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Major breakthrough in HIV prevention

Major breakthrough in HIV prevention | Virology News | Scoop.it
MELBOURNE researchers have developed cows' milk that can defend human cells against HIV.

Lead researcher, University of Melbourne's Marit Kramski said they vaccinated pregnant cows - which cannot contract human immunodeficiency virus - with an HIV protein [Env?] and studied the first milk produced by the cow after birth.

HIV cases in Australia on the rise

Dr Kramski said this first milk, called colostrum, produced milk high in antibodies to protect its newborn against disease.

The researchers were able to inhibit the virus from infecting cells when "combing the virus cells with milk" [sic - I think they mean combining the virus with milk containing antibodies].

 

I think this is very interesting, and has potential for trial in monkeys - not humans, because there is the little problem of the antibodies that would go into a virucidal cream being from cows - meaning they would elicit an immune response, unlike the humanised anti-HIV monoclonals being made in plants by the Fraunhofer Institute.

 

Still, using cow's milk is an inventive thing to do - and sounds like a very cheap source of antibodies.  Except that colostrum is ONLY produced immediately after birth of a calf, so it will nothing like as cheap as milk.

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Virology News
Topical news snippets about viruses that affect people.  And other things. Like zombies B-)
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Pertussis and influenza immunisation during pregnancy: a landscape review

Immunisation during pregnancy is a relatively new strategy, and is currently limited to tetanus, pertussis, and influenza vaccines. None of these vaccines were developed specifically for use in pregnancy, but they provide an effective method of protecting mothers and young infants. In response to increases in pertussis morbidity and mortality among young infants, several countries have recommended universal tetanus, diphtheria, and acellular pertussis immunisation during pregnancy. Similarly, many countries recommend influenza immunisation during pregnancy to reduce the risk of disease for mother and infant. Although scientific evidence to support maternal immunisation against pertussis and influenza is rapidly accumulating, important knowledge gaps remain that need to be addressed by future research, which we have highlighted in this Series paper.

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HPV control and resistance in the Middle East and north Africa

Islamic countries, and countries with more conservative sexual views based on religion in general, should implement educational projects in government-organised programmes. As we mentioned in our original Correspondence,2 the organisation of intervention policies based on awareness campaigns can be a very effective first step in the control of cervical cancer caused by HPV. However, a point that we would like to stress once more is that acceptance and implementation of these programmes, and in effect also vaccines, can be faced with difficulties because of stigmatisation that is based on religious and traditional values.
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Improving communication about viral hepatitis in Africa

Considerable challenges hamper effective communication between health workers and people with chronic hepatitis. A first step in addressing the burden of chronic hepatitis in sub-Saharan Africa would be to improve training of health workers in understanding viral hepatitis. A second step would be to create more effective, meaningful communication strategies for health workers to use with patients. Development of these measures through anthropological research will set crucial foundations for treatment scale-up in low-income and middle-income countries, which can contribute to the global elimination of viral hepatitis.

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Africa health: Rotavirus vaccine could save 500,000 children a year

Africa health: Rotavirus vaccine could save 500,000 children a year | Virology News | Scoop.it
The Indian vaccine, which protects against gastroenteritis caused by rotavirus, was tested in Niger.
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Polio Vaccine Pioneer, Julius S. Youngner, Sc.D., Dies at 96 

<strong></strong> Julius S. Youngner, Sc.D., a world-renowned virologist best known for his contributions to the development of the first effective polio vaccine alongsi
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Experimental Vaccine Lowers Cholesterol Levels in Mice

A promising new study on mice suggests that a vaccine may one day be able to help fight cholesterol buildup in the arteries. Study co-author Gunthe
Ed Rybicki's insight:
I need me some of that!
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65 Persons Under Surveillance As Lassa Fever Kills Student Nurse In Nigeria

65 Persons Under Surveillance As Lassa Fever Kills Student Nurse In Nigeria | Virology News | Scoop.it

Speaking with newsmen in Awka, the Director of Public Health, State Ministry of Health, Dr Emmanuel Okafor, said that the deceased (name withheld) was a student in one private nursing school in Nkpor, Idemili North. Okafor said that the lady was admitted at the Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka, on June 11. According to him, she was immediately transferred to the General Hospital, Irua, in Edo for diagnosis where she died on June 17. “She was initially admitted at Amaku in Awka before she was transferred to Irua and was placed on admission there. “She was bleeding from the gums, nostril and vagina and was confirmed Lassa Fever victim in Irua. “The moment it was confirmed that she had Lassa fever, we started contacts tracing. “As of now, we have about 65 we are following up, two of them have developed fever and their samples have been taken to Irua. “We are still tracking others and we have advised them on what to do to ensure they do not transfer it to their loved ones,” he said.

