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On the Street: University of Victoria secures patent to help target tumours

On the Street: University of Victoria secures patent to help target tumours | Biomedical Beat | Scoop.it
A U.S. patent has been granted for a new process developed at the University of Victoria that will help oncologists better identify and target cancerous tumours. It involves synthesizing lanthanide. . .
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CBR: cbr.uvic.ca

CBR:  cbr.uvic.ca | Biomedical Beat | Scoop.it

The CBR is a multidisciplinary unit with an emphasis on genetics, molecular biology, and biotechnology. The centre was created to promote interdisciplinary basic and translational biomedical research. Our members span several UVic departments, the UVic Division of Medical Sciences, the Vancouver Island Health Authority and the BC Cancer Agency.

 

This topic will provide general info on a variety health and science related subjects, mirroring the interests of the CBR members.

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Anatomy of a Virus | The Scientist Magazine®

Anatomy of a Virus | The Scientist Magazine® | Biomedical Beat | Scoop.it
A mass spectrometry-based analysis of influenza virions provides a detailed view of their composition.
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Human genome was shaped by an evolutionary arms race with itself

Human genome was shaped by an evolutionary arms race with itself | Biomedical Beat | Scoop.it
An evolutionary arms race between rival elements within the genomes of primates drove the evolution of complex regulatory networks that orchestrate the activity of genes in every cell of our bodies, researach shows. The arms race is between mobile DNA sequences known as 'retrotransposons' (a.k.a. 'jumping genes') and the genes that have evolved to control them.
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Nobel Prize-winning ‘iPSC’ Stem Cell Method Vastly Improved

Nobel Prize-winning ‘iPSC’ Stem Cell Method Vastly Improved | Biomedical Beat | Scoop.it
By adding just three compounds to the Nobel Prize-winning induced pluripotent stem cell recipe, a research group is reporting a huge 90 to 100 percent stem cell haul in under a week.
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Intensive Loss of Gut Bacteria Diversity | The Scientist Magazine®

Intensive Loss of Gut Bacteria Diversity | The Scientist Magazine® | Biomedical Beat | Scoop.it
Lengthy stints in intensive care units pare down patients’ gut microflora, a study shows.
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Alcohol Sensations Influenced by Genes

Alcohol Sensations Influenced by Genes | Biomedical Beat | Scoop.it
How people perceive and taste alcohol depends on genetic factors, and that likely influences whether they "like" and consume alcoholic beverages, according to researchers.
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New Discovery About 3-D Shape Processing in the Brain

New Discovery About 3-D Shape Processing in the Brain | Biomedical Beat | Scoop.it
While previous studies of the brain suggest that processing of objects and place occur in very different locations, a research team has found that they are closely related.
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Newborns Have Stronger Immunity Than First Thought

Newborns Have Stronger Immunity Than First Thought | Biomedical Beat | Scoop.it
Contrary to what was previously thought, newborn immune T cells may have the ability to trigger an inflammatory response to bacteria, according to a new study.
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New Knowledge of Genes Driving Bladder Cancer Points to Targeted Treatments

New Knowledge of Genes Driving Bladder Cancer Points to Targeted Treatments | Biomedical Beat | Scoop.it
The story of cancer care seems so simple: find the mutated gene that causes cancer and turn it off or fix it. But rarely does a single gene cause cancer. More often, many genes are altered together to drive the disease. So the challenge becomes sorting out which altered genes are the most to blame in which cancers. A new study takes an important step toward answering this question in bladder cancer.
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Viruses spread easily from a single doorknob

Scientists have used special tracer viruses to show that contamination of just a single doorknob can leads to the spread of viruses throughout an entire office building. The idea was to see how easily something unpleasant like norovirus spreads.
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Ed Rybicki's curator insight, September 13, 4:50 AM

"Tracer viruses".  They put viruses on a doorknob??  Phages, obviously - and MS2 coliphage, to boot.  I would like to take a look at that ethics application...!

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ImmunizeCA App - Immunize Canada

ImmunizeCA App - Immunize Canada | Biomedical Beat | Scoop.it
The Canadian Public Health Association, Immunize Canada and the Ottawa Hospital Research Institute collaborated to develop an app for mobile devices that will help Canadians keep track of their vaccinations. The app is FREE and can be downloaded from iTunes, Google Play of BlackBerry World.
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Genetic Modifier Impacts Colon Tumor Formation

Genetic Modifier Impacts Colon Tumor Formation | Biomedical Beat | Scoop.it
Unexpected results from an ongoing experiment in the lab of Kristi Neufeld, Ph.D., co-leader of the Cancer Biology Program, led to a potentially important discovery that could have an impact on how cancer researchers test anti-cancer therapies in mice, and possibly prevent colon cancer in people.
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Evolution and Ecology of Influenza A Viruses.

Wild aquatic bird populations have long been considered the natural reservoir for influenza A viruses with virus transmission from these birds seeding other avian and mammalian hosts. While most evidence still supports this dogma, recent studies in bats have suggested other reservoir species may also exist. Extensive surveillance studies coupled with an enhanced awareness in response to H5N1 and pandemic 2009 H1N1 outbreaks is also revealing a growing list of animals susceptible to infection with influenza A viruses. Although in a relatively stable host-pathogen interaction in aquatic birds, antigenic, and genetic evolution of influenza A viruses often accompanies interspecies transmission as the virus adapts to a new host. The evolutionary changes in the new hosts result from a number of processes including mutation, reassortment, and recombination. Depending on host and virus these changes can be accompanied by disease outbreaks impacting wildlife, veterinary, and public health.

