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Virology and Bioinformatics from Virology.ca
Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure
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Respiratory syncytial virus (RSV): Potential significant opportunity for effective vaccine

Respiratory syncytial virus (RSV): Potential significant opportunity for effective vaccine | Virology and Bioinformatics from Virology.ca | Scoop.it
  Pioneering new research into respiratory syncytial virus (RSV) may have overcome the barriers that have impeded the development 

of an effective vaccine against the deadly virus.

RSV is a virus that causes lower respiratory tract infections and is a major cause of childhood morbidity and mortality worldwide. Attempts to develop vaccines against the virus in the 1960s were dogged with disastrous results, with the formalin-inactivated vaccine(FI-RSV) causing the RSV disease to actually worsen in many cases.

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Common virus can lead to life-threatening conditions in children

Respiratory Syncytial Virus (RSV) is a common virus that infects the lungs and breathing passage ways. Though it may only produce minor cold symptoms in adults, it can lead to serious illness in young children and those with compromised immune systems....

According to the Centers for Disease Control, RSV is the leading cause of bronchiolitis, an inflammation of the small airways in the lung, in infants under the age of 1. Most children will have been exposed to RSV by their second birthday.


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Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma : Nature Medicine : Nature Publishing Group

Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma : Nature Medicine : Nature Publishing Group | Virology and Bioinformatics from Virology.ca | Scoop.it
Recurrent infections with respiratory syncytial virus (RSV) early in life increase susceptibility to asthma. Nandini Krishnamoorthy et al. show that RSV infection of young mice impairs maternally transferred tolerance to allergens.
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Pathogenesis of respiratory syncytial virus 10.1016/j.coviro.2012.01.008 : Current Opinion in Virology | ScienceDirect.com

Pathogenesis of respiratory syncytial virus 10.1016/j.coviro.2012.01.008 : Current Opinion in Virology | ScienceDirect.com | Virology and Bioinformatics from Virology.ca | Scoop.it

While affecting all age groups, respiratory syncytial virus (RSV) infections can be particularly severe in infants, who develop functionally distinct immune responses, as well as in immunocompromised individuals.

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