Parkinson's & ALS Disease
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US clinical trial begun for treatment of Parkinson's Disease - Santa Clarita Valley Signal

US clinical trial begun for treatment of Parkinson's Disease - Santa Clarita Valley Signal | Parkinson's &  ALS Disease | Scoop.it
US clinical trial begun for treatment of Parkinson's Disease
Santa Clarita Valley Signal
Boston Scientific is conducting clinical trials in the United States for a system that improves motor function in people who have Parkinson's Disease.
Pacific Cove's insight:

“Medication works wonderfully in early Parkinson’s patients. But, beyond a certain point the body starts to develop a tolerance,” Nanavaty said. “There’s an ebb and flow that gets worse and worse because it’s a degenerative disease.

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Parkinson's &  ALS Disease
Parkinson's & ALS (Lou Gehrig) Disease Awareness  - Caregiving - Treatment - Bradykinesia
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Brain Surgery In Prime Time: National Geographic To Showcase Deep Brain Stimulation Procedure

Brain Surgery In Prime Time: National Geographic To Showcase Deep Brain Stimulation Procedure | Parkinson's &  ALS Disease | Scoop.it
National Geographic Channel will premiere a live, deep brain stimulation (DBS) neurosurgery on Sunday, Oct. 25.
Pacific Cove's insight:

First approved by the Food and Drug Administration in 1997, deep brain stimulation (DBS) was developed as a pioneering treatment for patients with essential tremor. Today it is performed to help patients with Parkinson’s disease as well. #Parkinson's  #Seniors #Caregivers #Caregiving 

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Incredible Medicine: Real-life superhero SMELLS Parkinson’s disease before it’s diagnosed

Incredible Medicine: Real-life superhero SMELLS Parkinson’s disease before it’s diagnosed | Parkinson's &  ALS Disease | Scoop.it
A SUPERHUMAN woman who can detect Parkinson’s disease using just her nose meets Dr Weston in the BBC Two programme Incredible Medicine.
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She identified all six of the Parkinson’s sufferers but said one of the non-Parkinson’s volunteers had the condition too. However, six months later that person was also diagnosed with the disease. #Parkinson'
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Longtime Dallas firefighter loses battle to ALS

Longtime Dallas firefighter loses battle to ALS | Parkinson's &  ALS Disease | Scoop.it
The Dallas Fire Department is mourning the loss of one of its best after a three-year battle with ALS.
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Tracy Beard was a 26-year veteran with the department. Station Four was the last place he worked but spent most of his career in South Dallas. And most of his free time was spent on the softball field, helping girls get to college.
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Andy's Journey: The Struggles Through ALS | Part II: An inescapable trap of a disease

Andy's Journey: The Struggles Through ALS | Part II: An inescapable trap of a disease | Parkinson's &  ALS Disease | Scoop.it
BRATTLEBORO — A cold day in February 2014. Snow on the ground outside, Andy Leclaire, of Brattleboro, waited inside an examination room at Cheshire Medical Center in Keene, N.H. His wife, Kathleen, was with him.Andy tapped his cane on the …
Pacific Cove's insight:
ALS is a progressive neurodegenerative disease, meaning it primarily affects the nervous systems in the brain and spinal cord. Eventually, a person loses use of their muscles. In time, people can't eat, speak or, ultimately, breathe. But their minds continue to work. #ALS
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Boxing For People With Parkinson’s Comes to Maine

Boxing For People With Parkinson’s Comes to Maine | Parkinson's &  ALS Disease | Scoop.it
Mid Coast Hospital news
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Share you"With Parkinson’s patients there is a range of difficulty with movement that affects voice, breathing, and general mobility. Through treatment, rehabilitation, exercise, and support, Mid Coast Hospital offers a full continuum of resources to help reduce symptoms and improve the lifestyles of PD patients.”  #Parkinson's
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Pesticide linked to Parkinson's disease being sold in US, already banned in Europe

