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Regrown nerves boost bionic ears

Regrown nerves boost bionic ears | The future of medicine and health |
Gene therapy aids performance of cochlear impants in guinea pigs.

Gene therapy delivered to the inner ear can help shrivelled auditory nerves to regrow — and in turn, improve bionic ear technology, researchers report today in Science Translational Medicine1. The work, conducted in guinea pigs, suggests a possible avenue for developing a new generation of hearing prosthetics that more closely mimics the richness and acuity of natural hearing.

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Men eat more food when they are trying to impress women, study finds

Men eat more food when they are trying to impress women, study finds | The future of medicine and health |
There are many ways that men try to impress women - be that with their wallets or their wit.

However, eating massive quantities of food is an unusual way that men innately try to show off to the female sex.

A study of 133 adults (74 males and 59 females) by Cornell University found that men consume a considerable amount more food when they are with women.

It doesn't matter what kind of food it is either - they found that not only did men eat 93% more pizza (1.44 more slices) when dining with a female than when with another man, but they also ate 86% more salad.

“These findings suggest that men tend to overeat to show off,” Kevin Kniffin, visiting assistant professor and lead author of the study, told the LA Times. “Instead of a feat of strength, it’s a feat of eating.”

Apparently, by stuffing their faces, men are showing "that they possess extraordinary skills, advantages, and/or surplus energy in degrees that are superior to other men.”

“Conspicuous consumption of food is a much less dramatic ‘risk’ than, say, going off to the front lines of war, but research on the effects of obesity nonetheless show overeating to constitute risky behavior,” added the study authors.

It also may be to show their physical fitness - which may seem an odd conclusion to draw from a pizza binge.
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Parasitic worm 'increases women's fertility' - BBC News

Parasitic worm 'increases women's fertility' - BBC News | The future of medicine and health |
Infection with a species of parasitic worm increases the fertility of women, say scientists.

A study of 986 indigenous women in Bolivia indicated a lifetime of Ascaris lumbricoides, a type of roundworm, infection led to an extra two children.

Researchers, writing in the journal Science, suggest the worm is altering the immune system to make it easier to become pregnant.

Experts said the findings could lead to "novel fertility enhancing drugs".

Nine children is the average family size for Tsimane women in Bolivia. And about 70% of the population has a parasitic worm infection.

Up to a third of the world's population also lives with such infections.

But while Ascaris lumbricoides increased fertility in the nine-year study, hookworms had the opposite effect, leading to three fewer children across a lifetime.

Prof Aaron Blackwell, one of the researchers , from the University of California Santa Barara, told the BBC News website: "The effects are unexpectedly large."

He said women's immune systems naturally changed during pregnancy so they did not reject the foetus.

Prof Blackwell said: "We think the effects we see are probably due to these infections altering women's immune systems, such that they become more or less friendly towards a pregnancy."

He said using worms as a fertility treatment was an "intriguing possibility" but warned there was far more work to be done "before we would recommend anyone try this".
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Unsupervised, Mobile and Wireless Brain–Computer Interfaces on the Horizon

Unsupervised, Mobile and Wireless Brain–Computer Interfaces on the Horizon | The future of medicine and health |
Juliano Pinto, a 29-year-old paraplegic, kicked off the 2014 World Cup in São Paulo with a robotic exoskeleton suit that he wore and controlled with his mind. The event was broadcast internationally and served as a symbol of the exciting possibilities of brain-controlled machines. Over the last few decades research into brain–computer interfaces (BCIs), which allow direct communication between the brain and an external device such a computer or prosthetic, has skyrocketed. Although these new developments are exciting, there are still major hurdles to overcome before people can easily use these devices as a part of daily life.

Until now such devices have largely been proof-of-concept demonstrations of what BCIs are capable of. Currently, almost all of them require technicians to manage and include external wires that tether individuals to large computers. New research, conducted by members of the BrainGate group, a consortium that includes neuroscientists, engineers and clinicians, has made strides toward overcoming some of these obstacles. “Our team is focused on developing what we hope will be an intuitive, always-available brain–computer interface that can be used 24 hours a day, seven days a week, that works with the same amount of subconscious thought that somebody who is able-bodied might use to pick up a coffee cup or move a mouse,” says Leigh Hochberg, a neuroengineer at Brown University who was involved in the research. Researchers are opting for these devices to also be small, wireless and usable without the help of a caregiver.
Lucile Debethune's curator insight, November 22, 12:48 PM