 
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Breaking News: Six Changing Faces of ‘Global Killer’ Bacteria

Breaking News: Six Changing Faces of ‘Global Killer’ Bacteria | Biomedical Beat | Scoop.it
Researchers have shown for the first time that a genetic switch allows Streptococcus pneumoniae to randomly change its characteristics into six alternative states.
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Muscle to Mind | The Scientist Magazine®

Muscle to Mind | The Scientist Magazine® | Biomedical Beat | Scoop.it
Exercise-induced muscle metabolites protect the brain from stress-induced depression in a mouse model. 
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Alzheimer's Patients Can Feel the Emotion After the Memories Have Vanished

Alzheimer's Patients Can Feel the Emotion After the Memories Have Vanished | Biomedical Beat | Scoop.it
A new study further supports an inescapable message: caregivers have a profound influence— good or bad— on the emotional state of individuals with Alzheimer’s disease.
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Cancer: The origin of human retinoblastoma : Nature : Nature Publishing Group

Cancer: The origin of human retinoblastoma : Nature : Nature Publishing Group | Biomedical Beat | Scoop.it
The cellular origins of most human cancers remain unknown, but an analysis of embryonic retinal cells identifies differentiating cones as the cell of origin for the childhood cancer retinoblastoma.
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Nanotubes Help Healing Hearts Keep the Beat

Nanotubes Help Healing Hearts Keep the Beat | Biomedical Beat | Scoop.it
Carbon nanotubes serve as bridges that allow electrical signals to pass unhindered through new pediatric heart-defect patches invented at Rice University and Texas Children’s Hospital.
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Tolerating, not fighting, viruses a viable survival strategy

Tolerating, not fighting, viruses a viable survival strategy | Biomedical Beat | Scoop.it
In ecology, disease tolerance is defined as a host strategy not to fight a pathogen tooth and nail, but rather tolerate it to live (and survive) better in the long term. One key feature of tolerance is that the disease only progresses very slowly -- if at all -- even if the host carries a high pathogen load. In some HIV sufferers, this approach is evident. A research team has now determined how strongly patients differ in their tolerance and upon which factors it depends.
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Sensing Neuronal Activity With Light

Sensing Neuronal Activity With Light | Biomedical Beat | Scoop.it
For years, neuroscientists have been trying to develop tools that would allow them to clearly view the brain's circuitry in action— from the first moment a neuron fires to the resulting behavior in a whole organism.
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Schizophrenia is Actually 8 Genetic Disorders

New research shows that schizophrenia isn’t a single disease but a group of eight genetically distinct disorders, each with its own set of symptoms.
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Expanding Our Understanding of Genomics - NIH Research Matters - National Institutes of Health (NIH)

Expanding Our Understanding of Genomics - NIH Research Matters - National Institutes of Health (NIH) | Biomedical Beat | Scoop.it
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Study Links Genetic Mutation to Melanoma Progression

Study Links Genetic Mutation to Melanoma Progression | Biomedical Beat | Scoop.it
Researchers have found that the genetic mutation BRAFV600E , frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumor cells, but can also modify the network of normal cells around the tumor to support the disease's progression.
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Team Finds Ovarian Cancer Oncogene in 'Junk DNA'

Team Finds Ovarian Cancer Oncogene in 'Junk DNA' | Biomedical Beat | Scoop.it
Over the years researchers have made tremendous strides in the understanding and treatment of cancer by searching genomes for links between genetic alterations and disease. Now, a team of researchers has mined "junk DNA" sequences to identify a non-protein-coding RNA whose expression is linked to ovarian cancer.
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CDC Media Statement on Newly Discovered Smallpox Samples

On July 1, 2014, the National Institutes of Health (NIH) notified the appropriate regulatory agency, the Division of Select Agents and Toxins (DSAT) of the Centers for Disease Control and Prevention (CDC), that employees discovered vials labeled ”variola,” commonly known as smallpox, in an unused portion of a storage room in a Food and Drug Administration (FDA) laboratory located on the NIH Bethesda campus.

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SimFlu: A simulation tool for predicting the variation pattern of influenza A virus.

SimFlu: A simulation tool for predicting the variation pattern of influenza A virus. | Biomedical Beat | Scoop.it

Since the first pandemic outbreak of avian influenza A virus (H5N1 subtype) in 1997, the National Center for Biotechnology Information (NCBI) has provided a large number of influenza virus sequences with well-organized annotations. Using the time-series sequences of influenza A viruses, we developed a simulation tool for influenza virus, named SimFlu, to predict possible future variants of influenza viruses. SimFlu can create variants from a seed nucleotide sequence of influenza A virus using the codon variation parameters included in the SimFlu package. The SimFlu library provides pre-calculated codon variation parameters for the H1N1, H3N2, and H5N1 subtypes of influenza A virus isolated from 2000 to 2011, allowing the users to simulate their own nucleotide sequences by selecting their preferred parameter options. SimFlu supports three operating systems - Windows, Linux, and Mac OS X. SimFlu is publicly available at http://lcbb.snu.ac.kr/simflu.

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