Virology and Bioi...
Follow
Find tag "measles"
51.0K views | +58 today
Virology and Bioinformatics from Virology.ca
Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure
Your new post is loading...
Your new post is loading...
Scooped by Hannah Davis
Scoop.it!

Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy - Mayo Clinic Proceedings

Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy - Mayo Clinic Proceedings | Virology and Bioinformatics from Virology.ca | Scoop.it

"MV-NIS is an engineered measles virus that is selectively destructive to myeloma plasma cells and can be monitored by noninvasive radioiodine imaging of NIS gene expression. Two measles-seronegative patients with relapsing drug-refractory myeloma and multiple glucose-avid plasmacytomas were treated by intravenous infusion of 1011 TCID50(50% tissue culture infectious dose) infectious units of MV-NIS. Both patients responded to therapy with M protein reduction and resolution of bone marrow plasmacytosis. Further, one patient experienced durable complete remission at all disease sites. Tumor targeting was clearly documented by NIS-mediated radioiodine uptake in virus-infected plasmacytomas. Toxicities resolved within the first week after therapy. Oncolytic viruses offer a promising new modality for the targeted infection and destruction of disseminated cancer."

more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Measles in BC: Then and Now

Measles in BC: Then and Now | Virology and Bioinformatics from Virology.ca | Scoop.it
Click image to enlarge
more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Measles is back. It had help - The Globe and Mail

Measles is back. It had help - The Globe and Mail | Virology and Bioinformatics from Virology.ca | Scoop.it
more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

MSF Responds To Increase In Measles in Southwestern Pakistan | Doctors Without Borders

MSF Responds To Increase In Measles in Southwestern Pakistan | Doctors Without Borders | Virology and Bioinformatics from Virology.ca | Scoop.it
Cases of measles are on the increase in the eastern region of Pakistan’s Balochistan Province.
more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

The Last Measle Fundraiser Video

The Last Measle - a short , animated video explaining the measles from a child's perspective

more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Current Opinion in Virology - Rinderpest eradication: lessons for measles eradication?

Current Opinion in Virology - Rinderpest eradication: lessons for measles eradication? | Virology and Bioinformatics from Virology.ca | Scoop.it

In 2011 the Food and Agriculture Organization formally announced that rinderpest was eradicated from the globe. Rinderpest virus had long been associated with huge disease outbreaks among cattle.

more...
No comment yet.
Scooped by Hannah Davis
Scoop.it!

Taming Measles Virus to Create an Effective Cancer Therapeutic - Mayo Clinic Proceedings

Taming Measles Virus to Create an Effective Cancer Therapeutic - Mayo Clinic Proceedings | Virology and Bioinformatics from Virology.ca | Scoop.it

"Measles virus (MV) has been a longtime bane of the human race. Once described by Rhazes (10th century Persian physician) as “more dreaded than smallpox,” it remains globally one of the leading causes of death among young children. In the 5 years before the introduction of the 1963 measles vaccination program, there were over 4 million cases of measles reported in the United States, and nearly twice as many deaths were attributed to measles as to polio infections during that same period. Yet for all the misery MV has caused and continues to inflict on mankind, it now appears that a genetically engineered version of the virus may be on its way to becoming an effective treatment for another deadly human malady, late-stage incurable myeloma."

more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Measles outbreak declared in Calgary, Edmonton and central Alberta

Measles outbreak declared in Calgary, Edmonton and central Alberta | Virology and Bioinformatics from Virology.ca | Scoop.it
Alberta officially declared a measles outbreak in Calgary, Edmonton and central Alberta on Tuesday.
more...
Ed Rybicki's comment, May 1, 8:24 AM
Fucking Luddites...
Scooped by Ed Rybicki
Scoop.it!

Rising measles outbreaks threaten vaccine-averse

Rising measles outbreaks threaten vaccine-averse | Virology and Bioinformatics from Virology.ca | Scoop.it

Seven confirmed cases of measles in Toronto, Ontario, so far this year, for a total of 12 in Canada to date, are prompting public health officials to remind doctors that the once-common childhood illness risks establishing a foothold again.

more...
Ed Rybicki's curator insight, May 6, 2013 4:23 PM

And why?  Because risk-averse parents aren't vaccinating their children against the things THEY were vaccinated against, which means we're back in the 1950s again as far as morbidity / mortality figures are concerned.

 

Scooped by Chris Upton + helpers
Scoop.it!

Virology Journal | Identification of different lineages of #measles virus strains circulating in Uttar Pradesh, North India

Genetic analysis of measles viruses associated with recent cases and outbreaks has proven to bridge information gaps in routine outbreak investigations and has made a substantial contribution to measles control efforts by helping to identify the...
more...
No comment yet.
Scooped by Ed Rybicki
Scoop.it!

Measles — United States, 2011 MMWR

Measles — United States, 2011 MMWR | Virology and Bioinformatics from Virology.ca | Scoop.it

"In 2000, the United States achieved measles elimination (defined as interruption of year-round endemic measles transmission) (1). However, importations of measles into the United States continue to occur, posing risks for measles outbreaks and sustained measles transmission. During 2011, a total of 222 measles cases (incidence rate: 0.7 per 1 million population) and 17 measles outbreaks (defined as three or more cases linked in time or place) were reported to CDC, compared with a median of 60 (range: 37–140) cases and four (range: 2–10) outbreaks reported annually during 2001–2010. This report updates an earlier report on measles in the United States during the first 5 months of 2011 (2). Of the 222 cases, 112 (50%) were associated with 17 outbreaks, and 200 (90%) were associated with importations from other countries, including 52 (26%) cases in U.S. residents returning from abroad and 20 (10%) cases in foreign visitors. Other cases associated with importations included 67 (34%) linked epidemiologically to importations, 39 (20%) with virologic evidence suggesting recent importation, and 22 (11%) linked to cases with virologic evidence of recent importation. Most patients (86%) were unvaccinated or had unknown vaccination status.

 

The increased numbers of outbreaks and measles importations into the United States underscore the ongoing risk for measles among unvaccinated persons and the importance of vaccination against measles (3)."

 

Amen!!  It is VERY revealing that so many cases were associated with imported virus infections - 90%!!  And almost HALF of those came from Europe, rather than from some developing country.

 

I thank Linda Stannard for the paramyxovirus EM

more...
No comment yet.
Scooped by Chris Upton + helpers
Scoop.it!

Measles Surge in Europe Raises Risks for Sports Fans

Measles Surge in Europe Raises Risks for Sports Fans | Virology and Bioinformatics from Virology.ca | Scoop.it

Sports fans at the London Olympics and European Championships for soccer later this year may face a
greater risk of contracting measles as vaccination rates drop across the continent, health authorities said.

more...
No comment yet.