Une approche intéressante de l'interface homme machine,  et le groupe Braingate apporte de très bonne idées sur ce sujet.A surveiller


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Google Aims a $50 Million Moonshot at Curing Heart Disease

Google Aims a $50 Million Moonshot at Curing Heart Disease | The future of medicine and health |
Cardiovascular disease kills more people on Earth than anything else—over 17 million a year, and the number keeps going up. Of those deaths, more than 40 percent is due to coronary heart disease. Medicine has drugs that can treat it and practices that can help prevent it, but nobody really knows what causes it or how to cure it. Now, Google and the American Heart Association aim to change that by dropping a $50 million funding bomb on the problem. And as you might expect from a Silicon Valley giant that believes in moving fast and breaking things—an approach that hasn’t always transferred well to basic scientific research—the company isn’t spreading the money around.

In an announcement this month at the American Heart Association meeting in Orlando, Florida, Google Life Sciences and the AHA said the money would go to one team over five years. This isn’t covering the bases. This is, to mix a lot of metaphors, a Manhattan Project. Or as Google likes to call such things: a moonshot.
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How the Western Diet Has Derailed Our Evolution - Issue 30: Identity - Nautilus

How the Western Diet Has Derailed Our Evolution - Issue 30: Identity - Nautilus | The future of medicine and health |
For the microbiologist Justin Sonnenburg, that career-defining moment—the discovery that changed the trajectory of his research, inspiring him to study how diet and native microbes shape our risk for disease—came from a village in the African hinterlands.

A group of Italian microbiologists had compared the intestinal microbes of young villagers in Burkina Faso with those of children in Florence, Italy. The villagers, who subsisted on a diet of mostly millet and sorghum, harbored far more microbial diversity than the Florentines, who ate a variant of the refined, Western diet. Where the Florentine microbial community was adapted to protein, fats, and simple sugars, the Burkina Faso microbiome was oriented toward degrading the complex plant carbohydrates we call fiber.

Scientists suspect our intestinal community of microbes, the human microbiota, calibrates our immune and metabolic function, and that its corruption or depletion can increase the risk of chronic diseases, ranging from asthma to obesity. One might think that if we coevolved with our microbes, they’d be more or less the same in healthy humans everywhere. But that’s not what the scientists observed.
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Vaccine shows promise as cheap, effective treatment for prevention of high cholesterol

Vaccine shows promise as cheap, effective treatment for prevention of high cholesterol | The future of medicine and health |
Cholesterol in the body serves an important role by producing vitamin D, hormones and other molecules that help in our food digestion. But when the protein known as PCSK9, which dictates its levels in our blood, retains too much of it, arteries begin to clog up and increase the risk of heart disease and stroke. Researchers have now developed a vaccine that inhibits the activity of this particular protein, which reduces cholesterol levels in animals and suggests a cheap and effective way to prevent dangerously high levels in humans mightn't be so far away.

A common approach to keeping cholesterol in check (outside of regular diet and exercise) has centered on statins, a class of drugs that reduce the concentration of "bad" cholesterol, known as low-density lipoprotein cholesterol (LDL-C), in the blood. Research has indicated that it is effective in cutting the chances of cardiovascular disease, with one study even suggesting fast food outlets provide free statins to customers to cancel out the health risks posed by burgers and fries.

Millions of Americans take statins to lower cholesterol, but one of its major drawbacks is its list of side effects, which includes muscle pain, heightened diabetes risk and even cognitive loss. Pharmaceutical companies have made progress toward drugs that target PCSK9, with some found to reduce LDL-C levels by as much as 60 percent receiving approval from the Food and Drug Administration. The trouble is, these drugs don't come cheap, carrying a price tag of more than US$10,000 a year.
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Stretchy implants might stop untreatable pain - Futurity

Stretchy implants might stop untreatable pain - Futurity | The future of medicine and health |
Researchers are testing flexible wireless implants that could be used in different parts of the body to fight pain that doesn’t respond to other therapies.

Unlike devices that need to anchored to bone, these are soft and stretchable, which means they can be implanted into parts of the body that move, says Robert W. Gereau, one of the study leaders and an anesthesiology professor at Washington University School of Medicine in St. Louis.

“Our eventual goal is to use this technology to treat pain in very specific locations by providing a kind of ‘switch’ to turn off the pain signals long before they reach the brain,” says Gereau.

