Virology and Bioinformatics from Virology.ca
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Virology and Bioinformatics from Virology.ca
Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure
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A RIBOSOME-BINDING, 3’ TRANSLATIONAL ENHANCER HAS A T-SHAPED STRUCTURE AND ENGAGES IN A LONG DISTANCE RNA:RNA INTERACTION

A RIBOSOME-BINDING, 3’ TRANSLATIONAL ENHANCER HAS A T-SHAPED STRUCTURE AND ENGAGES IN A LONG DISTANCE RNA:RNA INTERACTION | Virology and Bioinformatics from Virology.ca | Scoop.it

Many plant RNA viruses contain elements in their 3’ UTRs that enhance translation. The PTE (Panicum mosaic virus-like translational enhancer) of Pea enation mosaic virus (PEMV) binds to eIF4E, but how this affects translation from the 5’ end is unknown. We have discovered a three-way branched element just upstream of the PEMV PTE that engages in a long-distance kissing-loop interaction with a coding sequence hairpin that is critical for translation of a reporter construct and accumulation of the viral genome in vivo.

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New Layer of Genetic Information Discovered

New Layer of Genetic Information Discovered | Virology and Bioinformatics from Virology.ca | Scoop.it

A hidden and never before recognized layer of information in the genetic code has been uncovered by a team of scientists at the University of California, San Francisco (UCSF) thanks to a technique developed at UCSF called ribosome profiling, which enables the measurement of gene activity inside living cells — including the speed with which proteins are made.


Via Dr. Stefan Gruenwald
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Sophia Smithe's comment, April 2, 2012 10:53 PM
It means genetic clock that is used widely should be changed as often the redundant bases are counted as not selectec.