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Virology and Bioinformatics from Virology.ca
Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure
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Scientists Identify Infection Strategy of Widespread Virus | www.ucsf.edu

Scientists Identify Infection Strategy of Widespread Virus | www.ucsf.edu | Virology and Bioinformatics from Virology.ca | Scoop.it
Kenzibit's insight:

Scientists at the Gladstone Institutes have mapped the molecular mechanism by which a virus known as cytomegalovirus (CMV) so successfully infects its hosts. This discovery paves the way for new research avenues aimed at fighting this and other seemingly benign viruses that can turn deadly.

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Geneious

Geneious is a DNA and Protein analysis, alignment and assembly software, that combines powerful bioinformatic and molecular biology tools into one easy to use package.
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Pathogenesis of measles virus infection | The WritePass Journal

Pathogenesis of measles virus infection | The WritePass Journal | Virology and Bioinformatics from Virology.ca | Scoop.it
(2010) Measles virus infection of alveolar marcrophages and dendritic cells precedes spread to lymphatic organs in transgenic mice expression human signaling lymphocytic activation molecules (SLAM, CD150).

Via Gilbert Faure au nom de l'ASSIM, Kenzibit
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100 Diagrams That Changed the World

100 Diagrams That Changed the World | Virology and Bioinformatics from Virology.ca | Scoop.it
A visual history of human sensemaking, from cave paintings to the world wide web.

Since the dawn of recorded history, we've been using vi
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Changes in subcellular localization reveal interactions between human cytomegalovirus terminase subunits

During herpesvirus replication, terminase packages viral DNA into capsids. The subunits of herpes simplex virus terminase, UL15, UL28, and UL33, assemble in the cytoplasm prior to nuclear import of the complex.
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Emerging Infections, Microbial Threats to Health, and the Microbiome - Institute of Medicine

This Anniversary Symposium will look back at look back at the drivers and leadership behind the 1992 (Emerging Infections) and 2003 (Microbial Threats to Health) reports; review and assess the progress made on these reports’ recommendations; and,...
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Altered of apoptotic markers of both extrinsic and intrinsic pathways induced by hepatitis C virus infection in peripheral blood mononuclear cells

Chronic hepatitis C (CHC) has emerged as a leading cause of cirrhosis in the U.S. and across the world.
Kenzibit's insight:

Chronic hepatitis C (CHC) has emerged as a leading cause of cirrhosis in the U.S. and across the world. To understand the role of apoptotic pathways in hepatitis C virus (HCV) infection, we studied the mRNA and protein expression patterns of apoptosis-related genes in peripheral blood mononuclear cells (PBMC) obtained from patients with HCV infection.

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MGAviewer: a desktop visualization tool for analysis of metagenomics alignment data

MGAviewer: a desktop visualization tool for analysis of metagenomics alignment data | Virology and Bioinformatics from Virology.ca | Scoop.it
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Nature : Know when your numbers are significant

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Chris Upton + helpers's comment, December 20, 2012 1:26 PM
This is a good article...
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Viruses hijack cellular microRNAs for their own advantage

Post by Andras Donaszi-Ivanov, University of East Anglia Researchers have found that respiratory syncytial virus (RSV) can manipulate levels of regulatory genetic material, called microRNAs, in hos...
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PLOS ONE: The Fast Changing Landscape of Sequencing Technologies and Their Impact on Microbial Genome Assemblies and Annotation

PLOS ONE: The Fast Changing Landscape of Sequencing Technologies and Their Impact on Microbial Genome Assemblies and Annotation | Virology and Bioinformatics from Virology.ca | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
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Virus rebuilds heart's own pacemaker

Virus rebuilds heart's own pacemaker | Virology and Bioinformatics from Virology.ca | Scoop.it
A pacemaker has been built inside a heart by converting beating muscle into cells which can control the organ's rhythm, US researchers report.
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Morbillivirus-host interaction: lessons from aquatic mammals

Morbillivirus-host interaction: lessons from aquatic mammals | Virology and Bioinformatics from Virology.ca | Scoop.it

In the last 25 years, no less than 10 dramatic morbilliviral epidemics have occurred among free-ranging pinniped and cetacean species and populations worldwide. The origin(s) of the new Morbillivirus genus members causing these mass mortality events, along with the reason(s) behind their “sudden” appearance among wild aquatic mammals, are totally unknown (Di Guardo et al., 2005, 2011b).

