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Forget popping vitamins, MEDITATION could stave off colds and flu

Forget popping vitamins, MEDITATION could stave off colds and flu | Virology News | Scoop.it
Adults who meditated or did moderately intense exercise for eight weeks suffered fewer colds than those who did nothing, according to a study from the University of Wisconsin–Madison.
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Virology News
Topical news snippets about viruses that affect people.  And other things. Like zombies B-)
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Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques

Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques | Virology News | Scoop.it
Author summary Maternal ZIKV infection in pregnancy is associated with severe fetal anomalies, including microcephaly. It has been shown that infection manifests differently in pregnancy than in the non-pregnant state, with prolonged maternal viremia. ZIKV is spread by mosquitos and through sexual contact and since its first detection in early 2015, has become endemic to the Americas. While much has been learned from studying infected human pregnancies, there are still many questions concerning transmission of ZIKV from mother to fetus. Investigating ZIKV infection in non-human primates could help answer these questions due to similarities in the immune system, and the tissues separating the fetus from the mother during pregnancy. Our study serves to model ZIKV transmission in early and late pregnancy, as well as study the effects of this infection on the fetus and mother at these different times in pregnancy. The data collected provides an important insight on ZIKV in pregnancy where the pregnancies have been monitored throughout the entire infection period until term, and suggests that vertical transmission may be very efficient, although severe fetal outcomes are uncommon.
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Germany Expected to Pass Vaccine Law

On May 26, the German health ministry said the country will pass a proposed law allowing kindergartens to notify authorities if parents don’t talk to thei
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Like Switzerland: everything that is not forbidden is compulsory! But that's a good thing.
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2 Doses of HPV Shot Enough to Prevent Genital Warts

2 Doses of HPV Shot Enough to Prevent Genital Warts | Virology News | Scoop.it
2 Doses of HPV Shot Enough to Prevent Genital Warts: Study, Latest Sexual Health News WEDNESDAY, May 24, 2017 (HealthDay News) -- New research supports the recent U.S. recommendation for two, rather than three, doses of the human papillomavirus (HPV) vaccine to protect against genital warts in preteens and teens. Investigators at Boston University Medical…
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We'll get down to one eventually...B-)
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The Virus Hunters: The Daunting Search for the Next Deadly Pathogen in the Congo

The Virus Hunters: The Daunting Search for the Next Deadly Pathogen in the Congo | Virology News | Scoop.it
In the Democratic Republic of the Congo, teams of researchers are busy looking for the next deadly virus. The odds are not in their favor.
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REALLY good article - quite sobering. And full of good ideas.....
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South Africans to develop a vaccine to Group B Streptococcus

Locals to develop a vaccine to curb infant meningitis
Taschica Pillay | 2017-05-02 09:09:35.0

This vaccine will be given to pregnant women to protect the unborn child. Group B Streptococcus infects children in their first month of life, when they are most vulnerable. File photo
Photograph by: MARIANA BAZO
A South African company will announce plans today to develop a vaccine to treat one of the leading causes of sepsis and meningitis in infants.
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The announcement will be made at the Innovation Effect Africa Conference at Durban's International Convention Centre.

The conference, convened by international nongovernmental organisation Path, the Bill and Melinda Gates Foundation, Leapfrog Investments, the New Partnership for Africa's Development and Wellcome Trust, brings together industry leaders to explore opportunities to advance African-led innovation to improve health, spur economic growth and end poverty.

Morena Makhoana, CEO of Biovac, the company at the forefront of the effort , said the Gates foundation was funding development.

"The partnership takes us into developing products locally rather than looking overseas. Hopefully when the product is successful we can manufacture the vaccine from scratch in South Africa."

He said clinical trials would begin in about four to five years.

