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El 7% de los pacientes afectados por ELA en España presenta una mutación genética.

Un grupo de investigadores del Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas...
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Usal - MediNews
Noticias médico-sanitarias en la red
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Libro Blanco de la Nutrición en España

Libro Blanco de la Nutrición en España | Usal - MediNews | Scoop.it

 

 "El Libro Blanco es fruto de un convenio específico firmado entre la Agencia Española de Seguridad Alimentaria y Nutrición (AESAN) y la propia Fundación Española de la Nutrición (FEN), supone una "hoja de ruta" de la nutrición en sus numerosas facetas, todas de gran actualidad..."

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Libro Blanco de la Nutrición en España. Fundación Española de la Nutrición: Madrid: FEN. 2013

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New Stroke Technology: Stent and Pressure Activated Nanoparticles to Bust Clots

New Stroke Technology: Stent and Pressure Activated Nanoparticles to Bust Clots | Usal - MediNews | Scoop.it
Some ischemic strokes are now successfully treated using intravascular clot retrieval devices, but in many instances this option is not advised. Moreover,
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Early cancer diagnosis variation 'unacceptable'

Early cancer diagnosis variation 'unacceptable' | Usal - MediNews | Scoop.it
Vital opportunities to diagnose cancer patients in England earlier and increase their survival chances are being missed, experts are warning.
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Cuatro de cada 10 españoles mayores de 35 años presentan hipertensión arterial

Cuatro de cada 10 españoles mayores de 35 años presentan hipertensión arterial | Usal - MediNews | Scoop.it

"La Sociedad Española de Hipertensión-Liga Española para la Lucha contra la Hipertensión Arterial (SEH-LELHA) informa, con motivo del Día Nacional de la Hipertensión que se celebrará este sábado, de que en España más de un 40% de la población entre 35 y 64 años presenta hipertensión arterial y de que ese porcentaje supera el 65% entre los mayores de 65 años.

De hecho, la hipertensión arterial ocupa el primer puesto en la lista de problemas de salud en las consultas en Atención Primaria y es el primer factor de riesgo para el desarrollo de enfermedades cardiovasculares..."

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Childhood MMR vaccination rates fall - BBC News

Childhood MMR vaccination rates fall - BBC News | Usal - MediNews | Scoop.it
The proportion of two-year-old children having the MMR vaccine has fallen, according to NHS statistics.
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High Quality 3D Printed Model Hearts Printed Within Hours of MRI Scans

High Quality 3D Printed Model Hearts Printed Within Hours of MRI Scans | Usal - MediNews | Scoop.it

"At MIT and Boston Children's Hospital, researchers worked out a system allowing clinicians to take an MRI scan of patients' hearts and create 3D printed models of the organs within hour".

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Autistic and non-autistic brain differences isolated for first time

Autistic and non-autistic brain differences isolated for first time | Usal - MediNews | Scoop.it
The functional differences between autistic and non-autistic brains have been isolated for the first time, following the development of a new methodology for analysing…
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La secuenciación masiva revela al fin a la mayoría de hipoacusias hereditarias.DMedicina.com

La secuenciación masiva revela al fin a la mayoría de hipoacusias hereditarias.DMedicina.com | Usal - MediNews | Scoop.it
Paneles de diagnóstico genéticos desvelan un 60 por ciento de las sorderas poslocutivas. La investigación en terapia con células madre busca corregir las neuropatías auditivas.
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Activating genes on demand

Activating genes on demand | Usal - MediNews | Scoop.it

"When it comes to gene expression – the process by which our DNA provides the recipe used to direct the synthesis of proteins and other molecules that we need for development and survival – scientists have so far studied one single gene at a time. A new approach developed by Harvard geneticist George Church, Ph.D., can help uncover how tandem gene circuits dictate life processes, such as the healthy development of tissue or the triggering of a particular disease, and can also be used for directing precision stem cell differentiation for regenerative medicine and growing organ transplants".

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New Molecule Binds to Cancer's DNA, Prevents Replication

New Molecule Binds to Cancer's DNA, Prevents Replication | Usal - MediNews | Scoop.it
Researches at Bielefeld University in Germany have come upon a new method of disrupting the spread of cancer using molecules that bind to DNA. The team dev
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Kids with Autism, Sensory Processing Disorders Show Brain Wiring Differences