 
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TWiV 212: Apocalypse TWiV 122112 212

TWiV 212: Apocalypse TWiV 122112 212 | Virology and Bioinformatics from Virology.ca | Scoop.it
The TWiVerers answer listener email about GM chickens, a hendra vaccine for horses, online education, curing color blindness, Roosevelt and polio, and more.
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BioinfoProject About: Evolutionary Biology 101

Chris Upton + helpers's insight:

All sorts of good stuff here

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Toward a three-dimensional view of protein networks between species | Frontiers in Virology

Toward a three-dimensional view of protein networks between species | Frontiers in Virology | Virology and Bioinformatics from Virology.ca | Scoop.it
burkesquires's insight:

"General principles governing biomolecular interactions between species are expected to differ significantly from known principles governing the interactions within species, yet these principles remain poorly understood at the systems level. A key reason for this knowledge gap is the lack of a detailed three-dimensional (3D), atomistic view of biomolecular interaction networks between species. Recent progress in structural biology, systems biology, and computational biology has enabled accurate and large-scale construction of 3D structural models of nodes and edges for protein–protein interaction networks within and between species. The resulting within- and between-species structural interaction networks have provided new biophysical, functional, and evolutionary insights into species interactions and infectious disease. Here, we review the nascent field of between-species structural systems biology, focusing on interactions between host and pathogens such as viruses."

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Trojan horse 'eliminates' cancer

Trojan horse 'eliminates' cancer | Virology and Bioinformatics from Virology.ca | Scoop.it
An experimental 'Trojan-horse' cancer therapy has completely eliminated prostate cancer in experiments on mice, according to UK researchers.
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STAR: ultrafast universal RNA-seq aligner

STAR: ultrafast universal RNA-seq aligner | Virology and Bioinformatics from Virology.ca | Scoop.it
Chris Upton + helpers's insight:

80 billion reads..... ???

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Twin attack could deliver universal flu vaccine - health - 19 December 2012 - New Scientist

Twin attack could deliver universal flu vaccine - health - 19 December 2012 - New Scientist | Virology and Bioinformatics from Virology.ca | Scoop.it
Combining two approaches to preventing flu might create lasting immunity against novel types
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HIV drug may be effective against MRSA

HIV drug may be effective against MRSA | Virology and Bioinformatics from Virology.ca | Scoop.it

Researchers have found that a current HIV drug called maraviroc could be a potential therapy for Staphylococcus aureus, a pathogen linked to hundreds of thousands of hospitalizations each year as well as being a common hospital ‘superbug’.


Via Dr. Stefan Gruenwald
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Chlamydia pneumoniae: modern insights into an ancient pathogen

Chlamydia pneumoniae: modern insights into an ancient pathogen | Virology and Bioinformatics from Virology.ca | Scoop.it
This short review examine the characteristic aspects of C. pneumoniae biology and offers insights into the diversity and evolution of this ancient pathogen.
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Scientists discover how HIV virus gains access to carrier immune cells to spread infection

Scientists have identified how HIV, the virus that causes AIDS, enters the cells of the immune system enabling it to be dispersed throughout an organism.
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PLOS Computational Biology: The Roots of Bioinformatics in ISMB

PLOS Computational Biology: The Roots of Bioinformatics in ISMB | Virology and Bioinformatics from Virology.ca | Scoop.it
PLOS Computational Biology is an open-access
Nicolas Palopoli's insight:

Besides the interesting recall of the Intelligent Systems for Molecular Biology (ISMB) annual conferences on computational biology, it offers a nice insight into current state-of-the-art methodologies and upcoming trends in the discipline.

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