“But when we’re studying neurons in the spinal cord or in other areas outside of the central nervous system, we need stretchable implants that don’t require anchoring,” he adds.

The new devices are held in place with sutures. Like the previous models, they contain microLED lights that can activate specific nerve cells. Gereau hopes to use the implants to blunt pain signals in patients who have pain that cannot be managed with standard therapies.
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Exponential Medicine: Deep Learning AI Better Than Your Doctor at Finding Cancer - Singularity HUB

Exponential Medicine: Deep Learning AI Better Than Your Doctor at Finding Cancer - Singularity HUB | The future of medicine and health |
On Monday, Google released the code for its deep learning software TensorFlow into the wild. Deep learning is responsible for some of Google’s most advanced services, including recent additions like auto-reply emails and image search. But by making the code free to anyone, the company hopes to accelerate progress in deep learning software and the machine learning field more generally.

“Google is five to seven years ahead of the rest of the world,” Chris Nicholson, who runs a deep learning startup called Skymind told Wired. “If they open source their tools, this can make everybody else better at machine learning.”

That’s a big deal because the field is already moving incredibly fast.

Howard noted that long-imagined capabilities like real-time translation and computer-generated art didn’t exist just a few years ago. Even Google’s auto-reply emails (recently announced) were an April Fool’s joke back in 2011.

Computers are now capable of all of these things and more.

“So, something amazing has happened that’s caused an April Fool’s joke from just four years ago to be something that’s actually a real technology today,” Howard said.
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Change in sense of humour 'a sign of impending dementia' - BBC News

Change in sense of humour 'a sign of impending dementia' - BBC News | The future of medicine and health |
An increasingly warped sense of humour could be an early warning sign of impending dementia, say UK experts.

The University College London study involved patients with frontotemporal dementia, with the results appearing in the Journal of Alzheimer's Disease.

Questionnaires from the friends and family of the 48 patients revealed many had noticed a change in humour years before the dementia had been diagnosed.

This included laughing inappropriately at tragic events.

Experts say more studies are now needed to understand how and when changes in humour could act as a red flag for dementia.

There are many different types of dementia and frontotemporal dementia is one of the rarer ones.

The area of the brain it affects is involved with personality and behaviour, and people who develop this form of dementia can lose their inhibition, become more impulsive and struggle with social situations.
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Baby girl is first in the world to be treated with 'designer immune cells'

Baby girl is first in the world to be treated with 'designer immune cells' | The future of medicine and health |
A baby girl with aggressive leukaemia has become the first in the world to be treated with designer immune cells that were genetically engineered to wipe out her cancer.

The one-year-old, Layla Richards, was given months to live after conventional treatments failed to eradicate the disease, but she is now cancer free and doing well, a response one doctor described as “almost a miracle”.
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Meet the Parasites That Control Human Brains - The Crux

Meet the Parasites That Control Human Brains - The Crux | The future of medicine and health |
It’s time to enjoy some monster stories, and the scariest monsters of all are those that actually exist.

Join us as we share tales of some of the creepiest parasites around — those that control the brains of their human hosts, sometimes leaving insanity and death in their wake. These are the tales of neurological parasites.
The Feline Parasite

Toxoplasma gondii tops the list as the most famous — and most controversial — neurological parasite. This tiny protozoan doesn’t look like much more than a blob, but once it makes its way to the brain, it can radically alter the behavior of hosts like rats, cats and, yes, even humans.

T. gondii’s life begins in cat feces, where its eggs (known as “oocytes” or “egg cells”) wait to be picked up by carriers like rats. Once they’re safe and warm in the guts of their temporary hosts, the oocytes morph into tachyzoites, the unassuming little blobs that can really do some damage. Those tachyzoites migrate into their hosts’ muscles, eyes and brains, where they can remain hidden for decades without doing much of anything.
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The man who invented relaxation - BBC News

The man who invented relaxation - BBC News | The future of medicine and health |
People suffering from stress can tackle it in various ways - from counselling sessions to yoga classes or listening to mindfulness CDs. But it's only recently that sleeping and doing very little - the ways human beings have always rested - have come to be seen as an insufficient response to life's difficulties.

Paul Lehrer lay on a couch looking at the ceiling of a room on the third floor of the Commodore Hotel in New York and tried to relax.

