Virology and Bioi...
Follow
Find
57.4K views | +11 today
Virology and Bioinformatics from Virology.ca
Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure
Your new post is loading...
Your new post is loading...
Rescooped by Chris Upton + helpers from Virology News
Scoop.it!

One Of My Favorite Charts On The Power Of Vaccines

One Of My Favorite Charts On The Power Of Vaccines | Virology and Bioinformatics from Virology.ca | Scoop.it
I'm posting this because I found the graphic in a file folder on my computer and didn't want to lose it. It's originally from my profile of Bill Gates from last year's Forbes Power List issue.

Via Ed Rybicki
more...
Scooped by Chris Upton + helpers
Scoop.it!

Virus Musings

Lessons from Schmallenberg (virus)

Whilst I haven't spoken to one, being a UK sheep farmer at the moment can't be much fun. Schmallenberg virus (SBV) is robbing farmers of lambs as well as being an altogether disturbing and unpleasant experience. How long it remains an issue will only become apparent with time. It's worth looking at whether this outbreak of SBV represents a sign of what's to come.

more...
No comment yet.
Scooped by burkesquires
Scoop.it!

Why the Flu Is So Relentless, and How Technology Might Help

Why the Flu Is So Relentless, and How Technology Might Help | Virology and Bioinformatics from Virology.ca | Scoop.it
Researchers are developing quick-brew vaccines and ones that catch multiple strains of flu.
more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Translational Bioinformatics: PLOS Computational Biology presents an educational resource for an emerging field | PLOS Biologue

Translational Bioinformatics: PLOS Computational Biology presents an educational resource for an emerging field | PLOS Biologue | Virology and Bioinformatics from Virology.ca | Scoop.it

PLOS Computational Biology is pleased to announce the launch of a new collection of Education articles:  “Translational Bioinformatics”. This collection is presented as an online “book” which could serve as a reference tool for a graduate level introductory course, marking a step in an exciting new direction for the Education section of the journal.

more...
No comment yet.
Rescooped by Chris Upton + helpers from Microbe
Scoop.it!

Drinking water unexpectedly rich in microbial life

Drinking water unexpectedly rich in microbial life | Virology and Bioinformatics from Virology.ca | Scoop.it
Flow cytometry can now be officially used for the quantification of microbial cells in drinking water. The new analytical method provides much more realistic results than the conventional method, in which bacterial colonies are grown on agar plates.

Via Ed Rybicki, Roberto Fernández Crespo
more...
Ed Rybicki's curator insight, January 27, 2013 12:19 PM

Pretty much mirrors phage practicals we used to do in MCB here at UCT: tap water was always cleaner in terms of coliphages than bottled mineral water.  I'd still go with phages over flow cytometry, though: it was exquisitely sensitive, and a LOT cheaper.

Scooped by Kenzibit
Scoop.it!

Genotypic and phenotypic diversity in the noncapsulated Haemophilus infl uenzae: adaptation and pathogenesis in the human airways | Garmendia | International Microbiology

Genotypic and phenotypic diversity in the noncapsulated Haemophilus infl uenzae: adaptation and pathogenesis in the human airways | Garmendia | International Microbiology | Virology and Bioinformatics from Virology.ca | Scoop.it
Genotypic and phenotypic diversity in the noncapsulated Haemophilus infl uenzae: adaptation and pathogenesis in the human airways
Kenzibit's insight:

The human respiratory tract contains a highly adapted microbiota including commensal and opportunistic pathogens. Noncapsulated or nontypable Haemophilus infl uenzae (NTHi) is a human-restricted member of the normal airway microbiota in healthy carriers and an opportunistic pathogen in immunocompromised individuals. The duality of NTHi as a colonizer and as a symptomatic infectious agent is closely related to its adaptation to the host, which in turn greatly relies on the genetic plasticity of the bacterium and is facilitated by its condition as a natural competent. The variable genotype of NTHi accounts for its heterogeneous gene expression and variable phenotype, leading to differential host-pathogen interplay among isolates. Here we review our current knowledge of NTHi diversity in terms of genotype, gene expression, antigenic variation, and the phenotypesassociated with colonization and pathogenesis. The potential benefi ts of NTHi diversity studies discussed herein include the unraveling of pathogenicity clues, the generation of tools to predict virulence from genomic data, and the exploitation of a unique natural system for the continuous monitoring of long-term bacterial evolution in human airways exposed to noxious agents. Finally, we highlight the challenge of monitoring both the pathogen and the host in longitudinal studies, and of applying comparative genomics to clarify the meaning of the vast NTHi genetic diversity and its translation to virulence phenotypes. [Int Microbiol 2012; 15(4): 157-170]

