Accurate measurement of biological vector titre is a key parameter for in vivo study and gene therapy. Here, the authors designed a qPCR system for the single-tube assessment of lentiviral vector copy numbers that is suitable for analyses in at least 33 different mammalian species, including human and other primates, mouse, pig, cat and domestic ruminants.
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Accurate measurement of biological vector titre is a key parameter for in vivo study and gene therapy. Here, the authors designed a qPCR system for the single-tube assessment of lentiviral vector copy numbers that is suitable for analyses in at least 33 different mammalian species, including human and other primates, mouse, pig, cat and domestic ruminants.
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