But it wasn't, he recalls, "the most ideally relaxing situation". There was no music playing softly on the stereo, no aromatherapy or tea lights. Instead, because of the heat, the windows were thrown open and the air was filled with the fumes of buses and trucks. Lehrer's ears hummed with the clanging of the construction site across the street, where they were putting up a new skyscraper, and underneath that cacophony he could hear the bustle of Grand Central Station next door.

Worst of all, every few minutes an old man would come into the room and sharply upbraid him for not relaxing the right way. It was 1973 and Lehrer, a psychotherapist, had come to be treated and to train under an 85-year-old doctor called Edmund Jacobson.

Forty-four years earlier, in 1929, Jacobson had published a forbiddingly technical book called Progressive Relaxation, which detailed a procedure for removing muscular tension. But since the exercises in the book were designed to relieve pressure that was as much psychological as physical, Jacobson's work led to a surge in the use of the word "relax", in the sense of "to become less tense, anxious or stressed, to calm down".

Jacobson's book asks patients to tighten their muscles and then release them slowly, paying close attention to the sensations of tiny amounts of residual tension. The idea is that after much practice, they become able to detect any tension and then work on eliminating it.
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2 Companies Seek FDA Approval for Brain Games to Treat ADHD

2 Companies Seek FDA Approval for Brain Games to Treat ADHD | The future of medicine and health |
From baby boomers fearing memory loss to college students wanting a mental boost, interest in brain-training products is soaring. Yet among leading scientists, there is persistent scrutiny and skepticism. Last year 70 cognitive researchers signed a statement speaking out against computer-based games that promise better cognitive performance, citing a lack of scientific evidence to back such claims.

Within this morass of hype and hope, at least two companies have committed to rigorous testing of their digital products to treat specific health conditions before making them available on the market. Boston-based Akili Interactive Labs and Posit Science in San Francisco are preparing to conduct controlled clinical trials in order to have their therapeutic games approved by the U.S. Food and Drug Administration—a requirement for medical devices that doctors prescribe. The road to FDA approval is long and expensive but promising preliminary studies have encouraged both companies to move forward. The games under development at the two companies emerged from neuroscience and aging research at the University of California, San Francisco (U.C.S.F.).
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Working vocal cords grown from human cells

Working vocal cords grown from human cells | The future of medicine and health |
Vocal cords that produce realistic sounds have been grown in the lab from human cells.

The work marks a first step towards better treatments for patients who lose their voices to injury or disease.

Vocal cords are formed by two bands of smooth muscle tissue that are lined with a material called mucosa. When air passes through them, the folds vibrate hundreds of times per second to make sounds.

But diseases such as cancer can destroy the delicate folds and for many patients, the medical treatments are limited. Some patients with damaged vocal cords have viscous materials injected to make the folds more pliable. Others improve with voice coaching.

Researchers in the US took a different approach and grew layers of vocal cord cells onto scaffolds that produced tough elastic tissue similar to those within the natural voice box. When doctors tested the lab-grown tissue in voice boxes taken from dead dogs, they found they produced the same sounds as the natural tissue.

“Voice is a pretty amazing thing, yet we don’t give it much thought until something goes wrong,” said lead researcher Nathan Welham at the University of Wisconsin-Madison. “The ability to vibrate and make sounds is pretty remarkable and unique to this part of the body.”
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Vocal cords have been grown in a lab for the first time (Wired UK)

Vocal cords have been grown in a lab for the first time (Wired UK) | The future of medicine and health |
Vocal cord tissue has been grown in the lab for the first time, paving the way for potentially revolutionary treatments for people who have lost their vocal cords.

Stars such as Adele, Frank Ocean and John Mayer have been afflicted with vocal cord damage -- and have undergone extensive, and expensive, treatment to deal with it. But now researchers have found a solution to outdated ways of dealing with vocal cord damage -- by growing them in a lab.

Previous vocal cord treatment required patients, who had received transplanted cords from cadavers, to be injected with huge doses of immunosuppresants. But a team from the University of Wisconsin Medical School has come up with a new way of transplanting cords. They successfully grew 170 sets of vocal cords in a lab -- cords that don't require the usual round of immunosuppresants.
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Antibiotic resistance: World on cusp of 'post-antibiotic era' - BBC News

Antibiotic resistance: World on cusp of 'post-antibiotic era' - BBC News | The future of medicine and health |
The world is on the cusp of a "post-antibiotic era", scientists have warned after finding bacteria resistant to drugs used when all other treatments have failed.