more...
No comment yet.
Scooped by Nicolas Palopoli
Scoop.it!

Different Regions of the HPV-E7 and Ad-E1A Viral Oncoproteins Bind Competitively but through Distinct Mechanisms to the CH1 Transactivation Domain of p300 - Biochemistry (ACS Publications)

Different Regions of the HPV-E7 and Ad-E1A Viral Oncoproteins Bind Competitively but through Distinct Mechanisms to the CH1 Transactivation Domain of p300 - Biochemistry (ACS Publications) | Virology and Bioinformatics from Virology.ca | Scoop.it
Nicolas Palopoli's insight:

Two oncoproteins with different structures and from different viruses use distinct mechanisms to bind the same partner and disrupt its function.

more...
No comment yet.
Scooped by Kenzibit
Scoop.it!

How cells' DNA repair machinery can destroy viruses

How cells' DNA repair machinery can destroy viruses | Virology and Bioinformatics from Virology.ca | Scoop.it
Researchers have decoded a system that makes certain types of immune cells impervious to HIV infection.
Kenzibit's insight:

A team of researchers based at Johns Hopkins has decoded a system that makes certain types of immune cells impervious to HIV infection. The system's two vital components are high levels of a molecule that becomes embedded in viral DNA like a code written in invisible ink, and an enzyme that, when it reads the code, switches from repairing the DNA to chopping it up into unusable pieces. The researchers, who report the find in the Jan. 21 early edition of the Proceedings of the National Academy of Sciences, say the discovery points toward a new approach to eradicating HIV from the body.

more...
No comment yet.
Scooped by Rebecca Kreston
Scoop.it!

Fears downpour may fuel dengue cases - ABC News (Australian Broadcasting Corporation)

Fears downpour may fuel dengue cases - ABC News (Australian Broadcasting Corporation) | Virology and Bioinformatics from Virology.ca | Scoop.it
Health experts say days of rain in Cairns, in far north Queensland, could lead to more people catching dengue fever.
more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

A survey of tools for variant analysis of next-generation genome sequencing data

more...
No comment yet.
Scooped by Kenzibit
Scoop.it!

Immune cells engineered in lab to resist HIV infection, study shows

Immune cells engineered in lab to resist HIV infection, study shows | Virology and Bioinformatics from Virology.ca | Scoop.it
Researchers have found a novel way to engineer key cells of the immune system so they remain resistant to infection with HIV, the virus that causes AIDS.
more...
No comment yet.
Scooped by Kenzibit
Scoop.it!

Poly(I:c)/alum mixed adjuvant priming enhances HBV ... [PLoS One. 2013] - PubMed - NCBI

PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

ZMap - Wellcome Trust Sanger Institute

ZMap - Wellcome Trust Sanger Institute | Virology and Bioinformatics from Virology.ca | Scoop.it

ZMap is a genome browser written in C with the aim of providing fast access to high volume data. Data may be requested from a variety of disparate sources in parallel and cached locally allowing new tracks to be loaded or the view of current data adjusted without delay. Multiple views of the data may be presented and tracks configured for different levels of detail. ZMap interfaces seamlessly to the Seqtools package and forms part of the Otterlace genome annotation system used by the HAVANA group at the Wellcome Trust Sanger Institute.

