Tissue regeneration
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Rescooped by Olga Tsigkou from Cell Therapy & Regenerative Medicine
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Facilitating neural stem/progenitor cell niche calibration for neural lineage differentiation by polyelectrolyte multilayer films

Facilitating neural stem/progenitor cell niche calibration for neural lineage differentiation by polyelectrolyte multilayer films | Tissue regeneration | Scoop.it

Via Ella Buzhor
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Ella Buzhor's curator insight, June 16, 2014 6:30 AM

Niche-modulated system comprised of polyelectrolyte multilayer (PEM) films was developed for investigation of surface effects on neural stem/progenitor cells (NSPC) differentiation. NSPCs were inducible on PEM films up to 8 alternating layers. Quantity and quality of the differentiated neurons were enhanced as the number of layers increased. This culturing stem enables high percentage functional neurons derivation without needed of any growth factors.

 

http://www.sciencedirect.com/science/article/pii/S0927776514002689

Rescooped by Olga Tsigkou from Stem Cells & Tissue Engineering
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First Autologous iPSC Bone Regeneration in Nonhuman Primate Model

First Autologous iPSC Bone Regeneration in Nonhuman Primate Model | Tissue regeneration | Scoop.it
Induced pluripotent stem cell (iPSC)-based cell therapies hold great promise for regenerative medicine, however they also carry a higher risk for tumor formation, compared to autologous mesenchymal...

Via Jacob Blumenthal
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Rescooped by Olga Tsigkou from Cell Therapy & Regenerative Medicine
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Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation

Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation | Tissue regeneration | Scoop.it
DigitalJournal.com
Stem cell breakthrough
DigitalJournal.com
A research team think that they have an answer. This will be important for use in cell therapy.

Via Ella Buzhor
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Ella Buzhor's curator insight, April 7, 2014 5:41 AM

Hydrogel system tailored to promote human pluripotent stem cell self-renewal with a chemical microenvironmental switch to direct differentiation. The timing of switching can promote specific lineage differentiation similar to in vivo. A great potential for implication in regenerative medicine.

 

http://www.pnas.org/content/early/2014/03/26/1319685111

Rescooped by Olga Tsigkou from Stem Cells & Tissue Engineering
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Researches Find Way to 3D Print Blood Vessel templates

Researches Find Way to 3D Print Blood Vessel templates | Tissue regeneration | Scoop.it

Via Jacob Blumenthal
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Jacob Blumenthal's curator insight, June 1, 2014 9:27 AM

Researchers at Brigham and Women’s Hospital (BWH) in Boston, MA have used 3D bioprinting technology to form an agarose fiber template, that can be used  a mold for blood vessels. In this way, tissue engineering researchers will be able to control the direction and distribution of new blood vessels. The same technique can be used to form agarose molds for new nerve cells and axons.