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Forget popping vitamins, MEDITATION could stave off colds and flu

Forget popping vitamins, MEDITATION could stave off colds and flu | Virology News | Scoop.it
Adults who meditated or did moderately intense exercise for eight weeks suffered fewer colds than those who did nothing, according to a study from the University of Wisconsin–Madison.
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Virology News
Topical news snippets about viruses that affect people.  And other things. Like zombies B-)
Curated by Ed Rybicki
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Cow antibodies yield important clues for developing a broadly effective AIDS vaccine

Cow antibodies yield important clues for developing a broadly effective AIDS vaccine | Virology News | Scoop.it
Credit: IAVI LA JOLLA - Cows are leaving the pasture and entering the field...of HIV vaccine research. As outlined in a study published today in Nature, lead author Devin Sok, Director, Antibody Di..
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High-dose influenza vaccine leads to lower hospitalizations in nursing home residents

Electron microscopy of influenza virus. Credit: CDC In the largest nursing home study to date on the effect of a high dose (HD) flu vaccine, researchers found that vaccines with four times the antigen of standard flu (SD) vaccines significantly reduced the risk of respiratory and all-cause hospitalization during flu […]
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Only US company that makes yellow fever vaccine closes

Just one medical facility in New Hampshire has the vaccine in stock. Subscribe to WMUR on YouTube now for more: http://bit.ly/1lOjX9C Get more Mancheste
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Development of real-time and lateral flow dipstick recombinase polymerase amplification assays for rapid detection of goatpox virus and sheeppox virus

Development of real-time and lateral flow dipstick recombinase polymerase amplification assays for rapid detection of goatpox virus and sheeppox virus | Virology News | Scoop.it
Goatpox virus (GTPV) and sheeppox virus (SPPV), which belong to the Capripoxvirus (CaPV), are economically important pathogens of small ruminants. Therefore, a sensitive, specific and rapid diagnostic assay for detection of GTPV and SPPV is necessary to accurately and promptly control these diseases. Recombinase polymerase amplification (RPA) assays combined with a real-time fluorescent detection (real-time RPA assay) and lateral flow dipstick (RPA LFD assay) were developed targeting the CaPV G-protein-coupled chemokine receptor (GPCR) gene, respectively. The sensitivity of both CaPV real-time RPA assay and CaPV RPA LFD assay were 3 × 102 copies per reaction within 20 min at 38 °C. Both assays were highly specific for CaPV, with no cross-reactions with peste des petits ruminants virus, foot-and-mouth disease virus and Orf virus. The evaluation of the performance of these two assays with clinical sample (n = 107) showed that the CaPV real-time RPA assay and CaPV RPA LFD assay were able to specially detect SPPV or GTPV present in samples of ovine in liver, lung, kidney, spleen, skin and blood. This study provided a highly time-efficient and simple alternative for rapid detection of GTPV and SPPV.
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First vaccine to show protection against gonorrhoea

First vaccine to show protection against gonorrhoea | Virology News | Scoop.it
Exposure to the meningococcal group B vaccine during a New Zealand mass vaccination campaign was associated with a reduced likelihood of contracting gonorrhoea, compared with unvaccinated people, according to a new study of more than 14,000 people published in The Lancet. This is the first time that a vaccine has shown any protection against gonorrhoea, and may provide a new avenue for vaccine development.
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Given the rapid development of multiply-resistant strains, this is a really good development. 
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Researchers report advance in search for vaccine to fight CMV 

Researchers from Duke University School of Medicine and Tulane National Primate Research Center report findings in monkeys that demonstrates a vaccine approach for cytomegalovirus, or CMV, that appears to be capable of protecting the animal's fetus from infection.
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Associations of Oral α-, β-, and γ-Human Papillomavirus Types With Risk of Incident Head and Neck Cancer

Associations of Oral α-, β-, and γ-Human Papillomavirus Types With Risk of Incident Head and Neck Cancer | Virology News | Scoop.it
JAMA Oncol. 2016 Jan 21. doi: 10.1001/jamaoncol.2015.5504. [Epub ahead of print]
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Nigeria: U.S. Commits U.S.$4.3 Billion to Tackle HIV in Nigeria

Nigeria: U.S. Commits U.S.$4.3 Billion to Tackle HIV in Nigeria | Virology News | Scoop.it
The US government support for HIV/AIDS programmes in Nigeria totalled $4.3 billion between 2014 and 2016 with more than 700,000 patients treated in 2016 alone.
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H7N9 avian influenza: 12 more cases reported in China - Outbreak News Today

