and genetic characterization of a novel circular single-stranded DNA virus in a human upper respiratory tract sample

Metagenomic analysis through high-throughput sequencing is a tool for detecting both known and novel viruses. Using this technique, a novel circular single-stranded DNA (ssDNA) virus genome was discovered in respiratory secretions from a febrile traveler. The virus, named human respiratory-associated PSCV-5-like virus (HRAPLV), has a genome comprising 3,018 bases, with two major putative ORFs inversely encoding capsid (Cap) and replicase (Rep) protein and separated by two intergenic regions. One stem-loop structure was predicted in the larger intergenic region (LIR). The predicted amino acid sequences of the Cap and Rep proteins of HRAPLV showed highest identity to those of porcine stool-associated circular virus 5 isolate CP3 (PoSCV 5) (53.0% and 48.9%, respectively). The host tropism of the virus is unknown, and further study is warranted to determine whether this novel virus is associated with human disease.

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Nigeria: Adewole - Three Cases of Monkey Pox Confirmed in Bayelsa, Lagos Free of Virus

Nigeria: Adewole - Three Cases of Monkey Pox Confirmed in Bayelsa, Lagos Free of Virus | Virology News | Scoop.it
Against palpable fear over the spread of monkey pox disease in Nigeria, the Minister of Health, Prof. Isaac Adewole, has declared Lagos State free from the virus while Bayelsa State has recorded about three confirmed cases after laboratory tests.
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Human papillomavirus vaccination of adult women and [lack of] risk of autoimmune and neurological diseases

Human papillomavirus vaccination of adult women and [lack of] risk of autoimmune and neurological diseases | Virology News | Scoop.it
Since 2006, human papillomavirus (HPV) vaccines have been introduced in many countries worldwide. Whilst safety studies have been reassuring, focus has been on the primary target group, the youn
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Flu Vaccine Fake News That Goes Viral During The Flu Season

Flu Vaccine Fake News That Goes Viral During The Flu Season | Virology News | Scoop.it

Winter is almost here, which means flu season is just around the corner. It also means that anti-flu vaccine misinformation will go viral again (pun inten
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Oral HPV Affects More Men Than Women

(Reuters Health) - Roughly one in nine U.S. men have oral infections of the cancer-causing human papillomavirus (HPV), more than triple the infection rat
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Findings add to evidence of association between Zika virus and Guillain-Barre syndrome

Findings add to evidence of association between Zika virus and Guillain-Barre syndrome | Virology News | Scoop.it
An examination of cases of Guillain-Barré syndrome in Puerto Rico identified Zika virus infection as a risk factor, according to a study published by JAMA.
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1 in 9 Men Have Oral HPV

1 in 9 Men Have Oral HPV | Virology News | Scoop.it
A new report reveals that about 1 in 9 men have an oral infection of human papillomavirus (HPV) in the United States.
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The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch 

The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch  | Virology News | Scoop.it
Use of dissolvable microneedle patches for influenza vaccination was well tolerated
and generated robust antibody responses.
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Worms, mice, and people share 'wasabi receptor' - Futurity

Worms, mice, and people share 'wasabi receptor' - Futurity | Virology News | Scoop.it
The finding that worms, flies, and humans share an ancient pain receptor could offer researchers new targets for pain-fighting drugs.
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So all of us would enjoy sushi??
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WHO supports the immunization of 874 000 people against yellow fever in Nigeria

WHO supports the immunization of 874 000 people against yellow fever in Nigeria | Virology News | Scoop.it
WHO supports the immunization of 874,000 people against yellow fever in Nigeria
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Monkeypox: Suspected cases in Nigeria spread to 11 states 

Monkeypox: Suspected cases in Nigeria spread to 11 states  | Virology News | Scoop.it

The monkeypox virus may have spread to 11 states with 74 suspected cases recorded, Minister of Health, Isaac Adewole, has said. Mr. Adewole made the disclosure in Abuja on Wednesday when he briefed State House correspondents on the outcome of the meeting of the Federal Executive Council, FEC. President Muhammadu Buhari chaired the meeting held at the State House Council Chamber, Abuja. The Federal Government on October 11 confirmed that 33 suspected cases of the virus were recorded in seven states. However, after samples of the suspected cases were sent for test at a WHO laboratory in Senegal, only three cases from Bayelsa tested positive. Monkeypox is a rare viral zoonosis (a virus transmitted to humans from animals) with symptoms in humans similar to those seen in the past in smallpox patients, although less severe. Smallpox was eradicated in 1980. However, monkeypox still occurs sporadically in some parts of Africa. The minister, who updated the Council on developments in respect of the outbreak, listed the affected States as Akwa Ibom, Bayelsa, Cross River, Delta, Ekiti, Enugu, Imo, Lagos, Nasarawa and Rivers as well as the FCT. “The Council also received an update on the state of the public health of the nation. We informed the council about the latest development in respect of the monkeypox virus outbreak. So far as of today, there are 74 suspected cases in 11 states of the country.