Their report, in the Lancet, identifies bacteria able to shrug off colistin in patients and livestock in China.

They said that resistance would spread around the world and raised the spectre of untreatable infections.

Experts said the worrying development needed to act as a global wake-up call.

Bacteria becoming completely resistant to treatment - also known as the antibiotic apocalypse - could plunge medicine back into the dark ages.

Common infections would kill once again, while surgery and cancer therapies, which are reliant on antibiotics, would be under threat.
Key players

Chinese scientists identified a new mutation, dubbed the MCR-1 gene, that prevented colistin from killing bacteria.

It was found in a fifth of animals tested, 15% of raw meat samples and in 16 patients.
Eben Lenderking's curator insight, November 19, 10:02 AM

How do you stop it?  In most of the developing world it is possible to self-subscribe and walk into any pharmacy and just pick up whatever drugs you want.  In the end, the earth will "figure out" a way to reduce human population numbers if we haven't already dealt with it through war.

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First Human Tests of Memory Boosting Brain Implant a Big Leap Forward - Singularity HUB

First Human Tests of Memory Boosting Brain Implant a Big Leap Forward - Singularity HUB | The future of medicine and health |
“You have to begin to lose your memory, if only bits and pieces, to realize that memory is what makes our lives. Life without memory is no life at all.” — Luis Buñuel Portolés, Filmmaker

Every year, hundreds of millions of people experience the pain of a failing memory.

The reasons are many: traumatic brain injury, which haunts a disturbingly high number of veterans and football players; stroke or Alzheimer’s disease, which often plagues the elderly; or even normal brain aging, which inevitably touches us all.

Memory loss seems to be inescapable. But one maverick neuroscientist is working hard on an electronic cure. Funded by DARPA, Dr. Theodore Berger, a biomedical engineer at the University of Southern California, is testing a memory-boosting implant that mimics the kind of signal processing that occurs when neurons are laying down new long-term memories.

The revolutionary implant, already shown to help memory encoding in rats and monkeys, is now being tested in human patients with epilepsy — an exciting first that may blow the field of memory prosthetics wide open.

To get here, however, the team first had to crack the memory code.
Jon Pratlett's curator insight, November 19, 5:09 PM

There are times when I could use this!

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Electronic Band-Aid shapes as alternative to antibiotics

Electronic Band-Aid shapes as alternative to antibiotics | The future of medicine and health |
Bandages are important for stopping germs from entering a wound and making things worse, but could they play a more active role in making things better? New research has brought the idea of wound-healing dressings closer to reality by establishing a method of electrical stimulation that kills off the majority of multi-drug resistant bacterium commonly found in difficult-to-treat infections.

Electrical stimulation has long been explored as a means of speeding up the healing process, but exactly how it works hasn't always been so clear. However, a study earlier this year suggested it does so by triggering a process called angiogenesis, which causes new blood vessels to form and boosts blood flow to the affected area.

In the view of Washington State University researchers, at least part of the answer lies in the results of the electrochemical reaction that takes place as the current is applied. The team found that during this process hydrogen peroxide forms at the electrode surface, which as it turns out, works effectively as a disinfectant.

The team applied the electric current to a film of bacteria (multi-drug resistant Acinetobacter baumannii strain) where it killed almost the entire population within 24 hours, reducing it to 1/10,000th of its original size. The approach was also observed on pig tissue, where it killed the majority of the bacteria without affecting the surrounding healthy tissue.
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Exponential Medicine: What to Expect When You're Expecting Designer Babies - Singularity HUB

Exponential Medicine: What to Expect When You're Expecting Designer Babies - Singularity HUB | The future of medicine and health |
For thousands of years, Metzl says, we’ve been a relatively stable species, subject to the natural world’s slow evolutionary rules. But this is all about to change.

“We are now at the beginning of an evolutionary phase guided by a different set of rules of self-evolution, driven by new technologies,” Metzl said.

Metzl explains it like this. If an infant from a thousand years ago were transported into today’s world and raised by a typical family, the child would be pretty similar to a kid born in 2015. But reach a thousand years into the future and bring an infant into today’s world—and comparatively, the future child would be superhuman.

Metzl splits the oncoming transformation of the human species into three phases in human genetic engineering.
Phase One: Embryo Selection

In-vitro fertilization (IVF) reinvented treatment for women with common forms of infertility. Now, pre-implantation genetic diagnosis (PGD) enables disease detection in an embryo as young as five days. Eventually, we’ll be able to identify polygenic traits, mendelian traits, do full genomic analyses, and select embryos for implantation based on what we find.