The Chinese National Health and Family Planning Commission announced an additional 12 human cases of avian influenza A(H7N9) from June 2 to 8. The eight male and four female patients, aged from 4 to 68, had onset from May 20 to June 3. Three of them are from Beijing, two each from Anhui, Chongqing and Henan, and … (via: trendolizer.com)
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The science behind the story: Following a cancer vaccine from concept to proof of concept 

The successful early-stage clinical trial of a personalized cancer vaccine for melanoma represents the culmination of almost a decade’s collaborative work to overcome challenges large and small.
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Column: 'Over half my patients, often with contagious illnesses, have to share a bed'

Column: 'Over half my patients, often with contagious illnesses, have to share a bed' | Virology News | Scoop.it
The scale of the HIV problem in Kenya’s Homa Bay County is enormous, writes Dr Eamonn Faller.
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Global Influenza Diagnostics Market Is Expected To Reach US$ 978.6 Mn By 2025 

Global Influenza Diagnostics Market Is Expected To Reach US$ 978.6 Mn By 2025  | Virology News | Scoop.it
New Market Research Reports Title “Global Influenza Diagnostics Market Is Expected To Reach US$ 978.6 Mn By 2025 – Credence Research” Has Been Added to Credenceresearch.com Report Database. According to the latest market report published by Credence Research, Inc.
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How this common virus [RSV] evades the immune system - Futurity

How this common virus [RSV] evades the immune system - Futurity | Virology News | Scoop.it
A new look at RSV could lead to treatments for the common, at times fatal, infection that sickens thousands of young children and elderly people each year.
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For 1st time, over half of people with HIV taking AIDS drugs

LONDON (AP) — For the first time in the global AIDS epidemic that has spanned four decades and killed 35 million people, more than half of all those infected with HIV are on drugs to treat the virus, the United Nations said in a report released Thursday. (via: trendolizer.com)
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Drug combo could repair fetal alcohol damage

Drug combo could repair fetal alcohol damage | Virology News | Scoop.it
"We have identified a potential treatment for alcohol spectrum disorder. Currently, there is none."
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HUUUUGE news for South Africa: we have the world's highest incidence of this problem.
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New, More Effective Flu Vaccine Delivered Using Dissolvable Microneedle Patch

New, More Effective Flu Vaccine Delivered Using Dissolvable Microneedle Patch | Virology News | Scoop.it
Researchers at Georgia State University have developed a more effective way of delivering influenza vaccines thanks to a dissolvable microneedle array and
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The effects of potato virus Y-derived virus small interfering RNAs of three biologically distinct strains on potato ( Solanum tuberosum) transcriptome

The effects of potato virus Y-derived virus small interfering RNAs of three biologically distinct strains on potato ( Solanum tuberosum) transcriptome | Virology News | Scoop.it

Potato virus Y (PVY) is one of the most economically important pathogen of potato that is present as biologically distinct strains. The virus-derived small interfering RNAs (vsiRNAs) from potato cv. Russet Burbank individually infected with PVY-N, PVY-NTN and PVY-O strains were recently characterized. Plant defense RNA-silencing mechanisms deployed against viruses produce vsiRNAs to degrade homologous viral transcripts. Based on sequence complementarity, the vsiRNAs can potentially degrade host RNA transcripts raising the prospect of vsiRNAs as pathogenicity determinants in virus-host interactions. This study investigated the global effects of PVY vsiRNAs on the host potato transcriptome. The strain-specific vsiRNAs of PVY, expressed in high copy number, were analyzed in silico for their proclivity to target potato coding and non-coding RNAs using psRobot and psRNATarget algorithms. Functional annotation of target coding transcripts was carried out to predict physiological effects of the vsiRNAs on the potato cv. Russet Burbank. The downregulation of selected target coding transcripts was further validated using qRT-PCR. The vsiRNAs derived from biologically distinct strains of PVY displayed diversity in terms of absolute number, copy number and hotspots for siRNAs on their respective genomes. The vsiRNAs populations were derived with a high frequency from 6 K1, P1 and Hc-Pro for PVY-N, P1, Hc-Pro and P3 for PVY-NTN, and P1, 3′ UTR and NIa for PVY-O genomic regions. The number of vsiRNAs that displayed interaction with potato coding transcripts and number of putative coding target transcripts were comparable between PVY-N and PVY-O, and were relatively higher for PVY-NTN. The most abundant target non-coding RNA transcripts for the strain specific PVY-derived vsiRNAs were found to be MIR821, 28S rRNA,18S rRNA, snoR71, tRNA-Met and U5. Functional annotation and qRT-PCR validation suggested that the vsiRNAs target genes involved in plant hormone signaling, genetic information processing, plant-pathogen interactions, plant defense and stress response processes in potato. The findings suggested that the PVY-derived vsiRNAs could act as a pathogenicity determinant and as a counter-defense strategy to host RNA silencing in PVY-potato interactions. The broad range of host genes targeted by PVY vsiRNAs in infected potato suggests a diverse role for vsiRNAs that includes suppression of host stress responses and developmental processes. The interactome scenario is the first report on the interaction between one of the most important Potyvirus genome-derived siRNAs and the potato transcripts.
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Always a pleasure to share good work from old friends B-)
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Multivalent footrot vaccine developed by May 2018 

