The CBR is a multidisciplinary unit with an emphasis on genetics, molecular biology, and biotechnology. The centre was created to promote interdisciplinary basic and translational biomedical research. Our members span several UVic departments, the UVic Division of Medical Sciences, the Vancouver Island Health Authority and the BC Cancer Agency.
This topic will provide general info on a variety health and science related subjects, mirroring the interests of the CBR members.
Many women with early-stage breast cancer can skip chemotherapy without hurting their odds of beating the disease - good news from a major study that shows the value of a gene-activity test to gauge each patient's risk.
Using an animal model they developed, Saint Louis University and Utah State university researchers have identified a strategy that could keep a common group of viruses called adenoviruses from replicating and causing sickness in humans.
The form of estrogens used in Hormone Therapy (HT) and previous motherhood are critical to explain why HT has variable effects on cognitive functions, new research suggests. In a recent study, estradiol had beneficial effects while estrone did not, researchers explain, adding that the effects of estrone also depended on the experience of motherhood.
A gene essential to the production of pain-sensing neurons in humans has been identified by an international team of researchers. The discovery, reported in the journal Nature Genetics, could have implications for the development of new methods of pain relief.
In the largest, most comprehensive genomic analysis of autism spectrum disorder (ASD) conducted to date, an international research team has identified 65 genes that play a role in the disorder, 28 of which are reported with “very high confidence,” meaning that there is 99 percent certainty that these genes contribute to the risk of developing ASD.
Prolonged sitting time as well as reduced physical activity contribute to the prevalence of non-alcoholic fatty liver disease (NAFLD) in a study of middle-aged Koreans. These findings support the importance of both reducing time spent sitting and increasing physical activity, say researchers.
A government task force says a daily low-dose aspirin could help certain people in their 50s and 60s prevent a first heart attack or stroke - and they might get some protection against colon cancer at the same time.
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One reason ovarian cancer is so deadly: it turns off immune cells that try to fight it. A Weill Cornell Medical College team has found that disarming a gene called XBP1 rearms immune cells—which successfully combat ovarian cancer.
Centre for Biomedical Research's insight:
Still being considered in the experimental stage but very exciting if it will work eventually!
Some brain tumor stem cells may have an Achilles’ heel, scientists have found. The cancer stem cells’ remarkable abilities have to be maintained, and researchers have identified a key player in that maintenance process. When the process is disrupted, they found, so is the spread of cancer.
Researchers have figured out how to create spheres of neuronal cells resembling the cerebral cortex, making functional human brain tissue available for the first time to study neuropsychiatric diseases such as autism and schizophrenia
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