The condition known as angular cheilitis usually results from an opportunistic infection by either a bacterium or a fungus that lives naturally on the skin. This occurs because the immune system has been weakened sufficiently for them to grow and replicate in much greater numbers than they would be able to do in a healthy person. The bacteria and fungi replicate quickly in a warm, moist environment such as the mouth, which is why it can be difficult to eliminate the problem once it has developed. Many people find that natural remedies are much more effective at treating the condition than either antibiotics or antifungals, and are also more likely to prevent it from recurring again in the future.
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