Virology and Bioinformatics from Virology.ca
80.7K views | +8 today
Follow
 
Virology and Bioinformatics from Virology.ca
Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure
Your new post is loading...
Your new post is loading...
Scooped by Chris Upton + helpers
Scoop.it!

It's a group effort - the curators:

It's a group effort - the curators: | Virology and Bioinformatics from Virology.ca | Scoop.it

get in touch if you want to help curate this topic

more...
Bemol Sido's comment, October 10, 2015 5:28 AM
Thanks. Nice.
Bwana Moses's comment, May 25, 6:13 AM
Great work. Keep it going.
Rescooped by Kenzibit from Host Cell & Pathogen Interactions
Scoop.it!

Tiny Wire Can Detect A Single Virus In Your Urine

Tiny Wire Can Detect A Single Virus In Your Urine | Virology and Bioinformatics from Virology.ca | Scoop.it
Testing technique could make a versatile new diagnostic tool

Via Ed Rybicki, Kenzibit
more...
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Determinants of Arbovirus Vertical Transmission in Mosquitoes

Determinants of Arbovirus Vertical Transmission in Mosquitoes | Virology and Bioinformatics from Virology.ca | Scoop.it
Vertical transmission (VT) and horizontal transmission (HT) of pathogens refer to parental and non-parental chains of host-to-host transmission.
more...
No comment yet.
Scooped by Kenzibit
Scoop.it!

Sweet Honey Is Bacteria's Worst Nightmare

Sweet Honey Is Bacteria's Worst Nightmare | Virology and Bioinformatics from Virology.ca | Scoop.it
Honey contains multiple defense systems for fighting off bacteria, making it a natural and powerful antibacterial agent.
more...
No comment yet.
Scooped by Cindy
Scoop.it!

Omics! Omics!: Around the World in Amino Acids

This post is pure whimsy, growing out of killing time on a train ride. The not-so-serious question: what is the geography of amino acids?  If I search for them by name in Google Maps, what will I find?  With just Google Maps, plus some Google Translate thrown in, I found a few surprises.

Alanine
Marche Alanine, Goma, Congo
This was the first search and perhaps the most striking surprise -- why is there a market deep in Africa named Alanine?  
more...
No comment yet.
Scooped by Cindy
Scoop.it!

Both CD8+ and CD4+ T-Cells Contribute to Corneal Clouding and Viral Clearance Following Vaccinia Virus Infection in C57BL/6 Mice

Potentially blinding eye infections can occur after vaccination for Smallpox. Very little is known about the pathologic mechanisms that are involved and the information that is available was generated using rabbit models. The lack of immunological reagents for rabbits makes such studies difficult. We have characterized a mouse model of vaccinia virus ocular disease using C57BL/6 mice and strain WR and show that both CD4+ and CD8+ T-cell subsets play a role in the blinding eye disease and controlling virus replication. Based on these results vaccinia virus keratitis is significantly different from Herpes simplex virus keratitis and further studies using this model should generate novel insights into immunopathological responses to viral ocular infection.
more...
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

The Zombie Literature

The Zombie Literature | Virology and Bioinformatics from Virology.ca | Scoop.it
its authors maintain the voracity and robustness of its findings
Ed Rybicki's insight:
As they should, for a zombie lit paper B-)
more...
No comment yet.
Scooped by Kenzibit
Scoop.it!

Can Zika Be Misdiagnosed? The Virus Shares Similar Markers With Dengue Fever

Can Zika Be Misdiagnosed? The Virus Shares Similar Markers With Dengue Fever | Virology and Bioinformatics from Virology.ca | Scoop.it
The Zika virus has rapidly spreading throughout South America and the Caribbean over the past year, and recently it’s slowly been making its way into the
more...
No comment yet.
Rescooped by Chris Upton + helpers from Virology News
Scoop.it!

Caliciviruses in Australian rabbits: deliberate and accidental

Caliciviruses in Australian rabbits: deliberate and accidental | Virology and Bioinformatics from Virology.ca | Scoop.it

Via Ed Rybicki
more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Message to naturopaths: Magic isn’t medicine

Message to naturopaths: Magic isn’t medicine | Virology and Bioinformatics from Virology.ca | Scoop.it
A close look at naturopathy reveals a metaphysical belief system, although it is often expressed in the language of modern science
more...
No comment yet.
Rescooped by Kenzibit from Host Cell & Pathogen Interactions
Scoop.it!

Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation: Cell

Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation: Cell | Virology and Bioinformatics from Virology.ca | Scoop.it
more...
No comment yet.
Rescooped by Kenzibit from Emerging Viruses, Virus Discovery and Virus Characterization
Scoop.it!

Will Zika virus cast a shadow over the Rio Olympics?

