Viruses and Bioinformatics from Virology.uvic.ca
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Viruses and Bioinformatics from Virology.uvic.ca
Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure
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Scooped by Ed Rybicki
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Adaptive Changes in Alphavirus mRNA Translation Allowed Colonization of Vertebrate Hosts

"Genetic, phylogenetic, and biochemical data presented here support an evolutionary scenario for the natural history of alphaviruses, in which the acquisition of DLP structure in their mRNAs probably allowed the colonization of vertebrate host and the consequent geographic expansion of some of these viruses worldwide."

 

I have taught for some time now that the evolution of many mammalian viruses must have involved adaptation of originally (and sometimes still) insect-infecting agents - given that insects crawled out onto dry land quite a long time before vertebrates did.  This is a nice illustration of that.  Pity I don't teach anymore B-(

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Genome-Scale Phylogeny of the Alphavirus Genus Suggests a Marine Origin

Using full-length sequences of all known alphaviruses, we produced a robust and comprehensive phylogeny of the Alphavirus genus, presenting a more complete evolutionary history of these viruses compared to previous studies based on partial sequences. Our phylogeny suggests the origin of the alphaviruses occurred in the southern oceans and spread equally through the Old and New World. Since lice appear to be involved in aquatic alphavirus transmission, it is possible that we are missing a louse-borne branch of the alphaviruses.

 

Of course, I think ALL viruses came out of the water - some longer ago than others.  Always thought that was a lousy branch of virology...thanks Stephen Korsman!


Via Ed Rybicki
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