Halite is one of the most extreme environments to support life. From the drought of the Atacama Desert to salt deposits up to Permian in age and 2000 meters in burial depth, live microbes have been found. Because halite is geologically stable and impermeable to ground water, the microbes allegedly have a syndepositional origin, making them the oldest organisms known to live on Earth. Recently, our understanding of the microbial diversity inside halite has broadened, and the first genome sequences of ancient halite-buried microbes are now available. The secrets behind prolonged survival in salt are also starting to be revealed.
Virology Journal is now inviting submissions for a new thematic series on “The interplay between the host and HSV-1 infection”. Edited by Chunfu Zheng (Soochow University, China), the collection welcomes research and review articles, and will also include specially commissioned topical reviews, written by leaders in the field.
Herpes simplex virus type 1 (HSV-1) is a typical human-restricted pathogen, which is carried by 50-90% of the population worldwide, with higher frequencies in developing countries. HSV-1 is well known for its ability to establish a lifelong latent infection in neurons and trigger reactivation and lytic infection, mainly in epithelial or mucosal cells.
Although HSV-1 was identified over 100 years ago, the battle between HSV-1 and the host continues, as there is no vaccine yet available, and HSV-1 is still one of the major infectious diseases worldwide.
We will consider articles covering the interplay between the host and HSV-1 infection, including but not limited to:
Virus-host interactionCellular responses to viral infectionPathogenesis and immunity
The aim for this thematic series is to help us not only improve our knowledge of virus-host interactions but also develop novel antiviral approaches and vaccines against HSV-1 infection.
The deadline for submissions is April 30th 2016. To submit your manuscript, please use our online submission system, and indicate in your cover letter that you would like the manuscript to be considered for this thematic series. If you would like to enquire about the suitability of a manuscript for consideration, please email a pre-submission enquiry firstname.lastname@example.org.
In the past week, the world has mobilised to tackle the latest threat to global health security—Zika virus, now spreading rapidly in the Americas. Udani Samarasekera and Marcia Triunfol report.
Worldwide concern over Zika virus (panel) and its temporal and geographical association with clusters of birth and neurological conditions escalated this week, with WHO declaring a Public Health Emergency of International Concern.
A transmembrane protein receptor that is critical for adeno-associated virus infection has been identified through an unbiased, genome-wide screen. Its role in viral entry could potentially be harnessed to develop enhanced gene therapy vectors and better animal models of human disease.
Homeopathy is an alternative medicine, which means a few things. It means it’s not medicine, it’s an alternative; it means it’s seen by many as somehow better and healthier than modern medicines; and it means that people are incredibly emotional in their support for it. I’ve received death threats pretty much every time I’ve ever written …
(CNN) Vaccines and antibiotics have made many infectious diseases a thing of the past; we’ve come to expect that public health and modern science can conquer all microbes. But nature is a formidable adversary. And Zika is our newest threat, particularly to pregnant women.
New, unfamiliar and mysterious threats to our health are scary. At the Centers for Disease Control and Prevention — where we identify, on average, one new health threat each year — we work around the clock with an approach that prioritizes finding out what we need to know as fast as we can to protect Americans.
The CDC has some of the world’s leading experts both in diseases spread by mosquitoes and in fetal abnormalities. We get the facts, base actions on science, tell people what we know when we know it and what we are doing to add to our knowledge, and act to protect Americans today as effectively as possible.
WINNIPEG, Manitoba, Jan 28 (Reuters) - A vaccine for the Zika virus, which has been linked to severe birth defects in thousands of infants, could be ready for emergency use before year-end, one of its lead developers said on Thursday, a timetable...
Until recently, anthropologists drew the human family tree in the same way that my 10-year-old son solves a maze. He finds it much easier to work from the end to the beginning, because blind alleys lead with depressing sameness away from the start...
Ed Rybicki's insight:
We all of us, brothers and sisters...even you Denisovans!
February 3, 2016 | Just over a year ago, Bio-IT World spoke to microbiologist Nick Loman about the recently released MinION DNA sequencer. The three-inch-long device, made by Oxford Nanopore Technologies of the UK, can read DNA in real time on a laptop, and Loman’s lab at the University of Birmingham was one of the first to receive one. Like many other early adopters we spoke to at the time, Loman was itching to try the MinION in real-world clinical contexts, following the genetic traces of an infection as it develops.
A small protein molecule, engineered through computer design, protects against diverse strains of influenza in mice. Its preventive and therapeutic power does not depend on the animals’ own immune response to viral infection. These findings, from a multi-institutional study led by UW Medicine researchers in Seattle, are reported Feb. 4 in PLOS Pathogens. The researchers are trying to address the public health need for better methods to keep flu at bay. Vaccinations can deter flu infections, but they are strain-specific. Flu viruses are notorious for forming new genetic subtypes that can evade vaccines and acquire resistance to antiviral medications.
The Lancet Zika virus resource centre brings together the best evidence from across The Lancet family of journals—offered with free access—to assist researchers, policy makers, and health workers, in understanding the effects of the outbreak and how best to respond. Find out more about Zika virus in thisSpecial Report.
Colossal microbes taking over the world sounds like a B-movie plot, rather than the business plan of a stuffed toy manufacturer. We asked Drew Oliver, the creator and CEO of Giant Microbes, about how the company came about, how their products have been received and his plans for the future.
The world is once again asking scientists and drugmakers to come up rapidly with a vaccine for a viral disease that, in the latest case, few people had heard of until a few weeks ago, and even fewer feared.
Krishna Ella never expected to be holding the key to fighting a new global health emergency. Yet, his Indian firm—Bharat Biotech—has become the first to ready two vaccine candidates against the rapidly spreading Zika virus, which has already infected millions of people in Latin America. Zika doesn't cause much harm to adults. Most of the infected individuals...
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