ZMap may also be used as a standalone browser taking data either from external soruces or from simple GFF files held locally.

more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

On Constructing Suffix Arrays and LCP Arrays in External Memory « Homologus

On Constructing Suffix Arrays and LCP Arrays in External Memory « Homologus | Virology and Bioinformatics from Virology.ca | Scoop.it
more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Biochemistry Free and Easy | Department of Biochemistry and Biophysics

Biochemistry Free and Easy | Department of Biochemistry and Biophysics | Virology and Bioinformatics from Virology.ca | Scoop.it

Kevin Ahern and Indira Rajagopal have published an electronic book aimed at helping students learn the basics of biochemistry in a fun and engaging format.  The book incorporates original songs, recordings, verses and links to over 100 video lectures.  

As its name implies, THE BOOK IS FREE.

Chris Upton + helpers's insight:

I looked at the iPad version.  It's very nicely laid out and content is super clear.

more...
No comment yet.
Scooped by Naomi Osborne
Scoop.it!

Cartilage in joints secretes antimicrobial factor

Cartilage in joints secretes antimicrobial factor | Virology and Bioinformatics from Virology.ca | Scoop.it
‘’It is clear that we might not ever see global warming, the apocalyptic scenario is that when I need a new hip in 20 years I’ll die from a routine infection because we’ve run out of antibiotics.’’ This statement was given by Dame Sally Davies...
more...
No comment yet.
Rescooped by Chris Upton + helpers from Bio-informatics
Scoop.it!

Re-searcher – System for Recurrent Searches of Homologs in Protein Sequence databases


Via Loiret David
more...
Loiret David's curator insight, January 26, 2013 4:08 PM

Re-searcher is a user-friendly configurable system for recurrent searches and reporting of new homologs in specified protein sequence databases. Searches can be performed at desired intervals either within NCBI or local databases using BLAST or PSI-BLAST. In addition to searches against an individual database, the system can perform “PDB-BLAST”-like combined searches, when PSI-BLAST profile generated during search against the first database is used to search the second database. The system supports multiple users each keeping track of multiple queries and query-specific results.

Scooped by Chris Upton + helpers
Scoop.it!

Virology Journal | Abstract | Analysis of whole genome sequences of 16 strains of rubella virus from the United States, 1961--2009

Rubella virus is the causative agent of rubella, a mild rash illness, and a potent teratogenic agent when contracted by a pregnant woman. Global rubella control programs target the reduction and elimination of congenital rubella syndrome.
more...
No comment yet.
Scooped by Kenzibit
Scoop.it!

Association of human papillomavirus type 16 long control region mutation and cervical cancer

The variation of human papillomavirus (HPV) genes or HPV variants demonstrates different risks of cervical cancer.
more...
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Characterization of HIV-1 gag and nef in Cameroon: further evidence of extreme diversity at the origin of the HIV-1 group M epidemic

Cameroon, in west central Africa, has an extraordinary degree of HIV diversity, presenting a major challenge for the development of an effective HIV vaccine.
Ed Rybicki's insight:

...and it's partially from Cape Town, making it doubly interesting.

more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Research into Contagious Bird Flu Starts After Moratorium | Observations, Scientific American Blog Network

After public outcry against research into avian flu strains that can be transmitted among mammals, 40 of the top scientists working on the influenza strains signed ...
Chris Upton + helpers's insight:

They mean bird flu that's contagious for humans...  LOL

more...
No comment yet.
Scooped by burkesquires
Scoop.it!

H5N1 virus: Transmission studies resume for avian flu : Nature : Nature Publishing Group

H5N1 virus: Transmission studies resume for avian flu : Nature : Nature Publishing Group | Virology and Bioinformatics from Virology.ca | Scoop.it
more...
Chris Upton + helpers's comment, January 23, 2013 2:45 PM
Snap!
Scooped by Chris Upton + helpers
Scoop.it!

32nd Annual American Society for Virology July 20-24, 2013, Penn State University

more...
No comment yet.
Scooped by Kenzibit
Scoop.it!

The half-life of the HSV-1 1.5-kb LAT intron is... [J Neurovirol. 2013] - PubMed - NCBI

PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
more...
No comment yet.