Kids with Autism, Sensory Processing Disorders Show Brain Wiring Differences | Usal - MediNews | Scoop.it
SOURCE May 14, 2015 Researchers at UC San Francisco have found that children with sensory processing disorders have decreased structural brain connections in specific sensory regions different than those in autism, further establishing SPD as a clinically important neurodevelopmental disorder. The research, published in the journal PLOS ONE, is the first study to compare structural connectivity in the brains of children with an autism diagnosis versus those with an SPD diagnosis, and with a group of typically developing boys. This new research follows UCSF’s groundbreaking study published in 2013 that was the first to find that boys affected with SPD have quantifiable regional differences in brain structure when compared to typically developing boys. This work showed a biological basis for the disease but prompted the question of how these differences compared with other neurodevelopmental disorders. Click on the graphic to view a larger version. “With more than 1 percent of
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Manipulating cells’ shapes could treat breast cancer

Manipulating cells’ shapes could treat breast cancer | Usal - MediNews | Scoop.it
Changing the shape of breast cancer cells could make the disease more sensitive to treatments - even driving the body's own inflammatory response against…
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INTERNATIONAL SKELETAL DYSPLASIA REGISTRY: ONLINE TEACHING ATLAS

INTERNATIONAL SKELETAL DYSPLASIA REGISTRY: ONLINE TEACHING ATLAS | Usal - MediNews | Scoop.it

El International Skeletal Dysplasia Registry - Online Teaching Atlas es un atlas en línea de referencia en Displasias Óseas elaborado por el Registro Internacional de Displasias Esqueléticas (International Skeletal Dysplasia Registry – ISDR). Se trata de un recurso educativo diseñado para ayudar a médicos e investigadores en el diagnóstico radiográfico de estos trastornos esqueléticos raros (osteocondrodisplasias)...

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New Cancer Cure uses Nanotechnology: AND cost could be cheap thanks to breakthrough with Algae

New Cancer Cure uses Nanotechnology: AND cost could be cheap thanks to breakthrough with  Algae | Usal - MediNews | Scoop.it
SOURCE November 10, 2015 Nanotechnology has long been considered among the best hopes for a cancer cure, but now perhaps the greatest hurdle to using nanotechnology — the science of creating microscopic machines the size of a single cell, molecule or even atom — to combat the feared and deadly disease may have been overcome. That obstacle, of course, is simply the cost of manufacturing the nanotechnology needed to infiltrate the human body to seek out and destroy individual cancer cells while leaving heathy cells and tissue unharmed. Not only would a cancer cure using artificially created nanoparticles cost so much that the medicine would likely be unavailable for widespread use, the process itself is also dangerous and environmentally destructive, requiring the use of deadly, industrial chemicals. The chemicals not only create toxic waste that can damage the environment, but can render the nanoparticles — that is, the microscopic machines — themselves toxic to humans. But a team led
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Oncolytic Maraba Virus Vaccine Technology | Turnstone Biologics

Oncolytic Maraba Virus Vaccine Technology | Turnstone Biologics | Usal - MediNews | Scoop.it

The Foundation – Maraba: The ideal oncolytic virus

The Maraba platform represents Turnstone’s lead oncolytic immunotherapy agent.  Maraba was bioselected from rhabdovirus isolates from around the world as the most potent tumour lytic strain. The final product was developed through iterative genetic engineering of Maraba to maximize its inherent safety and potency profile.  

Oncolytic Maraba Highlights:

Extremely potent at killing almost all types of human tumour cells testedHighly attenuated in normal healthy human cellsHumans have no pre-existing immune responses to impede its systemic deliveryCan be engineered to carry multi-transgene payloadsEasy to manufacture as a GMP biologic product

 

The Direct Cancer-Killing Properties of Turnstone’s Oncolytic Viral Immunotherapy Platform


Via Krishan Maggon
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Krishan Maggon 's curator insight, October 28, 2015 5:52 PM

FDA approval of Amgen oncolytic virus immunotherapy has put the  spotlight on another oncolytic immunotherapy start up,

 

Canadian TurnStone Biologics

 

Its lead product is in Phase I trials and the company plans to combine it with a checkpoint inhibitor (PD1/2 inhibitor)

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Un paso adelante para obtener células madre de sangre en laboratorio

Un paso adelante para obtener células madre de sangre en laboratorio | Usal - MediNews | Scoop.it

"Un equipo del Instituto Hospital del Mar de Investigaciones Médicas de Barcelona ha descubierto la forma de activar la proteína Notch para producir células madre hematopoyéticas en laboratorio. Según los autores, el hallazgo es importante en medicina regenerativa ya que permitirá en el futuro producir células aptas para trasplantes hematológicos a aquellos enfermos que no tengan donantes compatibles".