Makhoana said it was the first time that the Gates foundation would fund vaccine development by an African company.
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Thousands of chickens, ducks die as bird flu hits DRC

Thousands of chickens, ducks die as bird flu hits DRC | Virology News | Scoop.it
Authorities declare quarantine against movement of chicken and ducks - Anadolu Agency
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It's not just Ebola. Or yellow fever. Or monkeypox....
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U.S. HIV Incidence and Transmission Goals, 2020 and 2025

U.S. HIV Incidence and Transmission Goals, 2020 and 2025 | Virology News | Scoop.it
The recently updated U.S. National HIV/AIDS Strategy sets key HIV prevention and care
targets for 2020, but the trajectory of the epidemic remains unclear. Authors modeled
HIV incidence, prevalence, and mortality for the U.S. over 10 years to determine whether
an ambitious trajectory toward “ending AIDS” by 2025 would be achievable.
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'Inextricably linked' anti-vaccine and anti-GMO movements cause preventable suffering 

'Inextricably linked' anti-vaccine and anti-GMO movements cause preventable suffering  | Virology News | Scoop.it
he Organic Consumers Association an anti-GMO lobby group largely funded by the “natural food” and organic industries. ... The group is an active and visibl
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GREAT cartoon!
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New Zealander of the Year Dr Lance O'Sullivan storms stage at anti-vaccine film screening

New Zealander of the Year Dr Lance O'Sullivan storms stage at anti-vaccine film screening | Virology News | Scoop.it
"Your presence here will cause babies to die," Dr Lance O'Sullivan told the moviegoers.
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Go Kiwi!
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Study identifies cost-effective ways to combat HIV risk among intravenous drug users - Virology

With the abuse of opioids on the rise in the United States, Stanford University researchers are concerned that increased HIV transmission from shared needles won’t be far behind. Source link
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Influenza vaccination modifies disease severity among community-dwelling adults hospitalized with influenza

Conclusions: Influenza vaccination during 2013−14 influenza season attenuated adverse outcome among adults that were hospitalized with laboratory-confirmed influenza.
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Vaccinate!!  OK??
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This Week in HIV Research: Vitamin D May Protect Against HIV; and Protease Inhibitor Monotherapy

This Week in HIV Research: Vitamin D May Protect Against HIV; and Protease Inhibitor Monotherapy | Virology News | Scoop.it
This week, a study examines how two precursor forms of vitamin D may help protect against HIV infection. Another study supports the idea of proteas
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What is the deadly 'Brexit virus' and how can you avoid catching it?

What is the deadly 'Brexit virus' and how can you avoid catching it? | Virology News | Scoop.it

Brexit may not have happened officially just yet, but thousands of people in the UK have already been struck down by what’s being called the ‘Brexit virus’. A new strain of hepatitis E (HEV) which has been linked to pig farms in continental Europe has invaded Britain, health officials say. 

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So no European sossies for true Brits, then??
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Imams in U.S. take on the anti-vaccine movement during Ramadan

Somali Americans suffering a measles outbreak hear a call to faith in medicine.
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Scientists jump hurdle in HIV vaccine design

Scientists jump hurdle in HIV vaccine design | Virology News | Scoop.it
Scientists at The Scripps Research Institute (TSRI) have made another important advance in HIV vaccine design. The development was possible thanks to previous studies at TSRI showing the structures of a protein on HIV's surface
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Detection of alpha- and betacoronaviruses in rodents from Yunnan, China

