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Be who you are and say what you feel because those who mind don't matter and those who matter don't mind. - Dr. Seuss
Curated by
Janet Devlin
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Apr 29
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Apr 19, 2012
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Most of the DNA alterations that are tied to disease do not alter protein-coding genes, but rather the “switches” that control them. Characterizing these switches is one of many goals of the Encyclopedia of DNA Elements (ENCODE) project.
'[This work] has revealed elements that act like dimmer switches, subtly turning up or down a gene’s activity and influencing what parts of the genome are utilized in different kinds of cells. The team characterized and mapped out the locations of thousands of these switches and signals.' Delete the scoop?
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