Ed Rybicki's insight:
Nearly as bad as the Ebola outbreak in Congo - and guess which gets the headlines? Every year, Lassa fever kills people in Nigeria and its neighbours.
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Inovio's HPV Immunotherapy Moves to Phase III, Stock Rises

Inovio's HPV Immunotherapy Moves to Phase III, Stock Rises | Virology News | Scoop.it
Inovio Pharmaceuticals, Inc 's INO shares rose over 10% after the company initiated a pivotal phase III REVEAL study to evaluate the safety and.
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Anti-vaccine activists spark a US state’s worst measles outbreak in decades

Anti-vaccine activists spark a US state’s worst measles outbreak in decades | Virology News | Scoop.it
The largest measles outbreak in nearly 30 years has hit Minnesota, with the spread of anti-vaccine attitudes being blamed.
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Cannabis Treats HPV Vaccine Side Effects, Study Suggests

Cannabis Treats HPV Vaccine Side Effects, Study Suggests | Virology News | Scoop.it
Greenmedinfo.com - Natural Health Resource - The world's most widely referenced, open access, natural medicine database, with 30,000+ study abstracts and growing daily
Ed Rybicki's insight:
And even if it doesn't, it should leave you feeling better B-)
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Nigerian-Made-Vaccine: Nigeria to get first batch in 2019

Nigerian-Made-Vaccine: Nigeria to get first batch in 2019 | Virology News | Scoop.it
It appears all is set for Nigeria, West Africa’s biggest economy, to get delivery of her first set of locally produced vaccine in July 2019, beginning with the drugs against Yellow fever, Tet…
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Hepatitis–E outbreaks due to the supply of highly contaminated water

The doctors have confirmed outbreak of Hepatitis- E at Ahmadabad village of south Kashmir’s Kulgam District due the supply of highly contaminated water to the inhabitants.
Ed Rybicki's insight:
Hep E: the OTHER infectious hepatitis virus
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Canine influenza questions? AVMA has answers - All Pet Posts

Canine influenza questions? AVMA has answers - All Pet Posts | Virology News | Scoop.it
A recent outbreak of canine influenza has been reported in the Southeastern United States.  -More- 
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Maternal immunisation: collaborating with mother nature

Maternal immunisation: collaborating with mother nature | Virology News | Scoop.it
Maternal immunisation has the potential to substantially reduce morbidity and mortality from infectious diseases after birth. The success of tetanus, influenza, and pertussis immunisation during pregnancy has led to consideration of additional maternal immunisation strategies to prevent group B streptococcus and respiratory syncytial virus infections, among others. However, many gaps in knowledge regarding the immunobiology of maternal immunisation prevent the optimal design and application of this successful public health intervention. Therefore, we did an innovative landscape analysis to identify research priorities. Key topics were delineated through review of the published literature, consultation with vaccine developers and regulatory agencies, and a collaborative workshop that gathered experts across several maternal immunisation initiatives—group B streptococcus, respiratory syncytial virus, pertussis, and influenza. Finally, a global online survey prioritised the identified knowledge gaps on the basis of expert opinion about their importance and relevance. Here we present the results of this worldwide landscape analysis and discuss the identified research gaps.

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Zika enhancement: a reality check

In northeast Brazil, dengue seropositivity is high but is not homogenous in the population.14 It is not known whether cases of congenital Zika syndrome occurred preferentially in women with previous dengue infection or whether cases cluster in regions with greater dengue seropositivity. Additionally, the situation might be much more complex because of the presence of yellow fever vaccination in the area. A spatial analysis study15 showed that the risk of congenital Zika syndrome in northeast Brazil clustered in regions where yellow fever vaccination rates were the lowest. Epidemiological evidence correlating sequential dengue virus–Zika virus infections in individuals with different Zika virus clinical syndromes compared with matched controls should be sought expeditiously. Dengue virus ADE of Zika virus infections, if real, will have profound implications for the design, testing, and delivery of Zika virus and dengue virus vaccines.

