Four women have had new vaginas grown in the laboratory and implanted by doctors in the US.
A tissue sample and a biodegradable scaffold were used to grow vaginas in the right size and shape for each woman as well as being a tissue match.
They all reported normal levels of "desire, arousal, lubrication, orgasm, satisfaction" and painless intercourse.
Experts said the study, published in the Lancet, was the latest example of the power of regenerative medicine.
'I feel fortunate'
In each woman the vagina did not form properly while they were still inside their mother's womb, a condition known as vaginal aplasia.
Current treatments can involve surgically creating a cavity, which is then lined with skin grafts or parts of the intestine.