At first, we’ll select against genetic diseases. But that may lead to selection of other traits too.

“We're going to understand not just which child is a carrier for Huntington's disease, but we're going to be able to know everything that is knowable through the genome,” says Metzl.

Stephen Hsu, vice president of research and professor of theoretical physics at Michigan State University, for example, believes that superintelligent humans are coming, and that in roughly ten years we’ll be able to predict an individual’s IQ from a cell.
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Breakthrough Prize for Illuminating the Brain's Secret Code

Breakthrough Prize for Illuminating the Brain's Secret Code | The future of medicine and health |
Optogenetics is probably the biggest buzzword in neuroscience today. It refers to techniques that use genetic modification of cells so they can be manipulated with light. The net result is a switch that can turn brain cells off and on like a bedside lamp.

The technique has enabled neuroscientists to achieve previously unimagined feats and two of its inventors—Karl Deisseroth of Stanford University and the Howard Hughes Medical Institute and Ed Boyden of Massachusetts Institute of Technology—received a Breakthrough Prize in the life sciences on November 8 in recognition of their efforts. The technology is able to remotely control motor circuits—one example is having an animal run in circles at the flick of a switch. It can even label and alter memories that form as a mouse explores different environments. These types of studies allow researchers to firmly establish a cause-and-effect relationship between electrical activity in specific neural circuits and various aspects of behavior and cognition, making optogenetics one of the most widely used methods in neuroscience today.
Jon Pratlett's curator insight, November 19, 5:11 PM

Stay tuned. This will be huge.

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Memory-Boosting Devices Tested in Humans

Memory-Boosting Devices Tested in Humans | The future of medicine and health |
A strategy designed to improve memory by delivering brain stimulation through implanted electrodes is undergoing trials in humans. The US military, which is funding the research, hopes that the approach might help many of the thousands of soldiers who have developed deficits to their long-term memory as a result of head trauma. At the Society for Neuroscience meeting in Chicago, Illinois, on October 17–21, two teams funded by the Defense Advanced Research Projects Agency presented evidence that such implanted devices can improve a person’s ability to retain memories.

By mimicking the electrical patterns that create and store memories, the researchers found that gaps caused by brain injury can be bridged. The findings raise hopes that a ‘neuro­prosthetic’ that automatically enhances flagging memory could aid not only brain-injured soldiers, but also people who have had strokes—or even those who have lost some power of recall through normal ageing.

Because of the risks associated with surgically placing devices in the brain, both groups are studying people with epilepsy who already have implanted electrodes. The researchers can use these electrodes both to record brain activity and to stimulate specific groups of neurons. Although the ultimate goal is to treat traumatic brain injury, these people might benefit as well, says biological engineer Theodore Berger at the University of Southern California (USC) in Los Angeles. That is because repeated seizures can destroy the brain tissue needed for long-term-memory formation.
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And virus makes four We may be infected — and protected — from our earliest days of development

And virus makes four We may be infected — and protected — from our earliest days of development | The future of medicine and health |
The next time you start to feel special, keep in mind that much of your DNA isn’t even yours. In fact, your genome is littered with the ancient corpses of viral invaders of hundreds (or even millions) of years ago. Basically, each of us is just a giant junk heap.

If you find that dispiriting, here’s another bit of unsettling news: Some of these skeletons come back to life during very early human development. The viral DNA makes viral proteins, which assemble themselves into something that looks suspiciously like infectious viral particles.

“It’s both fascinating and a little creepy,” says Joanna Wysocka, PhD, Stanford associate professor of developmental biology and of chemical and systems biology. “We can’t say yet whether these viral particles can be infectious, but regardless of whether they are, viral proteins within a cell are rarely completely inert.”

Wysocka described the phenomenon in a paper published earlier this year in Nature. Graduate student Edward Grow was the study’s first author.

The finding raises questions as to who, or what, is really pulling the strings during human embryogenesis. Grow and Wysocka have found that these viral proteins are well-placed to manipulate some of the earliest steps in our development by affecting gene expression and even possibly protecting the embryo’s cells from further viral infection.

It’s unclear, however, whether we are watching an ongoing battle between viruses and humans or the outcome of an uneasy truce hashed out over tens of thousands of years of evolution.