Pesticide linked to Parkinson's disease being sold in US, already banned in Europe | Parkinson's &  ALS Disease | Scoop.it
Like other pesticides, paraquat has been the subject of controversy for some time now. In Switzerland, for example, the toxic substance has been banned since 1989. The rest of the European Union has followed the Swiss' lead, including England -- even though there is still a factory there where
Pacific Cove's insight:
Perhaps what is most disturbing about paraquat is that science has indicated that the pesticide was possibly linked to Parkinson’s disease for more than twenty years.
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Plaque-busting plants take on Alzheimer's and Parkinson's

Plaque-busting plants take on Alzheimer's and Parkinson's | Parkinson's &  ALS Disease | Scoop.it
​The fight against the debilitating effects of Alzheimer's and Parkinson's diseases may have just gotten a new weapon from an extract from the prickly pear cactus and brown seaweed known as peacock's tail – both which grow in abundance in the Mediterranean region.
Pacific Cove's insight:
The fight against the debilitating effects of Alzheimer's and Parkinson's diseases may have just gotten a new weapon from both a land-based and sea-based plant in the Mediterranean basin.
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Dogfish shark extract could help treat Parkinson’s disease, scientists hope 

Dogfish shark extract could help treat Parkinson’s disease, scientists hope  | Parkinson's &  ALS Disease | Scoop.it
A substance found in the livers of dogfish sharks could help treat Parkinson’s disease, scientists at Cambridge University believe.
Pacific Cove's insight:
The compound has already been used in clinical trials for cancer and eye conditions in America, and a trial in Parkinson's disease patients is now being planned by one of the researchers involved in the study.
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Parkinson's Disease symptoms, treatments & patient forums | PatientsLikeMe

Parkinson's Disease symptoms, treatments & patient forums | PatientsLikeMe | Parkinson's &  ALS Disease | Scoop.it
Parkinson's Disease: Find the most comprehensive real-world symptom and treatment data on Parkinson's at PatientsLikeMe. 10,273 patients with Parkinson's experience Slowness, Stiffness/Spasticity, Memory problems, Excessive daytime sleepiness (somnolence), and Insomnia and use Carbidopa-Levodopa, Rasagiline, Amantadine, Ropinirole, and Pramipexole to treat their Parkinson's and its symptoms.
Pacific Cove's insight:
What is Parkinson's Disease? Parkinson's Disease is a progressive disorder of the nervous system marked by muscle tremors, muscle rigidity, decreased mobility, stooped posture, slow voluntary movements, and a mask-like facial expression. #Parkinson's  #Tremors #Caregivers #Caregiving 
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On the Horizon: Virtual Reality Therapy That Treats Chronic Pain

On the Horizon: Virtual Reality Therapy That Treats Chronic Pain | Parkinson's &  ALS Disease | Scoop.it
Retraining the brain can restore mobility for people with injuries or difficulty moving
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Harvie believes that such therapy has the potential to restore full pain-free range of motion to people recovering from injuries and could perhaps help individuals with neurodegenerative diseases such as Parkinson's.  #Parkinson's #HealthCare #SeniorCare #Caregivers #Caregiving 

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FDA Approves Brain Stimulation Device for Parkinson's Disease

FDA Approves Brain Stimulation Device for Parkinson's Disease | Parkinson's &  ALS Disease | Scoop.it
Brio Neurostimulation System is second such device approved for tremor disorders
Pacific Cove's insight:

 Once activated, the device sends continuous electrical pulses to the target areas in the brain, blocking the impulses that cause tremors.  #Parkinson's #ALS #Tremors #Caregivers #Caregiving 

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New Compound Could Offer Therapy for Alzheimer’s, Parkinson’s

New Compound Could Offer Therapy for Alzheimer’s, Parkinson’s | Parkinson's &  ALS Disease | Scoop.it
An international research team has developed a compound that successfully targets and destroys aggregated proteins, leading to hopes for a new class of drugs effective against a multitude of diseases including Alzheimer’s and Parkinson’s.
Pacific Cove's insight:

The researchers call the compound ‘molecular tweezers’ because it wraps around particular amino acids in the protein, not the whole aggregate, and then it both prevents the formation of toxic aggregates and also breaks down preformed ones, in a slow process. #Alzheimers #Parkinsons #Dementia #Caregiving #Cargivers 

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Pacific Cove's curator insight, April 15, 2015 3:09 AM

The researchers call the compound ‘molecular tweezers’ because it wraps around particular amino acids in the protein, not the whole aggregate, and then it both prevents the formation of toxic aggregates and also breaks down preformed ones, in a slow process. #Alzheimers #Parkinsons #Dementia #Caregiving #Cargivers 

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14,000 Miles of Inspiration and Perspiration – Tour de Fox | Parkinson's Disease

14,000 Miles of Inspiration and Perspiration – Tour de Fox | Parkinson's Disease | Parkinson's &  ALS Disease | Scoop.it

His mom, Lucy, was diagnosed with Parkinson’s disease more than 15 years ago, and he dedicates his efforts to her. Yet he takes his greatest inspiration from the Parkinson’s community — the countless moms, dads and families touched by Parkinson’s, the second most common degenerative brain disease after Alzheimer’s, for which no cure has yet been found.

Pacific Cove's insight:

My mother is an inspiration to me, but it is not because she’s bravely fighting Parkinson’s — it’s because there was never any doubt that she would face and defeat whatever challenge arose...

I simply dedicate them to her for being my mom — one small part of all that she’s done, and all that she is.

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Medical Marijuana and Idiopathic Intracranial Hypertension

Medical Marijuana and Idiopathic Intracranial Hypertension | Parkinson's &  ALS Disease | Scoop.it
For many individuals with the neurological disorder idiopathic intracranial hypertension, a natural medicine with mild side effects is long overdue.
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As medical marijuana is slowly becoming accepted by mainstream medicine the world over, sufferers of idiopathic intracranial hypertension are taking notice and beginning to experiment with the herb.
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Nanci Ryder's Heartbreaking Battle: As ALS Robs Her of Eating and Driving, Power Publicist Still Curses Like a Sailor

Nanci Ryder's Heartbreaking Battle: As ALS Robs Her of Eating and Driving, Power Publicist Still Curses Like a Sailor | Parkinson's &  ALS Disease | Scoop.it
The Hollywood veteran, diagnosed with the progressive neurodegenerative disease in 2014, has given up everything from solid food to shopping and swears only by tapping on an iPad now, but she's still fighting (and fundraising for) ALS as her body fails. Says Bryan Lourd, "She won't let people look the other way."
Pacific Cove's insight:
Notoriously difficult to diagnose, ALS attacks motor neurons in the brain and spinal cord and can have different impacts on different people. For Ryder, 64, bulbar onset ALS meant the muscles that control chewing, swallowing and talking would be the first affected.
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A new brain mapping technique reveals circuitry of Parkinson’s disease tremors | Stanford News

A new brain mapping technique reveals circuitry of Parkinson’s disease tremors | Stanford News | Parkinson's &  ALS Disease | Scoop.it
The new technique probes the neural pathways that cause these tremors, and also provides a way to map and troubleshoot other circuits in the whole brain.
Pacific Cove's insight:
One hallmark of Parkinson’s disease are uncontrollable tremors. Neuroscientists believe that these tremors are caused by malfunctions in the neural pathways that control motion. They know that different regions of the brain are constantly forming circuits to carry out tasks, whether motion or speech. #Parkinsons 
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VA Leaves Corpse In Shower Room, VSOs Gush Over Sec McDonald?

