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Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure
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Implications of finding poliovirus in sewers of Brazil and Israel

Implications of finding poliovirus in sewers of Brazil and Israel | Virology and Bioinformatics from Virology.ca | Scoop.it
Why has wild poliovirus been detected in the sewers of Brazil and Israel, and what are the implications for the eradication effort?

Via Ed Rybicki
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Ed Rybicki's curator insight, July 2, 5:12 AM

Not unexpectedly, a calm and thorough analysis of the potential problem from the "virology blog"!

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Polio Eradication: The Bad News Continues | Wired Science | Wired.com

Polio Eradication: The Bad News Continues | Wired Science | Wired.com | Virology and Bioinformatics from Virology.ca | Scoop.it
When last we left the long asymptote of polio eradication, nine health workers in Pakistan who had been administering polio vaccine had been murdered,
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Intracellular Vesicle Acidification Promotes Maturation of Infectious Poliovirus Particles

Intracellular Vesicle Acidification Promotes Maturation of Infectious Poliovirus Particles | Virology and Bioinformatics from Virology.ca | Scoop.it
The autophagic pathway acts as part of the immune response against a variety of pathogens. However, several pathogens subvert autophagic signaling to promote their own replication. In many cases it has been demonstrated that these pathogens inhibit or delay the degradative aspect of autophagy.
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Polio Outbreak in China

Cases of polio have been reported in China, the country’s first cases in more than 10 years :-(


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World Polio Day

World Polio Day | Virology and Bioinformatics from Virology.ca | Scoop.it
As a virologist who has worked on poliovirus since 1979, I would be remiss if I did not note that today, 24 October, is World Polio Day.

The polio eradication effort has made impressive progress towards eliminating polio from the planet. In 1988 it was estimated that there were a total of 350,000 cases of poliomyelitis (probably an underestimate); as of this writing there have been 301 cases in 2013, which is unfortunately already more than in all of 2012 (223). Some setbacks to the program include an outbreak in the Horn of Africa, the finding of wild poliovirus (but no paralytic cases) in Israel, and two suspected cases in Syria. Transmission of wild poliovirus has never been interrupted in three countries: Afghanistan, Nigeria, and Pakistan. The good news is that India remains polio-free, a remarkable achievement.

 


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Ed Rybicki's curator insight, October 25, 2013 2:55 AM

Thanks, Vincent!

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A Polio Outbreak In Pakistan Reveals Gaps In Vaccination : NPR

A Polio Outbreak In Pakistan Reveals Gaps In Vaccination : NPR | Virology and Bioinformatics from Virology.ca | Scoop.it

Pakistan has made a lot of progress this year in wiping out polio. There are signs that one type of poliovirus is gone and transmission of other strains seems to be slowing.

 

But a recent outbreak of polio there has health officials concerned about the overall effectiveness of the effort to eliminate polio in that country. The World Health Organization says 10 cases of so-called vaccine-derived polio were reported in Pakistan between the end of August and the end of October.

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Griffin Safety's curator insight, May 6, 12:42 AM

Sky News reports an increase in polio in Pakistan, Afghanistan and Nigeria.

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Why polio just became a global health crisis | Vaccinews Blog

Though only 650 cases were recorded last year, the World Health Organization declared the disease an emergency, but its importance goes beyond public health.
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