Detection of alpha- and betacoronaviruses in rodents from Yunnan, China | Virology News | Scoop.it
Rodents represent the most diverse mammals on the planet and are important reservoirs of human pathogens. Coronaviruses infect various animals, but to date, relatively few coronaviruses have been identified in rodents worldwide. The evolution and ecology of coronaviruses in rodent have not been fully investigated. In this study, we collected 177 intestinal samples from thress species of rodents in Jianchuan County, Yunnan Province, China. Alphacoronavirus and betacoronavirus were detected in 23 rodent samples from three species, namely Apodemus chevrieri (21/98), Eothenomys fidelis (1/62), and Apodemus ilex (1/17). We further characterized the full-length genome of an alphacoronavirus from the A. chevrieri rat and named it as AcCoV-JC34. The AcCoV-JC34 genome was 27,649 nucleotides long and showed a structure similar to the HKU2 bat coronavirus. Comparing the normal transcription regulatory sequence (TRS), 3 variant TRS sequences upstream the spike (S), ORF3, and ORF8 genes were found in the genome of AcCoV-JC34. In the conserved replicase domains, AcCoV-JC34 was most closely related to Rattus norvegicus coronavirus LNRV but diverged from other alphacoronaviruses, indicating that AcCoV-JC34 and LNRV may represent a novel alphacoronavirus species. However, the S and nucleocapsid proteins showed low similarity to those of LRNV, with 66.5 and 77.4% identities, respectively. Phylogenetic analysis revealed that the S genes of AcCoV-JC34, LRNV, and HKU2 formed a distinct lineage with all known coronaviruses. Both alphacoronaviruses and betacoronaviruses were detected in Apodemus chevrieri in the Yunnan Province of China, indicating that Apodemus chevrieri is an important host for coronavirus. Several new features were identified in the genome of an Apodemus chevrieri coronavirus. The phylogenetic distance to other coronaviruses suggests a variable origin and evolutionary route of the S genes of AcCoV-JC34, LRNV, and HKU2. These results indicate that the diversity of rodent coronaviruses is much higher than previously expected. Further surveillance and functional studies of these coronaviruses will help to better understand the importance of rodent as host for coronaviruses.
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Rats. Rats, everywhere. Evidently, so too coronaviruses
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Cannabis extract cuts seizures for epilepsy patients

Cannabis extract cuts seizures for epilepsy patients | Virology News | Scoop.it
The first large-scale clinical trial of a cannabis derivative known as cannabidiol shows it was able to cut the frequency of severe epileptic seizures by 39 percent, researchers said Wednesday.
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OK: so I should be an old mouse with epilepsy to derive maximum benefit?? B-)
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Inovio HIV Vaccine Elicits Nearly 100% Immune Response Rates In A Clinical Study

PLYMOUTH MEETING, Pa., May 24, 2017 (GLOBE NEWSWIRE) -- Inovio Pharmaceuticals, Inc. (NASDAQ:INO) today announced that its HIV vaccine, PENNVAX®-GP, produced amongst the highest overall levels of immune response rates (cellular and humoral) ever demonstrated in a human study by an HIV vaccine. The vaccine candidate, PENNVAX-GP, consists of a combination of four HIV antigens designed to cover multiple global HIV strains and generate both an antibody (humoral) immune response as well as a T cell (cellular) immune response to both potentially prevent and treat HIV.

These preliminary results are from a study supported by the HIV Vaccine Trials Network (HVTN) and the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) in collaboration with Inovio. The study evaluated a four-dose regimen of PENNVAX-GP DNA vaccine administered by intradermal (ID) or intramuscular (IM) administration in combination with a DNA encoded immune activator, IL-12 (INO-9012). Overall, 71 of 76 (93%) evaluable vaccinated participants showed a CD4+ or CD8+ cellular immune response to at least one of the vaccine antigens (env A, env C, gag, or pol). Similarly, 62 of 66 (94%) evaluated participants demonstrated an env specific antibody response. None of the placebo recipients (0 of 9; 0%) demonstrated either a cellular or an antibody response in the study. Notably, amongst the participants receiving PENNVAX-GP vaccine and IL-12 with intradermal immunization, 27 of 28 (96%) participants demonstrated a cellular response and 27 of 28 (96%) demonstrated an HIV env specific antibody response.
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Scientists Have Reversed Age-Related Blindness by Deliberately Infecting Eyes With a Virus

A small and preliminary clinical trial has found that injecting a common cold-like virus into the eyes of age-related macular degeneration (AMD) patients - one of the leading causes of blindness in the US - can halt and even reverse th
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I think I may need me some of that....
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Vendor With Bird Flu Prompts China to Close Poultry Markets 

Vendor With Bird Flu Prompts China to Close Poultry Markets  | Virology News | Scoop.it
China will shutter poultry markets in a district of southwestern Sichuan province after a man fell ill with the H7N9 bird flu, state-owned China News Service reported Sunday.