“Does the virus selfishly benefit by switching itself on in these early embryonic cells?” wonders Grow. “Or is the embryo instead commandeering the viral proteins to protect itself? Can they both benefit? That’s possible, but we don’t really know.”
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Your mood swings may give you an evolutionary advantage (Wired UK)

Your mood swings may give you an evolutionary advantage (Wired UK) | The future of medicine and health |
We already know that mood affects the way we judge and perceive things -- and it's generally considered to be negative. Studies have found that bad or sad moods can affect our judgement and reasoning, with clinical depression even having an impact on perception of time.

But a new study suggests that mood, and extreme changes in mood, may actually be "an evolutionary relic that may have been advantageous for early humans".

The study, conducted by a team at UCL and published in Trends in Cognitive Science, found that mood influences our perception of reward outcomes "such that outcomes are perceived as better when one is in a good mood relative to when one is in a bad mood". This change in mood leads to a subsequent change in behaviour -- and thus allows us to adapt to fast moving environmental factors.
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High-tech comb uses plasma to kill lice

High-tech comb uses plasma to kill lice | The future of medicine and health |
As some parents will already know, head lice infestations can be very difficult to treat. Typically a toxic shampoo or lotion has to first be applied to the sufferer's scalp, after which the lice are removed by pulling a specialized comb through their hair. Louse eggs aren't harmed by such shampoos, however, so the treatment needs to be repeated once they've hatched. This means more nasty chemicals, and more discomfort for the child (or adult). That's why researchers at Germany's Fraunhofer Institute for Surface Engineering and Thin Films have developed an alternative, in the form of a comb that zaps the pests with cold plasma.

Already in use in some German pediatric clinics, the comb has conductive teeth that serve as electrodes. When electrical pulses are sent to those teeth, the air space between them is ionized, generating plasma. Exposure to that plasma kills both adult lice and their eggs, which are known as nits.

Because the pulses are very short, however, the plasma is no warmer than room temperature. Therefore, there's no danger of burns or singeing to the patient.

Just one treatment reportedly kills half of the lice and nits immediately, with the other half dying within a day. No chemicals or second treatments are required.
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Just one junk-food snack triggers signals of metabolic syndrome | KurzweilAI

Just one junk-food snack triggers signals of metabolic syndrome | KurzweilAI | The future of medicine and health |
Just one high-calorie milkshake was enough to make metabolic syndrome worse for some people. And overindulgence in just a single meal or snack (especially junk food) is enough to trigger the beginnings of metabolic syndrome, which is associated with the risk of developing cardiovascular disease and diabetes (obesity around the waist and trunk is the main sign).

That finding by researchers at the Microbiology and Systems Biology Group of the Netherlands Organisation for Applied Scientific Research (TNO) was reported in the online edition of the Nov. 2015 issue of The FASEB Journal.

For some people, “acute effects of diet are mostly small, but may have large consequences in the long run,” said TNO researcher Suzan Wopereis, Ph.D., senior author of the report.

The researchers gave male volunteers in two groups a high-fat milkshake consisting of 53% whipping cream, 3% sugar, and 44% water (1.6 g protein, 16 g fat, and 3.2 g carbohydrates).

The first group included 10 healthy male volunteers. They were also given a snack diet consisting of an additional 1300 kcal per day, in the form of sweets and savory products such as candy bars, tarts, peanuts, and crisps for four weeks.

The second group included nine volunteers with metabolic syndrome and who had a combination of two or more risk factors for heart disease, such as unhealthy cholesterol levels, high blood pressure, high blood sugar, high blood lipids, and abdominal fat.

Test results: not good

Both groups had blood samples taken, before and after the snacks. In these blood samples, the researchers measured 61 biomarkers, such as cholesterol and blood sugar.

For the subjects with metabolic syndrome, the blood tests showed that biochemical processes related to sugar metabolism, fat metabolism, and inflammation were abnormal.

For the 10 healthy male volunteers, the blood tests showed that signaling molecules such as hormones regulating the control of sugar and fat metabolism and inflammation were changed, resembling the very subtle start of negative health effects similar to those found at the start of metabolic disease.

“Eating junk food is one of those situations where our brains say ‘yes’ and our bodies say ‘no,’” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. “Unfortunately for us, this report shows that we need to use our brains and listen to our bodies. Even one unhealthy snack has negative consequences that extend far beyond any pleasure it brings.”
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