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Referencia bibliográfica:

Leonor Gama-Norton, Eva Ferrando, Cristina Ruiz-Herguido, Zenhy Liu, Jordi Guiu, Abul B.M.M.K. Islam, Sung-Uk Lee, Minhong Yan, Cynthia J. Guidos, Nuria López-Bigas, Takahiro Maeda, Lluis Espinosa, Raphael Kopan & Anna Bigas“Notch signal strength controls cell fate in the haemogenic endothelium”. Nature Communications. DOI: 10.1038/ncomms9510.

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Soutien gorge connecté pour le dépistage cancer du sein iTBra de la société Cyrcadia health

Soutien gorge connecté pour le dépistage cancer du sein iTBra de la société Cyrcadia health | Usal - MediNews | Scoop.it
Pour dépister les cancers du sein, la société Cyrcadia Health a développé un patch connecté, capable de déceler la présence d’une cellule cancéreuse.

Via FestivalCommunicationSanté, Rémy TESTON
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Bge Innovation's curator insight, September 27, 2015 4:32 PM

iTBra : système de détection thermique pour le dépistage du cancer du sein

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El antidepresivo Paxil no es seguro para los adolescentes, según un análisis reciente: MedlinePlus en español

El antidepresivo Paxil no es seguro para los adolescentes, según un análisis reciente: MedlinePlus en español | Usal - MediNews | Scoop.it
El antidepresivo Paxil no es seguro para los adolescentes, según un análisis reciente
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9 Ways Technology Helps Manage Alzheimer’s and Parkinson’s Disease

9 Ways Technology Helps Manage Alzheimer’s and Parkinson’s Disease | Usal - MediNews | Scoop.it
With all these technological advances, improvements and new devices coming to the market, we could significantly improve the lives of Parkinson’s and Alzheimer’s disease patients. They could change...
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Five research papers that revolutionised health

Five research papers that revolutionised health | Usal - MediNews | Scoop.it
Five pieces of scientific research that changed the face of medicine.
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Ayudas Fundación BBVA a Equipos de Investigación Científica (Convocatoria 2015)

Ayudas Fundación BBVA a Equipos de Investigación Científica (Convocatoria 2015) | Usal - MediNews | Scoop.it

"Las ayudas a proyectos de investigación objeto de esta convocatoria responden al compromiso de la Fundación BBVA con el impulso de la investigación científica y la creación cultural, y su proyección a la sociedad, como forma de ampliar las oportunidades individuales y colectivas".

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Multitasking hunger neurons also control compulsive behaviors

Multitasking hunger neurons also control compulsive behaviors | Usal - MediNews | Scoop.it
In the absence of food, neurons that normally control appetite initiate complex, repetitive behaviors seen in obsessive-compulsive disorder (OCD), and anorexia nervosa, according to…
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Identifican alteraciones en el sistema de recompensa cerebral de las personas con obesidad

Identifican alteraciones en el sistema de recompensa cerebral de las personas con obesidad | Usal - MediNews | Scoop.it

"Expertos españoles han descrito diferencias anatómicas en las estructuras cerebrales implicadas en el refuerzo de la conducta en un grupo de personas con obesidad. Este hallazgo puede servir para avanzar en la prevención y en la aplicación de tratamientos más individualizados o por subgrupos de pacientes".

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Referencia del artículo:

Marqués-Iturria, I.; Scholtens, L.H.; Garolera, M.; Pueyo, R.; García-García, I.; González-Tartiere, P.; Segura, B.; Junqué, C.; Sender-Palacios. M.J.; Vernet-Vernet, M.; Sánchez-Garre, C.; De Reus, M.A.; Jurado, M.A.; Van den Heuvel, M.P. «Affected connectivity organization of the reward system structure in obesity».Neuroimage, 111, 2015, p. 100-106. DOI: 10.1016/j.neuroimage.2015.02.012

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Novel drug mechanism that fights brain cancer

Novel drug mechanism that fights brain cancer | Usal - MediNews | Scoop.it
Researchers at UC Davis have developed and characterized a molecule that interferes with the internal regulation of cancer cells, causing them to self-destruct. This…
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Apagones en la corteza cerebral explican el comportamiento en red de las neuronas

Apagones en la corteza cerebral explican el comportamiento en red de las neuronas | Usal - MediNews | Scoop.it

Un nueva investigación analiza la actividad en red de las neuronas, es decir, cuando una neurona emite un impulso y las demás lo hacen. Los investigadores han descubierto la razón que hay detrás de este hecho: durante períodos breves de tiempo el cerebro silencia su actividad y las neuronas dejan de disparar impulsos a la vez...

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Autism appears 'largely genetic'

Autism appears 'largely genetic' | Usal - MediNews | Scoop.it
Autism is caused by genetic make-up in 74-98% of cases, a Medical Research Council study of 516 twins indicates.
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