The 44-year-old man sold live poultry at a farmers market, China News reported, citing officials in Zigong city.


Poultry markets in Zigong's Ziliujing district will be closed starting from midnight Monday, the report said.


Cases of bird flu have been unusually high for China since last year, with three times more fatalities from H7N9 in the first four months of the year than in all of 2016, although deaths fell in April for the third ...read more
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CDC prepares new H7N9 vaccine as human cases spike

The CDC has begun preparing a new avian influenza A(H7N9) vaccine amid a spike in cases in China and evidence that the deadly virus has split into two strains, including one that does not seem to be susceptible to existing vaccines.A record 460 human cases of H7N9 have been reported since Oct. 1 in China — more than 36% of the overall number of 1,258 cases that have been seen in the region
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Zika virus hit earlier than thought in Brazil, Florida

Zika virus hit earlier than thought in Brazil, Florida | Virology News | Scoop.it
Studies using gene sequencing equipment to trace the path of Zika through the Americas show the virus arrived a year before the first case was detected in Brazil, and several months before it was first reported in Florida. The findings, published in three different papers in the journal Nature, are drawn from nearly 200 Zika virus genome sequences collected from infected individuals …
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World Health Organization gets first leader from Africa

World Health Organization gets first leader from Africa | Virology News | Scoop.it
Ethiopia’s Tedros Adhanom Ghebreyesus to head agency amid calls for reform.
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Patterns of prevalent HPV and STI co-infections and associated factors among HIV- young South African women

OBJECTIVE:
To estimate the prevalence and describe the patterns of concurrent human papillomavirus (HPV) and STIs and associated factors among HIV-negative young Western Cape, South African women participating in the Efficacy of HPV Vaccine to Reduce HIV Infection (EVRI) trial.
METHODS:
HIV-negative women aged 16-24 years old were enrolled in the EVRI trial (NCT01489527) and randomised to receive the licensed four-valent HPV vaccine or placebo. At study entry, participants were clinically evaluated for five STIs: herpes simplex virus type 2 (HSV-2), chlamydia, gonorrhoea, syphilis and disease-causing HPV genotypes (6/11/16/18/31/33/35/39/45/51/52/56/58/59/68). Demographic and sexual history characteristics were compared among women with STI co-infections, single infection and no infection using Pearson χ2 and Mann-Whitney tests. ORs were calculated to evaluate factors associated with STI co-infection prevalence.
RESULTS:
Among 388 young women, STI co-infection prevalence was high: 47% had ≥2 concurrent STIs, 36% had a single STI and 17% had none of the five evaluated STIs. HPV/HSV-2 (26%) was the most prevalent co-infection detected followed by HPV/HSV-2/Chlamydia trachomatis (CT) (17%) and HPV/CT (15%). Co-infection prevalence was independently associated with alcohol use (adjusted OR=2.01, 95% CI 1.00 to 4.06) and having a sexual partner with an STI (adjusted OR=6.96, 95% CI 1.53 to 30.08).
CONCLUSIONS:
Among high-risk young women from underserved communities such as in Southern Africa, a multicomponent prevention strategy that integrates medical and behavioural interventions targeting both men and women is essential to prevent acquisition of concurrent STI infections and consequent disease.
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Why GM mosquitoes might not work against malaria - Futurity

Why GM mosquitoes might not work against malaria - Futurity | Virology News | Scoop.it
Using CRISPR to genetically alter insects that harm crops or carry disease—such as malaria—may not be as easy as once thought.
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