Multivalent footrot vaccine developed by May 2018  | Virology News | Scoop.it
MEAT and Livestock Australia hoped to have a cross-reactive footrot vaccine to protect against all serotypes of the crippling sheep condition by May 2018, MLA managing director Richard Norton told breeders in Bendigo last night.
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For sheep, folks, for sheep...B-)
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Age dependent differences in the kinetics of γδ T cells after influenza vaccination

Age dependent differences in the kinetics of γδ T cells after influenza vaccination | Virology News | Scoop.it
Immunosenescence is a hallmark of the aging immune system and is considered the main cause of a reduced vaccine efficacy in the elderly. Although γδ T cells can become activated by recombinant influenza hemagglutinin, their age-related immunocompetence during a virus-induced immune response has so far not been investigated. In this study we evaluate the kinetics of γδ T cells after vaccination with the trivalent 2011/2012 northern hemisphere seasonal influenza vaccine. We applied multi-parametric flow cytometry to a cohort of 21 young (19–30 years) and 23 elderly (53–67 years) healthy individuals. Activated and proliferating γδ T cells, as identified by CD38 and Ki67 expression, were quantified on the days 0, 3, 7, 10, 14, 17, and 21. We observed a significantly lower number of activated and proliferating γδ T cells at baseline and following vaccination in elderly as compared to young individuals. The kinetics changes of activated γδ T cells were much stronger in the young, while corresponding changes in the elderly occurred slower. In addition, we observed an association between day 21 HAI titers of influenza A and the frequencies of Ki67+ γδ T cells at day 7 in the young. In conclusion, aging induces alterations of the γδ T cell response that might have negative implications for vaccination efficacy.
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So: this could be why old people are more at risk??
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Influenza A (H3N2) Variant Virus | Swine/Variant Influenza (Flu)

Information on H3N2 Variant Influenza A Virus - CDC
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Exposure to cold impairs interferon-induced antiviral defense

Exposure to cold impairs interferon-induced antiviral defense | Virology News | Scoop.it
It is commonly believed that exposure to low temperature increases susceptibility to viral infection in the human respiratory tract, but a molecular mechanism supporting this belief has yet to be disc
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So my mother WAS right: going out in the rain could make a cold worse....
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An important travel vaccine that is often forgotten: rabies!

Rabies is deadly but preventable. Rabies vaccination is worth discussing with your doctor prior to your next holiday. Rabies is found in the the mamma
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HIV/AIDS: Nigeria risks one million deaths in five years, NACA warns

HIV/AIDS: Nigeria risks one million deaths in five years, NACA warns | Virology News | Scoop.it
Nigeria risks losing about one million of its citizens to HIV if its government does not take control of the full sponsorship of the treatment, an official has said. The Director-General of the National Agency for the Control of AIDS, NACA, Sani Aliyu, said Nigeria must take full sponsorship of...
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MSF: HIV response in West and Central Africa will not succeed if key barriers remain unaddressed

MSF: HIV response in West and Central Africa will not succeed if key barriers remain unaddressed | Virology News | Scoop.it
African heads of state meet today in Addis Ababa to endorse the emergency catch-up plan led by UNAIDS to accelerate HIV treatment in West and Central Africa. Médecins Sans Frontières (MSF) reiterates its call for a clear roadmap and strong political commitment from affected governments and all international stakeholders, towards removing longstanding barriers and implementing proven simplified strategies that will boost lifesaving treatment for 4.7 million living with HIV not yet accessing antiretroviral therapy (ARV). Lower rates of HIV prevalence in the region’s 21 countries, ranging from two to 10 per cent, have long resulted in less attention and investment in its overall HIV response. Here, only 28 per cent of people and 20 per cent of children living with HIV have access to ARV, resulting in high numbers of deaths and an incidence outpacing treatment initiations.
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Recombinant Influenza Vaccine More Effective Than Standard Inactivated Vaccine

Recombinant Influenza Vaccine More Effective Than Standard Inactivated Vaccine | Virology News | Scoop.it
From BioPortfolio: A comparison trial conducted during the 2014–2015 flu season found a difference in efficacy.
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