Will Zika virus cast a shadow over the Rio Olympics? | Virology and Bioinformatics from Virology.ca | Scoop.it
travellers will be returning well before our peak periods of mosquito activity in central and north Queensland where those mosquitoes are present. Notwithstanding the preparedness of local authorities

Via Ian M Mackay, PhD
more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Targeted virus detection in next-generation sequencing data using an automated e-probe based approach

Targeted virus detection in next-generation sequencing data using an automated e-probe based approach | Virology and Bioinformatics from Virology.ca | Scoop.it
more...
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Structure of the T4 baseplate and its function in triggering sheath contraction

Structure of the T4 baseplate and its function in triggering sheath contraction | Virology and Bioinformatics from Virology.ca | Scoop.it
Several systems, including contractile tail bacteriophages, the type VI secretion system and R-type pyocins, use a multiprotein tubular apparatus to attach to and penetrate host cell membranes. This macromolecular machine resembles a stretched, coiled spring (or sheath) wound around a rigid tube with a spike-shaped protein at its tip. A baseplate structure, which is arguably the most complex part of this assembly, relays the contraction signal to the sheath. Here we present the atomic structure of the approximately 6-megadalton bacteriophage T4 baseplate in its pre- and post-host attachment states and explain the events that lead to sheath contraction in atomic detail. We establish the identity and function of a minimal set of components that is conserved in all contractile injection systems and show that the triggering mechanism is universally conserved.
Ed Rybicki's insight:
REALLY cool stuff: I've been fascinated by the "nanosyringe" character of phages with contractile tails since I was an undergraduate - and now 42 years later, we're seeing how those mechanisms actually work!
more...
No comment yet.
Rescooped by Kenzibit from Host Cell & Pathogen Interactions
Scoop.it!

Why humans (and not mice) are susceptible to Zika - Scienmag

Why humans (and not mice) are susceptible to Zika - Scienmag | Virology and Bioinformatics from Virology.ca | Scoop.it
Flaviviruses--such as Zika, dengue, and yellow fever--have emerged as human (and other primate) pathogens because of their ability to specifically overcome our anti-viral defenses. In the case of Zika..
more...
Gilbert C FAURE's curator insight, May 20, 1:45 AM
zika anf IFNs!
... one of the virus's seven non-structural proteins (NS5) is singularly responsible for blocking the action of interferons (proteins that stop viral replication) in human cells, while mouse cells are unaffected.
Rescooped by Kenzibit from Host Cell & Pathogen Interactions
Scoop.it!

Newly discovered microbe does something textbooks say is impossible: it lives without mitochondria

Newly discovered microbe does something textbooks say is impossible: it lives without mitochondria | Virology and Bioinformatics from Virology.ca | Scoop.it
Cells have adapted to find new ways of life.
more...
No comment yet.
Scooped by Cindy
Scoop.it!

Evaluation of hybrid and non-hybrid methods for de novo assembly of nanopore reads. - PubMed - NCBI

AVAILABILITY:
https://github.com/kkrizanovic/NanoMark CONTACT: mile.sikic@fer.hr SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
more...
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Becoming Acculturated: culturing the dark matter of microbiomes

Becoming Acculturated: culturing the dark matter of microbiomes | Virology and Bioinformatics from Virology.ca | Scoop.it
Techniques for deep dives into the microbial dark matter
more...
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Viral quasispecies complexity measures

Mutant spectrum dynamics (changes in the related mutants that compose viral populations) has a decisive impact on virus behavior. The several platforms of next generation sequencing (NGS) to study viral quasispecies offer a magnifying glass to study viral quasispecies complexity. Several parameters are available to quantify the complexity of mutant spectra, but they have limitations. Here we critically evaluate the information provided by several population diversity indices, and we propose the introduction of some new ones used in ecology. In particular we make a distinction between incidence, abundance and function measures of viral quasispecies composition. We suggest a multidimensional approach (complementary information contributed by adequately chosen indices), propose some guidelines, and illustrate the use of indices with a simple example. We apply the indices to three clinical samples of hepatitis C virus that display different population heterogeneity. Areas of virus biology in which population complexity plays a role are discussed.
more...
No comment yet.
Rescooped by Chris Upton + helpers from Virology News
Scoop.it!

Deadly fish virus finally identified

Deadly fish virus finally identified | Virology and Bioinformatics from Virology.ca | Scoop.it
Scientists believe the mysterious ‘tilapia lake virus’ behind mass die offs of farmed fish is a novel variety.

Via Ed Rybicki
more...
Ed Rybicki's curator insight, May 5, 7:22 AM
A virus which does not share most of its multisegment genome with anything else yet discovered: there's new viruses in them thar waters...!
Rescooped by Chris Upton + helpers from Virology News
Scoop.it!

Hand air-dryers are basically virus catapults

Hand air-dryers are basically virus catapults | Virology and Bioinformatics from Virology.ca | Scoop.it
Jet-drying technology spreads infectious agents much further than paper towels.

Via Ed Rybicki
Chris Upton + helpers's insight:
a
a case of being "too good", huh?
 
more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Rare disease genomics | Genomics England

Rare disease genomics | Genomics England | Virology and Bioinformatics from Virology.ca | Scoop.it
Rare disease genomics A rare disease is defined as one that affects less than 1 in 2,000 of the general population. There are between 5,000 and 8,000 known
more...
No comment yet.