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Health Ministry to provide free HPV vaccine to Thai children

Health Ministry to provide free HPV vaccine to Thai children | Virology News | Scoop.it
BANGKOK – The Permanent Secretary of the Public Health Ministry disclosed that free HPV vaccine will be distributed to Thai children this July to maximize the prevention of rectal cancer in Thailand next year. Public Health Ministry Permanent Secretary Sophon Mekthon said the Ministry of Public Health’s objective is to make sure Thai people are …
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Zimbabwe: Avian Influenza - Govt Remains On High Alert

[The Herald] Government is in the process of mounting a risk based survey of the wild bird population to establish possible primary source of the Avian
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On the front lines of Russia's 'staggering' HIV epidemic

On the front lines of Russia's 'staggering' HIV epidemic | Virology News | Scoop.it
Anna Alimova works on the front lines of Russia's growing HIV epidemic. On a Friday night, the mother of two with a shock of bright pink hair stands outside a 24-hour pharmacy in a leafy Moscow neighborhood. She cheerfully offers plastic bags full of clean syringes to Russians dashing into and out of the store. "Mostly drug users have hepatitis," she says. "And many of them have HIV." According to the United Nations' UNAIDS program, Russia had the third-highest number of new HIV infections globally in 2015, behind South Africa and Nigeria. Russian government statistics show that more tha
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Red Meat Market in Slump Over Iran Congo Fever Outbreak

Red Meat Market in Slump Over Iran Congo Fever Outbreak | Virology News | Scoop.it

The spread of the Crimean-Congo hemorrhagic fever in Iran has caused serious concern among Iranians, as many refrain from buying red meat. “After the spread of the disease, people refuse to buy red meat, which has led to a slump in sheepmeat sales,” chairman of Sheepmeat Union, Ali Asghar Maleki, was quoted as saying by Mehr News Agency. Following the decline in demand, sheepmeat prices have fallen by 20,000 rials ($0.5) per kilogram, he added. Maleki warned of more disruption in the market, if the trend continues. CCHF is a widespread tick-borne viral disease that is now endemic in Africa, the Balkans, the Middle East and Asia. Symptoms include fever, muscle pain, dizziness, neck pain and stiffness, backache, headache, sore eyes and photophobia.

Ed Rybicki's insight:
That's a novel side effect of CCHFV reports?? Like Lassa, like Hepatitis E - we need vaccines!!
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Hepatitis E outbreak in Niger: 876 suspected cases

In southeastern Niger, the hepatitis E outbreak declared two months ago is particularly affecting pregnant women. Of the 186 women admitted to the main maternal
Ed Rybicki's insight:
It's not just the charismatic viruses: sometimes neglected not-so-bad-sounding viruses can kill you. Especially if you're a woman, and pregnant.
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The most recent news on Canine Influenza

The most recent news on Canine Influenza | Virology News | Scoop.it
You may have been hearing about canine influenza, or dog flu, in the news recently and we would like to provide you the most current information. 
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Stopping Influenza with Flu-Glue – Institute for Protein Design

Today, a multidisciplinary team of researchers at the University of Washington, Fred Hutch, and The Scripps Research Institute published in Nature Biotechnology the computational design of a trimeric influenza-neutralizing protein that binds extremely tightly to the H3 hemagglutinin of 1968 Hong...
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I thought antibodies did that already??
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This new vaccine design could potentially lead to one for HIV

This new vaccine design could potentially lead to one for HIV | Virology News | Scoop.it
A new approach to vaccine design could lead to one for HIV, say researchers, who have tested their work in monkeys.
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A sex worker's view on South Africa's latest plans to beat HIV

A sex worker's view on South Africa's latest plans to beat HIV | Virology News | Scoop.it
South Africa has launched a plan to tackle HIV, TB and sexually transmitted infections -- but much depends on its implementation over the next five years.
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Youth Action in Malawi targets HIV+ youth 

Youth Action in Malawi targets HIV+ youth  | Virology News | Scoop.it
Youth Action in Malawi (Yam), a non-governmental organisation based in Rumphi, has reiterated its commitment to reaching out to youths, especially those who are HIV positive. Yam Executive Director, Bright Mfune, said in an interview that they have secured piglets which will be distributed to youths living with HIV in Mhuju Zone, Rumphi, after multiplication.…
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