Ed Rybicki's insight:
Sinister thing is, people are accusing the government and the Army of spreading it via vaccination.
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Discovery of two small circular ssDNA viruses associated with the whitefly Bemisia tabaci

The complete genome sequences of two novel small circular DNA viruses isolated from sweet-potato whiteflies collected in Central-West (AdDF) and Southeast (AdO) regions of Brazil were determined by Next Generation Sequencing (NGS), and confirmed by cloning and Sanger sequencing. The genomes are 2,199 and 2,211 nt-long, respectively, encoding a putative coat protein (CP) and a replication-associated protein (Rep) and showing a genomic organization typical of viruses from the family Genomoviridae. Phylogenetic analysis with deduced amino acid sequences of Rep indicates that the virus from AdO is closely related to other members of the genus Gemycircularvirus, while the virus from AdDF is related to those of the genus Gemyduguivirus. These new genomoviruses are tentatively named bemisia-associated genomovirus AdO and bemisia-associated genomovirus AdDF.

Ed Rybicki's insight:
I would be willing to bet some serious money that this is why my good friend Hanokh Czosnek and colelagues have persistently claimed that TYLCV replicates in whiteflies: the promiscuity of Rep-DNA interactions among ssDNA viruses could allow low-level replication of the geminiviral genome by the genomovirus Rep??
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Protective immune response of oral rabies vaccine in stray dogs, corsacs and steppe wolves after a single immunization

In this study the safety and protective immunity of an oral rabies vaccine, based on the live, modified rabies virus strain VRC-RZ2, was examined in stray dogs (Canis Sp.), corsacs (Vulpes corsac) and steppe wolves (Canis lupus campestris). In the safety group (dogs, n=6; corsacs, n=3; wolves, n=3) which was vaccinated with a 10-times field dose/animal, no animals showed any signs of disease or changes in behavior or appetite during the period of clinical observation, similar to the animals in the negative control group. Saliva samples taken from animals prior and post (5th and 10th days) vaccination failed to demonstrate rabies virus antigen. Observations of immunogenicity in vaccinated carnivores (dogs, corsacs and wolves) during a 180 day period showed the titers of virus neutralizing antibodies (VNA) in the blood sera of vaccinated dogs to be within 0.59-1.37 IU/mL. On 14 days post vaccination (dpv), all the wild carnivores had detectable levels of neutralizing antibodies, with mean titers ranging from 0.50 ± 0.07 IU/mL (for wolves) to 0.59 ± 0.10 IU/mL (for corsacs). Weeks after vaccination, all the vaccinated wolves and corsacs had higher levels of neutralizing antibodies: 0.70 ± 0.10 – 0.71 ± 0.08 IU/mL at 30 dpv, 1.06 ± 0.08 – 1.28 ± 0.21 IU/mL at 60 dpv and 0.41 ± 0.09 – 047 ± 0.06 at 180 dpv. The highest level of VNA (˃1.0 IU/ml) was detected at 60 dpv, in all vaccinated animals. After challenge all vaccinated dogs remained healthy for 180 days. Control animals (unvaccinated dogs) developed symptoms of rabies on day 6 post administration of a virulent virus and died of rabies on days 11-13. Of note, the VNA titers in all the wild carnivores (corsacs and wolves) immunized with VRC-RZ2 were higher than 0.5 IU/ml (0.59 ± 0.11 IU/ml), even as early as 14 days post vaccination. These, presumably protective, titers of antibodies to rabies virus were present in the dogs and wild carnivores examined in this study for at least 180 days.

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Immunological aspects of rabies: a literature review

Rabies is a lethal disease caused by the neurotropic virus rabies virus (RABV), and it remains an important public health problem globally. It is known that the host immune response is important for c
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Bacteria? Virus? Fungi? Diagnosing Common Cannabis Diseases

Bacteria? Virus? Fungi? Diagnosing Common Cannabis Diseases | Virology News | Scoop.it
Just like any other crop cultivated, cannabis is subject to a wide range of pests and diseases that can distress your plants.
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I'm still looking for a cannabis mild mosaic virus B-)
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UBC researchers pull paper linking vaccine component to autism

'There was a screw-up' UBC researchers pull paper linking vaccine component to autism. Researchers from the University of British Columbia are retractin
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Rabies vaccine cost bites as dogs run wild

This raises concern over the availability of the rabies vaccine and the cost. New Vision TV offers analyzed news content on trending stories in Uganda, b
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Full-Genome Sequence of Porcine Circovirus type 3 recovered from serum of sows with stillbirths in Brazil

Transbound Emerg Dis. 2017 Oct 12. doi: 10.1111/tbed.12735. [Epub ahead of print]
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WHO validates elimination of mother-to-child transmission of HIV and syphilis in Cuba

Cuba today became the first country in the world to receive validation from WHO that it has eliminated mother-to-child transmission of HIV and syphilis.
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