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Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure
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The effect of enterovirus 71 immunization on neurop... [Virology. 2012] - PubMed - NCBI

Enterovirus 71 (EV71) is a major pathogen that causes hand-foot-mouth disease (HFMD). Our previous studies have demonstrated that the complete process of pathogenesis, which may include tissue damage induced by host inflammatory responses and direct tissue damage caused by viral infection, can be observed in the central nervous system (CNS) of animals infected in the laboratory with EV71. Based on these observations, the neuropathogenesis and protein expression profiles in the thalamic tissues of EV71-infected animals were further analyzed in the present study. Changes in protein expression profiles following immunization with the inactivated EV71 vaccine followed by virus challenge were observed and evaluated, and their physiological roles in viral pathogenesis are discussed. Taken together, the results of these experiments provide evidence regarding the neuropathogenesis and molecular mechanisms associated with EV71 infection and identify several protein indicators of pathogenic changes during viral infection.

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Archives of Virology, Characterization of a novel porcine enterovirus in wild boars in Hungary

Archives of Virology, Characterization of a novel porcine enterovirus in wild boars in Hungary | Virology and Bioinformatics from |

Porcine enteroviruses (PEVs) are members of the family Picornaviridae, genus Enterovirus. Until now, only three different PEV genotypes (PEV-9 and -10, and PEV-3H/PEV-14) have been detected in domestic pigs, and there is no information about the presence of PEVs in wild animals. H


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Enterovirus Found in Cambodia Outbreak

Enterovirus Found in Cambodia Outbreak | Virology and Bioinformatics from |

Health officials investigating an unexplained disease outbreak that has killed more than 50 children in Cambodia say they have detected the presence of a virus that causes hand, foot and mouth disease. The most severe cases are associated with dehydration, but this enteric virus also causes neurological symptoms.

Via Dr. Mary T. Johnson
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