VA Leaves Corpse In Shower Room, VSOs Gush Over Sec McDonald? | Parkinson's &  ALS Disease | Scoop.it
News that a veteran’s corpse was left in a shower room for nine hours linked to a cover-up as dinosaur VSOs call on Trump to keep Sec McDonald.
Pacific Cove's insight:
Adding insult to injury, VA was also caught in a failed cover-up at Bay Pines VA where agency health care workers were caught hiding a veteran’s corpse in the shower room to evade accountability. #Parkinson's 
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Former president's movement disorder mimics Parkinson's

Former president's movement disorder mimics Parkinson's | Parkinson's &  ALS Disease | Scoop.it
Former President George H.W. Bush, who has been placed in intensive care at a Houston hospital, is suffering from pneumonia and has vascular parkinsonism, a rare syndrome that mimics Parkinson's disease. The 92-year-old Bush also broke a vertebra in 2015 and has used a motorized scooter or a wheelchair in recent years. Some answers to common questions about his health: ___ Q: WHAT ARE THE RISKS OF PNEUMONIA? A: Pneumonia is an infection of the lungs that can be mild or severe. Elderly patients are at risk of deadly complications. The former president wrote to President-elect Donald Trump on Jan. 10, saying that he would be unable to attend Friday's inauguration because of doctor's orders: "My doctor says if I sit outside in January, it will likely put me six feet under. Same for Barbara. So I guess we're stuck in Texas." ___ Q: WHAT IS VASCULAR PARKINSONISM? A: People diagnosed with the condition walk with shuffling steps, and brain scans suggest they have suffered small strokes. However, they do not have the characteristic tremors of Parkinson's disease, and they do not respond to drugs for Parkinson's. "They look like Parkinson's from the waist down. From the waist up, they look very expressive," said Dr. Alberto Espay of the University of Cincinnati's Gardner Neuroscience Institute. ___ Q: IS IT DIFFERENT FROM PARKINSON'S DISEASE? A: Yes. It does not get steadily worse in the same way Parkinson's does. Classic Parkinson's disease develops when cells that produce one of the brain's chemical messengers, called dopamine, begin to deteriorate and die. Dopamine transports signals to parts of the brain that control movement. Parkinson's symptoms appear after enough dopamine-producing cells die that there's too little of this neurotransmitter in the brain. Vascular parkinsonism can closely mimic a number of other disorders, including classic Parkinson's, progressive supranuclear palsy and excessive fluid on the brain. ___ Q: WHAT HAS PRESIDENT BUSH SAID ABOUT THE CONDITION? A: In a 2012 interview with Parade magazine, Bush said: "It just affects the legs. It's not painful. You tell your legs to move, and they don't move. It's strange, but if you have to have some bad-sounding disease, this is a good one to get." Bush said the symptoms have been difficult for him, "because I love being active, (playing) sports, being in the game. . But you just face the reality and make the best of it." ___ Q: WHO GETS IT? A: People in their 70s and older are most likely be diagnosed, said Dr. Tanya Simuni who conducts research on Parkinson's and other movement disorders at Northwestern Medicine in Chicago. She calls it a "difficult diagnosis" because of the lack of accurate diagnostic tests. The risk factors are the same as for stroke and heart disease: history of smoking, lack of exercise and poor diet. It's rarer than Parkinson's disease, which affects about 1 million Americans. In contrast, roughly 20,000 people have been told they have vascular parkinsonism. ___ Q: HOW IS IT TREATED? A: Since the condition does not respond well to drugs used to treat Parkinson's disease, treatment relies on lowering the risk factors for stroke. That means quitting smoking, exercising, eating a healthy diet and perhaps taking a daily aspirin. Preventing falls is important, so a patient may receive physical therapy to improve balance. ___ Q: WHAT CAUSES THE DISEASE? A: This is where answers get tricky. Conventional thinking says the disease is caused by strokes. But without a perfect test, lots of problems get lumped under the umbrella. Espay has written a paper questioning whether most parkinsonism is related to vascular disease. He's also debated the topic at a recent neurology conference. ___ Q: IS THERE A CURE? A: Physical therapy can help with balance and walking, but the damage cannot be reversed, said Dr. Corneliu Luca, assistant professor of neurology at University of Miami. "If you do not control risk factors for stroke, they can have another stroke, and the walking can get even worse," Luca said. ___ Q: WHAT COMPLICATIONS ARE MOST WORRISOME? A: Falls are the biggest concern because they can lead to fractures, Simuni said. Bush took a spill in 2015 and fractured his C2 vertebra, the second one below the skull. It's not known whether that fall was directly related to parkinsonism. ___ Follow AP Medical Writer Carla K. Johnson on Twitter at https://twitter.com/CarlaKJohnson .
Pacific Cove's insight:
Former President George H.W. Bush, who has been placed in intensive care at a Houston hospital, is suffering from pneumonia and has vascular parkinsonism, a rare syndrome that mimics Parkinson's disease
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Exercise Can Be a Boon to People With Parkinson’s Disease

