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Scooped by Ed Rybicki onto Virology News |
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At least 51 percent of sex workers in Rwanda are infected with HIV, according to the latest report by the Rwanda Biomedical Centre (RBC).The research was carried out in all provinces of the country at the different sex workers' hot spots, according to Dr Sabin Nsanzimana, the coordinator of HIV and STIs Care and Treatment department.
The research was the first of its kind conducted by Rwanda Biomedical Centre, according to Dr Nsanzimana.
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"Transgenic plants present enormous potential as a cost-effective and safe platform for large-scale production of vaccines and other therapeutic proteins. A number of different technologies are under development for the production of pharmaceutical proteins from plant tissues. One method used to express high levels of protein in plants involves the employment of plant virus expression vectors. Plant virus vectors have been designed to carry vaccine epitopes as well as full therapeutic proteins such as monoclonal antibodies in plant tissue both safely and effectively. Biopharmaceuticals such as these offer enormous potential on many levels, from providing relief to those who have little access to modern medicine, to playing an active role in the battle against cancer. This review describes the current design and status of plant virus expression vectors used as production platforms for biopharmaceutical proteins."
And of course, let it not be forgotten that our group has pioneered the use of mastreviruses in this regard: maize streak virus in 1999-2001, and bean yellow dwarf in 2010 and since. Investigation of the potential of maize streak virus to act as an infectious gene vector in maize plants.
High level protein expression in plants through the use of a novel autonomously replicating geminivirus shuttle vector.
...not to mention a treatise on ssDNA virus vectors in plants:
Virus-Derived ssDNA Vectors for the Expression of Foreign Proteins in Plants. Via Hiroyuki Mizumoto, Chris Upton + helpers Delete the scoop?
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