Exercise Can Be a Boon to People With Parkinson’s Disease | Parkinson's &  ALS Disease | Scoop.it
An exercise regimen, while not a cure, can alleviate Parkinson’s symptoms and slow progression of the disease.
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“The exercises opened me up,” said Ms. Sills, allowing such symptoms as small steps, slow movements and tiny, cramped handwriting to subside.
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Parkinson’s ‘game changer’ – New research says it starts in the gut and NOT the brain

Parkinson’s ‘game changer’ – New research says it starts in the gut and NOT the brain | Parkinson's &  ALS Disease | Scoop.it
SCIENTISTS have performed a complete about turn on the thinking on the causes of Parkinson’s disease, saying the condition may be caused by damage to the gut rather than the brain.
Pacific Cove's insight:
The degenerative disease involves the death of neutrons in the brain which cause tremors, stiffness and problems with mobility. Drugs are available to help combat the disease but they become less effective as the disease develops.
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This Personality Trait Raises Parkinson's Disease Risk - PsyBlog

This Personality Trait Raises Parkinson's Disease Risk - PsyBlog | Parkinson's &  ALS Disease | Scoop.it
Parkinson's disease causes problems with walking, balance and coordination -- along with a characteristic tremor.
Pacific Cove's insight:
Anxious or pessimistic people are at a higher risk of developing Parkinson’s disease, research finds.
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Potential New Treatment For Parkinson's Found - And It's An Existing Drug - PsyBlog

Potential New Treatment For Parkinson's Found - And It's An Existing Drug - PsyBlog | Parkinson's &  ALS Disease | Scoop.it
Michael J Fox, who suffers from Parkinson's, is an advocate for research into the disease.
Pacific Cove's insight:

Dr Yoon Ho Sup, one of the study’s authors, said:  “Our discovery brings hope for the millions of people suffering from Parkinson’s disease, as the drugs that we have found to have worked in the laboratory tests have already been used to treat malaria in patients for decades.  #Parkinson's #Seniors #SeinorCare #Caregivers #Caregivning 


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A Mother's Cookbook Shares More Than Recipes - New York Times

A Mother's Cookbook Shares More Than Recipes - New York Times | Parkinson's &  ALS Disease | Scoop.it
A family’s cooking history is seasoned with smudges, shorthand notations and challenging penmanship.
Pacific Cove's insight:

My mother has a kind of dementia that comes with advanced Parkinson’s. That’s lousy in a million ways, but I especially miss talking to her about cooking.  #Parkinson's #ALS #Tremors #Caregiving #Caregivers 

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A New Tool for Understanding ALS: Patients’ Brain Cells

Researchers at Johns Hopkins Medicine have transformed skin cells from patients with Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), into brain cells affected by the progressive, fatal disease and deposited those human-made cells into the first public ALS cell library, enabling scientists to better study the disease.
Pacific Cove's insight:

 “These human cellular tools will serve as a platform to understand ALS and someday discover new drugs to treat our patients,” said Rothstein, senior author. #Parkinson's #ALS #Caregving #Caregivers 

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How Deep-Brain Stimulation Reshapes Neural Circuits in Parkinson’s

How Deep-Brain Stimulation Reshapes Neural Circuits in Parkinson’s | Parkinson's &  ALS Disease | Scoop.it
Study reveals mode of action of highly effective, but poorly understood therapy.
Pacific Cove's insight:

In most Parkinson’s disease (PD) patients who receive the treatment, symptoms of slow movement, tremor, and rigidity sharply diminish soon after the stimulation device is activated, and quickly return if the device is turned off.  #Parkinsons #Tremor #Caregivers #Caregiving

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